Welcome to the UPF Digital Repository

Documents OpenAIRE (Open Access Infrastructure for Research in Europe)

Documents OpenAIRE (Open Access Infrastructure for Research in Europe)

 

Publicacions finançades pel Framework Programme 7 o l'European Research Council de la Unió Europea en el marc del Projecte OpenAIRE (Open Access Infraestructure for Research in Europe) que promou l'accés obert a Europa.

Recent Submissions

  • Fontseré Alemany, Clàudia, 1992-; Alvarez-Estape, Marina; Kuhlwilm, Martin; Marquès i Bonet, Tomàs, 1975-; Lizano González, Esther, 1974- (Wiley, 2021)
    Noninvasive samples as a source of DNA are gaining interest in genomic studies of endangered species. However, their complex nature and low endogenous DNA content hamper the recovery of good quality data. Target capture ...
  • Welker, Frido; Chiva, Cristina; Kuhlwilm, Martin; Manuel Montero, Marc de, 1991-; Gelabert Xirinachs, Pere, 1991-; Marquès i Bonet, Tomàs, 1975-; Sabidó Aguadé, Eduard, 1981-; Lalueza Fox, Carles, 1965-; Cappellini, Enrico (Nature Research, 2020)
    The phylogenetic relationships between hominins of the Early Pleistocene epoch in Eurasia, such as Homo antecessor, and hominins that appear later in the fossil record during the Middle Pleistocene epoch, such as Homo ...
  • Kumar, Shashwat (Elsevier, 2020)
    The aim of this study is to explore variations in the influence of Independent Regulatory Agencies (IRAs) in regulatory arrangements beyond functional explanations, focusing on six sectors in India. This article maps ...
  • Leuffen, Dirk; Schuessler, Julian; Gómez Díaz, Jana (Taylor & Francis, 2020)
    Research on differentiated integration (DI) in the European Union has burgeoned in recent years. However, we still know little about citizens’ attitudes towards the phenomenon. In this article, we argue that at the level ...
  • Fábrega, María José; Knödlseder, Nastassia; Nevot, Guillermo; Sanvicente, Marta; Toloza, Lorena; Santos-Moreno, Javier; Güell Cargol, Marc (American Chemical Society (ACS), 2021)
    In the past few years, new bacterial-cell-free transcription-translation systems have emerged as potent and quick platforms for protein production as well as for prototyping of DNA regulatory elements, genetic circuits, ...
  • Varela-Rial, Alejandro; Maryanow, Iain; Majewski, Maciej; Doerr, Stefan, 1987-; Schapin, Nikolai; Jiménez Luna, José, 1993-; De Fabritiis, Gianni (American Chemical Society (ACS), 2022)
    Deep learning has been successfully applied to structure-based protein-ligand affinity prediction, yet the black box nature of these models raises some questions. In a previous study, we presented KDEEP, a convolutional ...
  • Mendonça, Diogo A.; Bakker, Mariët; Cruz-Oliveira, Christine; Neves, Vera; Jiménez, Maria Angeles; Defaus, Sira; Cavaco, Marco; Salomé Veiga, Ana; Cadima-Couto, Iris; Castanho, Miguel A.R.B.; Andreu Martínez, David; Todorovski, Toni (American Chemical Society (ACS), 2021)
    Passing through the blood-brain barrier (BBB) to treat neurological conditions is one of the main hurdles in modern medicine. Many drugs with promising in vitro profiles become ineffective in vivo due to BBB restrictive ...
  • Doerr, Stefan, 1987-; Majewski, Maciej; Pérez, Adrià; Krämer, Andreas; Clementi, Cecilia; Noé, Frank; Giorgino, Toni; De Fabritiis, Gianni (American Chemical Society (ACS), 2021)
    Molecular dynamics simulations provide a mechanistic description of molecules by relying on empirical potentials. The quality and transferability of such potentials can be improved leveraging data-driven models derived ...
  • Milà Alomà, Marta; Brinkmalm, Ann; Ashton, Nicholas J.; Kvartsberg, Hlin; Shekari, Mahnaz; Operto, Grégory; Salvadó, Gemma; Falcon, Carles; Domingo Gispert, Juan; Vilor Tejedor, Natàlia, 1988-; Arenaza Urquijo, Eider M.; Grau-Rivera, Oriol; Sala Vila, Aleix; Sanchez-Benavides, Gonzalo; González de Echávarri, José Maria; Minguillón, Carolina; Fauria, Karine; Niñerola-Baizán, Aida; Perissinotti, Andrés; Kollmorgen, Gwendlyn; Suridjan, Ivonne; Zetterberg, Henrik; Molinuevo, José Luis; Blennow, Kaj; Suárez-Calvet, Marc; ALFA Study (Lippincott Williams & Wilkins, 2021)
    Background and objectives: To determine whether CSF synaptic biomarkers are altered in the early preclinical stage of the Alzheimer continuum and associated with Alzheimer disease (AD) risk factors, primary pathology, and ...
  • Garrido, Victoria; Piñero-Lambea, Carlos; Rodriguez-Arce, Irene; Paetzold, Bernhard, 1981-; Ferrar, Tony; Weber, Marc; Garcia Ramallo, Eva; Gallo López, Carolina, 1984-; Collantes, María; Peñuelas, Iván; Serrano Pubull, Luis, 1982-; Grilló, María-Jesús; Lluch-Senar, Maria 1982- (Wiley Open Access, 2021)
    Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome-reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm-associated bacterial ...
  • Kubiak-Szymendera, Monika; Pryszcz, Leszek Piotr, 1985-; Biatas, Wojciech; Celinska, Ewelina (MDPI, 2021)
    DNA methylation is a common, but not universal, epigenetic modification that plays an important role in multiple cellular processes. While definitely settled for numerous plant, mammalian, and bacterial species, the genome ...
  • Asthana, Jayant; Cade, Nicholas Ian; Normanno, Davide; Lim, Wei Ming; Surrey, Thomas (Life Science Alliance, 2021)
    During mitosis, the spindle undergoes morphological and dynamic changes. It reorganizes at the onset of the anaphase when the antiparallel bundler PRC1 accumulates and recruits central spindle proteins to the midzone. ...
  • Dios Martínez, Toni de, 1994-; Carrión, Pablo; Olalde Marquínez, Íñigo, 1987-; Llovera Nadal, Laia; Lizano González, Esther, 1974-; Pàmies, Dídac; Marquès i Bonet, Tomàs, 1975-; Balloux, François; van Dorp, Lucy; Lalueza Fox, Carles, 1965- (Elsevier, 2021)
    Ancient pathogen genomics is an emerging field allowing reconstruction of past epidemics. The demise of post-contact American populations may, at least in part, have been caused by paratyphoid fever brought by Europeans. ...
  • Burgos, Raul; Weber, Marc; Gallo López, Carolina, 1984-; Lluch-Senar, Maria 1982-; Serrano Pubull, Luis, 1982- (Elsevier, 2021)
    Trans-translation is a ubiquitous bacterial mechanism of ribosome rescue mediated by a transfer-messenger RNA (tmRNA) that adds a degradation tag to the truncated nascent polypeptide. Here, we characterize this quality ...
  • Nieto, Paula; Elosua-Bayés, Marc; Trincado Alonso, Juan Luis, 1987-; Marchese, Domenica, 1986-; Massoni-Badosa, Ramon; Nieto, Juan C.; Aguilar-Fernández, Sergio; Mereu, Elisabetta; Moutinho, Catia; Ruiz, Sara; Lorden, Patricia; Gut, Ivo Glynne; Heyn, Holger (Cold Spring Harbor Laboratory Press (CSHL Press), 2021)
    The tumor immune microenvironment is a main contributor to cancer progression and a promising therapeutic target for oncology. However, immune microenvironments vary profoundly between patients, and biomarkers for prognosis ...
  • Ramírez López, Angela; Pastor, Antonio; Torre Fornell, Rafael de la; La Porta, Carmen, 1985-; Ozaita Mintegui, Andrés, 1969-; Cabañero Ferri, David; Maldonado, Rafael, 1961- (Wiley, 2021)
    Background: Neuropathic pain is a complex condition characterized by sensory, cognitive and affective symptoms that magnify the perception of pain. The underlying pathogenic mechanisms are largely unknown and there is an ...
  • Rovira Clusellas, Meritxell; Atla, Goutham; Maestro, Miguel Ángel; Grau, Vanessa; García-Hurtado, Javier; Maqueda, Maria; Mosquera, Jose Luis; Yamada, Yasuhiro; Kerr-Conte, Julie; Pattou, Francois; Ferrer, Jorge (Cold Spring Harbor Laboratory Press (CSHL Press), 2021)
    Multiple transcription factors have been shown to promote pancreatic β-cell differentiation, yet much less is known about negative regulators. Earlier epigenomic studies suggested that the transcriptional repressor REST ...
  • Papadopoulou, Eleni, 1985-; Basagaña Flores, Xavier; Casas Sanahuja, Maribel; Fossati, Serena; Maitre, Léa; Sabidó Aguadé, Eduard, 1981-; Borràs, Eva; Urquiza, José M.; Vrijheid, Martine; Chatzi, Leda (Elsevier, 2021)
    Developing children are particularly vulnerable to the effects of exposure to per- and polyfluoroalkyl substances (PFAS), a group of endocrine disrupting chemicals. We hypothesized that early life exposure to PFASs is ...
  • Malinova, Antonia; Veghini, Lisa; Real, Francisco X.; Corbo, Vincenzo (Frontiers, 2021)
    Infidelity to cell fate occurs when differentiated cells lose their original identity and either revert to a more multipotent state or transdifferentiate into a different cell type, either within the same embryonic lineage ...
  • Saggion, Horacio; Shterionov, Dimitar; Labaka, Gorka; Van de Cruys, Tim; Vandeghinste, Vincent; Blat, Josep (CEUR Workshop Proceedings, 2021)
    This article presents an overview of the SignON European project which aims to develop technology for automatic translation between sign and oral languages (and vice-versa). In order to achieve this objective, the project ...

View more