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Visualitza Articles (Departament de Medicina i Ciències de la Vida) per matèria

Visualitza Articles (Departament de Medicina i Ciències de la Vida) per matèria "Malaria"

Ara mostrant els elements 1-7 de 7

A variant in the gene FUT9 is associated with susceptibility to placental malaria infection

Sikora, Martin, 1976-; Ferrer Admetlla, Anna; Laayouni, Hafid, 1968-; Menéndez, Clara; Mayor, Alfredo; Bardaji, Azucena; Sigauque, Betuel; Mandomando, Inacio; Alonso, Pedro L.; Bertranpetit, Jaume, 1952-; Casals López, Ferran (Oxford University Press, 2009)

Malaria in pregnancy forms a substantial part of the worldwide burden of malaria, with an estimated annual death toll of up to 200,000 infants, as well as increased maternal morbidity and mortality. Studies of genetic ...
Characterization of domiphen bromide as a new fast-acting antiplasmodial agent inhibiting the apicoplastidic methyl erythritol phosphate pathway

Biosca, Arnau; Ramírez, Miriam; Gomez-Gomez, Àlex; Lafuente, Aritz; Iglesias, Valentin; Pozo Mendoza, Óscar J., 1975-; Imperial, Santiago; Fernàndez Busquets, Xavier (MDPI, 2022)

The evolution of resistance by the malaria parasite to artemisinin, the key component of the combination therapy strategies that are at the core of current antimalarial treatments, calls for the urgent identification of ...
Genetic affinities of an eradicated European Plasmodium falciparum strain

de Dios, Toni; van Dorp, Lucy; Gelabert Xirinachs, Pere, 1991-; Carøe, Christian; Sandoval Velasco, Marcela; Fregel, Rosa; Escosa, Raül; Aranda, Carles; Huijben, Silvie; Balloux, François; Gilbert, M Thomas; Lalueza Fox, Carles, 1965- (Microbiology Society, 2019)

Malaria was present in most of Europe until the second half of the 20th century, when it was eradicated through a combination of increased surveillance and mosquito control strategies, together with cross-border and political ...
Plasma MicroRNA profiling of Plasmodium falciparum biomass and association with severity of malaria disease

Gupta, Himanshu; Rubio, Mercedes; Sitoe, Antonio; Varo, Rosauro; Cisteró, Pau; Madrid, Lola; Cuamba, Inocencia; Jiménez, Alfons; Martiáñez-Vendrell, Xavier; Barrios, Diana; Pantano Rubiño, Lorena, 1982-; Brimacombe, Allison; Bustamante Pineda, Mariona; Bassat, Quique; Mayor, Alfredo (Centers for Disease Control and Prevention, 2021)

Severe malaria (SM) is a major public health problem in malaria-endemic countries. Sequestration of Plasmodium falciparum-infected erythrocytes in vital organs and the associated inflammation leads to organ dysfunction. ...
Plasmodium vivax malaria viewed through the lens of an eradicated european strain

van Dorp, Lucy; Gelabert Xirinachs, Pere, 1991-; Rieux, Adrien; de Manuel, Marc; de Dios, Toni; Gopalakrishnan, Shyam; Carøe, Christian; Sandoval Velasco, Marcela; Fregel, Rosa; Olalde Marquínez, Íñigo, 1987-; Escosa, Raül; Aranda, Carles; Huijben, Silvie; Mueller, Ivo; Marquès i Bonet, Tomàs, 1975-; Balloux, François; Gilbert, M Thomas; Lalueza Fox, Carles, 1965- (Oxford University Press, 2020)

The protozoan Plasmodium vivax is responsible for 42% of all cases of malaria outside Africa. The parasite is currently largely restricted to tropical and subtropical latitudes in Asia, Oceania, and the Americas. Though, ...
The impact of a malaria elimination initiative on school outcomes: Evidence from Southern Mozambique

Cirera, Laia; Vall-Castelló, Judit; Brew, Joe; Saúte, Francisco; Sicuri, Elisa (Elsevier, 2022)

Despite the significant improvements achieved over the last ten years, primary education attainment in Mozambique is still low. Potential reasons acting from the demand perspective include ill health, among other factors. ...
The protein aggregation inhibitor YAT2150 has potent antimalarial activity in Plasmodium falciparum in vitro cultures

Bouzón-Arnáiz, Inés; Avalos-Padilla, Yunuen; Biosca, Arnau; Caño-Prades, Omar; Román-Álamo, Lucía; Valle, Javier; Andreu Martínez, David; Moita, Diana; Prudêncio, Miguel; Arce, Elsa M.; Muñoz-Torrero, Diego; Fernàndez-Busquets, Xavier (BioMed Central, 2022)

Background: By 2016, signs of emergence of Plasmodium falciparum resistance to artemisinin and partner drugs were detected in the Greater Mekong Subregion. Recently, the independent evolution of artemisinin resistance has ...