Puig, JordiSatorra, PauMartínez, AnaGonzalez, SandraGüerri Fernández, RobertoArrieta Aldea, ItziarArnau-Barrés, IsabelPrats, AnnaBuhiichyk, ViraTebé, CristianNegredo, Eugenia2025-09-082025-09-082025Puig J, Satorra P, Martínez A, González S, Güerri-Fernández R, Arrieta-Aldea I, et al. Short assessment for people with human immunodeficiency virus (HIV) aged 50 years or older: essential tests from comprehensive geriatric assessment. Viruses. 2025 Jul;17(7):887. DOI: 10.3390/v170708871999-4915http://hdl.handle.net/10230/71142Background: Comprehensive geriatric assessments (CGAs) are necessary to address the needs of people with human immunodeficiency virus infection (PWH) aged ≥ 50 years and ensure that they receive high-quality care. We aimed to identify the most effective tests from an extensive CGA to develop a short CGA. Methods: This observational, cross-sectional, and analytical study was conducted in three phases: (1) describing PWH aged ≥ 50 and matched controls; (2) jointly analyzing data to identify the most effective tests from the original CGA and develop a short version; and (3) applying the short CGA separately to both groups. Results: The most effective tests—the Lawton scale, SPPB, Barber questionnaire, Pittsburgh Sleep Quality Index, and Cognitive Complaints questionnaire—were used to create a short CGA. It identified abnormalities in 77% of PWH flagged by the full CGA, though 65% with the normal short CGA results had at least one abnormal result in the full version. Most false negatives were due to the excluded Hearing-Dependent Activities scale. Conclusions: These findings represent an initial step toward developing a short CGA for an easy and rapid identification of PWH aged ≥ 50, beyond a frailty assessment, who may benefit from early clinical management.application/pdfeng© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).info:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/v17070887HIVGeriatric assessmentAgingGeriatric syndromesPsychosocial factorsEarly managementinfo:eu-repo/semantics/openAccess