Tesis doctorals llegides a la UPF en format digital en accés obert introduïdes a la plataforma TDX (Tesis Doctorals en Xarxa), on també es poden consultar tesis d'altres centres.
Since the origins of humankind, North Africa has been involved in many demographic events, leading to a heterogeneous cultural and genetic landscape. However, it is largely underrepresented in genetic studies, and many ...
García Fernández, Jéssica(Universitat Pompeu Fabra, 2023-06-27)
The term "neurodegenerative disorder" refers to a set of illnesses in which the neurological system gradually deteriorates and is characterized by cognitive impairment, motor degradation, and behavioural changes. The ...
García García, Marcos José(Universitat Pompeu Fabra, 2023-07-04)
El presente trabajo analiza la participación española en la Guerra de Sucesión Polaca y sostiene, como resultado, que dicho conflicto no responde al modelo de guerra dieciochista que la historiografía ha presentado hasta ...
Kennedy, Keith Endres(Universitat Pompeu Fabra, 2023-06-27)
This thesis focuses on the multiscale nature of the biological process that underpin the function of all living systems. A first project centers on the disease known as multiple sclerosis, and utilizes various datasets at ...
García Baos, Alba(Universitat Pompeu Fabra, 2023-09-27)
Alcohol exposure during gestation and lactation leads to physical and behavioral disabilities known as fetal alcohol spectrum disorder. Although cognitive dysfunction is highly frequent and compromises the patients’ quality ...
This thesis introduces SIMPLE (Structured Illumination based Point Lo- calization Estimator), a novel super-resolution technique in fluorescence microscopy. By combining standing-wave patterned illumination with single-molecule ...
Adopting a bottom-up approach, and taking the EU‒Turkey deal as a case study, this Ph.D. thesis provides empirical evidence about the impact of externalisation policies on refugees’ daily lives and on their onward migration ...
Memory is a physiological brain function crucial for adaptive behaviour of individuals. Memory alterations are described as impairments in the processes by which memory is perceived, encoded, consolidated, retrieved, or ...
This thesis consists of three chapters on topics in Macroeconometrics. Chapter 1 develops
a hypothesis test to evaluate economic models and their forecasts robust to instabilities.
The test is particularly powerful in the ...
Macrophages play crucial roles in the defense of the organism against a wide range of pathogens. Macrophages can rapidly adapt to perturbations in the microenvironment due to the existence of a network of transcription ...
El principal objetivo de la tesis doctoral es profundizar en el conocimiento de la imposición y ejecución de la sanción de separación del grupo por días en España y Catalunya. Para ello, se lleva a cabo un análisis legislativo ...
Autoinflammatory diseases are caused by an antigen independent hyperactivation of inflammatory pathways. The first genetic defect linked to an autoinflammatory disease was described almost 25 years ago and, since then, the ...
Els pacients diagnosticats amb esquizofrènia o un primer episodi psicòtic (PEP) que consumeixen cànnabis presenten alteracions clíniques diferencials comparats amb els no consumidors. En aquesta tesi doctoral, hem emprat ...
Yeast deal with continuous environmental perturbations that compromise its cell fitness. Upon osmostress, HOG pathway becomes activated and leads the adaptation response. To compensate the osmotic imbalance, Hog1 is in ...
Tolosa Ramon, Queralt(Universitat Pompeu Fabra, 2023-09-15)
The outer epithelial layer is the first cell type that emerges during development, providing essential mechanical protection and is indispensable for morphogenesis. Here, we study how the interplay between molecular and ...
Embryonic stem cells (ESCs) are derived from the inner cell mass of the pre-implantation embryo and can recapitulate early developmental stages of the embryo. ESCs have the ability to continuously propagate while maintaining ...
Cocaine use profoundly disrupts the neuronal circuits that regulate reward processing, motivation and decision making, resulting in long-lasting neuroplastic adaptations in the mesocorticolimbic system. The endocannabinoid ...
Our everyday life is plenty of social interactions, but there are still many unknowns about the mechanisms supporting them. The current dissertation aims to explore the neurocognitive processes that underlie interactions ...
Chromocenters are established after the 2-cell (2C) stage during mouse embryonic development, but the factors that mediate chromocenter formation remain largely unknown. To identify regulators of 2C heterochromatin ...
Emotions are a fundamental part of human life. They play a critical role in how we think, behave, and implicitly understand each other. However, although computing devices are increasingly consequential in our world, they ...