Sarnago, HéctorBurdío, José M.García Sánchez, TomásMir, Lluis M.Álvarez Gariburo, IgnacioLucía, Óscar2020-07-082020-07-082020Sarnago H, Burdío JM, García-Sánchez T, Mir LM, Álvarez-Gariburo I, Lucía O. GaN-based versatile waveform generator for biomedical applications of electroporation. IEEE Access. 2020 May 21;8:97196-203. DOI: 10.1109/ACCESS.2020.29964262169-3536http://hdl.handle.net/10230/45087Biomedical applications often require high-performance power supplies for diagnosis and treatment systems. In particular, modern electroporation techniques for cancer treatment require high-voltage generators with versatile waveform generation. In this context, sinusoidal waveform generation has been recently identified as beneficial for electrochemotherapy cancer treatments. This paper proposes the design of a high-voltage high-frequency arbitrary waveform generator taking advantage of Gallium Nitride (GaN) devices. The proposed converter has been designed and implemented, achieving a 1-MHz 2000-V output voltage. It has been electrically tested and applied to electrochemotherapy treatments in mice, demonstrating the feasibility of this proposal.application/pdfengThis work is licensed under a Creative Commons Attribution 4.0 License. For more information, see https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/articlehttp://dx.doi.org/10.1109/ACCESS.2020.2996426ElectroporationMagnetic componentsArbitrary waveform generatorsCapacitorsWide bandgap semiconductorCancer treatmentinfo:eu-repo/semantics/openAccess