Repositori digital de la UPF: Enviaments recents

  • Ruetz, Tyson Joel; Pfisterer, Ulrich; Di Stefano, Bruno, 1984-; Ashmore, James; Beniazza, Meryam; Tian, Tian V.; Kaemena, Daniel F.; Tosti, Luca; Tan, Wenfang; Manning, Jonathan R.; Chantzoura, Eleni; Ottosson, Daniella Rylander; Collombet, Samuel; Johnsson, Anna E.; Cohen, Erez; Yusa, Kosuke; Linnarsson, Sten; Graf, T. (Thomas); Parmar, Malin; Kaji, Keisuke (Elsevier, 2017)
    Reprogramming of cellular identity using exogenous expression of transcription factors (TFs) is a powerful and exciting tool for tissue engineering, disease modeling, and regenerative medicine. However, generation of desired ...
  • Bosch Presegué, Laia; Raurell Vila, Helena; Thackray, Joshua K.; González, Jessica V.; Casal, Carmen; Kane-Goldsmith, Noriko; Vizoso, Miguel; Brown, Jeremy P.; Gómez, Antonio; Ausió, Juan; Zimmermann, Timo; Esteller, Manel; Schotta, Gunnar; Singh, Prim B.; Serrano, Lourdes; Vaquero, Alejandro (Elsevier, 2017)
    HP1 is a structural component of heterochromatin. Mammalian HP1 isoforms HP1α, HP1β, and HP1γ play different roles in genome stability, but their precise role in heterochromatin structure is unclear. Analysis of Hp1α-/-, ...
  • Hosp, Fabian; Gutiérrez Ángel, Sara; Schaefer, Martin H.; Cox, Jürgen; Meissner, Felix; Hipp, Mark Steffen; Hartl, F. Ulrich; Klein, Rüdiger; Dudanova, Irina; Mann, Matthias (Elsevier, 2017)
    Aggregation of polyglutamine-expanded huntingtin exon 1 (HttEx1) in Huntington's disease (HD) proceeds from soluble oligomers to late-stage inclusions. The nature of the aggregates and how they lead to neuronal dysfunction ...
  • Valles Ibáñez, Guillem de, 1986-; Hernández Rodríguez, Jessica; Laayouni, Hafid, 1968-; Cuscó Martí, Ivon, 1973-; Codina i Solà, Marta, 1988-; Batlle Masó, Laura; Solís Moruno, Manuel; Marquès i Bonet, Tomàs, 1975-; Bosch Fusté, Elena; Casals López, Ferran (Frontiers, 2018)
    Common variable immunodeficiency (CVID) is the most frequent symptomatic primary immunodeficiency characterized by recurrent infections, hypogammaglobulinemia and poor response to vaccines. Its diagnosis is made based on ...
  • Lizano Díez, Javier; Ginés-Cespedosa, Alberto; Alentorn-Geli, Eduard; Pérez-Prieto, Daniel; González-Lucena, Gemma; Gamba, Carlo; de Zabala, Santiago; Solano-López, Alberto; Rigol-Ramón, Pau (SAGE Publications, 2017)
    BACKGROUND: The effectiveness of corticosteroid injection for the treatment of Morton's neuroma is unclear. In addition, most of the studies related to it are case-control or retrospective case series. The purpose of this ...
  • Bawaked, Rowaedh Ahmed; Schröder, Helmut, 1958-; Ribas-Barba, Lourdes; Izquierdo-Pulido, Maria; Pérez-Rodrigo, Carmen; Fitó Colomer, Montserrat; Serra-Majem, Luis (Taylor & Francis (Routledge), 2017)
    Background: Diet plays a crucial role in the regulation of chronic inflammation. The sparse evidence available in adult populations indicates that diet quality is linked to the dietary inflammatory potential; however, this ...
  • Ariza, Carles; Arechavala, Teresa; Valmayor, Sara; Serral, Gemma; Moncada, Albert; Rajmil Rajmil, Luis Alberto; Schiaffino, Anna; Sánchez-Martínez, Francesca; Evaluation Group of POIBA Project (Taylor & Francis (Routledge), 2017)
    La salud de las personas ha mejorado a lo largo del siglo XX, al mismo tiempo que se consolidaba el Estado del bienestar. Este trabajo explora la relación actual del Estado del bienestar y la salud pública. Las funciones ...
  • Abner, Erik, 1986- (Universitat Pompeu Fabra, 2016-12-21)
    Tras la infección por VIH-1, el establecimiento de un depósito de células T en reposo infectadas latentemente con VIH impide la erradicación del virus en pacientes. Para lograr la erradicación, la terapia retroviral existente ...
  • Valles Ibáñez, Guillem de, 1986- (Universitat Pompeu Fabra, 2016-11-16)
    Human genomes have been found to harbor an unexpected number of ~100 loss-of-function (LoF) variants, with ~20 of them in an homozygous state, in most cases without a visible effect despite its potential truncation of ...
  • Moscoso Castro, Maria, 1988- (Universitat Pompeu Fabra, 2016-11-28)
    The adenosinergic system is a neuromodulatory complex acting on four receptor subtypes with varying distributions throughout the central nervous system. This system contributes to homeostasis and regulates several physiological ...
  • Balsiger, Alexander, 1975- (Universitat Pompeu Fabra, 2014-12-19)
    We recently identified a novel cyclin called Cyclin O which is able to bind and activate Cdk1 and Cdk2 in response to intrinsic apoptotic stimuli like DNA damage or ER stress. Cyclin O has been shown to be involved in the ...
  • Rodríguez Sanz, Maria, 1984- (Universitat Pompeu Fabra, 2016-12-15)
    New high-throughput behavioral systems enable the recording of continuous behavioral sequences with an unprecedented richness of signals and a deep temporal resolution. Automated systems offer neuroscience the opportunity ...
  • Campos Sańchez, Elena; Deleyto Seldas, Nerea; Domínguez, Verónica; Carrillo, Enrique; Ura, Kiyoe; Rocha, Pedro P.; Kim, Jung Hyun; Aljoufi, Arafat; Esteve-Codina, Anna; Dabad, Marc; Gut, Marta; Heyn, Holger; Kaneda, Yasufumi; Nimura, Keisuke; Skok, Jane Amanda; Martínez Frías, María Luísa; Cobaleda, César (Elsevier, 2017)
    Immunodeficiency is one of the most important causes of mortality associated with Wolf-Hirschhorn syndrome (WHS), a severe rare disease originated by a deletion in chromosome 4p. The WHS candidate 1 (WHSC1) gene has been ...
  • Muñoz, Manuel Javier; Nieto Moreno, Nicolás; Giono, Luciana E.; Cambindo Botto, Adrián E.; Dujardin, Gwendal; Bastianello, Giulia; Lavore, Stefania; Torres Méndez, Antonio; Menck, Carlos Frederico Martins; Blencowe, Benjamin J.; Irimia, Manuel; Foiani, Marco; Kornblihtt, Alberto R. (Elsevier, 2017)
    We have previously found that UV irradiation promotes RNA polymerase II (RNAPII) hyperphosphorylation and subsequent changes in alternative splicing (AS). We show now that UV-induced DNA damage is not only necessary but ...
  • Pedone, Elisa, 1985-; Olteanu, Vlad Aris; Marucci, Lucia; Muñoz-Martin, Maria Isabel; Youssef, Sameh A.; de Bruin, Alain; Cosma, Maria Pia, 1970- (Elsevier, 2017)
    In rodents and humans, the liver can efficiently restore its mass after hepatectomy. This is largely attributed to the proliferation and cell cycle re-entry of hepatocytes. On the other hand, bone marrow cells (BMCs) migrate ...
  • Muñoz Cánoves, Pura, 1962-; Carvajal, Jaime J.; López de Munain, Adolfo; Izeta, Ander (Frontiers, 2016)
  • Pretus, Clara; Ramos Quiroga, Josep Antoni; Richaret, Vanesa; Corrales, Montse; Picado, Marisol; Carmona, Susanna; Vilarroya, Óscar (Elsevier, 2017)
    Long-term effects of psychostimulants such as methylphenidate on ADHD patients have been proved to be difficult to capture in cross-sectional studies comparing medicated and non-medicated samples and in longitudinal studies ...
  • Murru, A.; Torra, M.; Callari, A.; Pacchiarotti, I.; Romero, S.; Gonzalez de la Presa, B.; Varo, C.; Goikolea, J.M.; Pérez Solá, Victor; Vieta, Eduard; Colom, F. (Elsevier, 2017)
    Lithium (Li) and valproate (VPA) are used in the treatment of bipolar disorder (BD), with narrow therapeutic window requiring periodic control of serum levels. This prevents intoxication, lack of efficacy due to low serum ...
  • Iglesias, Alba; Cimadevila, Marta; de la Fuente, Rocío Ailim; Martí Solano, Maria; Cadavid, María Isabel; Castro, Marián; Selent, Jana; Loza, María I.; Brea, José (Elsevier, 2017)
    The serotonin 2A (5-HT2A) receptor is a G-protein coupled receptor (GPCR) with a conserved disulfide bridge formed by Cys148 (transmembrane helix 3, TM3) and Cys227 (extracellular loop 2, ECL-2). We hypothesized that ...
  • Paun, Bruno; Bijnens, Bart; Iles, Tinen; Iaizzo, Paul A.; Butakoff, Constantine (Elsevier, 2017)
    Reparameterization of surfaces is a widely used tool in computer graphics known mostly from the remeshing algorithms. Recently, the surface reparameterization techniques started to gain popularity in the field of medical ...