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Browsing Articles (Departament de Medicina i Ciències de la Vida) by Author "Abad Cortel, Etna"

Browsing Articles (Departament de Medicina i Ciències de la Vida) by Author "Abad Cortel, Etna"

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  • Moretton, Amandine; Kourtis, Savvas; Gañez-Zapater, Antoni; Calabrò, Chiara; Espinar Calvo, Maria Lorena; Fontaine, Frédéric; Darai, Evangelia; Abad Cortel, Etna; Block, Samuel; Pascual-Reguant, Laura, 1990-; Pardo-Lorente, Natalia; Ghose, Ritobrata; Vander Heiden, Matthew G.; Janic, Ana; Müller, André C.; Loizou, Joanna I.; Sdelci, Sara (EMBO Press, 2023)
    While cellular metabolism impacts the DNA damage response, a systematic understanding of the metabolic requirements that are crucial for DNA damage repair has yet to be achieved. Here, we investigate the metabolic enzymes ...
  • Best, Sarah A.; Vandenberg, Cassandra J.; Abad Cortel, Etna; Whitehead, Lachlan; Guiu, Laia; Ding, Sheryl; Brennan, Margs S.; Strasser, Andreas; Herold, Marco J.; Sutherland, Kate D.; Janic, Ana (Nature Research, 2020)
    TP53 is a critical tumor suppressor that is mutated in approximately 50% of human cancers. Unveiling the downstream target genes of TP53 that fulfill its tumor suppressor function is an area of intense investigation. Zmat3 ...
  • Abad Cortel, Etna; Sandoz, Jérémy; Romero, Gerard; Zadra, Ivan; Urgel i Solas, Júlia; Borredat, Pablo; Kourtis, Savvas; Ortet Cortada, Laura; Martínez, Carlos; Weghorn, Donate; Sdelci, Sara; Janic, Ana (BioMed Central, 2024)
    Background: TP53, the most frequently mutated gene in human cancers, orchestrates a complex transcriptional program crucial for cancer prevention. While certain TP53-dependent genes have been extensively studied, others, ...

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