Jungfleisch, Jennifer, 1986-Blasco Moreno, Bernat, 1986-Díez Antón, Juana, 1962-2017-02-032017-02-032016Jungfleisch J, Blasco-Moreno B, Díez J. Use of cellular decapping activators by positive-strand RNA viruses. Viruses. 2016 Dec 21;8(12). DOI: 10.3390/v81203401999-4915http://hdl.handle.net/10230/28042Positive-strand RNA viruses have evolved multiple strategies to not only circumvent the hostile decay machinery but to trick it into being a priceless collaborator supporting viral RNA translation and replication. In this review, we describe the versatile interaction of positive-strand RNA viruses and the 5'-3' mRNA decay machinery with a focus on the viral subversion of decapping activators. This highly conserved viral trickery is exemplified with the plant Brome mosaic virus, the animal Flock house virus and the human hepatitis C virus.application/pdfeng© 2016 by Jennifer Jungfleisch, Bernat Blasco-Moreno and Juana Díez; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/)Virus RNARNA missatgerinfo:eu-repo/semantics/articlehttp://dx.doi.org/10.3390/v8120340info:eu-repo/semantics/openAccess