Welcome to the UPF Digital Repository

Documents OpenAIRE (Open Access Infrastructure for Research in Europe)

Documents OpenAIRE (Open Access Infrastructure for Research in Europe)

 

Publicacions finançades pel Framework Programme 7 o l'European Research Council de la Unió Europea en el marc del Projecte OpenAIRE (Open Access Infraestructure for Research in Europe) que promou l'accés obert a Europa.

Recent Submissions

  • Carrignon, Simon, 1987-; Bentley, R. Alexander; Ruck, Damia (Nature Research, 2019)
    As social media technologies alter the variation, transmission and sorting of online information, short-term cultural evolution is transformed. In these media contexts, cultural evolution is an intra-generational process ...
  • Chandra, Vikash; Ibrahim, Hazem; Halliez, Clémentine; Prasad, Rashmi B.; Vecchio, Federica; Dwivedi, Om Prakash; Kvist, Jouni; Balboa, Diego; Saarimäki-Vire, Jonna; Montaser, Hossam; Barsby, Tom; Lithovius, Väinö; Artner, Isabella; Gopalakrishnan, Swetha; Groop, Leif; Mallone, Roberto; Eizirik, Décio L.; Otonkoski, Timo (Nature Research, 2022)
    Type 1 diabetes (T1D) is an autoimmune disease that results in the destruction of insulin producing pancreatic β-cells. One of the genes associated with T1D is TYK2, which encodes a Janus kinase with critical roles in ...
  • Zadra, Ivan, 1991-; Jiménez-Delgado, Senda; Anglada-Girotto, Miquel; Segura-Morales, Carolina; Compton, Zachary J.; Janke, Carsten; Serrano Pubull, Luis, 1982-; Ruprecht, Verena; Vernos, Isabelle, 1959- (Nature Research, 2022)
    Regulation of microtubule (MT) dynamics is key for mitotic spindle assembly and faithful chromosome segregation. Here we show that polyglutamylation, a still understudied post-translational modification of spindle MTs, is ...
  • Seuma, Mireia; Lehner, Ben, 1978-; Bolognesi, Benedetta (Nature Research, 2022)
    Multiplexed assays of variant effects (MAVEs) guide clinical variant interpretation and reveal disease mechanisms. To date, MAVEs have focussed on a single mutation type-amino acid (AA) substitutions-despite the diversity ...
  • Escobedo, Albert; Piccirillo, Jonathan; Aranda, Juan; Diercks, Tammo; Mateos, Borja; Garcia-Cabau, Carla; Sánchez-Navarro, Macarena; Topal, Busra; Biesaga, Mateusz; Staby, Lasse; Kragelund, Birthe B.; García, Jesús; Millet, Oscar; Orozco, Modesto; Coles, Murray; Crehuet, Ramon; Salvatella, Xavier (Nature Research, 2022)
    The binding of intrinsically disordered proteins to globular ones can require the folding of motifs into α-helices. These interactions offer opportunities for therapeutic intervention but their modulation with small molecules ...
  • Ostrander, Elaine A.; Wang, Guo-Dong; Larson, Greger; vonHoldt, Bridgett M.; Davis, Brian W.; Jagannathan, Vidhya; Hitte, Christophe; Wayne, Robert K.; Zhang, Ya-Ping; Dog10K Consortium (Oxford University Press, 2019)
    Dogs are the most phenotypically diverse mammalian species, and they possess more known heritable disorders than any other non-human mammal. Efforts to catalog and characterize genetic variation across well-chosen populations ...
  • Dyballa, Sylvia, 1982-; Miñana, Rafael; Rubio-Brotons, Maria; Cornet Bartolomé, Carles, 1991-; Pederzani, Tiziana; Escaramis, Geòrgia; Garcia-Serna, Ricard; Mestres i López, Jordi; Terriente, Javier (Oxford University Press, 2019)
    Cardiovascular drug toxicity is responsible for 17% of drug withdrawals in clinical phases, half of post-marketed drug withdrawals and remains an important adverse effect of several marketed drugs. Early assessment of ...
  • Zamora-López, Gorka; Brasselet, Romain (Nature Research, 2019)
    Among the many features of natural and man-made complex networks the small-world phenomenon is a relevant and popular one. But, how small is a small-world network and how does it compare to others? Despite its importance, ...
  • Herreros Alonso, Ivan; Miquel, Laia; Blithikioti, Chrysanthi; Nuño, Laura; Rubio Ballester, Belén; Grechuta, Klaudia; Gual, Antoni; Balcells-Oliveró, Mercè; Verschure, Paul F. M. J. (MDPI, 2019)
    Background—The cerebellum has been recently suggested as an important player in the addiction brain circuit. Cannabis is one of the most used drugs worldwide, and its long-term effects on the central nervous system are not ...
  • Fontseré Alemany, Clàudia, 1992-; Kuhlwilm, Martin; Morcillo Suárez, Carlos, 1969-; Alvarez-Estape, Marina; Hecht, Jochen; Marquès i Bonet, Tomàs, 1975- (Elsevier, 2022)
    Knowledge on the population history of endangered species is critical for conservation, but whole-genome data on chimpanzees (Pan troglodytes) is geographically sparse. Here, we produced the first non-invasive geolocalized ...
  • Cuesta, Helena; Gómez Gutiérrez, Emilia, 1975- (Ubiquity Press, 2022)
    This paper deals with the automatic transcription of four-part, a cappella singing, audio performances. In particular, we exploit an existing, deep-learning based, multiple F0 estimation method and complement it with two ...
  • Shvets, Alexander; Wanner, Leo (MDPI, 2022)
    The speech of native speakers is full of idiosyncrasies. Especially prominent are lexically restricted binary word co-occurrences of the type high esteem, strong tea, run [an] experiment, war break(s) out, etc. In lexicography, ...
  • Butti, Silvia; Dalmau, Víctor (SpringerOpen, 2022)
    We study the complexity of the Distributed Constraint Satisfaction Problem (DCSP) on a synchronous, anonymous network from a theoretical standpoint. In this setting, variables and constraints are controlled by agents which ...
  • Butti, Silvia; Dalmau, Víctor (Dagstuhl Publishing, 2021)
    Given a pair of graphs 𝐀 and 𝐁, the problems of deciding whether there exists either a homomorphism or an isomorphism from 𝐀 to 𝐁 have received a lot of attention. While graph homomorphism is known to be NP-complete, ...
  • Brasó-Vives, Marina, 1990-; Marlétaz, Ferdinand; Echchiki, Amina; Mantica, Federica; Acemel, Rafael D.; Gómez Skarmeta, José Luis; Hartasánchez Frenk, Diego Andrés, 1982-; Le Targa, Lorlane; Pontarotti, Pierre; Tena, Juan J.; Maeso, Ignacio; Escriva, Hector; Irimia, Manuel; Robinson-Rechavi, Marc (BioMed Central, 2022)
    Background: Amphioxus are non-vertebrate chordates characterized by a slow morphological and molecular evolution. They share the basic chordate body-plan and genome organization with vertebrates but lack their 2R whole-genome ...
  • Oldoni, Emanuela; Saunders, Gary; Bietrix, Florence; Garcia Bermejo, Maria Laura; Niehues, Anna; Hoen, Peter A. C.; Nordlund, Jessica; Hajduch, Marian; Scherer, Andreas; Kivinen, Katja; Pitkänen, Esa; Mäkela, Tomi Pekka; Gut, Ivo Glynne; Scollen, Serena; Kozera, Łukasz; Esteller, Manel; Shi, Leming; Ussi, Anton; Andreu, Antonio L.; Gool, Alian J. van (Frontiers, 2022)
    Personalised medicine (PM) presents a great opportunity to improve the future of individualised healthcare. Recent advances in -omics technologies have led to unprecedented efforts characterising the biology and molecular ...
  • Graupera, Isabel; García-Retortillo, Montserrat; Ginès, Pere; LiverScreen Consortium Investigators (BioMed Central, 2022)
    Background: the development of liver cirrhosis is usually an asymptomatic process until late stages when complications occur. The potential reversibility of the disease is dependent on early diagnosis of liver fibrosis and ...
  • Stobbe, Miranda D.; González-Pérez, Abel; López Bigas, Núria; Gut, Ivo Glynne (Public Library of Science (PLoS), 2022)
  • Oswal, Natasha; Martin, Olivier M. F., 1991-; Stroustrup, Sofia; Bruckner, Monika Anna Matusiak; Stroustrup, Nicholas (Public Library of Science (PLoS), 2022)
    Aging involves a transition from youthful vigor to geriatric infirmity and death. Individuals who remain vigorous longer tend to live longer, and within isogenic populations of C. elegans the timing of age-associated ...
  • Cutler, Kevin J.; Stringer, Carsen; Lo, Teresa W.; Rappez, Luca; Stroustrup, Nicholas; Peterson, S. Brook; Wiggins, Paul A.; Mougous, Joseph D. (Nature Research, 2022)
    Advances in microscopy hold great promise for allowing quantitative and precise measurement of morphological and molecular phenomena at the single-cell level in bacteria; however, the potential of this approach is ultimately ...

View more