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Browsing Documents OpenAIRE (Open Access Infrastructure for Research in Europe) by Author "Prats, Neus"

Browsing Documents OpenAIRE (Open Access Infrastructure for Research in Europe) by Author "Prats, Neus"

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  • Deciphering the roadmap of in vivo reprogramming toward pluripotency
    Chondronasiou, Dafni; Martínez de Villarreal, Jaime; Melendez, Elena; Lynch, Cian J.; Pozo, Natalia del; Kovatcheva, Marta; Aguilera, Mònica; Prats, Neus; Real, Francisco X.; Serrano, Manuel (Elsevier, 2022)
    Differentiated cells can be converted into pluripotent stem cells by expressing the transcription factors OCT4, SOX2, KLF4, and MYC (OSKM) in a process known as reprogramming. Here, using single-cell RNA sequencing of ...
  • Loss of dnmt3a and dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-g
    Rinaldi, Lorenzo, 1986-; Avgustinova, Alexandra; Martín, Mercè; Datta, Debayan; Solanas, Guiomar; Prats, Neus; Aznar Benitah, Salvador (eLife, 2017)
    The DNA methyltransferase Dnmt3a suppresses tumorigenesis in models of leukemia and lung cancer. Conversely, deregulation of Dnmt3b is thought to generally promote tumorigenesis. However, the role of Dnmt3a and Dnmt3b in ...
  • Targeting lymphoid-derived IL-17 signaling to delay skin aging
    Solá, Paloma; Mereu, Elisabetta; Bonjoch, Júlia; Casado-Peláez, Marta; Prats, Neus; Aguilera, Mònica; Reina García, Óscar, 1976-; Blanco, Enrique; Esteller, Manel; Di Croce, Luciano; Heyn, Holger; Solanas, Guiomar; Aznar Benitah, Salvador (Nature Research, 2023)
    Skin aging is characterized by structural and functional changes that contribute to age-associated frailty. This probably depends on synergy between alterations in the local niche and stem cell-intrinsic changes, underscored ...

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