Pesqué, DavidMarch-Rodríguez, AlvaroDahlin, JakobIsaksson, MarlénePujol Vallverdú, Ramon MariaGiménez-Arnau, ElenaGiménez Arnau, Anna Maria2022-05-302022-05-302021Pesqué D, March-Rodriguez Á, Dahlin J, Isaksson M, Pujol RM, Giménez-Arnau E, et al. Bikini textile contact dermatitis: a sherlockian approach revealing 2,4-dichlorophenol as a potential textile contact allergen. Contact Dermatitis. 2021 Dec; 85(6): 679-85. DOI: 10.1111/cod.139460105-1873http://hdl.handle.net/10230/53304Background: Different textile constituents may act as allergens and/or irritants and provoke textile contact dermatitis (TCD). Objectives: To report a case of TCD caused by ethylene glycol monododecyl ether and 2,4-dichlorophenol, present in a bikini. Methods: A woman presented with an eczematous, pruritic rash in the area of the bikini straps and back. Patch testing was performed with the European baseline, textile, sunscreen, and photo-patch series, the bikini "as is", and ethanol and acetone extracts of the bikini. Thin-layer chromatography (TLC) of the extracts and gas chromatography-mass spectrometry (GC-MS) analysis were used to elucidate the culprit agents. Results: Positive reactions were found to the bikini "as is" and to the ethanol and acetone extracts. Patch testing with TLC strips showed a strong reaction to spots-fractions 3 and 4. GC-MS was performed to identify substances in each fraction and those suspected to be skin sensitisers were patch tested. On day (D) 4 positive reactions to ethylene glycol monododecyl ether (irritant reaction) and 2,4-dichlorophenol (++) were observed. Conclusion: A myriad of chemical compounds can be found in clothing. Ethylene glycol monododecyl ether and 2,4-dichlorophenol were identified as the potential culprits of this bikini TCD.application/pdfengThis is the peer reviewed version of the following article: Pesqué D, March-Rodriguez Á, Dahlin J, Isaksson M, Pujol RM, Giménez-Arnau E, et al. Bikini textile contact dermatitis: a sherlockian approach revealing 2,4-dichlorophenol as a potential textile contact allergen. Contact Dermatitis. 2021 Dec; 85(6): 679-85, which has been published in final form at http://dx.doi.org/10.1111/cod.13946. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.info:eu-repo/semantics/articlehttp://dx.doi.org/10.1111/cod.139462,4-dichlorophenolAllergic contact dermatitisEthylene glycol monododecyl etherGas chromatography-mass spectrometryIrritant contact dermatitisPatch testTextile contact dermatitisThin-layer chromatographyinfo:eu-repo/semantics/openAccess