de Manuel, MarcKuhlwilm, MartinSousa, Victor C.Prado Martínez, Javier, 1987-Hernández Rodríguez, Jéssica, 1983-Dupanloup, IsabelleLao Grueso, Oscar, 1976-Heredia Genestar, José María, 1985-Kuderna, Lukas, 1989-Casals López, FerranAngedakin, SamuelArandjelovic, MimiBoesch, ChristopheKühl, Hjalmar S.Vigilant, LindaNavarro i Cuartiellas, Arcadi, 1969-Excoffier, LaurentMarquès i Bonet, Tomàs, 1975-2018-12-052018-12-052016de Manuel M, Kuhlwilm M, Frandsen P, Sousa VC, Desai T, Prado-Martinez J et al. Chimpanzee genomic diversity reveals ancient admixture with bonobos. Science. 2016 Oct 28;354(6311):477-48. DOI: 10.1126/science.aag26020036-8075http://hdl.handle.net/10230/35987Our closest living relatives, chimpanzees and bonobos, have a complex demographic history. We analyzed the high-coverage whole genomes of 75 wild-born chimpanzees and bonobos from 10 countries in Africa. We found that chimpanzee population substructure makes genetic information a good predictor of geographic origin at country and regional scales. Multiple lines of evidence suggest that gene flow occurred from bonobos into the ancestors of central and eastern chimpanzees between 200,000 and 550,000 years ago, probably with subsequent spread into Nigeria-Cameroon chimpanzees. Together with another, possibly more recent contact (after 200,000 years ago), bonobos contributed less than 1% to the central chimpanzee genomes. Admixture thus appears to have been widespread during hominid evolution.application/pdfengThis is the author’s version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science on Volume 354, number 6311, 2016. DOI: 10.1126/science.aag2602Evolució molecularGenèticaBonobo -- GenèticaXimpanzés -- Genèticainfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1126/science.aag2602info:eu-repo/semantics/openAccess