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Browsing Documents OpenAIRE (Open Access Infrastructure for Research in Europe) by Title

Browsing Documents OpenAIRE (Open Access Infrastructure for Research in Europe) by Title

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  • Batard, Thomas; Bertalmío, Marcelo (Springer, 2013)
    We introduce a gradient operator that generalizes the Eu- clidean and Riemannian gradients. This operator acts on sections of vector bundles and is determined by three geometric data: a Rieman- nian metric on the base ...
  • López Massaguer, Oriol, 1972-; Pinto Gil, Kevin; Sanz, Ferran; Amberg, Alexander; Anger, Lennart T; Stolte, Manuela; Ravagli, Carlo; Marc, Philippe; Pastor Maeso, Manuel (Oxford University Press, 2018)
    Over the past decades, pharmaceutical companies have conducted a large number of high-quality in vivo repeat-dose toxicity (RDT) studies for regulatory purposes. As part of the eTOX project, a high number of these studies ...
  • Aragón, Pablo; Gómez, Vicenç; García, David; Kaltenbrunner, Andreas (SpringerOpen, 2017)
    Online discussion in form of written comments is a core component of many social media platforms. It has attracted increasing attention from academia, mainly because theories from social sciences can be explored at an ...
  • Rubio Pérez, Carlota, 1990-; Güney, Emre, 1983-; Aguilar, Daniel; Piñero González, Janet, 1977-; García-García, Javier, 1982-; Iadarola, Barbara; Sanz, Ferran; Fernández Fuentes, Narcís; Furlong, Laura I., 1971-; Oliva Miguel, Baldomero (Nature Publishing Group, 2017)
    Understanding relationships between diseases, such as comorbidities, has important socio-economic implications, ranging from clinical study design to health care planning. Most studies characterize disease comorbidity using ...
  • Nevado-Holgado, Alejo J.; Ribe, Elena; Thei, Laura; Furlong, Laura I., 1971-; Mayer Pujadas, Miguel Ángel; Quan, Jie; Richardson, Jill C.; Cavanagh, Jonathan; NIMA Consortium; Loveston, Simon (MDPI, 2019)
    As genome-wide association studies (GWAS) have grown in size, the number of genetic variants that have been associated per disease has correspondingly increased. Despite this increase in the number of single-nucleotide ...
  • Pineda, Silvia; Milne, Roger L.; Calle, M. Luz; Rothman, Nathaniel; López De Maturana, Evangelina; Herranz, Jesús; Kogevinas, Manolis; Chanock, Stephen J.; Tardón, Adonina; Márquez, Mirari; Guey, Lin T.; García Closas, Montserrat; Lloreta Trull, Josep, 1958-; Baum, Erin; González Neira, Anna; Carrato, Alfredo; Navarro i Cuartiellas, Arcadi, 1969-; Silverman, Debra T.; Real, Francisco X.; Malats i Riera, Núria (Public Library of Science (PLoS), 2014)
    Introduction: Germline variants in TP63 have been consistently associated with several tumors, including bladder cancer, indicating the importance of TP53 pathway in cancer genetic susceptibility. However, variants in other ...
  • Kotlobay, Alexey A.; Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973-; Yampolsky, Ilia V. (National Academy of Sciences, 2018)
    Bioluminescence is found across the entire tree of life, conferring a spectacular set of visually oriented functions from attracting mates to scaring off predators. Half a dozen different luciferins, molecules that emit ...
  • Pryszcz, Leszek Piotr, 1985-; Németh, Tibor; Gácser, Attila; Gabaldón Estevan, Juan Antonio, 1973- (Oxford University Press, 2014)
    The Candida parapsilosis species complex comprises a group of emerging human pathogens of varying virulence. This complex was recently subdivided into three different species: C. parapsilosis sensu stricto, C. metapsilosis, ...
  • Carreté Muñoz, Laia, 1990-; Ksiezopolska, Ewa; Gómez-Molero, Emilia; Angoulvant, Adela; Bader, Olivier; Fairhead, Cécile; Gabaldón Estevan, Juan Antonio, 1973- (Frontiers, 2019)
    Candida glabrata is an opportunistic fungal pathogen that currently ranks as the second most common cause of candidiasis. Although the mechanisms underlying virulence and drug resistance in C. glabrata are now starting to ...
  • Balboa, Diego; Prasad, Rashmi B.; Groop, Leif; Otonkoski, Timo (Springer, 2019)
    Understanding the molecular mechanisms behind beta cell dysfunction is essential for the development of effective and specific approaches for diabetes care and prevention. Physiological human beta cell models are needed ...
  • Naranjo Ortiz, Miguel Ángel, 1989-; Rodríguez-Píres, Silvia; Torres, Rosario; De Cal, Antonieta; Usall, Josep; Gabaldón Estevan, Juan Antonio, 1973- (American Society for Microbiology, 2018)
    Monilinia laxa (phylum Ascomycota) is a plant pathogen responsible for the brown rot blossom blight disease in stone fruit trees of the Rosaceae family, such as apricots. We report here the genome sequence of strain 8L of ...
  • Banani, Houda; Marcet Houben, Marina; Ballester, Ana Rosa; Abbruscato, Pamela; González Candelas, Luis; Gabaldón Estevan, Juan Antonio, 1973-; Spadaro, Davide (BioMed Central, 2016)
    BACKGROUND: Penicillium griseofulvum is associated in stored apples with blue mould, the most important postharvest disease of pome fruit. This pathogen can simultaneously produce both detrimental and beneficial secondary ...
  • Freedman, Adam H; Lorente-Galdós, Belén, 1981-; Ramírez, Oscar; Marquès i Bonet, Tomàs, 1975-; Novembre, John (Public Library of Science (PLoS), 2014)
    To identify genetic changes underlying dog domestication and reconstruct their early evolutionary history, we generated high-quality genome sequences from three gray wolves, one from each of the three putative centers of ...
  • González-Torres, Pedro; Gabaldón Estevan, Juan Antonio, 1973- (Frontiers, 2018)
    The halophilic bacterium Salinibacter ruber is an abundant and ecologically important member of halophilic communities worldwide. Given its broad distribution and high intraspecific genetic diversity, S. ruber is considered ...
  • Ballester, Ana Rosa; Marcet Houben, Marina; Levin, Elena; Sela, Noa; Selma Lázaro, Cristina; Carmona, Lourdes; Wisniewski, Michael; Droby, Samir; González Candelas, Luis; Gabaldón Estevan, Juan Antonio, 1973- (APS Press, 2015)
    The relationship between secondary metabolism and infection in pathogenic fungi has remained largely elusive. The genus Penicillium comprises a group of plant pathogens with varying host specificities and with the ability ...
  • Corvelo, André; Hallegger, Martina; Smith, Christopher, W. J.; Eyras Jiménez, Eduardo (Public Library of Science (PLoS), 2010)
    The branch point (BP) is one of the three obligatory signals required for pre-mRNA splicing. In mammals, the degeneracy of the motif combined with the lack of a large set of experimentally verified BPs complicates the task ...
  • Marenne, Gaëlle; Real, Francisco X.; Rothman, Nathaniel; Rodríguez Santiago, Benjamín; Pérez Jurado, Luis Alberto; Kogevinas, Manolis; García Closas, Montserrat; Silverman, Debra T.; Chanock, Stephen J.; Génin, Emmanuelle; Malats i Riera, Núria (BioMed Central, 2012)
    BACKGROUND: Structural variations such as copy number variants (CNV) influence the expression of different phenotypic traits. Algorithms to identify CNVs through SNP-array platforms are available. The ability to evaluate ...
  • Haber, Marc, 1980-; Gauguier, Dominique; Youhanna, Sonia; Patterson, Nick; Moorjani, Priya; Botigué, Laura R; Platt, Daniel E.; Matisoo Smith, Elizabeth; Soria Hernanz, David F; Wells, R. Spencer; Bertranpetit, Jaume, 1952-; Tyler-Smith, Chris; Comas, David, 1969-; Zalloua, Pierre A. (Public Library of Science (PLoS), 2013)
    The Levant is a region in the Near East with an impressive record of continuous human existence and major cultural developments since the Paleolithic period. Genetic and archeological studies present solid evidence placing ...
  • Gabaldón Estevan, Juan Antonio, 1973-; Fairhead, Cécile (Springer, 2019)
    Candida glabrata is an opportunistic yeast pathogen, whose incidence has increased over the last decades. Despite its genus name, this species is actually more closely related to the budding yeast Saccharomyces cerevisiae ...
  • Olalde Marquínez, Íñigo, 1987-; Sánchez Quinto, Federico A, 1985-; Datta, Debayan; Marigorta, Urko M.; Chiang, Charleston W.K.; Rodríguez, Juan Antonio; Fernández Callejo, Marcos; González Navarrete, Irene, 1983-; Montfort, Magda; Matas Lalueza, Laura; Civit, Sergi; Luiselli, Donata; Charlier, Philippe; Pettener, Davide; Ramírez, Oscar; Navarro i Cuartiellas, Arcadi, 1969-; Himmelbauer, Heinz; Marquès i Bonet, Tomàs, 1975-; Lalueza Fox, Carles, 1965- (Nature Publishing Group, 2014)
    A pyrographically decorated gourd, dated to the French Revolution period, has been alleged to contain a handkerchief dipped into the blood of the French king Louis XVI (1754–1793) after his beheading but recent analyses ...

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