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Articles (Departament de Medicina i Ciències de la Vida)

Articles (Departament de Medicina i Ciències de la Vida)

 

Articles de recerca, en accés obert, del Departament de Medicina i Ciències de la Vidade la UPF.

Recent Submissions

  • Andreu Martínez, David (American Society for Microbiology, 2024)
  • Benavides, Fernando G. (Fernando García) (Associació Catalana de Salut Laboral, 2024)
  • Esteban, Ignasi; Pastor-Quiñones, Carmen; Usero, Lorena; Aurrecoechea, Elena; Franceschini, Lorenzo; Esprit, Arthur; Gelpí, Josep Lluís; Martínez-Jiménez, Francisco; López Bigas, Núria; Breckpot, Karine; Thielemans, Kris; Leal, Lorna; Gómez, Carmen Elena; Sisteré-Oró, Marta; Meyerhans, Andreas; Esteban, Mariano; Alonso Fernández, María José; García, Felipe; Plana, Montserrat; COVARNA Consortium (MDPI, 2023)
    The COVID-19 pandemic has brought significant changes and advances in the field of vaccination, including the implementation and widespread use of encapsidated mRNA vaccines in general healthcare practice. Here, we present ...
  • Kennedy, Keith Endres; García Ojalvo, Jordi; Villoslada, Pablo (Public Library of Science (PLoS), 2024)
    Complex diseases such as Multiple Sclerosis (MS) cover a wide range of biological scales, from genes and proteins to cells and tissues, up to the full organism. In fact, any phenotype for an organism is dictated by the ...
  • Sousa Pinto, Bernardo; Antó i Boqué, Josep Maria; MASK-air think tank (Wiley, 2024)
    Background: In allergic rhinitis and asthma, adolescents and young adult patients are likely to differ from older patients. We compared adolescents, young adults and adults on symptoms, control levels, and medication ...
  • Awamleh, Zain; Choufani, Sanaa; Wu, Wendy; Rots, Dmitrijs; Dingemans, Alexander J. M.; Nadif Kasri, Nael; Boronat i Llop, Susanna, 1965-; Ibáñez-Micó, Salvador; Cuesta Herraiz, Laura; Ferrer, Irene; Martínez Carrascal, Antonio; Pérez Jurado, Luis Alberto; Aznar Laín, Gemma; Ortigoza Escobar, Juan Darío; de Vries, Bert B. A.; Koolen, David A.; Weksberg, Rosanna (Nature Research, 2024)
    Pathogenic variants in KANSL1 and 17q21.31 microdeletions are causative of Koolen-de Vries syndrome (KdVS), a neurodevelopmental syndrome with characteristic facial dysmorphia. Our previous work has shown that syndromic ...
  • Pérez Jurado, Luis Alberto; Cáceres, Alejandro; Balagué-Dobón, Laura; Esko, Tõnu; López de Heredia, Miguel de; Quintela Garcia, Ines; Cruz, Raquel; Lapunzina, Pablo Daniel; Carracedo, Ángel; SCOURGE Cohort Group; González, Juan Ramón (Nature Research, 2024)
    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially ...
  • Sarkar, Soumyadeep; Ramos-Rodríguez, Mireia; Juan-Mateu, Jonàs; Pasquali, Lorenzo; Nakayasu, Ernesto S. (BioMed Central, 2024)
    Background: Lipids are regulators of insulitis and β-cell death in type 1 diabetes development, but the underlying mechanisms are poorly understood. Here, we investigated how the islet lipid composition and downstream ...
  • Carreras-Mora, José; Simón-Ramón, Clara; Vidal Burdeus, María; Rodríguez Sotelo, Laura; Sionis, Alessandro; Giralt Borrell, Teresa; Izquierdo-Marquisá, Andrea; Rodríguez González, Clara; Farré López, Núria; Cainzos-Achirica, Miguel; Tizón-Marcos, Helena; Garcia-Picart, Joan; Milà Pascual, Laia; Vaquerizo Montilla, Beatriz; Rivas-Lasarte, Mercedes; Ribas Barquet, Núria (BMJ Publishing Group, 2023)
    Objective: We evaluated the prognostic value of subclinical congestion assessed by lung ultrasound (LUS) in patients admitted for ST segment elevation myocardial infarction (STEMI). Methods: This was a multicentre study ...
  • Lucas-Sánchez, Marcel; Abdeli, Amine; Bekada, Asmahan; Calafell i Majó, Francesc; Benhassine, Traki; Comas, David, 1969- (Oxford University Press, 2024)
    The strategic location of North Africa has made the region the core of a wide range of human demographic events, including migrations, bottlenecks, and admixture processes. This has led to a complex and heterogeneous genetic ...
  • Sisteré-Oró, Marta; Du, Juan; Wortmann, Diana D. J.; Filippi, Marina D.; Cañas-Ruano, Esperanza; Arrieta Aldea, Itziar; Marcos-Blanco, Agustín; Castells, Xavier; Grau Cerrato, Santiago; García-Giralt, Natalia; Perez-Zsolt, Daniel; Boreika, Rytis; Izquierdo-Useros, Nuria; Güerri Fernández, Roberto; Meyerhans, Andreas (Wiley, 2024)
    People living with human immunodeficiency virus (HIV) are the individuals most affected by the current Monkeypox virus outbreak that was first announced in May 2022. Here we report Pan-pox-specific T-cell responses in a ...
  • Santana-Hernández, Sara; Suárez Olmos, Jesús; Servitja Tormo, Sonia; Berenguer-Molins, Pau; Costa García, Marcel, 1989-; Comerma Blesa, Laura, 1983-; Rea, Anna; Perera Bel, Júlia; Menendez Romero, Silvia; Arpí Llucià, Oriol; Bermejo, Begoña; Martínez, María Teresa; Cejalvo, Juan Miguel; Comino-Méndez, Iñaki; Pascual, Javier; Alba, Emilio; López-Botet, M. (Miguel); Rojo, Federico; Rovira, Ana; Albanell Mestres, Joan; Muntasell i Castellví, Aura, 1972- (BioMed Central, 2024)
    Background: The variability in responses to neoadjuvant treatment with anti-HER2 antibodies prompts to personalized clinical management and the development of innovative treatment strategies. Tumor-infiltrating Natural ...
  • Papaleo, Natalia; Climent, Fina; Tapia, Gustavo; Luizaga Velasco, Luis; Azcarate, Juan; Bosch-Schips, Jan; Muñoz-Mármol, Ana M.; Salido Galeote, Marta; Lome-Maldonado, Carmen; Vázquez, Ivonne; Colomo Saperas, Luis Alberto (Springer, 2023)
    Aggressive large B-cell lymphomas (aLBCL) include a heterogeneous group of lymphomas with diverse biological features. One of the approaches to the diagnosis of aLBCL is based on the identification of MYC rearrangements ...
  • Sabanés Zariquiey, Francesc; Galvelis, Raimondas; Gallicchio, Emilio; Chodera, John D.; Markland, Thomas E.; De Fabritiis, Gianni (American Chemical Society (ACS), 2024)
    This letter gives results on improving protein-ligand binding affinity predictions based on molecular dynamics simulations using machine learning potentials with a hybrid neural network potential and molecular mechanics ...
  • Zhou, Chengzhi; Barreiro Portela, Esther; Chen, Rongchang (AME Publishing, 2023)
    Background: Lung cancer combined by chronic obstructive pulmonary disease (LC-COPD) is a common comorbidity and their interaction with each other poses significant clinical challenges. However, there is a lack of ...
  • Galvelis, Raimondas; Varela-Rial, Alejandro; Doerr, Stefan, 1987-; Fino, Roberto; Eastman, Peter; Markland, Thomas E.; Chodera, John D.; De Fabritiis, Gianni (American Chemical Society (ACS), 2023)
    Machine learning potentials have emerged as a means to enhance the accuracy of biomolecular simulations. However, their application is constrained by the significant computational cost arising from the vast number of ...
  • Sabanés Zariquiey, Francesc; Pérez, Adrià; Majewski, Maciej; Gallicchio, Emilio; De Fabritiis, Gianni (American Chemical Society (ACS), 2023)
    The accurate prediction of protein-ligand binding affinities is crucial for drug discovery. Alchemical free energy calculations have become a popular tool for this purpose. However, the accuracy and reliability of these ...
  • Achebak, Hicham; García Aymerich, Judith; Rey, Grégoire; Chen, Zhaoyue; Méndez Turrubiates, Raúl Fernando; Ballester, Joan (Elsevier, 2023)
    Background: The seasonal fluctuation in mortality and hospital admissions from respiratory diseases, with a winter peak and a summer trough, is widely recognized in extratropical countries. However, little is known about ...
  • Boll, Lilian Marie; Perera Bel, Júlia; Rodriguez-Vida, Alejo; Arpí Llucià, Oriol; Rovira, Ana; Juanpere, Nuria; Vázquez Montes de Oca, Sergio; Hernández Llodrà, Silvia; Lloreta Trull, Josep, 1958-; Albà Soler, Mar; Bellmunt Molins, Joaquim, 1959- (Nature Research, 2023)
    Immune checkpoint inhibitors (ICI) have revolutionized cancer treatment and can result in complete remissions even at advanced stages of the disease. However, only a small fraction of patients respond to the treatment. To ...
  • Sinigaglia, Barbara; Escudero, Jorge; Biagini, Simone Andrea, 1983-; García Calleja, Jorge; Moreno, Josep; Dobón Berenguer, Begoña, 1987-; Acosta, Sandra; Mondal, Mayukh, 1989-; Walsh Capdevila, Sandra, 1991-; Aguileta, Gabriela; Vallès, Mònica; Forrow, Stephen; Martín Caballero, Juan; Migliano, Andrea Bamberg; Bertranpetit, Jaume, 1952-; Muñoz López, Francisco José, 1964-; Bosch Fusté, Elena (Oxford University Press, 2024)
    Rainforest hunter-gatherers from Southeast Asia are characterized by specific morphological features including a particularly dark skin color (D), short stature (S), woolly hair (W), and the presence of steatopygia (S)-fat ...

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