• Topoisomeric membrane-active peptides: A review of the last two decades

  Carrera-Aubesart, Adam; Gallo, María, 1989-; Defaus, Sira; Todorovski, Toni; Andreu Martínez, David (MDPI, 2023)

  In recent decades, bioactive peptides have been gaining recognition in various biomedical areas, such as intracellular drug delivery (cell-penetrating peptides, CPPs) or anti-infective action (antimicrobial peptides, AMPs), ...
• Exploring the influence of circulating endocannabinoids and nucleus accumbens functional connectivity on anorexia nervosa severity

  Miranda-Olivos, Romina; Baenas, Isabel; Steward, Trevor; Granero, Roser; Pastor, Antonio; Sánchez, Isabel; Juaneda-Seguí, Asier; Pino-Gutiérrez, Amparo del; Fernández-Formoso, José A.; Vilarrasa, Nuria; Guerrero-Pérez, Fernando; Virgili, Núria; López-Urdiales, Rafael; Jiménez Murcia, Susana; Torre Fornell, Rafael de la; Soriano Mas, Carles; Fernández Aranda, Fernando (Nature Research, 2023)

  Anorexia nervosa (AN) is a severe psychiatric disorder characterized by a harmful persistence of self-imposed starvation resulting in significant weight loss. Research suggests that alterations in the nucleus accumbens ...
• A new assemblage of late Neanderthal remains from Cova Simanya (NE Iberia)

  Morales, Juan I.; Cebrià, Artur; Soto, María; Rodríguez-Hidalgo, Antonio; Hernando, Raquel; Moreno-Ribas, Elena; Lombao, Diego; Rabuñal, José R.; Martín-Perea, David M.; García-Tabernero, Antonio; Allué, Ethel; García Basanta, Andrea; Lizano González, Esther, 1974-; Marquès i Bonet, Tomàs, 1975-; Talamo, Sahra; Tassoni, Laura; Lalueza Fox, Carles, 1965-; Fullola, Josep M.; Rosas, Antonio (Frontiers, 2023)

  This study presents an exceptional collection of 54 Late Pleistocene human remains that correspond to at least three Neanderthal individuals from Simanya Gran, the main gallery of Cova Simanya, located in the northeastern ...
• A quantitative systems pharmacology model for certolizumab pegol treatment in moderate-to-severe psoriasis

  Coto-Segura, Pablo; Segú-Vergés, Cristina; Martorell, Antonio; Moreno-Ramírez, David; Jorba Argemí, Guillem; Junet, Valentin; Guerri, Filippo; Daura, Xavier; Oliva Miguel, Baldomero; Cara, Carlos; Suárez-Magdalena, Olaya; Abraham, Sonya; Mas, José Manuel (Frontiers, 2023)

  Background: Psoriasis is a chronic immune-mediated inflammatory systemic disease with skin manifestations characterized by erythematous, scaly, itchy and/or painful plaques resulting from hyperproliferation of keratinocytes. ...
• Approaching unsafe limits: climate-related health inequities within and beyond Europe

  Daalen, Kim van; Tonne, Cathryn; Borrell i Thió, Carme; Nilsson, Maria; Lowe, Rachel (Elsevier, 2023)
• Spatial and sector-specific contributions of emissions to ambient air pollution and mortality in European cities: a health impact assessment

  Khomenko, Sasha; Pisoni, Enrico; Thunis, Philippe; Bessagnet, Bertrand; Cirach, Marta; Iungman, Tamara; Pereira Barboza, Evelise; Khreis, Haneen; Mueller, Natalie, 1988-; Tonne, Cathryn; Hoogh, Kees de; Hoek, Gerard; Chowdhury, Sourangsu; Lelieveld, Jos; Nieuwenhuijsen, Mark J. (Elsevier, 2023)

  Background: Ambient air pollution is a major risk to health and wellbeing in European cities. We aimed to estimate spatial and sector-specific contributions of emissions to ambient air pollution and evaluate the effects ...
• Health benefits of Open Streets programmes in Latin America: a quantitative health impact assessment

  Velázquez-Cortés, Daniel; Nieuwenhuijsen, Mark J.; Jerrett, Michael; Rojas Rueda, David, 1979- (Elsevier, 2023)

  Background: To improve physical activity in Latin American cities, several interventions have been promoted, such as Open Streets programmes. Our study aims to quantify the health and economic effects of Open Streets-related ...
• Understanding the stakeholders’ intention to use economic decision-support tools: a cross-sectional study with the tobacco return on investment tool

  Cheung, Kei Long; Evers, Silvia M. A. A.; Hiligsmann, Mickaël; Vokó, Zoltán; Pokhrel, Subhash; Jones, Teresa; Muñoz, Celia; Wolfenstetter, Silke B.; Józwiak-Hagymásy, Judit; de Vries, Hein (Elsevier, 2016)

  Background. Despite an increased number of economic evaluations of tobacco control interventions, the uptake by stakeholders continues to be limited. Understanding the underlying mechanism in adopting such economic ...
• Urinary metabolomic profile of youth at risk of chronic kidney disease in Nicaragua

  Hall, Samantha M.; Raines, Nathan H.; Ramirez Rubio, Oriana; Amador, Juan José; López-Pilarte, Damaris; O'Callaghan-Gordo, Cristina; Gil-Redondo, Rubén; Embade, Nieves; Millet, Oscar; Peng, Xiaojing; Vences, Selene; Keogh, Sinead A.; Delgado, Iris; Friedman, David J.; Brooks, Daniel R.; Leibler, Jessica H. (Wolters Kluwer (LWW), 2023)

  Background: CKD of a nontraditional etiology (CKDnt) is responsible for high mortality in Central America, although its causes remain unclear. Evidence of kidney dysfunction has been observed among youth, suggesting that ...
• No taxation without informational foundation: on the role of legibility in tax state development

  Vom Hau, Matthias; Peres-Cajías, José Alejandro; Soifer, Hillel David (Cambridge University Press, 2023)

  This article combines cross-national statistical analysis and in-depth historical case studies of Argentina and Chile to explore the relationship between two crucial dimensions of state capacity. We show that information ...
• Firefighters and the liver: Exposure to PFAS and PAHs in relation to liver function and serum lipids (CELSPAC-FIREexpo study)

  Pálešová, Nina; Maitre, Léa; Stratakis, Nikos; Řiháčková, Katarína; Pindur, Aleš; Kohoutek, Jir̂í; Šenk, Petr; Bartošková Polcrová, Anna; Gregor, Petr; Vrijheid, Martine; Čupr, Pavel (Elsevier, 2023)

  Introduction: Firefighting is one of the most hazardous occupations due to exposure to per- and polyfluoroalkyl substances (PFAS) and polycyclic aromatic hydrocarbons (PAHs). Such exposure is suspected to affect the ...
• Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts

  Casas Sanahuja, Maribel; Martínez, David; Kogevinas, Manolis; García, Ana María; Nieuwenhuijsen, Mark J.; Vrijheid, Martine (NOROSH, 2015)

  Objectives. We assessed whether maternal employment during pregnancy – overall and in selected occupational sectors – is associated with birth weight, small for gestational age (SGA), term low birth weight (LBW), length ...
• Automatic identification of informative regions with epigenomic changes associated to hematopoiesis

  Carrillo-de-Santa Pau, Enrique; Juan, David; Pancaldi, Vera; Were, Felipe; Martin-Subero, José Ignacio; Rico, Daniel; Valencia, Alfonso; BLUEPRINT Consortium (Oxford University Press, 2017)

  Hematopoiesis is one of the best characterized biological systems but the connection between chromatin changes and lineage differentiation is not yet well understood. We have developed a bioinformatic workflow to generate ...
• Natural outdoor environments and mental health: stress as a possible mechanism

  Triguero Mas, Margarita, 1985-; Donaire González, David; Valentín, Antònia; Martínez, David; Carrasco Turigas, Glòria; Ambrós, Albert; Martínez-Íñiguez, Tania; Cirach, Marta; Cirac-Claveras, Judith; Nieuwenhuijsen, Mark J. (Elsevier, 2017)

  Introduction: Better mental health has been associated with exposure to natural outdoor environments (NOE). However, comprehensive studies including several indicators of exposure and outcomes, potential effect modifiers ...
• The acute effects of ultraviolet radiation on the blood transcriptome are independent

  Bustamante Pineda, Mariona; Hernandez-Ferrer, Carles, 1987-; Sarria-Trujillo, Yaris; Harrison, Graham I.; Nonell Mazelón, Lara; Kang, Wenjing; Friedländer, Marc R.; Estivill, Xavier, 1955-; González, Juan Ramón; Nieuwenhuijsen, Mark J.; Young, Antony R. (Elsevier, 2017)

  The molecular basis of many health outcomes attributed to solar ultraviolet radiation (UVR) is unknown. We tested the hypothesis that they may originate from transcriptional changes in blood cells. This was determined by ...
• Early life tobacco exposure and children's telomere length: The HELIX project

  Osorio Yáñez, Citlalli; Clemente Batalha Pardal, Diana, 1990-; Maitre, Léa; Vives Usano, Marta, 1990-; Bustamante Pineda, Mariona; Martínez, David; Casas Sanahuja, Maribel; Urquiza, José M.; Tamayo-Uria, Ibon; Sunyer Deu, Jordi; Vrijheid, Martine (Elsevier, 2020)

  Telomere length and mitochondrial DNA content are considered biomarkers of cellular aging, oxidative stress, and inflammation, but there is almost no information on their association with tobacco smoke exposure in fetal ...
• Interaction between airborne copper exposure and ATP7B polymorphisms on inattentiveness in scholar children

  Alemany, Silvia; Vilor-Tejedor, Natàlia; Bustamante Pineda, Mariona; Álvarez Pedrerol, Mar, 1981-; Rivas, Ioar; Forns i Guzman, Joan, 1981-; Querol, Xavier; Pujol Martí, Jesús, 1981-; Sunyer Deu, Jordi (Elsevier, 2017)

  Recent research indicates that airborne copper exposure in scholar children negatively affects brain functioning. These effects are likely to be influenced by the efficiency of copper metabolism, which is partly regulated ...
• Cortical structures associated with sports participation in children: a population-based study

  López Vicente, Mònica, 1988-; Tiemeier, Henning; Wildeboer, Andrea; Muetzel, Ryan L.; Verhulst, Frank C.; Jaddoe, Vincent W.V.; Sunyer Deu, Jordi; White, Tonya (Taylor & Francis, 2017)

  We studied cortical morphology in relation to sports participation and type of sport using a large sample of healthy children (n = 911). Sports participation data was collected through a parent-reported questionnaire. ...
• Value of shared preclinical safety studies – The eTOX database

  Briggs, Katharine; Barber, Chris; Cases, Montserrat; Marc, Philippe; Steger-Hartmann, Thomas (Elsevier, 2015)

  A first analysis of a database of shared preclinical safety data for 1214 small molecule drugs and drug candidates extracted from 3970 reports donated by thirteen pharmaceutical companies for the eTOX project (www.etoxproject.eu) ...
• Rethinking the effects of financial globalization

  Broner, Fernando; Ventura, Jaume (Oxford University Press, 2016)

  During the past three decades, many countries have lifted restrictions on cross-border financial transactions. We present a simple model that can account for the observed effects of financial globalization. The model ...

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