Di Somma, Albertode Notaris, MatteoStagno, VitaSerra, LuisEnseñat, JoaquimAlobid, IsamSan Molina, JoanBerenguer, JuanCappabianca, PaoloPrats-Galino, Alberto2023-12-122023-12-122014Di Somma A, de Notaris M, Stagno V, Serra L, Enseñat J, Alobid I, et al. Extended endoscopic endonasal approaches for cerebral aneurysms: anatomical, virtual reality and morphometric study. BioMed Research International. 2014 Jan 19;703792:1-9. DOI: 10.1155/2014/7037922314-6133http://hdl.handle.net/10230/58512Introduction. The purpose of the present contribution is to perform a detailed anatomic and virtual reality three-dimensional stereoscopic study in order to test the effectiveness of the extended endoscopic endonasal approaches for selected anterior and posterior circulation aneurysms. Methods. The study was divided in two main steps: (1) simulation step, using a dedicated Virtual Reality System (Dextroscope, Volume Interactions); (2) dissection step, in which the feasibility to reach specific vascular territory via the nose was verified in the anatomical laboratory. Results. Good visualization and proximal and distal vascular control of the main midline anterior and posterior circulation territory were achieved during the simulation step as well as in the dissection step (anterior communicating complex, internal carotid, ophthalmic, superior hypophyseal, posterior cerebral and posterior communicating, basilar, superior cerebellar, anterior inferior cerebellar, vertebral, and posterior inferior cerebellar arteries). Conclusion. The present contribution is intended as strictly anatomic study in which we highlighted some specific anterior and posterior circulation aneurysms that can be reached via the nose. For clinical applications of these approaches, some relevant complications, mainly related to the endonasal route, such as proximal and distal vascular control, major arterial bleeding, postoperative cerebrospinal fluid leak, and olfactory disturbances must be considered.application/pdfengCopyright © 2014 Alberto Di Somma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.EndoscòpiaAneurismes cerebralsImatgeria tridimensional en medicinainfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1155/2014/703792info:eu-repo/semantics/openAccess