Martínez-Sánchez, Jose M.Ballbé, MontsePérez Ortuño, Raúl, 1976-Fu, MarcelaSureda, XiscaPascual Esteban, José A.Peruga, ArmandoFernández, Esteve2019-07-242019-07-242018Martínez-Sánchez JM, Ballbè M, Pérez-Ortuño R, Fu M, Sureda X, Pascual JA et al. Secondhand exposure to aerosol from electronic cigarettes: pilot study of assessment of tobacco-specific nitrosamine (NNAL) in urine. Gac Sanit. 2019;33(6):575-8. DOI: 10.1016/j.gaceta.2018.07.0160213-9111http://hdl.handle.net/10230/42155OBJECTIVE: To assess the levels of a tobacco-specific nitrosamine (NNAL) in non-smokers passively exposed to the second-hand aerosol (SHA) emitted from users of electronic cigarettes (e-cigarettes). METHOD: We conducted an observational study involving 55 non-smoking volunteers divided into three groups: 25 living at home with conventional smokers, 6 living with e-cigarette users, and 24 in control homes (smoke-free homes). We obtained urine samples from all volunteers to determine NNAL. RESULTS: We detected NNAL in the urine of volunteers exposed to e-cigarettes (median:0.55 pg/mL; interquartile range: 0.26-2.94 pg/mL). The percentage of urine samples with quantifiable NNAL differed significantly among the three groups of homes: 29.2%, 66.7% and 76.0%, respectively (p=0.004). CONCLUSIONS: We found NNAL nitrosamine in urine samples from people exposed to SHA from e-cigarettes. However, these results could be confirmed with more studies with larger sample sizes.application/pdfeng0213-9111/© 2018 SESPAS. Publicado por Elsevier España, S.L.U. Este es un artículo Open Access bajo la licencia CC BY-NC-ND (http://creativecommons.org/licenses/by-nc-nd/4.0/).info:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.gaceta.2018.07.016BiomarcadoresBiomarkersCigarrillo electrónicoElectronic cigaretteNitrosaminasNitrosaminesSecond-hand aerosolinfo:eu-repo/semantics/embargoedAccess