Gabarrell-Pascuet, AinaKoyanagi, AiFélez-Nobrega, MireiaCristóbal Narváez, PaulaMortier, PhilippeVilagut Saiz, Gemma, 1975-Olaya, BeatrizAlonso Caballero, JordiHaro Abad, Josep MariaDomènech-Abella, Joan2023-05-102023Gabarrell-Pascuet A, Koyanagi A, Felez-Nobrega M, Cristóbal-Narváez P, Mortier P, Vilagut G, Olaya B, Alonso J, Haro JM, Domènech-Abella J. The association of age with depression, anxiety, and posttraumatic stress symptoms during the COVID-19 pandemic in Spain: The role of loneliness and prepandemic mental disorder. Psychosom Med. 2023 Jan 1;85(1):42-52. DOI: 10.1097/PSY.00000000000011460033-3174http://hdl.handle.net/10230/56741Objective: Older adults may be at lower risk of common mental disorders than younger adults during the coronavirus disease 2019 (COVID-19) pandemic. Previous research has shown shown differences by age in psychosocial well-being during the pandemic and have highlighted the moderating effect of prepandemic mental disorders on that association. In this line, we examined the association of age with self-reported symptoms of loneliness, depression, anxiety, and posttraumatic stress, as well as potential roles of loneliness symptoms and prepandemic mental disorders on the association between age and mental disorder symptoms. Methods: Cross-sectional data of 2000 adults in Spain interviewed by telephone during the COVID-19 pandemic (February-March 2021) were analyzed. Depression, anxiety, and posttraumatic stress were measured with the eight-item Patient Health Questionnaire, the seven-item Generalized Anxiety Disorder Scale, and the four-item checklist for Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition), respectively. Loneliness was measured with the three-item University of California at Los Angeles Loneliness Scale. Several regression models were constructed to assess factors related to loneliness and mental disorders. Results: According to cutoff points used, 12.4% of participants revealed depression, 11.9% revealed anxiety, and 11.6% revealed posttraumatic stress. Age was negatively related to mental disorder symptoms and loneliness. Loneliness was associated with higher levels of mental disorder symptoms. This association was stronger in younger adults without prepandemic mental disorders and in older adults with them. The association between age and loneliness was stronger in those with prepandemic mental disorders. Loneliness mediated the association of age with mental disorder symptoms. Conclusions: Interventions focused on loneliness could alleviate the impact of the COVID-19 pandemic on mental health.application/pdfeng© Lippincott Williams & Wilkins "This is a non-final version of an article published in final form in Gabarrell-Pascuet A, Koyanagi A, Felez-Nobrega M, Cristóbal-Narváez P, Mortier P, Vilagut G, Olaya B, Alonso J, Haro JM, Domènech-Abella J. The association of age with depression, anxiety, and posttraumatic stress symptoms during the COVID-19 pandemic in Spain: The role of loneliness and prepandemic mental disorder. Psychosom Med. 2023 Jan 1;85(1):42-52. DOI: 10.1097/PSY.0000000000001146". http://dx.doi.org/10.1097/PSY.0000000000001146info:eu-repo/semantics/articlehttp://dx.doi.org/10.1097/PSY.0000000000001146LonelinessAgeMajor depressive disorderGeneralized anxiety disorderPosttraumatic stress disorderCOVID-19 = coronavirus disease 2019GAD = generalized anxiety disorderMDD = major depressive disorderPCL5 = PTSD Checklist for DSM-5PHQ = Patient Health Questionnaire Depression ScalePTSD = posttraumatic stress disorderinfo:eu-repo/semantics/openAccess