• Exploring the influence of circulating endocannabinoids and nucleus accumbens functional connectivity on anorexia nervosa severity

  Miranda-Olivos, Romina; Baenas, Isabel; Steward, Trevor; Granero, Roser; Pastor, Antonio; Sánchez, Isabel; Juaneda-Seguí, Asier; Pino-Gutiérrez, Amparo del; Fernández-Formoso, José A.; Vilarrasa, Nuria; Guerrero-Pérez, Fernando; Virgili, Núria; López-Urdiales, Rafael; Jiménez Murcia, Susana; Torre Fornell, Rafael de la; Soriano Mas, Carles; Fernández Aranda, Fernando (Nature Research, 2023)

  Anorexia nervosa (AN) is a severe psychiatric disorder characterized by a harmful persistence of self-imposed starvation resulting in significant weight loss. Research suggests that alterations in the nucleus accumbens ...
• Consensus on post COVID in the Spanish national health system: Results of the CIBERPOSTCOVID eDelphi study

  Torres, Marta; Serra-Sutton, Vicky; Soriano, Joan B.; Ferrer Forés, Maria Montserrat; Trejo, Alex; Benavides, Fernando G. (Fernando García); Lumbreras, Blanca; Pérez-Gómez, Beatriz; Pijoán, José Ignacio; Monguet, Josep M.; Barbé, Ferran; Pollán, Marina; Alonso Caballero, Jordi; Espallargues, Mireia; Serrano-Blanco, Antoni (Elsevier, 2023)

  Background: In 2021, the Spanish Ministry of Health launched the CIBERPOSTCOVID project to establish what post COVID was. The present study reports the level of agreement among stakeholders on post COVID and its clinical ...
• Single-cell Bayesian deconvolution

  Torregrosa-Cortés, Gabriel; Oriola, David; Trivedi, Vikas; García Ojalvo, Jordi (Elsevier, 2023)

  Individual cells exhibit substantial heterogeneity in protein abundance and activity, which is frequently reflected in broad distributions of fluorescently labeled reporters. Since all cellular components are intrinsically ...
• A fast non-parametric test of association for multiple traits

  Garrido Martín, Diego, 1992-; Calvo, Miquel (Calvo Llorca); Reverter, Ferran; Guigó Serra, Roderic (BioMed Central, 2023)

  The increasing availability of multidimensional phenotypic data in large cohorts of genotyped individuals requires efficient methods to identify genetic effects on multiple traits. Permutational multivariate analysis of ...
• A new assemblage of late Neanderthal remains from Cova Simanya (NE Iberia)

  Morales, Juan I.; Cebrià, Artur; Soto, María; Rodríguez-Hidalgo, Antonio; Hernando, Raquel; Moreno-Ribas, Elena; Lombao, Diego; Rabuñal, José R.; Martín-Perea, David M.; García-Tabernero, Antonio; Allué, Ethel; García Basanta, Andrea; Lizano González, Esther, 1974-; Marquès i Bonet, Tomàs, 1975-; Talamo, Sahra; Tassoni, Laura; Lalueza Fox, Carles, 1965-; Fullola, Josep M.; Rosas, Antonio (Frontiers, 2023)

  This study presents an exceptional collection of 54 Late Pleistocene human remains that correspond to at least three Neanderthal individuals from Simanya Gran, the main gallery of Cova Simanya, located in the northeastern ...
• Increased paclitaxel recovery from Taxus baccata vascular stem cells using novel in situ product recovery approaches

  Santoyo-Garcia, Jorge H.; Valdivia-Cabrera, Marissa; Ochoa-Villarreal, Marisol; Casasola-Zamora, Samuel; Ripoll, Magdalena; Escrich Montañana, Ainoa; Moyano Claramunt, Elisabet; Betancor, Lorena; Halliday, Karen J.; Loake, Gary J.; Rios-Solis, Leonardo (Springer, 2023)

  In this study, several approaches were tested to optimise the production and recovery of the widely used anticancer drug Taxol® (paclitaxel) from culturable vascular stem cells (VSCs) of Taxus baccata, which is currently ...
• Classification system for nanotechnology-enabled health products with both scientific and regulatory application

  Rodríguez-Gómez, Francisco D.; Penon, Oriol; Monferrer, Dominique; Rivera Gil, Pilar, 1976- (Frontiers, 2023)

  The lack of specific regulatory guidelines for nanotechnology-enabled health products (NHPs) is hampering development and patient access to these innovative technologies. Namely, there is an urgent need for harmonized ...
• Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

  Maury, Eduardo A.; Brain Somatic Mosaicism Network; Walsh, Christopher A. (Elsevier, 2023)

  While germline copy-number variants (CNVs) contribute to schizophrenia (SCZ) risk, the contribution of somatic CNVs (sCNVs)-present in some but not all cells-remains unknown. We identified sCNVs using blood-derived genotype ...
• A quantitative systems pharmacology model for certolizumab pegol treatment in moderate-to-severe psoriasis

  Coto-Segura, Pablo; Segú-Vergés, Cristina; Martorell, Antonio; Moreno-Ramírez, David; Jorba Argemí, Guillem; Junet, Valentin; Guerri, Filippo; Daura, Xavier; Oliva Miguel, Baldomero; Cara, Carlos; Suárez-Magdalena, Olaya; Abraham, Sonya; Mas, José Manuel (Frontiers, 2023)

  Background: Psoriasis is a chronic immune-mediated inflammatory systemic disease with skin manifestations characterized by erythematous, scaly, itchy and/or painful plaques resulting from hyperproliferation of keratinocytes. ...
• Influenza vaccination coverage rates and determinants in Greek children until the age of ten (2008-2019), the Rhea mother-child cohort

  Karachaliou, Marianna; Damianaki, Irene; Moudatsaki, Maria; Margetaki, Katerina; Roumeliotaki, Theano; Bempi, Vicky; Moudatsaki, Marina; Chatzi, Lida Vaia; Vafeiadi, Marina, 1983-; Kogevinas, Manolis (MDPI, 2023)

  Background: In Greece, influenza vaccination is currently recommended for children with high-risk conditions. There are limited data on influenza vaccination uptake among Greek children with and without high-risk conditions. ...
• Approaching unsafe limits: climate-related health inequities within and beyond Europe

  Daalen, Kim van; Tonne, Cathryn; Borrell i Thió, Carme; Nilsson, Maria; Lowe, Rachel (Elsevier, 2023)
• Spatial and sector-specific contributions of emissions to ambient air pollution and mortality in European cities: a health impact assessment

  Khomenko, Sasha; Pisoni, Enrico; Thunis, Philippe; Bessagnet, Bertrand; Cirach, Marta; Iungman, Tamara; Pereira Barboza, Evelise; Khreis, Haneen; Mueller, Natalie, 1988-; Tonne, Cathryn; Hoogh, Kees de; Hoek, Gerard; Chowdhury, Sourangsu; Lelieveld, Jos; Nieuwenhuijsen, Mark J. (Elsevier, 2023)

  Background: Ambient air pollution is a major risk to health and wellbeing in European cities. We aimed to estimate spatial and sector-specific contributions of emissions to ambient air pollution and evaluate the effects ...
• Health benefits of Open Streets programmes in Latin America: a quantitative health impact assessment

  Velázquez-Cortés, Daniel; Nieuwenhuijsen, Mark J.; Jerrett, Michael; Rojas Rueda, David, 1979- (Elsevier, 2023)

  Background: To improve physical activity in Latin American cities, several interventions have been promoted, such as Open Streets programmes. Our study aims to quantify the health and economic effects of Open Streets-related ...
• Montelukast in paediatric asthma and allergic rhinitis: a systematic review and meta-analysis

  Mayoral, Karina; Lizano-Barrantes, Catalina; Zamora, Víctor; Pont Acuña, Àngels; Miret, Carme; Barrufet González, Cristina; Caballero-Rabasco, María Araceli; Praena-Crespo, Manuel; Bercedo, Alberto; Valdesoiro-Navarrete, Laura; Guerra, María Teresa; Pardo Cladellas, Yolanda; Martínez Zapata, María José; Garin Boronat, Olatz, 1979-; Ferrer Forés, Maria Montserrat; ARCA Group (European Respiratory Society, 2023)

  Background: We aim to assess the impact of montelukast on paediatric patients with asthma/allergic rhinitis, measured using patient-reported outcome measures, compared with other treatments or placebo. Methods: Protocol ...
• Impact of histone H4K16 acetylation on the meiotic recombination checkpoint in Saccharomyces cerevisiae

  Cavero, Santiago; Herruzo, Esther; Ontoso, David; San-Segundo, Pedro A. (Shared Science Publishers OG, 2016)

  In meiotic cells, the pachytene checkpoint or meiotic recombination checkpoint is a surveillance mechanism that monitors critical processes, such as recombination and chromosome synapsis, which are essential for proper ...
• The RanGTP pathway: from nucleo-cytoplasmic transport to spindle assembly and beyond

  Cavazza, Tommaso, 1985-; Vernos, Isabelle, 1959- (Frontiers, 2016)

  The small GTPase Ran regulates the interaction of transport receptors with a number of cellular cargo proteins. The high affinity binding of the GTP-bound form of Ran to import receptors promotes cargo release, whereas its ...
• Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status

  Kim, Kyeezu; Joyce, Brian T.; Nannini, Drew R.; Zheng, Yinan; Gordon-Larsen, Penny; Shikany, James M.; Lloyd-Jones, Donald M.; Hu, Ming; Nieuwenhuijsen, Mark J.; Vaughan, Douglas E.; Zhang, Kai; Hou, Lifang (American Association for the Advancement of Science (AAAS), 2023)

  Slower epigenetic aging is associated with exposure to green space (greenness); however, the longitudinal relationship has not been well studied, particularly in minority groups. We investigated the association between ...
• Urinary metabolomic profile of youth at risk of chronic kidney disease in Nicaragua

  Hall, Samantha M.; Raines, Nathan H.; Ramirez Rubio, Oriana; Amador, Juan José; López-Pilarte, Damaris; O'Callaghan-Gordo, Cristina; Gil-Redondo, Rubén; Embade, Nieves; Millet, Oscar; Peng, Xiaojing; Vences, Selene; Keogh, Sinead A.; Delgado, Iris; Friedman, David J.; Brooks, Daniel R.; Leibler, Jessica H. (Wolters Kluwer (LWW), 2023)

  Background: CKD of a nontraditional etiology (CKDnt) is responsible for high mortality in Central America, although its causes remain unclear. Evidence of kidney dysfunction has been observed among youth, suggesting that ...
• Health-related quality of life and adherence to physical activity and screen time recommendations in schoolchildren: Longitudinal cohort Ciao Corona

  Haile, Sarah R.; Gunz, Samuel; Peralta, Gabriela P.; Ulyte, Agne; Raineri, Alessia; Rueegg, Sonja; Yasenok, Viktoriia; Radtke, Thomas; Puhan, Milo A.; Kriemler, Susi (Frontiers, 2023)

  Objectives: We investigated changes in adherence to physical activity (PA) and screen time (ST) recommendations of children and adolescents throughout the pandemic, and their association with health-related quality of life ...
• Firefighters and the liver: Exposure to PFAS and PAHs in relation to liver function and serum lipids (CELSPAC-FIREexpo study)

  Pálešová, Nina; Maitre, Léa; Stratakis, Nikos; Řiháčková, Katarína; Pindur, Aleš; Kohoutek, Jir̂í; Šenk, Petr; Bartošková Polcrová, Anna; Gregor, Petr; Vrijheid, Martine; Čupr, Pavel (Elsevier, 2023)

  Introduction: Firefighting is one of the most hazardous occupations due to exposure to per- and polyfluoroalkyl substances (PFAS) and polycyclic aromatic hydrocarbons (PAHs). Such exposure is suspected to affect the ...

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