Hernández Fernández, Carlos PelayoGiménez Arnau, Anna MariaGarcía Doval, Ignacio2024-10-112024-10-112024Hernández Fernández CP, Borrego L, Giménez Arnau AM, Zaragoza Ninet V, Sanz Sánchez T, Miquel Miquel FJ, et al. Sensitization to textile dyes in Spain: Epidemiological situation (2019-2022). Contact Dermatitis. 2024 May;90(5):486-94. DOI: 10.1111/cod.145130105-1873http://hdl.handle.net/10230/61372Background: Current frequency and features for positivity to textile dye mix (TDM) in Spain are unknown. Objectives: To study the frequency, clinical features and simultaneous positivity between TDM, para-phenylenediamine (PPD) and specific disperse dyes. Materials and methods: We analysed all consecutive patients patch-tested with TDM from the Spanish Contact Dermatitis Registry (REIDAC), from 1 January 2019 to 31 December 2022. Within this group, we studied all selected patients patch-tested with a textile dye series. Results: Out of 6128 patients analysed, 3.3% were positive to the TDM and in 34% of them, the sensitization was considered currently relevant. TDM positivity was associated with working as a hairdresser/beautician and scalp, neck/trunk and arm/forearm dermatitis. From TDM-positive patients, 57% were positive to PPD. One hundred and sixty-four patients were patch-tested with the textile dye series. Disperse Orange 3 was the most frequent positive dye (16%). One of every six cases positive to any dye from the textile dye series would have been missed if patch-tested with the TDM alone. Conclusions: Positivity to TDM is common in Spain and often associated with PPD sensitization. TDM is a valuable marker of disperse dyes allergy that should be part of the Spanish and European standard series.application/pdfeng© 2024 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.info:eu-repo/semantics/articlehttp://dx.doi.org/10.1111/cod.14513SpainContact dermatitisDisperse dyesPatch testsStandard seriesTextile dye mixTextile dye seriesinfo:eu-repo/semantics/openAccess