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Browsing Documents OpenAIRE (Open Access Infrastructure for Research in Europe) by Author "O'Hanlon, Dave"

Browsing Documents OpenAIRE (Open Access Infrastructure for Research in Europe) by Author "O'Hanlon, Dave"

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  • A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons
    Torres Méndez, Antonio; Bonnal, Sophie; Marquez, Yamile; Roth, Jonathan; Iglesias, Marta; Permanyer, Jon; Almudi, Isabel; O'Hanlon, Dave; Guitart, Tanit; Soller, Matthias; Gingras, Anne-Claude; Gebauer, Fátima; Rentzsch, Fabian; Blencowe, Benjamin J.; Valcárcel, J. (Juan); Irimia Martínez, Manuel (Nature Research, 2019)
    The mechanisms by which entire programmes of gene regulation emerged during evolution are poorly understood. Neuronal microexons represent the most conserved class of alternative splicing in vertebrates, and are critical ...

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