Mallorquí Bagué, JoaquimLozano Madrid, MaríaVintró Alcaraz, CristinaForcano, LauraDíaz López, AndrésGalera, AnaFernández-Carrión, RebecaGranero, RoserJiménez Murcia, SusanaCorella, DoloresPintó Sala, XavierCuenca Royo, Aida Ma, 1981-Bulló, MònicaSalas Salvadó, JordiTorre Fornell, Rafael de laFernández Aranda, Fernando2021-06-092021-06-092021Mallorquí-Bagué N, Lozano-Madrid M, Vintró-Alcaraz C, Forcano L, Díaz-López A, Galera A, Fernández-Carrión R, Granero R, Jiménez-Murcia S, Corella D, Pintó X, Cuenca-Royo A, Bulló M, Salas-Salvadó J, de la Torre R, Fernández-Aranda F. Effects of a psychosocial intervention at one-year follow-up in a PREDIMED-plus sample with obesity and metabolic syndrome. Sci Rep. 2021;11(1):9144. DOI: 10.1038/s41598-021-88298-12045-2322http://hdl.handle.net/10230/47809This study examines if overweight/obesity are related to higher impulsivity, food addiction and depressive symptoms, and if these variables could be modified after 1 year of a multimodal intervention (diet, physical activity, psychosocial support). 342 adults (55-75 years) with overweight/obesity and metabolic syndrome (MetS) from the PREDIMED-Plus Cognition study were randomized to the intervention or to the control group (lifestyle recommendations). Cognitive and psychopathological assessments were performed at baseline and after 1-year follow-up. At baseline, higher impulsivity was linked to higher food addiction and depressive symptoms, but not to body mass index (BMI). Food addiction not only predicted higher BMI and depressive symptoms, but also achieved a mediational role between impulsivity and BMI/depressive symptoms. After 1 year, patients in both groups reported significant decreases in BMI, food addiction and impulsivity. BMI reduction and impulsivity improvements were higher in the intervention group. Higher BMI decrease was achieved in individuals with lower impulsivity. Higher scores in food addiction were also related to greater post-treatment impulsivity. To conclude, overweight/obesity are related to higher impulsivity, food addiction and depressive symptoms in mid/old age individuals with MetS. Our results also highlight the modifiable nature of the studied variables and the interest of promoting multimodal interventions within this population.application/pdfeng© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.info:eu-repo/semantics/articlehttp://dx.doi.org/10.1038/s41598-021-88298-1Human behaviourPsychologyinfo:eu-repo/semantics/openAccess