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Articles (Departament de Medicina i Ciències de la Vida)

Articles (Departament de Medicina i Ciències de la Vida)

 

Articles de recerca, en accés obert, del Departament de Medicina i Ciències de la Vidade la UPF.

Recent Submissions

  • Pérez Ortín, José E.; Jordán Pla, Antonio; Zang, Yujie; Moreno García, Jorge; Bassot, Claudio; Barba Aliaga, Marina; Campos Mata, Leire de, 1991-; Choder, Mordechai; Díez Antón, Juana, 1962-; Piazza, Ilaria; Pelechano, Vicent; García Martínez, José (Wiley, 2024)
    The yeast Saccharomyces cerevisiae and most eukaryotes carry two 5' → 3' exoribonuclease paralogs. In yeast, they are called Xrn1, which shuttles between the nucleus and the cytoplasm, and executes major cytoplasmic messenger ...
  • Farré, Xavier; Blay, Natalia; Espinosa Díaz, Ana; Castaño Vinyals, Gemma; Carreras, Anna; García Aymerich, Judith; Cardis, Elisabeth; Kogevinas, Manolis; Goldberg, Ximena; Cid Ibeas, Rafael de (Nature Research, 2024)
    Risk of depression increased in the general population after the COVID-19 pandemic outbreak. By examining the interplay between genetics and individual environmental exposures during the COVID-19 lockdown, we have been ...
  • Borao Arriazu, Sonia, 1993-; Vega, Montserrat; Boronat i Llop, Susanna, 1965-; Hidalgo Hernando, Elena; Hümmer, Stefan; Ayté del Olmo, José (Public Library of Science (PLoS), 2024)
    Splicing is an important step of gene expression regulation in eukaryotes, as there are many mRNA precursors that can be alternatively spliced in different tissues, at different cell cycle phases or under different external ...
  • Cárdenas Quesada, Jose; Mestre-Pintó, Juan Ignacio; Maldonado, Rafael, 1961-; Rodríguez de Fonseca, Fernando; Torrens, Marta; Farré Albaladejo, Magí (Elsevier, 2024)
    Substance use disorders (SUD), also named addiction when it is severe, is a chronic brain disorder with serious impact on individual who suffer, the public health and with high burden of disease. They are multitude of ...
  • Alvarado-Tapias, Edilmar; Irimia Martínez, Manuel; Gahete, Manuel D. (Elsevier, 2024)
  • Benavides, Fernando G. (Fernando García); Utzet Sadurní, Mireia; Serra, Consol; Delano, Pia; García Gómez, Montserrat; Ayala García, Amaya; Delclòs i Clanchet, Jordi, 1956-; Ronda-Pérez, Elena; García, Vega; García, Ana María (Elsevier, 2024)
    Definimos como personal sanitario a las personas que trabajan en actividades sanitarias, tengan contacto directo o no con los ciudadanos. En la actualidad, alrededor de 1,3 millones de personas (70% mujeres) trabajan en ...
  • Soldevila-Domenech, Natalia; Fagundo, Beatriz; Cuenca Royo, Aida Ma, 1981-; Forcano, Laura; Gomis González, Maria, 1988-; Boronat Rigol, Anna, 1990-; Pastor, Antonio; Castañer, Olga; Zomeño Fajardo, Maria Dolores; Goday Arno, Alberto; Dierssen, Mara; Baghizadeh Hosseini, Khashayar; Ros, Emilio; Corella, Dolores; Martínez-González, Miguel A.; Salas Salvadó, Jordi; Fernández Aranda, Fernando; Fitó Colomer, Montserrat; Torre Fornell, Rafael de la (BioMed Central, 2024)
    Background: The Mediterranean diet (MedDiet) has demonstrated efficacy in preventing age-related cognitive decline and modulating plasma concentrations of endocannabinoids (eCBs) and N-acylethanolamines (NAEs, or eCB-like ...
  • Puerto, Marta; Shukla, Mamta; Bujosa, Paula; Pérez Roldán, Juan; Torràs Llort, Mònica; Tamirisa, Srividya; Carbonell, Albert; Solé, Carme; Puspo, Joynob Akter; Cummings, Christopher; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc; Azorín Marín, Fernando; Rowley, M. Jordan (Oxford University Press, 2024)
    Chromosome pairing constitutes an important level of genome organization, yet the mechanisms that regulate pairing in somatic cells and the impact on 3D chromatin organization are still poorly understood. Here, we address ...
  • Rodríguez-Fernández, Blanca; Sánchez Benavides, Gonzalo; Genius, Patricia; Minguillón, Carolina; Fauria, Karine; De Vivo, Immaculata; Navarro i Cuartiellas, Arcadi, 1969-; Molinuevo, José Luis; Gispert López, Juan Domingo; Sala Vila, Aleix; Vilor Tejedor, Natàlia, 1988-; Crous-Bou, Marta; ALFA Study (Elsevier, 2024)
    Introduction: Leukocyte telomere length (LTL) is an objective biomarker of biological aging, and it is proposed to play a crucial role in Alzheimer's disease (AD) risk. We aimed at evaluating the cross-sectional association ...
  • Pardo Palacios, Francisco J.; Carbonell Sala, Silvia; Lagarde, Julien; Guigó Serra, Roderic; Brooks, Angela N. (Nature Research, 2024)
    The Long-read RNA-Seq Genome Annotation Assessment Project Consortium was formed to evaluate the effectiveness of long-read approaches for transcriptome analysis. Using different protocols and sequencing platforms, the ...
  • Kossatz de Mello, Elk, 1977-; Diez Alarcia, Rebeca; Gaitonde, Supriya A.; Ramon Duaso, Carla, 1987-; Stepniewski, Tomasz Maciej, 1988-; Aranda García, David; Muneta Arrate, Itziar; Tepaz, Elodie; Saen-Oon, Suwipa; Soliva, Robert; Shahraki, Aida; Moreira, David; Brea, José; Loza, María I.; Torre Fornell, Rafael de la; Kolb, Peter; Bouvier, Michel; Meana, J. Javier; Robledo, Patricia, 1958-; Selent, Jana (Nature Research, 2024)
    G protein-coupled receptors (GPCRs) are sophisticated signaling machines able to simultaneously elicit multiple intracellular signaling pathways upon activation. Complete (in)activation of all pathways can be counterproductive ...
  • Grau Bové, Xavier; Subirana, Lucie; Meister, Lydvina; Soubigou, Anaël; Neto, Ana; Elek, Anamaria; Naranjo, Silvia; Fornas Carreño, Oscar; Gómez Skarmeta, José Luis; Tena, Juan J.; Irimia Martínez, Manuel; Bertrand, Stéphanie; Sebé-Pedrós, Arnau; Escriva, Hector (Nature Research, 2024)
    The emergence of new structures can often be linked to the evolution of novel cell types that follows the rewiring of developmental gene regulatory subnetworks. Vertebrates are characterized by a complex body plan compared ...
  • Anderson, Craig J.; López Bigas, Núria; Taylor, Martin S. (Nature Research, 2024)
    DNA base damage is a major source of oncogenic mutations1. Such damage can produce strand-phased mutation patterns and multiallelic variation through the process of lesion segregation2. Here we exploited these properties ...
  • Shields, Ryan K.; Horcajada Gallego, Juan Pablo; Kamat, Shweta; Irani, Paurus M.; Tawadrous, Margaret; Welte, Tobias (Springer, 2024)
    Introduction: Ceftazidime-avibactam (CAZ-AVI) is a combination of the third-generation cephalosporin ceftazidime and the novel, non-β-lactam β-lactamase inhibitor avibactam that is approved for the treatment of pediatric ...
  • Schrade, Lisa; Mah, Nancy; Bandrowski, Anita; Chen, Ying; Dewender, Johannes; Diecke, Sebastian; Hiepen, Christian; Lancaster, Madeline A.; Marquès i Bonet, Tomàs, 1975-; Martínez, Sira; Mueller, Sabine C.; Navara, Christopher; Prigione, Alessandro; Seltmann, Stefanie; Sochacki, Jaroslaw; Sutcliffe, Magdalena A.; Zywitza, Vera; Hildebrandt, Thomas B.; Kurtz, Andreas (MDPI, 2024)
    The documentation, preservation and rescue of biological diversity increasingly uses living biological samples. Persistent associations between species, biosamples, such as tissues and cell lines, and the accompanying data ...
  • Martí Baena, Quim; Pascuet Fontanet, Andreu; Berjaga Buisan, Tomas; Caravaca Rodríguez, Miriam; Puig Costa-Jussà, Jaume; Sánchez Mejías, Avencia; Ivančić, Dimitrije; Mogas Díez, Sira; Güell Cargol, Marc, 1982-; Macía, Javier (Frontiers, 2024)
    Although blood sampling and medical imaging are well-established techniques in clinical diagnostics, they often require long post-processing procedures. Fast and simple quantification of signaling molecules can enable ...
  • Marchal, Astrid; COVID Clinicians; Bolze, Alexandre (Elsevier, 2024)
    Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an association between the HLA-B∗15:01 allele and ...
  • Cavaco, Marco; Fraga, Patrícia; Valle, Javier; Silva, Rúben D.M.; Gano, Lurdes; Correia, João D.G.; Andreu Martínez, David; Castanho, Miguel A.R.B.; Neves, Vera (BioMed Central, 2024)
    Blood-brain barrier (BBB) peptide-shuttles (BBBpS) are able to translocate the BBB and reach the brain. Despite the importance of brain targeting in pharmacology, BBBpS are poorly characterized. Currently, their development ...
  • Selma Royo, Marta; Dubois, Léonard; Manara, Serena; Armanini, Federica; Cabrera Rubio, Raúl; Vallès Colomer, Mireia; González, Sonia; Parra Llorca, Anna; Escuriet Peiró, Ramón, 1968-; Bode, Lars; Martínez Costa, Cecilia; Segata, Nicola; Collado, María Carmen (Elsevier, 2024)
    The composition and maturation of the early-life microbiota are modulated by a number of perinatal factors, whose interplay in relation to microbial vertical transmission remains inadequately elucidated. Using recent ...
  • Reynders, Tatjana; Devolder, Lindsay; Vallès Colomer, Mireia; Van Remoortel, Ann; Joossens, Marie; De Keyser, Jacques; Nagels, Guy; D'hooghe, Marie Beatrice; Raes, Jeroen (Wiley, 2020)
    Objective: Multiple sclerosis (MS) is a heterogenous, inflammatory disease of the central nervous system. Microbiota alterations in MS versus healthy controls (HC) are observed, but results are inconsistent. We studied ...

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