Welcome to the UPF Digital Repository

Browsing Documents OpenAIRE (Open Access Infrastructure for Research in Europe) by Title

Browsing Documents OpenAIRE (Open Access Infrastructure for Research in Europe) by Title

Sort by: Order: Results:

  • CEBPA phase separation links transcriptional activity and 3D chromatin hubs
    Christou-Kent, Marie; Cuartero, Sergi; Garcia-Cabau, Carla; Ruehle, Julia; Naderi, Julian; Erber, Julia; Neguembor, Maria Victoria; Plana Carmona, Marcos, 1993-; Alcoverro-Bertran, Marc; Andrés Aguayo, Luisa de; Klonizakis, Antonios; Julià Vilella, Eric; Lynch, Cian J.; Serrano, Manuel; Hnisz, Denes; Salvatella, Xavier; Graf, T. (Thomas); Stik, Grégoire (Elsevier, 2023)
    Cell identity is orchestrated through an interplay between transcription factor (TF) action and genome architecture. The mechanisms used by TFs to shape three-dimensional (3D) genome organization remain incompletely ...
  • Cell cycle transcriptomics of Capsaspora provides insights into the evolution of cyclin-CDK machinery
    Pérez-Posada, Alberto, 1993-; Dudin, Omaya; Ocaña Pallarès, Eduard, 1991-; Ruiz Trillo, Iñaki; Ondracka, Andrej (Public Library of Science (PLoS), 2020)
    Progression through the cell cycle in eukaryotes is regulated on multiple levels. The main driver of the cell cycle progression is the periodic activity of cyclin-dependent kinase (CDK) complexes. In parallel, transcription ...
  • Cell lineage infidelity in PDAC progression and therapy resistance
    Malinova, Antonia; Veghini, Lisa; Real, Francisco X.; Corbo, Vincenzo (Frontiers, 2021)
    Infidelity to cell fate occurs when differentiated cells lose their original identity and either revert to a more multipotent state or transdifferentiate into a different cell type, either within the same embryonic lineage ...
  • Cell type-specific novel long non-coding RNA and circular RNA in the BLUEPRINT hematopoietic transcriptomes atlas
    Grassi, Luigi; Bustamante Pineda, Mariona; Frontini, Mattia (Ferrata Storti Foundation, 2021)
    Transcriptional profiling of hematopoietic cell subpopulations has helped to characterize the developmental stages of the hematopoietic system and the molecular bases of malignant and non-malignant blood diseases. Previously, ...
  • Cell-free DNA for genomic analysis in primary mediastinal large B-cell lymphoma
    Rivas-Delgado, Alfredo; Nadeu, Ferran; Andrade-Campos, Marcio; López, Cristina; Enjuanes¸ Anna; Mozas, Pablo; Frigola, Gerard; Colomo Saperas, Luis Alberto; Sánchez González, Blanca; Villamor, Neus; Beà, Sílvia; Campo, Elias; Salar Silvestre, Antonio; Giné, Eva; López Guillermo, Armando; Bellosillo Paricio, Beatriz (MDPI, 2022)
    High-throughput sequencing of cell-free DNA (cfDNA) has emerged as a promising noninvasive approach in lymphomas, being particularly useful when a biopsy specimen is not available for molecular analysis, as it frequently ...
  • Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids
    Hashmi, Ali; Tlili, Sham; Perrin, Pierre; Lowndes, Molly; Peradziryi, Hanna; Brickman, Joshua M.; Martínez Arias, Alfonso; Lenne, Pierre-François (eLife, 2022)
    Shaping the animal body plan is a complex process that involves the spatial organization and patterning of the different germ layers. Recent advances in live imaging have started to unravel the cellular choreography ...
  • Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids
    Puighermanal Puigvert, Emma, 1983-; Busquets Garcia, Arnau, 1985-; Maldonado, Rafael, 1961-; Ozaita Mintegui, Andrés, 1969- (Royal Society, 2012)
    Exogenous cannabinoids, such as delta9-tetrahydrocannabinol (THC), as well as the modulation of endogenous cannabinoids, affect cognitive function through the activation of cannabinoid receptors. Indeed, these compounds ...
  • Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers
    Salvadó, Gemma; Molinuevo, José Luis; Brugulat Serrat, Anna, 1986-; Falcón, Carles; Grau-Rivera, Oriol; Suárez-Calvet, Marc; Pavía Segura, Javier; Niñerola-Baizán, Aida; Perissinotti, Andrés; Lomeña, Francisco; Minguillón, Carolina; Fauria, Karine; Zetterberg, Henrik; Blennow, Kaj; Gispert López, Juan Domingo; Alzheimer’s Disease Neuroimaging Initiative (BioMed Central, 2019)
    Background: The Centiloid scale has been developed to standardize measurements of amyloid PET imaging. Reference cut-off values of this continuous measurement enable the consistent operationalization of decision-making for ...
  • cGLRs are a diverse family of pattern recognition receptors in innate immunity
    Li, Yao; Slavik, Kailey M.; Toyoda, Hunter C.; Morehouse, Benjamin R.; Oliveira Mann, Carina C. de; Elek, Anamaria; Levy, Shani; Wang, Zhenwei; Mears, Kepler S.; Liu, Jingjing; Kashin, Dmitry; Guo, Ximing; Mass, Tali; Sebé-Pedrós, Arnau; Schwede, Frank; Kranzusch, Philip J. (Elsevier, 2023)
    Cyclic GMP-AMP synthase (cGAS) is an enzyme in human cells that controls an immune response to cytosolic DNA. Upon binding DNA, cGAS synthesizes a nucleotide signal 2'3'-cGAMP that activates STING-dependent downstream ...
  • Challenges for visualizing three‐dimensional data in genomic browsers
    Goodstadt, Mike N.; Marti-Renom, Marc A. (Wiley, 2017)
    Genomic interactions reveal the spatial organization of genomes and genomic domains, which is known to play key roles in cell function. Physical proximity can be represented as two-dimensional heat maps or matrices. From ...
  • Challenges in including extra-linguistic context in pre-trained language models
    Sorodoc, Ionut-Teodor; Aina, Laura; Boleda, Gemma (ACL (Association for Computational Linguistics), 2022)
    To successfully account for language, computational models need to take into account both the linguistic context (the content of the utterances) and the extra-linguistic context (for instance, the participants in a dialogue). ...
  • Challenges with sign language datasets for sign language recognition and translation
    De Sisto, Mirella; Vandeghinste, Vincent; Egea Gómez, Santiago; De Coster, Mathieu; Shterionov, Dimitar; Saggion, Horacio (European Language Resources Association, 2022)
    Sign Languages (SLs) are the primary means of communication for at least half a million people in Europe alone. However, the development of SL recognition and translation tools is slowed down by a series of obstacles ...
  • Challenging the boundaries of the physical self: distal cues impact body ownership
    Grechuta, Klaudia; Torre Costa, Javier de la; Rubio Ballester, Belén; Verschure, Paul F. M. J. (Frontiers, 2021)
    The unique ability to identify one’s own body and experience it as one’s own is fundamental in goal-oriented behavior and survival. However, the mechanisms underlying the so-called body ownership are yet not fully understood. ...
  • Change and continuity in the fertility of unpartnered women in Latin America, 1980–2010
    Laplante, Benoît; Castro Martín, Teresa; Cortina Trilla, Clara (Max Planck Institute for Demographic Research, 2018)
    Over the last decades, the proportion of children born to unmarried mothers has been increasing in Latin America while unmarried cohabitation has become more common. One would expect the former to be a consequence of the ...
  • Changes in gene expression predictably shift and switch genetic interactions
    Li, Xianghua; Lalić, Jasna; Baeza Centurión, Pablo, 1989-; Dhar, Riddhiman; Lehner, Ben, 1978- (Nature Research, 2019)
    Non-additive interactions between mutations occur extensively and also change across conditions, making genetic prediction a difficult challenge. To better understand the plasticity of genetic interactions (epistasis), we ...
  • Changes in synaptic proteins precede neurodegeneration markers in preclinical Alzheimer's disease cerebrospinal fluid
    Lleó, Alberto; Chiva, Cristina; Sabidó Aguadé, Eduard, 1981-; Belbin, Olivia (Elsevier, 2019)
    A biomarker of synapse loss, an early event in Alzheimer's disease (AD) pathophysiology that precedes neuronal death and symptom onset, would be a much-needed prognostic biomarker. With direct access to the brain interstitial ...
  • Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations
    Kuzmanic, Antonija; Sutto, Ludovico; Saladino, Giorgio; Nebreda, Ángel R.; Gervasio, Francesco L.; Orozco, Modesto (eLife, 2017)
    p38α is a Ser/Thr protein kinase involved in a variety of cellular processes and pathological conditions, which makes it a promising pharmacological target. Although the activity of the enzyme is highly regulated, its ...
  • Changing the urban design of cities for health: The superblock model
    Mueller, Natalie, 1988-; Rojas Rueda, David, 1979-; Khreis, Haneen; Cirach, Marta; Andrés, David; Ballester, Joan; Bartoll, Xavier; Daher, Carolyn; Deluca, Anna; Echave, Cynthia; Milà, Carles; Márquez, Sandra; Palou, Joan; Pérez, Katherine; Tonne, Cathryn; Stevenson, Mark; Rueda, Salvador; Nieuwenhuijsen, Mark J. (Elsevier, 2020)
    Background: Car-dependent city planning has resulted in high levels of environmental pollution, sedentary lifestyles and increased vulnerability to the effects of climate change. The Barcelona Superblock model is an ...
  • Characteristic sounds facilitate object search in real-life scenes
    Kvasova, Daria, 1989-; Garcia-Vernet, Laia; Soto-Faraco, Salvador, 1970- (Frontiers, 2019)
    Real-world events do not only provide temporally and spatially correlated information across the senses, but also semantic correspondences about object identity. Prior research has shown that object sounds can enhance ...
  • Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study
    Reyes, Carlen; Sorlí, Luisa; López Montesinos, Inmaculada; Duarte Salles, Talita, 1985- (BMJ Publishing Group, 2021)
    Objective: To characterise patients with and without prevalent hypertension and COVID-19 and to assess adverse outcomes in both inpatients and outpatients. Design and setting: This is a retrospective cohort study using 15 ...

Search DSpace


Advanced Search

Browse

My Account

In collaboration with Compliant to Partaking