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Articles (Departament de Ciències Experimentals i de la Salut)

Articles (Departament de Ciències Experimentals i de la Salut)

 

Articles de recerca, en accés obert, del Departament de Ciències Experimentals i de la Salut de la UPF.

Recent Submissions

  • Fujishiro, Kaori; Ahonen, Emily; Gimeno Ruiz de Porras, David; Chen, I-Chen; Benavides, Fernando G. (Fernando García) (Elsevier, 2021)
    Work contributes to health and health inequity in complex ways. The traditional exposure-disease framework used in occupational health research is not equipped to address societal contexts in which work is embedded. The ...
  • Soldevila-Domenech, Natalia; Forero, Carlos G.; Alayo, Itxaso; Capella, Jordina; Colom, Joan; Malmusi, Davide, 1980-; Mompart, Anna; Mortier, Philippe; Puértolas Gracia, Beatriz; Sánchez, Néstor; Schiaffino, Anna; Vilagut Saiz, Gemma, 1975-; Alonso Caballero, Jordi (Springer, 2021)
    Purpose: The aim of this study was to analyse the association between individual mental well-being and social, economic, lifestyle and health factors. Methods: Cross-sectional study on a representative sample of 13,632 ...
  • Martin Casals, Miquel; Gutiérrez Martos, Miriam; Cabrera Ortega, Roberto; Langohr, Klaus; Maldonado, Rafael, 1961-; Farré Albaladejo, Magí; Torre Fornell, Rafael de la (Springer, 2021)
    Rationale: Cocaine addiction is a chronic relapsing disorder that lacks of an effective treatment. Isoflavones are a family of compounds present in different plants and vegetables like soybeans that share a common chemical ...
  • Cabañero Ferri, David; Maldonado, Rafael, 1961- (Wiley, 2021)
    Background: The use of paracetamol or nefopam for postoperative pain control is limited by the need of high doses associated with unwanted effects. Previous works suggest positive interactions between both compounds that ...
  • Llinàs-Mallol, Laura; Redondo Pachón, María Dolores; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Yélamos López, José; Duran Jordà, Xavier, 1974-; Faura, Anna; López-Botet, Miguel; Pascual Santos, Julio; Crespo Barrio, Marta (MDPI, 2020)
    Classical immunosuppression based on steroids, calcineurin inhibitors, and mycophenolate results in several unwanted effects and unsatisfactory long-term outcomes in kidney transplantation (KT). New immunosuppressors search ...
  • Hoijman, Esteban; Häkkinen, Hanna-Maria; Tolosa-Ramon, Queralt; Jiménez-Delgado, Senda; Wyatt, Christopher Douglas Robert, 1988-; Miret-Cuesta, Marta; Irimia, Manuel; Callan-Jones, Andrew; Wieser, Stefan; Ruprecht, Verena (Nature Research, 2021)
    Errors in early embryogenesis are a cause of sporadic cell death and developmental failure1,2. Phagocytic activity has a central role in scavenging apoptotic cells in differentiated tissues3-6. However, how apoptotic cells ...
  • Raote, Ishier; Malhotra, Vivek (Annual Reviews Inc, 2021)
    The functions of coat protein complex II (COPII) coats in cargo packaging and the creation of vesicles at the endoplasmic reticulum are conserved in eukaryotic protein secretion. Standard COPII vesicles, however, cannot ...
  • Serres Armero, Aitor; Davis, Brian W.; Povolotskaya, Inna, 1986-; Morcillo Suárez, Carlos, 1969-; Plassais, Jocelyn; Juan, David; Ostrander, Elaine A.; Marquès i Bonet, Tomàs, 1975- (Cold Spring Harbor Laboratory Press (CSHL Press), 2021)
    Extreme phenotypic diversity, a history of artificial selection, and socioeconomic value make domestic dog breeds a compelling subject for genomic research. Copy number variation (CNV) is known to account for a significant ...
  • Castro e Silva, Marcos Araújo; Ferraz, Tiago; Bortolini, Maria Cátira; Comas, David, 1969-; Hünemeier, Tábita (National Academy of Sciences, 2021)
    Different models have been proposed to elucidate the origins of the founding populations of America, along with the number of migratory waves and routes used by these first explorers. Settlements, both along the Pacific ...
  • Kalmykova, Svetlana; Kalinina, Marina; Denisov, Stepan; Mironov, Alexey; Skvortsov, Dmitry; Guigó Serra, Roderic; Pervouchine, Dmitri D. (Nature Research, 2021)
    The ability of nucleic acids to form double-stranded structures is essential for all living systems on Earth. Current knowledge on functional RNA structures is focused on locally-occurring base pairs. However, crosslinking ...
  • Lindskrog, Sia Viborg; Real, Francisco X.; Dyrskjøt, Lars (Nature Research, 2021)
    The molecular landscape in non-muscle-invasive bladder cancer (NMIBC) is characterized by large biological heterogeneity with variable clinical outcomes. Here, we perform an integrative multi-omics analysis of patients ...
  • Martínez, Evelyn; Garin Boronat, Olatz, 1979-; Pardo Cladellas, Yolanda; Fernández, Pablo; Guix, Benjamin; Gutiérrez, Cristina; Boladeras, Ana; Ferrer, Ferran; Hernández, Tania; Ayala, Adriana; Egiguren, Mikel; Fernández, Gema; Muñoz, Víctor; Macías, Víctor; Pera, Joan; Pont Acuña, Àngels; Ferrer, Montserrat; Guedea, Ferrán (Termedia Publishing, 2021)
    Introduction: Brachytherapy (BT) and external beam radiation therapy (EBRT) are effective treatments for high-risk prostate cancer (PCa). However, the impact of these treatments on health-related quality of life (HRQL) ...
  • Toscano Ochoa, Carlos, 1985-; García Ojalvo, Jordi (Elsevier, 2021)
    Processing time-dependent information requires cells to quantify the duration of past regulatory events and program the time span of future signals. At the single-cell level, timer mechanisms can be implemented with genetic ...
  • Ågren, Richard; Stepniewski, Tomasz Maciej, 1988-; Zeberg, Hugo; Selent, Jana; Sahlholm, Kristoffer (MDPI, 2021)
    The forward (kon) and reverse (koff) rate constants of drug-target interactions have important implications for therapeutic efficacy. Hence, time-resolved assays capable of measuring these binding rate constants may be ...
  • Kloesch, Bernhard; Ionasz, Vivien; Paliwal, Sumit; Hruschka, Natascha; Martínez de Villarreal, Jaime; Öllinger, Robert; Mueller, Sebastian; Dienes, Hans Peter; Schindl, Martin; Gruber, Elisabeth S.; Stift, Judith; Herndler-Brandstetter, Dietmar; Lomberk, Gwen A.; Seidler, Barbara; Saur, Dieter; Rad, Roland; Urrutia, Raul A.; Real, Francisco X.; Martinelli, Paola (BMJ Publishing Group, 2021)
    Objective: Molecular taxonomy of tumours is the foundation of personalised medicine and is becoming of paramount importance for therapeutic purposes. Four transcriptomics-based classification systems of pancreatic ductal ...
  • Wang, Yifan; Lobon, Irene; Juan, David; Lizano, Esther; Marquès i Bonet, Tomàs, 1975-; Abyzov, Alexej (BioMed Central, 2021)
    Background: Post-zygotic mutations incurred during DNA replication, DNA repair, and other cellular processes lead to somatic mosaicism. Somatic mosaicism is an established cause of various diseases, including cancers. ...
  • Martín Sánchez, Ana; Piñero González, Janet, 1977-; Nonell Mazelón, Lara; Arnal, Magdalena; Ribe, Elena; Nevado-Holgado, Alejo J.; Lovestone, Simon; Sanz, Ferran; Furlong, Laura I., 1971-; Valverde, Olga (BioMed Central, 2021)
    Background: Major depression (MD) is the most prevalent psychiatric disease in the population and is considered a prodromal stage of the Alzheimer's disease (AD). Despite both diseases having a robust genetic component, ...
  • Cacciaglia, Raffaele; Molinuevo, José Luis; Falcón, Carles; Arenaza Urquijo, Eider M.; Sánchez Benavides, Gonzalo; Brugulat Serrat, Anna, 1986-; Blennow, Kaj; Zetterberg, Henrik; Gispert López, Juan Domingo; ALFA study (Oxford University Press, 2020)
    Gray matter networks (GMn) provide essential information on the intrinsic organization of the brain and appear to be disrupted in Alzheimer's disease (AD). Apolipoprotein E (APOE)-ε4 represents the major genetic risk factor ...
  • Gallego-Fabrega, Cristina; Cullell, Natalia; Soriano Tarraga, Carolina; Carrera, Caty; Torres-Aguila, Nuria P.; Muiño, Elena; Cárcel-Márquez, Jara; Castro de Moura, Manuel; Fernández Sanlés, Alba; Esteller, Manel; Elosua Llanos, Roberto; Jiménez Conde, Jordi; Roquer, Jaume; Montaner, Joan; Krupinski, Jerzy; Fernández-Cadenas, Israel (Impact Journals, 2020)
    Background and purpose: Polymorphisms and serum levels of Matrix Metalloproteinases (MMP) and Tissue Inhibitor of Metalloproteinases (TIMP) have been studied with regard to atheromatous plaques and ischemic stroke, while ...
  • Orkin, Joseph D.; Kuderna, Lukas F.K.; Marquès i Bonet, Tomàs, 1975- (Annual Reviews Inc, 2021)
    Until now, the field of primate genomics has focused on two major themes: understanding human evolution and advancing biomedical research. We propose that it is now time for a third theme to receive attention: conservation ...

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