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Visualitza Documents OpenAIRE (Open Access Infrastructure for Research in Europe) per autoria "Yus, Eva"

Ara mostrant els elements 1-9 de 9

A reporter system coupled with high-throughput sequencing unveils key bacterial transcription and translation determinants

Yus, Eva; Yang, Jae-Seong; Sogues, Adrià; Serrano Pubull, Luis, 1982- (Nature Publishing Group, 2017)

Quantitative analysis of the sequence determinants of transcription and translation regulation is relevant for systems and synthetic biology. To identify these determinants, researchers have developed different methods of ...
Comprehensive quantitative modeling of translation efficiency in a genome-reduced bacterium

Weber, Marc; Sogues, Adrià; Yus, Eva; Burgos, Raul; Gallo López, Carolina, 1984-; Martínez, Sira; Lluch-Senar, Maria 1982-; Serrano Pubull, Luis, 1982- (EMBO Press, 2023)

Translation efficiency has been mainly studied by ribosome profiling, which only provides an incomplete picture of translation kinetics. Here, we integrated the absolute quantifications of tRNAs, mRNAs, RNA half-lives, ...
Defined chromosome structure in the genome-reduced bacterium Mycoplasma pneumoniae

Trussart, Marie, 1985-; Yus, Eva; Martínez, Sira; Baù, Davide; Tahara, Yuhei O.; Pengo, Thomas; Widjaja, Michael; Kretschmer, Simon; Swoger, Jim; Djordjevic, Steven P.; Turnbull, Lynne; Whitchurch, Cynthia B.; Miyata, Makoto; Martí Renom, Marc A.; Lluch-Senar, Maria 1982-; Serrano Pubull, Luis, 1982- (Nature Publishing Group, 2017)

DNA-binding proteins are central regulators of chromosome organization; however, in genome-reduced bacteria their diversity is largely diminished. Whether the chromosomes of such bacteria adopt defined three-dimensional ...
Determination of the gene regulatory network of a genome-reduced bacterium highlights alternative regulation independent of transcription factors

Yus, Eva; Lloréns Rico, Verónica, 1989-; Martínez, Sira; Gallo López, Carolina, 1984-; Eilers, Hinnerk; Blötz, Cedric; Stülke, Jörg; Lluch-Senar, Maria 1982-; Serrano Pubull, Luis, 1982- (Elsevier, 2019)

Here, we determined the relative importance of different transcriptional mechanisms in the genome-reduced bacterium Mycoplasma pneumoniae, by employing an array of experimental techniques under multiple genetic and ...
Dissecting the energy metabolism in Mycoplasma pneumoniae through genome-scale metabolic modeling

Wodke, Judith A.H.; Puchalka, Jacek; Lluch-Senar, Maria 1982-; Marcos del Águila, Josep, 1971-; Yus, Eva; Godinho, Miguel; Gutiérrez Gallego, Ricardo, 1968-; Martins dos Santos, Vitor; Serrano Pubull, Luis, 1982-; Klipp, E., 1965-; Maier, Tobias (Nature Publishing Group, 2013)

Mycoplasma pneumoniae, a threatening pathogen with a minimal genome, is a model organism for bacterial systems biology for which substantial experimental information is available. With the goal of understanding the complex ...
Impact of C-terminal amino acid composition on protein expression in bacteria

Weber, Marc; Burgos, Raul; Yus, Eva; Yang, Jae-Seong; Lluch-Senar, Maria 1982-; Serrano Pubull, Luis, 1982- (EMBO Press, 2020)

The C-terminal sequence of a protein is involved in processes such as efficiency of translation termination and protein degradation. However, the general relationship between features of this C-terminal sequence and levels ...
Integration of multi-omics data of a genome-reduced bacterium: Prevalence of post-transcriptional regulation and its correlation with protein abundances

Chen, Wei-Hua; van Noort, Vera; Lluch-Senar, Maria 1982-; Hennrich, Marco L.; Wodke, Judith A.H.; Yus, Eva; Alibés, Andreu; Roma, Guglielmo; Mende, Daniel R.; Pesavento, Christina; Typas, Athanasios; Gavin, Anne-Claude; Serrano Pubull, Luis, 1982- (Oxford University Press, 2016)

We developed a comprehensive resource for the genome-reduced bacterium Mycoplasma pneumoniae comprising 1748 consistently generated '-omics' data sets, and used it to quantify the power of antisense non-coding RNAs (ncRNAs), ...
MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae

Wodke, Judith A.H.; Alibés, Andreu; Cozzuto, Luca; Hermoso Pulido, Antonio; Yus, Eva; Lluch-Senar, Maria 1982-; Serrano Pubull, Luis, 1982-; Roma, Guglielmo (Oxford University Press, 2015)

MyMpn (http://mympn.crg.eu) is an online resource devoted to studying the human pathogen Mycoplasma pneumoniae, a minimal bacterium causing lower respiratory tract infections. Due to its small size, its ability to grow in ...
Transcription start site associated RNAs in bacteria

Yus, Eva; Güell Cargol, Marc, 1982-; Vivancos Prellezo, Ana; Chen, Wei-Hua; Lluch-Senar, Maria 1982-; Delgado Blanco, Javier; Gavin, Anne-Claude; Bork, Peer; Serrano Pubull, Luis, 1982- (Nature Publishing Group, 2012)

Here, we report the genome-wide identification of small RNAs associated with transcription start sites (TSSs), termed tssRNAs, in Mycoplasma pneumoniae. tssRNAs were also found to be present in a different bacterial phyla, ...