Browsing Articles (Departament de Medicina i Ciències de la Vida) by Author "Maccarrone, Mauro"

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Epigenetic and proteomic expression changes promoted by eating addictive-like behavior

Mancino, Samantha, 1987-; Burokas, Aurelijus, 1982-; Gutiérrez Cuesta, Javier; Gutiérrez Martos, Miriam, 1989-; Martín García, Elena, 1975-; Pucci, Mariangela; Falconi, Anastasia; D'Addario, Claudio; Maccarrone, Mauro; Maldonado, Rafael, 1961- (Nature Publishing Group, 2015)

An increasing perspective conceptualizes obesity and overeating as disorders related to addictive-like processes that could share common neurobiological mechanisms. In the present study, we aimed at validating an animal ...
The endocannabinoid hydrolase FAAH is an allosteric enzyme

Dainese, Enrico; Oddi, Sergio; Simonetti, Monica; Sabatucci, Annalaura; Angelucci, Clotilde B.; Ballone, Alice; Dufrusine, Beatrice; Fezza, Filomena; De Fabritiis, Gianni; Maccarrone, Mauro (Nature Research, 2020)

Fatty acid amide hydrolase (FAAH) is a membrane-bound homodimeric enzyme that in vivo controls content and biological activity of N-arachidonoylethanolamine (AEA) and other relevant bioactive lipids termed endocannabinoids. ...

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