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Articles (Departament de Ciències Experimentals i de la Salut)

Articles (Departament de Ciències Experimentals i de la Salut)

 

Articles de recerca, en accés obert, del Departament de Ciències Experimentals i de la Salut de la UPF.

Recent Submissions

  • Forner, Mar; Cañas Arranz, Rodrigo; Defaus, Sira; de León, Patricia; Rodríguez Pulido, Miguel; Ganges, Lliliane; Blanco, Esther; Sobrino, Francisco; Andreu Martínez, David (MDPI, 2021)
    Vaccines are considered one of the greatest global health achievements, improving the welfare of society by saving lives and substantially reducing the burden of infectious diseases. However, few vaccines are fully effective, ...
  • Solís Moruno, Manuel; Mensa Vilaró, Anna; Batlle Masó, Laura, 1993-; Lobón, Irene; Bonet, Núria; Marquès i Bonet, Tomàs, 1975-; Aróstegui, Juan Ignacio; Casals López, Ferran (Nature Research, 2021)
    There are increasing evidences showing the contribution of somatic genetic variants to non-cancer diseases. However, their detection using massive parallel sequencing methods still has important limitations. In addition, ...
  • Serra, Selma A.; Stojakovic, Predrag; Amat, Ramon; Rubio Moscardó, Fanny; Latorre Doménech, Pablo, 1993-; Seisenbacher, Gerhard; Canadell, David; Böttcher, René; Aregger, Michael; Moffat, Jason; Nadal Clanchet, Eulàlia de; Valverde, M. A. (Miguel Ángel), 1963-; Posas Garriga, Francesc (National Academy of Sciences, 2021)
    Regulation of cell volume is essential for tissue homeostasis and cell viability. In response to hypertonic stress, cells need rapid electrolyte influx to compensate water loss and to prevent cell death in a process known ...
  • García Pérez, Raquel, 1989-; Esteller-Cucala, Paula; Mas, Glòria; Lobón, Irene; Di Carlo, Valerio; Riera, Meritxell; Kuhlwilm, Martin; Navarro i Cuartiellas, Arcadi, 1969-; Blancher, Antoine; Di Croce, Luciano; Gómez Skarmeta, José Luis; Juan, David; Marquès i Bonet, Tomàs, 1975- (Nature Research, 2021)
    Changes in the epigenetic regulation of gene expression have a central role in evolution. Here, we extensively profiled a panel of human, chimpanzee, gorilla, orangutan, and macaque lymphoblastoid cell lines (LCLs), using ...
  • Westbury, Michael V.; Barnett, Ross; Sandoval Velasco, Marcela; Gower, Graham; Garrett Vieira, Filipe; Manuel Montero, Marc de, 1991-; Hansen, Anders J.; Yamaguchi, Nobuyuki; Werdelin, Lars; Marquès i Bonet, Tomàs, 1975-; Gilbert, M Thomas; Lorenzen, Eline D. (UNLISTED PUBLISHER, 2021)
    Background: The evolutionary relationships of Felidae during their Early–Middle Miocene radiation is contentious. Although the early common ancestors have been subsumed under the grade-group Pseudaelurus, this group is ...
  • Cañizo, Carlos del; Cristóbal, Ana Belén; Barbosa, Luisa; Revuelta, Gema; Haas, Sabine; Victoria, Marta; Brocklehurst, Martin (Open Research Europe, 2021)
    Citizen science is becoming an effective approach in building a new relationship between science and society, in which the desire of citizens to participate actively in knowledge production meets the needs of researchers. ...
  • Ramada Rodilla, José María, 1961-; Calvo Cerrada, Beatriz; Serra, Consol; Delclos, George L.; Benavides, Fernando G. (Fernando García) (Elsevier, 2021)
    Objective: What are the levels of asbestos exposure that cause each type of health effect? The objective of this study was to review the available scientific evidence on exposure levels for asbestos and their relationship ...
  • Shirvani Farsani, Zeinab; Maloum, Zahra; Bagheri Hosseinabadi, Zahra; Vilor Tejedor, Natàlia, 1988-; Sadeghi, Iman; Sadeghi, Iman (Elsevier, 2021)
    DNA methylation is a broadly-investigated epigenetic modification that has been considered as a heritable and reversible change. Previous findings have indicated that DNA methylation regulates gene expression in the central ...
  • Liu, Huanle; Begik, Oguzhan; Novoa, Eva Maria (Springer, 2021)
    RNA modifications play pivotal roles in the RNA life cycle and RNA fate, and are now appreciated as a major posttranscriptional regulatory layer in the cell. In the last few years, direct RNA nanopore sequencing (dRNA-seq) ...
  • García Montolío, Marc, 1991-; Ballaré, Cecilia Julia; Blanco, Enrique; Gutiérrez, Arantxa; Aranda Aragón, Sergio; Gómez, Antonio; Kok, Chung H.; Yeung, David T.; Hughes, Timothy P.; Vizán, Pedro; Di Croce, Luciano (Frontiers Media, 2021)
    Polycomb group (PcG) of proteins are a group of highly conserved epigenetic regulators involved in many biological functions, such as embryonic development, cell proliferation, and adult stem cell determination. PHD finger ...
  • Chiva, Cristina; Mendes Maja, Teresa; Panse, Christian; Stejskal, Karel; Douché, Thibaut; Matondo, Mariette; Loew, Darmarys; Helm, Dominic; Rettel, Mandy; Mechtler, Karl; Impens, Francis; Nanni, Paolo; Shevchenko, Anna; Sabidó Aguadé, Eduard, 1981- (EMBO Press, 2021)
    Proteomics research infrastructures and core facilities within the Core for Life alliance advocate for community policies for quality control to ensure high standards in proteomics services.
  • Esteve-Codina, Anna; Nadal, Anna; Zagorščak, Maja; Ramšak, Živa; Esteve-Codina, Anna; Gruden, Kristina; Pla, Maria (BioMed Central, 2021)
    Background: Rosaceae species are economically highly relevant crops. Their cultivation systems are constrained by phytopathogens causing severe losses. Plants respond to invading pathogens through signaling mechanisms, a ...
  • Jiménez, Isabel; Tazón-Vega, Bárbara; Abrisqueta, Pau; Nieto, Juan C.; Bobillo, Sabela; Palacio-García, Carles; Carabia, Júlia; Valdés-Mas, Rafael; Munuera, Magdalena; Puigdefàbregas, Lluís; Parra Farré, Genís; Esteve-Codina, Anna; Franco-Jarava, Clara; Iacoboni, Gloria; Terol, María-José; García-Marco, J. A.; Crespo Barrio, Marta; Bosch, Francesc (BioMed Central, 2021)
    Background: Mechanisms driving the progression of chronic lymphocytic leukemia (CLL) from its early stages are not fully understood. The acquisition of molecular changes at the time of progression has been observed in a ...
  • Gómez-Gómez, Àlex; Montero-San-Martin, Blanca; Haro, Noemí; Pozo Mendoza, Óscar J. (MDPI, 2021)
    Melatonin plays multiple physiological roles in the human body. Evaluation of melatonin production by the determination of urinary 6-sulfatoxymelatonin in 24-h samples has important drawbacks which hinder the successful ...
  • Calvo Serra, Beatriz; Maitre, Léa; Lau, Chung-Ho E.; Siskos, Alexandros P.; Gützkow, Kristine B.; Andrušaitytė, Sandra; Casas Sanahuja, Maribel; Cadiou, Solène; Chatzi, Leda; González, Juan Ramón; Grazuleviciene, Regina; McEachan, Rosemary R.C.; Slama, Rémy; Vafeiadi, Marina, 1983-; Wright, John; Coen, Muireann; Vrijheid, Martine; Keun, Hector C.; Escaramís, Geòrgia; Bustamante Pineda, Mariona (Oxford University Press, 2021)
    Human metabolism is influenced by genetic and environmental factors. Previous studies have identified over 23 loci associated with more than 26 urine metabolites levels in adults, which are known as urinary metabolite ...
  • Prado Bert, Paula de; Ruiz Arenas, Carlos, 1990-; Vives Usano, Marta, 1990-; Dadvand, Payam; González, Juan Ramón; Maitre, Léa; Nieuwenhuijsen, Mark J.; Pelegrí, Dolors; Sunyer Deu, Jordi; Vrijheid, Martine; Bustamante Pineda, Mariona (Elsevier, 2021)
    The early-life exposome influences future health and accelerated biological aging has been proposed as one of the underlying biological mechanisms. We investigated the association between more than 100 exposures assessed ...
  • Tenorio Castaño, Jair; Pérez Jurado, Luis Alberto; Lapunzina, Pablo Daniel (MDPI, 2021)
    Schuurs-Hoeijmakers syndrome (SHMS) or PACS1 Neurodevelopmental disorder is a rare disorder characterized by intellectual disability, abnormal craniofacial features and congenital malformations. SHMS is an autosomal dominant ...
  • Ciampa, Iacopo; Operto, Grégory; Falcón, Carles; Minguillón, Carolina; Castro de Moura, Manuel; Piñeyro, David; Esteller, Manel; Molinuevo, José Luis; Guigó Serra, Roderic; Navarro i Cuartiellas, Arcadi, 1969-; Gispert López, Juan Domingo; Vilor Tejedor, Natàlia, 1988-; ALFA Study (MDPI, 2021)
    This study investigated whether genetic factors involved in Alzheimer's disease (AD) are associated with enlargement of Perivascular Spaces (ePVS) in the brain. A total of 680 participants with T2-weighted MRI scans and ...
  • Artazcoz Lazcano, Lucía, 1963-; Cortès-Franch, Imma; Escribà-Agüir, Vicenta; Benavides, Fernando G. (Fernando García) (Frontiers, 2021)
    Objectives: Although in-work poverty has been increasing, in Europe policy about poverty and social exclusion tends to focus on labor market participation, independently of the level of remuneration and the quality of work, ...
  • Durán Alonso, Beatriz; Vendrell, Víctor; López Hernández, Iris; Alonso Pérez, María Teresa; Martin, Donna M.; Giráldez, Fernando; Carramolino, Laura; Giovinazzo, Giovanna; Vázquez, Enrique; Torres, Miguel S.; Schimmang, Thomas (Frontiers, 2021)
    Meis genes have been shown to control essential processes during development of the central and peripheral nervous system. Here we have explored the roles of the Meis2 gene during vertebrate inner ear induction and the ...

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