• UCRAID (Ukrainian Citizen and refugee electronic support in Respiratory diseases, Allergy, Immunology and Dermatology) action plan

  Bousquet, Jean; García Aymerich, Judith; Antó i Boqué, Josep Maria; Zuberbier, Torsten (Wiley, 2023)

  Eight million Ukrainians have taken refuge in the European Union. Many have asthma and/or allergic rhinitis and/or urticaria, and around 100,000 may have a severe disease. Cultural and language barriers are a major obstacle ...
• Prevalence and variability of depressive symptoms in Europe: update using representative data from the second and third waves of the European Health Interview Survey (EHIS-2 and EHIS-3)

  Arias-de la Torre, Jorge; Vilagut Saiz, Gemma, 1975-; Ronaldson, Amy; Bakolis, Ioannis; Dregan, Alex; Martín, Vicente; Martinez-Alés, Gonzalo; Molina, Antonio J.; Serrano-Blanco, Antoni; Valderas Martínez, José María; Viana, Maria Carmen; Alonso Caballero, Jordi (Elsevier, 2023)

  Background: Assessing the prevalence of clinically relevant depressive symptoms and their possible variation by country and over time could be a valuable resource to inform the development of public health policies and ...
• New insights into the role of Cutibacterium acnes-derived extracellular vesicles in inflammatory skin disorders

  Pol Cros, Maria; Mir-Pedrol, Júlia; Toloza, Lorena; Knödlseder, Nastassia; Maruotti, Julien; Zouboulis, Christos C.; Güell Cargol, Marc, 1982-; Fábrega, María José (Nature Research, 2023)

  Cutibacterium acnes (C. acnes) is one of the most prevalent bacteria that forms the human skin microbiota. Specific phylotypes of C. acnes have been associated with the development of acne vulgaris, while other phylotypes ...
• Cocaine-induced loss of LTD and social impairments are restored by fatty acid amide hydrolase inhibition

  Alegre Zurano, Laia; Cáceres-Rodriguez, Alba; Berbegal-Sáez, Paula; Lassalle, Olivier; Manzoni, Olivier; Valverde Granados, Olga (Nature Research, 2023)

  A single dose of cocaine abolishes endocannabinoid-mediated long-term depression (eCB-LTD) in the nucleus accumbens (NAc) within 24 h of administration. However, it is uncertain whether this altered neuroplasticity entails ...
• Human genetic adaptation related to cellular zinc homeostasis

  Roca-Umbert Würth, Ana; García Calleja, Jorge; Vogel González, Marina, 1993-; Fierro Villegas, José Alejandro; Ill-Raga, Gerard, 1982-; Herrera-Fernández, Víctor; Bosnjak, Anja; Muntané, Gerard; Gutiérrez García, Esteban; Campelo, Felix; Vicente García, Rubén, 1978-; Bosch Fusté, Elena (Public Library of Science (PLoS), 2023)

  SLC30A9 encodes a ubiquitously zinc transporter (ZnT9) and has been consistently suggested as a candidate for positive selection in humans. However, no direct adaptive molecular phenotype has been demonstrated. Our results ...
• Overexpression of BAPT and DBTNBT genes in Taxus baccata in vitro cultures to enhance the biotechnological production of paclitaxel

  Pérez Matas, Edgar; Hidalgo Martínez, Diego; Moyano Claramunt, Elisabet; Palazón, Javier; Bonfill Baldrich, Ma. Mercedes (Wiley, 2023)

  Paclitaxel is one of the most effective anticancer drugs ever developed. Although the most sustainable approach to its production is provided by plant cell cultures, the yield is limited by bottleneck enzymes in the taxane ...
• La presencia de las humanidades en las carreras de odontología de las universidades de Chile y de España

  Soto Araya, Milena; Baños i Díez, Josep Eladi; Moyano Claramunt, Elisabet; Pérez, Jorge (Ediciones Universidad de Salamanca, 2023)

  Se ha argumentado que la presencia de materias humanísticas permite una formación integral de los alumnos, lo que fomentaría en última instancia una mejor relación con los futuros pacientes y, por tanto, contribuiría a ...
• Some thoughts about open ccience: a few challenges and a great opportunity for science

  Pujades Corbi, Cristina (Universitat Pompeu Fabra, 2023)

  Open Science focuses on spreading knowledge generated by scientific research as soon as it is available using digital and collaborative technology. The aim is to make science more accessible, inclusive, and equitable for ...
• Topoisomeric membrane-active peptides: A review of the last two decades

  Carrera-Aubesart, Adam; Gallo, María, 1989-; Defaus, Sira; Todorovski, Toni; Andreu Martínez, David (MDPI, 2023)

  In recent decades, bioactive peptides have been gaining recognition in various biomedical areas, such as intracellular drug delivery (cell-penetrating peptides, CPPs) or anti-infective action (antimicrobial peptides, AMPs), ...
• Symptoms and impacts of familial chylomicronemia syndrome: a qualitative study of the patient experience

  Williams, Kate; Tickler, Georgina; Valdivielso, Pedro; Alonso Caballero, Jordi; Vera-Llonch, Montserrat; Cubells, Laia; Acaster, Sarah (BioMed Central, 2023)

  Background: Familial chylomicronemia syndrome (FCS) is a rare, hereditary, metabolic disorder. FCS causes high levels of triglycerides in the blood, which can lead to abdominal pain, xanthomas, and acute pancreatitis (AP). ...
• Exploring the influence of circulating endocannabinoids and nucleus accumbens functional connectivity on anorexia nervosa severity

  Miranda-Olivos, Romina; Baenas, Isabel; Steward, Trevor; Granero, Roser; Pastor, Antonio; Sánchez, Isabel; Juaneda-Seguí, Asier; Pino-Gutiérrez, Amparo del; Fernández-Formoso, José A.; Vilarrasa, Nuria; Guerrero-Pérez, Fernando; Virgili, Núria; López-Urdiales, Rafael; Jiménez Murcia, Susana; Torre Fornell, Rafael de la; Soriano Mas, Carles; Fernández Aranda, Fernando (Nature Research, 2023)

  Anorexia nervosa (AN) is a severe psychiatric disorder characterized by a harmful persistence of self-imposed starvation resulting in significant weight loss. Research suggests that alterations in the nucleus accumbens ...
• Consensus on post COVID in the Spanish national health system: Results of the CIBERPOSTCOVID eDelphi study

  Torres, Marta; Serra-Sutton, Vicky; Soriano, Joan B.; Ferrer Forés, Maria Montserrat; Trejo, Alex; Benavides, Fernando G. (Fernando García); Lumbreras, Blanca; Pérez-Gómez, Beatriz; Pijoán, José Ignacio; Monguet, Josep M.; Barbé, Ferran; Pollán, Marina; Alonso Caballero, Jordi; Espallargues, Mireia; Serrano-Blanco, Antoni (Elsevier, 2023)

  Background: In 2021, the Spanish Ministry of Health launched the CIBERPOSTCOVID project to establish what post COVID was. The present study reports the level of agreement among stakeholders on post COVID and its clinical ...
• Single-cell Bayesian deconvolution

  Torregrosa-Cortés, Gabriel; Oriola, David; Trivedi, Vikas; García Ojalvo, Jordi (Elsevier, 2023)

  Individual cells exhibit substantial heterogeneity in protein abundance and activity, which is frequently reflected in broad distributions of fluorescently labeled reporters. Since all cellular components are intrinsically ...
• A fast non-parametric test of association for multiple traits

  Garrido Martín, Diego, 1992-; Calvo, Miquel (Calvo Llorca); Reverter, Ferran; Guigó Serra, Roderic (BioMed Central, 2023)

  The increasing availability of multidimensional phenotypic data in large cohorts of genotyped individuals requires efficient methods to identify genetic effects on multiple traits. Permutational multivariate analysis of ...
• A new assemblage of late Neanderthal remains from Cova Simanya (NE Iberia)

  Morales, Juan I.; Cebrià, Artur; Soto, María; Rodríguez-Hidalgo, Antonio; Hernando, Raquel; Moreno-Ribas, Elena; Lombao, Diego; Rabuñal, José R.; Martín-Perea, David M.; García-Tabernero, Antonio; Allué, Ethel; García Basanta, Andrea; Lizano González, Esther, 1974-; Marquès i Bonet, Tomàs, 1975-; Talamo, Sahra; Tassoni, Laura; Lalueza Fox, Carles, 1965-; Fullola, Josep M.; Rosas, Antonio (Frontiers, 2023)

  This study presents an exceptional collection of 54 Late Pleistocene human remains that correspond to at least three Neanderthal individuals from Simanya Gran, the main gallery of Cova Simanya, located in the northeastern ...
• Increased paclitaxel recovery from Taxus baccata vascular stem cells using novel in situ product recovery approaches

  Santoyo-Garcia, Jorge H.; Valdivia-Cabrera, Marissa; Ochoa-Villarreal, Marisol; Casasola-Zamora, Samuel; Ripoll, Magdalena; Escrich Montañana, Ainoa; Moyano Claramunt, Elisabet; Betancor, Lorena; Halliday, Karen J.; Loake, Gary J.; Rios-Solis, Leonardo (Springer, 2023)

  In this study, several approaches were tested to optimise the production and recovery of the widely used anticancer drug Taxol® (paclitaxel) from culturable vascular stem cells (VSCs) of Taxus baccata, which is currently ...
• Classification system for nanotechnology-enabled health products with both scientific and regulatory application

  Rodríguez-Gómez, Francisco D.; Penon, Oriol; Monferrer, Dominique; Rivera Gil, Pilar, 1976- (Frontiers, 2023)

  The lack of specific regulatory guidelines for nanotechnology-enabled health products (NHPs) is hampering development and patient access to these innovative technologies. Namely, there is an urgent need for harmonized ...
• Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions

  Maury, Eduardo A.; Brain Somatic Mosaicism Network; Walsh, Christopher A. (Elsevier, 2023)

  While germline copy-number variants (CNVs) contribute to schizophrenia (SCZ) risk, the contribution of somatic CNVs (sCNVs)-present in some but not all cells-remains unknown. We identified sCNVs using blood-derived genotype ...
• A quantitative systems pharmacology model for certolizumab pegol treatment in moderate-to-severe psoriasis

  Coto-Segura, Pablo; Segú-Vergés, Cristina; Martorell, Antonio; Moreno-Ramírez, David; Jorba Argemí, Guillem; Junet, Valentin; Guerri, Filippo; Daura, Xavier; Oliva Miguel, Baldomero; Cara, Carlos; Suárez-Magdalena, Olaya; Abraham, Sonya; Mas, José Manuel (Frontiers, 2023)

  Background: Psoriasis is a chronic immune-mediated inflammatory systemic disease with skin manifestations characterized by erythematous, scaly, itchy and/or painful plaques resulting from hyperproliferation of keratinocytes. ...
• Influenza vaccination coverage rates and determinants in Greek children until the age of ten (2008-2019), the Rhea mother-child cohort

  Karachaliou, Marianna; Damianaki, Irene; Moudatsaki, Maria; Margetaki, Katerina; Roumeliotaki, Theano; Bempi, Vicky; Moudatsaki, Marina; Chatzi, Lida Vaia; Vafeiadi, Marina, 1983-; Kogevinas, Manolis (MDPI, 2023)

  Background: In Greece, influenza vaccination is currently recommended for children with high-risk conditions. There are limited data on influenza vaccination uptake among Greek children with and without high-risk conditions. ...

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