• Detection of differential bait proteoforms through immunoprecipitation-mass spectrometry data analysis

  Kourtis, Savvas; Cianferoni, Damiano; Serrano Pubull, Luis, 1982-; Sdelci, Sara (Nature Research, 2024)

  Proteins are often referred to as the workhorses of cells, and their interactions are necessary to facilitate specific cellular functions. Despite the recognition that protein-protein interactions, and thus protein functions, ...
• Deconwolf enables high-performance deconvolution of widefield fluorescence microscopy images

  Wernersson, Erik; Gelali, Eleni; Girelli, Gabriele; Wang, Su; Castillo, David; Mattsson Langseth, Christoffer; Verron, Quentin; Nguyen, Huy Q.; Chattoraj, Shyamtanu; Martinez Casals, Anna; Blom, Hans; Lundberg, Emma; Nilsson, Mats; Martí Renom, Marc A.; Wu, Chao-Ting; Crosetto, Nicola; Bienko, Magda (Nature Research, 2024)

  Microscopy-based spatially resolved omic methods are transforming the life sciences. However, these methods rely on high numerical aperture objectives and cannot resolve crowded molecular targets, limiting the amount of ...
• “We are protectors, not protestors”: global impacts of extractivism on human–nature bonds

  Hanaček, Ksenija; Tran, Dalena; Landau, Arielle; Sanz, Teresa; Thiri, May Aye; Navas, Grettel; Del Bene, Daniela; Liu, Juan; Walter, Mariana; Lopez, Aida; Roy, Brototi; Fanari, Eleonora; Martinez-Alier, Joan (Springer, 2024)

  This article analyzes the global impacts of extractivism on human–nature bonds. To do so, we rely on socio-ecological confict data from the Global Atlas of Environmental Justice. Over 1800 cases involving resistance to the ...
• Documenting the de-identification process of clinical and imaging data for AI for health imaging projects

  Kondylakis, Haridimos; Garcia Lezena, Teresa; Tsiknakis, Manolis (Springer, 2024)

  Artificial intelligence (AI) is revolutionizing the field of medical imaging, holding the potential to shift medicine from a reactive "sick-care" approach to a proactive focus on healthcare and prevention. The successful ...
• Individualization and collectivization in contexts of organized criminal violence: the case of Mexico’s War on organized crime

  Kalmanovitz, Pablo; Bradley, Miriam (Oxford University Press, 2023)

  Most lethal violence now occurs outside of war zones. In Latin America, countries like Brazil, Mexico, El Salvador, and Colombia have often had yearly homicide rates far exceeding those in Afghanistan or Syria. The use of ...
• The Wnt-dependent master regulator NKX1-2 controls mouse pre-implantation development

  Nakagawa, Shoma; Carnevali, Davide; Tan, Xiangtian; Alvarez, Mariano J.; Parfitt, David-Emlyn; Di Vicino, Umberto; Arumugam, Karthik; Shin, William; Aranda, Sergi; Normanno, Davide; Sebastián Pérez, Rubén; Cannatá, Chiara; Cortes, Paola; Neguembor, Maria Victoria; Shen, Michael M.; Califano, Andrea; Cosma, Maria Pia (Elsevier, 2024)

  Embryo size, specification, and homeostasis are regulated by a complex gene regulatory and signaling network. Here we used gene expression signatures of Wnt-activated mouse embryonic stem cell (mESC) clones to reverse ...
• TANGO1 inhibitors reduce collagen secretion and limit tissue scarring

  Raote, Ishier; Häkkinen, Hanna-Maria; Vibe, Carine; Broadbent, Katrina; Carolis, Carlo; Ruprecht, Verena; Malhotra, Vivek (Nature Research, 2024)

  Uncontrolled secretion of ECM proteins, such as collagen, can lead to excessive scarring and fibrosis and compromise tissue function. Despite the widespread occurrence of fibrotic diseases and scarring, effective therapies ...
• Active transcription and epigenetic reactions synergistically regulate meso-scale genomic organization

  Kant, Aayush; Guo, Zixian; Vinayak, Vinayak; Neguembor, Maria Victoria; Li, Wing Shun; Agrawal, Vasundhara; Pujadas, Emily; Almassalha, Luay; Backman, Vadim; Lakadamyali, Melike; Cosma, Maria Pia; Shenoy, Vivek B. (Nature Research, 2024)

  In interphase nuclei, chromatin forms dense domains of characteristic sizes, but the influence of transcription and histone modifications on domain size is not understood. We present a theoretical model exploring this ...
• Engineering Mycoplasma pneumoniae to bypass the association with Guillain-Barré syndrome

  Broto, Alicia; Piñero-Lambea, Carlos; Segura-Morales, Carolina; Tio-Gillen, Anne P.; Unger, Wendy W. J.; Burgos, Raul; Mazzolini, Rocco; Miravet Verde, Samuel; Jacobs, Bart C.; Casas, Josefina; Huizinga, Ruth; Lluch-Senar, Maria 1982-; Serrano Pubull, Luis, 1982- (Elsevier, 2024)

  A non-pathogenic Mycoplasma pneumoniae-based chassis is leading the development of live biotherapeutic products (LBPs) for respiratory diseases. However, reports connecting Guillain-Barré syndrome (GBS) cases to prior M. ...
• Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony

  Eder, Matthias; Martin, Olivier M. F.; Oswal, Natasha; Sedlackova, Lucia; Moutinho, Catia; Carmen Fabregat, Andrea del; Menéndez Bravo, Simón; Sebé-Pedrós, Arnau; Heyn, Holger; Stroustrup, Nicholas (Elsevier, 2024)

  In aging, physiologic networks decline in function at rates that differ between individuals, producing a wide distribution of lifespan. Though 70% of human lifespan variance remains unexplained by heritable factors, little ...
• Characterization of the common genetic variation in the spanish population of Navarre

  Maillo, Alberto; Beltran, Sergi; Gómez Cabrero, David (MDPI, 2024)

  Large-scale genomic studies have significantly increased our knowledge of genetic variability across populations. Regional genetic profiling is essential for distinguishing common benign variants from disease-causing ones. ...
• Childhood exposure to outdoor air pollution in different microenvironments and cognitive and fine motor function in children from six European cohorts

  Domínguez, Alan; Koch, Sarah; Márquez, Sandra; Castro, Montserrat de; Urquiza, José M.; Evandt, Jorunn; Oftedal, Bente; Aasvang, Gunn Marit; Kampouri, Mariza; Vafeiadi, Marina, 1983-; Mon-Williams, Mark; Lewer, Dan; Lepeule, Johanna; Andrušaitytė, Sandra; Vrijheid, Martine; Guxens Junyent, Mònica; Nieuwenhuijsen, Mark J. (Elsevier, 2024)

  Background: Exposure to air pollution during childhood has been linked with adverse effects on cognitive development and motor function. However, limited research has been done on the associations of air pollution exposure ...
• Urban green spaces and behavioral and cognitive development in children: a health impact assessment of the Barcelona "Eixos Verds" Plan (Green Axis Plan)

  Opbroek, Jet; Pereira Barboza, Evelise; Nieuwenhuijsen, Mark J.; Dadvand, Payam; Mueller, Natalie, 1988- (Elsevier, 2024)

  Background: Urban environments lack natural features, while nature exposure in cities has been associated with health benefits, including children's neurodevelopment. Through extensive street greening, Barcelona's Eixos ...
• Cohort Profile: Barcelona Life Study Cohort (BiSC)

  Dadvand, Payam; Gascon Merlos, Mireia, 1984-; Bustamante Pineda, Mariona; Rivas, Ioar; Foraster Pulido, Maria, 1984-; Basagaña Flores, Xavier; Cosín Tomàs, Marta; Ferrer Vergés, Muriel; Gómez Herrera, Laura C.; Jiménez Arenas, Pol; Júlvez Calvo, Jordi; Morillas, Àlex; Nieuwenhuijsen, Mark J.; Persavento, Cecilia; Pujol, Jesús; Vrijheid, Martine; Sunyer Deu, Jordi; BiSC Group (Oxford University Press, 2024)
• Physical activity and body mass related to catch-up lung function growth in childhood: a population-based accelerated cohort study

  Koch, Sarah; Prado Peralta, María Gabriela; Carsin, Anne-Elie; Abellan, Alicia; Roda, Célina; Torrent, Maties; Iñiguez, Carmen; Ballester Díez, Ferran; Ferrero, Amparo; Zabaleta, Carlos; Lertxundi, Aitana; Guxens Junyent, Mònica; Vrijheid, Martine; Sunyer Deu, Jordi; Casas Sanahuja, Maribel; García Aymerich, Judith (BMJ Publishing Group, 2024)

  Objective: The existence of catch-up lung function growth and its predictors is uncertain. We aimed to identify lung function trajectories and their predictors in a population-based birth cohort. Methods: We applied ...
• The impact of thin and thick truth: the limits of truth commission design in polarized societies

  Daniels, Lesley-Ann; Zalunardo, Virginia (Taylor & Francis, 2024)

  Dealing with the legacy of the past has become a popular demand in postconflict and posttransition countries. However, the pursuit of truth can be a divisive issue that threatens rather than promotes understanding, ...
• New interventionism: the re-politicisation of electricity governance with renewable energy policies in the UK, Mexico and Morocco

  Mathieu, Emmanuelle; Valenzuela, Jose Maria (Taylor & Francis, 2024)

  While the 1990s saw the retreat of governments from economic governance to the benefit of the market and independent regulatory agencies, we now observe a comeback of governments’ interventions in the economy. This recent ...
• Trust, mistrust and distrust as blind spots of Social Licence to Operate: illustration via three forerunner countries in nuclear waste management

  Lehtonen, Markku; Kojo, Matti; Kari, Mika; Jartti, Tuija; Litmanen, Tapio (Taylor & Francis, 2022)

  The notion of social licence to operate (SLO) has become a widely applied concept for companies in mining and resource extraction industries to manage their social and community relations, in the face of local criticism ...
• Person marking in Catalan Sign Language (LSC) personal pronouns

  Veiga Busto, Raquel (Universitat Pompeu Fabra. Servicio de Publicaciones, 2020)

  This paper addresses the question of whether the person category is grammaticalized insign language personal pronouns. Building on Berenz’s (1996) Body Coordinates Model,I argue that Catalan Sign Language (LSC) encodes the ...
• Dissecting gene activation and chromatin remodeling dynamics in single human cells undergoing reprogramming

  Martínez Sarmiento, José A.; Cosma, Maria Pia; Lakadamyali, Melike (Elsevier, 2024)

  During cell fate transitions, cells remodel their transcriptome, chromatin, and epigenome; however, it has been difficult to determine the temporal dynamics and cause-effect relationship between these changes at the ...

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