Falaguera Mata, Maria José, 1994-Mestres i López, Jordi2022-06-302022-06-302021Falaguera MJ, Mestres J. Congenericity of claimed compounds in patent applications. Molecules. 2021 Aug 30; 26(17):5253. DOI: 10.3390/molecules261752531420-3049http://hdl.handle.net/10230/53644A method is presented to analyze quantitatively the degree of congenericity of claimed compounds in patent applications. The approach successfully differentiates patents exemplified with highly congeneric compounds of a structurally compact and well defined chemical series from patents containing a more diverse set of compounds around a more vaguely described patent claim. An application to 750 common patents available in SureChEMBL, SureChEMBLccs and ChEMBL is presented and the congenericity of patent compounds in those different sources discussed.application/pdfengCopyright © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).info:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/molecules26175253ChEMBLSureChEMBLSureChEMBLccsChemical seriesPatent compoundsSimilarity analysisinfo:eu-repo/semantics/openAccess