Figueira-Gonçalves, Juan MarcoBadenes Bonet, Diana, 1987-RECOVID2024-10-152024-10-152023Figueira-Gonçalves JM, García-Bello MÁ, Ramallo-Fariña Y, Méndez R, Latorre Campos A, González-Jiménez P, et al. Persistent respiratory failure and re-admission in patients with chronic obstructive pulmonary disease following hospitalization for COVID-19. Int J Chron Obstruct Pulmon Dis. 2023 Nov 7;18:2473-81. DOI: 10.2147/COPD.S4283161176-9106http://hdl.handle.net/10230/61404Background: Chronic obstructive pulmonary disease (COPD) has been associated with worse clinical evolution/survival during a hospitalization for SARS-CoV2 (COVID-19). The objective of this study was to learn the situation of these patients at discharge as well as the risk of re-admission/mortality in the following 12 months. Methods: We carried out a subanalysis of the RECOVID registry. A multicenter, observational study that retrospectively collected data on severe acute COVID-19 episodes and follow-up visits for up to a year in survivors. The data collection protocol includes general demographic data, smoking, comorbidities, pharmacological treatment, infection severity, complications during hospitalization and required treatment. At discharge, resting oxygen saturation (SpO2), dyspnea according to the mMRC (modified Medical Research Council) scale and long-term oxygen therapy prescription were recorded. The follow-up database included the clinical management visits at 6 and 12 months, where re-admission and mortality were recorded. Results: A total of 2047 patients were included (5.6% had a COPD diagnosis). At discharge, patients with COPD had greater dyspnea and a greater need for prescription home oxygen. After adjusting for age, sex and Charlson comorbidity index, patients with COPD had a greater risk of hospital re-admission due to respiratory causes (HR 2.57 [1.35-4.89], p = 0.004), with no significant differences in survival. Conclusion: Patients with COPD who overcome a serious SARS-CoV2 infection show a worse clinical situation at discharge and a greater risk of re-admission for respiratory causes.application/pdfeng© 2023 Figueira-Gonçalves et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.info:eu-repo/semantics/articlehttp://dx.doi.org/10.2147/COPD.S428316COPDCOVID-19RECOVIDSARS-CoV2SEPARSpanish COVID-19 registryChronic obstructive pulmonary diseaseCoronavirus disease 2019Respiratory failureSevere acute respiratory syndrome coronavirus 2info:eu-repo/semantics/openAccess