• Menstrual health and management during the COVID-19 syndemic in the Barcelona area (Spain): a qualitative study

  Holst, Anna Sofie; Jacques-Aviñó, Constanza; Berenguera, Anna; Martínez-Bueno, Cristina; Munrós-Feliu, Jordina; Pinzón-Sanabria, Diana; Valls Llobet, Carme; López-Jiménez, Tomàs; García-Egea, Andrea; Vicente-Hernández, Mª Mercedes; Medina Perucha, Laura (SAGE Publications, 2023)

  Background: Available evidence suggests that menstrual health and management have been impaired during the COVID-19 syndemic. However, research in this area is scarce, and it is failing to voice the experiences of women ...
• Quality of life with palbociclib plus fulvestrant versus placebo plus fulvestrant in postmenopausal women with endocrine-sensitive hormone receptor-positive and HER2-negative advanced breast cancer: patient-reported outcomes from the FLIPPER trial

  Tibau, Ariadna; Martínez, María Teresa; Ramos, Manuel; Cruz-Merino, Luis; Santaballa, Ana; O'Connor, Miriam; Martínez-Jáñez, Noelia; Moreno, Fernando; Fernández, Isaura; Virizuela, Juan Antonio; Alarcón, Jesús; Haba Rodríguez, Juan de la; Sánchez-Rovira, Pedro; Albacar, Cinta Rosa; Bueno Muiño, Carolia; Kelly, Catherine; Casas Sanahuja, Maribel; Bezares, Susana; Rosell, Libertad; Albanell Mestres, Joan (SAGE Publications, 2023)

  Background: In the FLIPPER trial, palbociclib/fulvestrant significantly improved progression-free survival (PFS) compared with placebo/fulvestrant in postmenopausal women with HR+/HER2- advanced breast cancer (ABC). ...
• Could an electronic tool to assess asthma control with a 1-day timeframe be useful for clinical management?

  Ferrer Forés, Maria Montserrat; Lizano-Barrantes, Catalina (Elsevier, 2023)
• The FAIR Cookbook - the essential resource for and by FAIR doers

  Rocca-Serra, Philippe; FAIR Cookbook Contributors; Sansone, Susanna-Assunta (Nature Research, 2023)

  The notion that data should be Findable, Accessible, Interoperable and Reusable, according to the FAIR Principles, has become a global norm for good data stewardship and a prerequisite for reproducibility. Nowadays, FAIR ...
• Considerations for an urban health perspective in Chile from the “Quiero Mi Barrio” program

  Olave-Müller, Paola; López Contreras, Natalia, 1986-; Alvarez Kocher, Patricio; Jirón, Paola; Bass Del Campo, Camilo; Burgos de la Vega, Soledad (Universidade de São Paulo, 2023)

  Objectives: To explore the perceptions of residents regarding their health and well-being in areas of personal and collective life, in relation to the experience of urban transformation originated by the Program for the ...
• Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart

  Milenkovic, Ivan; Santos Vieira, Helaine Graziele; Lucas, Morghan C.; Ruiz-Orera, Jorge; Patone, Giannino; Kesteven, Scott; Wu, Jianxin; Feneley, Michael; Espadas, Guadalupe; Sabidó Aguadé, Eduard, 1981-; Hübner, Norbert; van Heesch, Sebastiaan; Völkers, Mirko; Novoa, Eva Maria (Oxford University Press, 2023)

  The existence of naturally occurring ribosome heterogeneity is now a well-acknowledged phenomenon. However, whether this heterogeneity leads to functionally diverse 'specialized ribosomes' is still a controversial topic. ...
• Cohesin controls X chromosome structure remodeling and X-reactivation during mouse iPSC-reprogramming

  Generoso, Serena Francesca, 1988-; Neguembor, Maria Victoria; Hershberg, Elliot A.; Sadreyev, Ruslan Ilyasovich; Kurimoto, Kazuki; Yabuta, Yukihiro; Ricci, Raffaele; Audergon, Pauline; Bauer, Moritz, 1987-; Saitou, Mitinori; Hochedlinger, Konrad; Beliveau, Brian J.; Cosma, Maria Pia; Lee, Jeannie T.; Payer, Bernhard (National Academy of Sciences, 2023)

  Reactivation of the inactive X chromosome is a hallmark epigenetic event during reprogramming of mouse female somatic cells to induced pluripotent stem cells (iPSCs). This involves global structural remodeling from a ...
• Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson’s disease

  Alvarez Jerez, Pilar; Alcantud, Jose Luis; Reyes-Ramírez, Lucia de los; Moore, Anni; Ruz, Clara; Vives Montero, Francisco; Rodriguez-Losada, Noela; Saini, Prabhjyot; Gan-Or, Ziv; Alvarado, Chelsea X.; Makarious, Mary B.; Billingsley, Kimberley J.; Blauwendraat, Cornelis; Noyce, Alastair J.; Singleton, Andrew B.; Duran, Raquel; Bandres-Ciga, Sara (Nature Research, 2023)

  Neurodegeneration with brain iron accumulation (NBIA) represents a group of neurodegenerative disorders characterized by abnormal iron accumulation in the brain. In Parkinson's Disease (PD), iron accumulation is a cardinal ...
• Automated optimisation of solubility and conformational stability of antibodies and proteins

  Rosace, Angelo; Bennett, Anja; Oeller, Marc; Mortensen, Mie M.; Sakhnini, Laila; Lorenzen, Nikolai; Poulsen, Christian; Sormanni, Pietro (Nature Research, 2023)

  Biologics, such as antibodies and enzymes, are crucial in research, biotechnology, diagnostics, and therapeutics. Often, biologics with suitable functionality are discovered, but their development is impeded by developability ...
• Robustness and innovation in synthetic genotype networks

  Santos-Moreno, Javier; Tasiudi, Eve; Kusumawardhani, Hadiastri; Stelling, Joerg; Schaerli, Yolanda (Nature Research, 2023)

  Genotype networks are sets of genotypes connected by small mutational changes that share the same phenotype. They facilitate evolutionary innovation by enabling the exploration of different neighborhoods in genotype space. ...
• Natural green spaces, sensitization to allergens, and the role of gut microbiota during infancy

  Buchholz, Vienna; Bridgman, Sarah L.; Nielsen, Charlene C.; Gascon Merlos, Mireia, 1984-; Tun, Hein M.; Simons, Elinor; Turvey, Stuart E.; Subbarao, Padmaja; Takaro, Tim K.; Brook, Jeffrey R.; Scott, James A.; Mandhane, Piush J.; Kozyrskyj, Anita L. (American Society for Microbiology, 2023)

  The environment plays an instrumental role in the developmental origins of health and disease. Protective features of the environment in the development of asthma and atopy have been insufficiently studied. We used data ...
• Analyzing the role of cancer-associated fibroblast activation on macrophage polarization

  Bruch Oms, Marina; Olivera-Salguero, Rubén, 1991-; Mazzolini, Rocco; Valle Pérez, Beatriz del; Mayo González, Paula; Beteta, Ángel; Peña Arranz, Raúl; García de Herreros, Antonio (Wiley, 2023)

  Snail1 is a transcriptional factor required for cancer-associated fibroblast (CAF) activation, and mainly detected in CAFs in human tumors. In the mouse mammary tumor virus-polyoma middle tumor-antigen (MMTV-PyMT) model ...
• Beauveria bassiana rewires molecular mechanisms related to growth and defense in tomato

  Proietti, Silvia; Falconieri, Gaia Salvatore; Bertini, Laura; Pascale, Alberto; Bizzarri, Elisabetta; Morales Sanfrutos, Julia; Sabidó Aguadé, Eduard, 1981-; Ruocco, Michelina; Monti, Maurilia M.; Russo, Assunta; Dziurka, Kinga; Ceci, Marcello; Loreto, Francesco; Caruso, Carla (Oxford University Press, 2023)

  Plant roots can exploit beneficial associations with soil-inhabiting microbes, promoting growth and expanding the immune capacity of the host plant. In this work, we aimed to provide new information on changes occurring ...
• Electronic Cigarette Use in 12 European countries: results from the TackSHS survey

  Gallus, Silvano; Lugo, Alessandra; Stival, Chiara; Cerrai, Sonia; Clancy, Luke; Filippidis, Filippos T.; Gorini, Giuseppe; López, Maria José; López Nicolás, Ángel; Molinaro, Sabrina; Odone, Anna; Soriano, Joan B.; Tigova, Olena; van den Brandt, Piet A.; Vardavas, Constantine; Fernández, Esteve; TackSHS Project Investigators (Japan Epidemiological Association, 2023)

  Background: Limited data on electronic cigarette prevalence, patterns, and settings of use are available from several European countries. Methods: Within the TackSHS project, a face-to-face survey was conducted in 2017-2018 ...
• A longitudinal study of free leptin index in pre-eclamptic pregnancies

  Garcés, María Fernanda; Buell-Acosta, Julieth Daniela; Rodríguez-Navarro, Haiver Antonio; Páez-Leal, María Carolina; Maldonado-Acosta, Luis Miguel; Peralta-Franco, Jhon Jairo; Burgos-Cardenas, Álvaro Javier; Ángel-Müller, Edith; Parada-Baños, Arturo José; Parra-Pineda, Mario Orlando; Eslava-Schmalbach, Javier; Escobar-Sarmiento, Camilo Andrés; Lacunza, Ezequiel; Caminos-Cepeda, Sofia Alexandra; Castaño, Justo P.; Nogueiras, Ruben; Dieguez, Carlos; Ruiz-Parra, Ariel Iván; Caminos, Jorge Eduardo (Wiley, 2023)

  The ratio between circulating levels of leptin and soluble leptin receptor (sOB-R), the free leptin index (FLI), is used as a marker of leptin resistance. Therefore, the aim of our study was to investigate the FLI in mild ...
• Why has epidemiology not (yet) succeeded in identifying the origin of the asthma epidemic?

  Antó i Boqué, Josep Maria; Pearce, Neil E.; Douwes, Jeroen; García Aymerich, Judith; Pembrey, Lucy; Richiardi, Lorenzo; Sunyer Deu, Jordi (Oxford University Press, 2023)
• Protein supplementation in a prehabilitation program in patients undergoing surgery for endometrial cancer

  Sole-Sedeno, Josep M.; Miralpeix, Ester; Muns, Maria Dolors; Rodriguez-Cosmen, Cristina; Fabregó, Berta; Kanjou, Nadwa; Medina, Francesc-Xavier; Mancebo Moreno, Gemma (MDPI, 2023)

  Enhanced recovery after surgery (ERAS) and prehabilitation programs are multidisciplinary care pathways to reduce stress response and improve perioperative outcomes, which also include nutritional interventions. The aim ...
• Association between malnutrition assessed by the global leadership initiative on malnutrition criteria and mortality in older people: a scoping review

  Sánchez-Rodríguez, María Dolores; De Meester, Dorien; Minon, Léa; Claessens, Marie; Gümüs, Neslian; Lieten, Siddhartha; Benoit, Florence; Surquin, Murielle; Marco Navarro, Ester (MDPI, 2023)

  The Global Leadership Initiative on Malnutrition (GLIM) criteria were introduced in 2018 for the diagnosis of malnutrition in adults. This review was aimed at gathering the evidence about the association between malnutrition ...
• A qualitative exploration of patient safety in a hospital setting in Spain: policy and practice recommendations on patients' and companions' participation

  Abiétar, Daniel G.; Domingo, Laia; Medina Perucha, Laura; Saavedra, Nuria; Berenguera, Anna; Lacueva-Pérez, Laia; Hurtado, Marta; Castells, Xavier; Sala, Maria (Wiley, 2023)

  Introduction: Patients' and companions' participation in healthcare could help prevent adverse events, which are a significant cause of disease and disability. Before designing interventions to increase participation, it ...
• Gender inequalities in the prevalence of low mood and related factors in schooled adolescents during the 2019–2020 school year: DESKcohort project

  Gonzalez-Casals, Helena; Vives, Jaume; Bosque Prous, Marina, 1984-; Folch Toda, Cinta; Drou-Roget, Gemma; Muntaner, Carles, 1957-; Vives Cases, Carmen; Barbaglia, María Gabriela, 1979-; Colom, Joan; Espelt Hernández, Albert, 1981- (Elsevier, 2023)

  Background: Mood disorders are the second most prevalent mental disorders in childhood and adolescence. Many undiagnosed people manifest subthreshold symptoms, like low mood, and present worse prognoses than asymptomatic ...

View more