• Uncertainty assessment of proarrhythmia predictions derived from multi-level in silico models

  Kopańska, Karolina; Rodríguez-Belenguer, Pablo; Llopis-Lorente, Jordi; Trenor, Beatriz; Saiz, Javier; Pastor Maeso, Manuel (Springer, 2023)

  In silico methods can be used for an early assessment of arrhythmogenic properties of drug candidates. However, their use for decision-making is conditioned by the possibility to estimate the predictions' uncertainty. This ...
• Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study

  Ni, Jiaqi; Castañer, Olga; Sala Vila, Aleix; Torre Fornell, Rafael de la; Malcampo, Mireia; PREDIMED-Plus investigators (Elsevier, 2023)

  Background: Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited and inconsistent ...
• The FAIR Cookbook - the essential resource for and by FAIR doers

  Rocca-Serra, Philippe; FAIR Cookbook Contributors; Sansone, Susanna-Assunta (Nature Research, 2023)

  The notion that data should be Findable, Accessible, Interoperable and Reusable, according to the FAIR Principles, has become a global norm for good data stewardship and a prerequisite for reproducibility. Nowadays, FAIR ...
• Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart

  Milenkovic, Ivan; Santos Vieira, Helaine Graziele; Lucas, Morghan C.; Ruiz-Orera, Jorge; Patone, Giannino; Kesteven, Scott; Wu, Jianxin; Feneley, Michael; Espadas, Guadalupe; Sabidó Aguadé, Eduard, 1981-; Hübner, Norbert; van Heesch, Sebastiaan; Völkers, Mirko; Novoa, Eva Maria (Oxford University Press, 2023)

  The existence of naturally occurring ribosome heterogeneity is now a well-acknowledged phenomenon. However, whether this heterogeneity leads to functionally diverse 'specialized ribosomes' is still a controversial topic. ...
• Copy number variation on ABCC2-DNMBP loci affects the diversity and composition of the fecal microbiota in pigs

  Ramayo-Caldas, Yuliaxis; Crespo-Piazuelo, Daniel; Morata, Jordi; González-Rodríguez, Olga; Sebastià, Cristina; Castelló, Anna; Dalmau, Antoni; Ramos-Onsins, Sebastián; Alexiou, Konstantinos G.; Folch, Josep M.; Quintanilla, Raquel; Ballester Devís, Maria (American Society for Microbiology, 2023)

  Genetic variation in the pig genome partially modulates the composition of porcine gut microbial communities. Previous studies have been focused on the association between single nucleotide polymorphisms (SNPs) and the gut ...
• Beauveria bassiana rewires molecular mechanisms related to growth and defense in tomato

  Proietti, Silvia; Falconieri, Gaia Salvatore; Bertini, Laura; Pascale, Alberto; Bizzarri, Elisabetta; Morales Sanfrutos, Julia; Sabidó Aguadé, Eduard, 1981-; Ruocco, Michelina; Monti, Maurilia M.; Russo, Assunta; Dziurka, Kinga; Ceci, Marcello; Loreto, Francesco; Caruso, Carla (Oxford University Press, 2023)

  Plant roots can exploit beneficial associations with soil-inhabiting microbes, promoting growth and expanding the immune capacity of the host plant. In this work, we aimed to provide new information on changes occurring ...
• Electronic Cigarette Use in 12 European countries: results from the TackSHS survey

  Gallus, Silvano; Lugo, Alessandra; Stival, Chiara; Cerrai, Sonia; Clancy, Luke; Filippidis, Filippos T.; Gorini, Giuseppe; López, Maria José; López Nicolás, Ángel; Molinaro, Sabrina; Odone, Anna; Soriano, Joan B.; Tigova, Olena; van den Brandt, Piet A.; Vardavas, Constantine; Fernández, Esteve; TackSHS Project Investigators (Japan Epidemiological Association, 2023)

  Background: Limited data on electronic cigarette prevalence, patterns, and settings of use are available from several European countries. Methods: Within the TackSHS project, a face-to-face survey was conducted in 2017-2018 ...
• A high-throughput approach to predict A-to-I effects on RNA structure indicates a change of double-stranded content in noncoding RNAs

  Delli Ponti, Riccardo, 1987-; Broglia, Laura; Vandelli, Andrea; Armaos, Alexandros, 1989-; Torrent Burgas, Marc; Sanchez de Groot, Natalia; Tartaglia, Gian Gaetano (Wiley, 2023)

  RNA molecules undergo a number of chemical modifications whose effects can alter their structure and molecular interactions. Previous studies have shown that RNA editing can impact the formation of ribonucleoprotein complexes ...
• STereotactic Arrhythmia Radioablation (STAR): the standardized treatment and outcome platform for stereotactic therapy of re-entrant tachycardia by a multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe

  Grehn, Melanie; Algara López, Manuel-Ignacio; Martí-Almor, Julio; Verhoeff, Joost J. C. (Oxford University Press, 2023)

  The EU Horizon 2020 Framework-funded Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) consortium has been established as a large research ...
• Chromosome-level genome assembly of Lilford’s wall lizard, Podarcis lilfordi (Günther, 1874) from the Balearic Islands (Spain)

  Gómez-Garrido, Jèssica; Cruz, Fernando; Alioto, Tyler; Feiner, Nathalie; Uller, Tobias; Gut, Marta; Sanchez Escudero, Ignacio; Tavecchia, Giacomo; Rotger, Andreu; Otalora Acevedo, Katherin Eliana; Baldo, Laura (Oxford University Press, 2023)

  The Mediterranean lizard Podarcis lilfordi is an emblematic species of the Balearic Islands. The extensive phenotypic diversity among extant isolated populations makes the species a great insular model system for ...
• Y chromosome sequence and epigenomic reconstruction across human populations

  Esteller Cucala, Paula; Palmada-Flores, Marc; Kuderna, Lukas F.K.; Fontseré Alemany, Clàudia, 1992-; Serres Armero, Aitor, 1992-; Dabad, Marc; Torralvo, María; Faella, Armida; Ferrández Peral, Luis, 1991-; Llovera Nadal, Laia; Fornas Carreño, Oscar; Julià, Eva; Ramírez, Erika; González, Irene; Hecht, Jochen; Lizano González, Esther, 1974-; Juan, David; Marquès i Bonet, Tomàs, 1975- (Nature Research, 2023)

  Recent advances in long-read sequencing technologies have allowed the generation and curation of more complete genome assemblies, enabling the analysis of traditionally neglected chromosomes, such as the human Y chromosome ...
• SOX17 enhancer variants disrupt transcription factor binding and enhancer inactivity drives pulmonary hypertension

  Walters, Rachel; Vasilaki, Eleni; Arman, Jurjan; Chen, Chien-Nien; Wu, Yukyee; Liang, Olin D.; Ashek, Ali; Dubois, Olivier; Zhao, Lin; Sabrin, Farah; Cebola, Inês; Ferrer, Jorge; Morrell, Nicholas W.; Klinger, James R.; Wilkins, Martin R.; Zhao, Lan; Rhodes, Christopher J. (Wolters Kluwer (LWW), 2023)

  Background: Pulmonary arterial hypertension (PAH) is a rare disease characterized by remodeling of the pulmonary arteries, increased vascular resistance, and right-sided heart failure. Genome-wide association studies of ...
• Evidence for the effectiveness of interventions to reduce mental health related stigma in the workplace: a systematic review

  Tóth, Mónika Ditta; Ihionvien, Sarah; Leduc, Caleb; Aust, Birgit; Amann, Benedikt Lorenz; Cresswell-Smith, Johanna; Reich, Hanna; Cully, Grace; Sanches, Sarita; Fanaj, Naim; Qirjako, Gentiana; Tsantila, Fotini; Ross, Victoria; Mathieu, Sharna; Pashoja, Arlinda Cerga; Arensman, Ella; Purebl, György; MENTUPP consortium members (BMJ Publishing Group, 2023)

  Objectives: Increasing access to mental health support is a key factor for treating mental disorders, however, important barriers complicate help-seeking, among them, mental health related stigma being most prominent. We ...
• Eigenvector centrality dynamics are related to Alzheimer’s disease pathological changes in non-demented individuals

  Lorenzini, Luigi; Gispert López, Juan Domingo; Wink, Alle Meije (Oxford University Press, 2023)

  Amyloid-β accumulation starts in highly connected brain regions and is associated with functional connectivity alterations in the early stages of Alzheimer's disease. This regional vulnerability is related to the high ...
• Differential effects of sleep on brain structure and metabolism at the preclinical stages of AD

  Stankeviciute, Laura; Falcón, Carles; Operto, Grégory; Garcia, Marina; Shekari, Mahnaz; Iranzo, Alex; Niñerola-Baizán, Aida; Perissinotti, Andrés; Minguillón, Carolina; Fauria, Karine; Molinuevo, José Luis; Zetterberg, Henrik; Blennow, Kaj; Suárez-Calvet, Marc; Cacciaglia, Raffaele; Gispert López, Juan Domingo; Grau-Rivera, Oriol; ALFA Study (Wiley, 2023)

  Introduction: Poor sleep quality is associated with cognitive outcomes in Alzheimer's disease (AD). We analyzed the associations between self-reported sleep quality and brain structure and function in cognitively unimpaired ...
• Plasma and CSF biomarkers in a memory clinic: head-to-head comparison of phosphorylated tau immunoassays

  Ashton, Nicholas J.; Puig Pijoan, Albert; Milà Alomà, Marta; Fernández-Lebrero, Aida; Ortiz Romero, Paula, 1994-; Minguillón, Carolina; Navalpotro-Gómez, Irene; Grau-Rivera, Oriol; Manero, Rosa María; Puente Periz, Victor Manuel; Torre Fornell, Rafael de la; Roquer, Jaume; Suárez-Calvet, Marc (Wiley, 2023)

  Introduction: Direct comparisons of the main blood phosphorylated tau immunoassays in memory clinic populations are needed to understand possible differences. Methods: In the BIODEGMAR study, 197 participants presenting ...
• Obstetric complications and genetic risk for schizophrenia: differential role of antenatal and perinatal events in first episode psychosis

  Valli, Isabel; González Segura, Àlex; Verdolini, Norma; García-Rizo, Clemente; Berge Baquero, Daniel; Baeza, Immaculada; Cuesta, Manuel J.; Gonzalez-Pinto, Ana; Lobo, Antonio; Martinez-Aran, Anabel; Mezquida, Gisela; Pina-Camacho, Laura; Roldan Bejarano, Alexandra; Mas, Sergi; McGuire, Philip; Bernardo, Miquel; Vieta, Eduard; PEPs Group (Wiley, 2023)

  Background: Obstetric complications (OCs) are key contributors to psychosis risk. However, it is unclear whether they increase psychosis vulnerability independently of genetic risk, in interaction with it, or are a ...
• Assessing real-world gait with digital technology? Validation, insights and recommendations from the Mobilise-D consortium

  Micó-Amigo, M. Encarna; Carsin, Anne-Elie; García Aymerich, Judith; Koch, Sarah; Mobilise-D consortium (BioMed Central, 2023)

  Background: Although digital mobility outcomes (DMOs) can be readily calculated from real-world data collected with wearable devices and ad-hoc algorithms, technical validation is still required. The aim of this paper is ...
• Referential communication in heterogeneous communities of pre-trained visual deep networks

  Mahaut, Matéo; Franzon, Francesca; Dessì, Roberto; Baroni, Marco (International Foundation for Autonomous Agents and Multiagent Systems (IFAAMAS), 2023-07-31)

  As large pre-trained image-processing neural networks are being embedded in autonomous agents such as self-driving cars or robots, the question arises of how such systems can communicate with each other about the ...
• Land titling and litigation

  Arruñada, Benito; Fabbri, Marco; Faure, Michael (University of Chicago Press, 2022)

  We study a land-titling reform implemented as a randomized control trial to isolate its effects on litigation. The reform consisted of demarcating land parcels, registering existing customary rights, and granting additional ...

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