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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

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  • Negrete Buela, Roger; García Gutiérrez, María Salud; Manzanares, Jorge; Maldonado, Rafael, 1961- (Elsevier, 2017)
    Joint pain is a major clinical problem mainly associated to osteoarthritis, and characterized by articular cartilage degradation resulting in a complex chronic pain state that includes nociceptive, emotional and cognitive ...
  • Valjent, Emmanuel; Corvol, Jean-Christophe; Pagès, Christiane; Besson, Marie-J.; Maldonado, Rafael, 1961-; Caboche, Jocelyne (Society for Neuroscience, 2000)
    A central feature of drugs of abuse is to induce gene expression in discrete brain structures that are critically involved in behavioral responses related to addictive processes. Although extracellular signal-regulated ...
  • Flores de los Heros, África, 1985-; Julià Hernández, Marina; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Wiley, 2016)
    BACKGROUND AND PURPOSE: Anatomical, biochemical and pharmacological evidence suggest the existence of a crosstalk between the orexinergic and endocannabinoid systems. While the orexin receptor 1 (OX1 receptor) modulates ...
  • Prindle, Arthur; Liu, Jintao; Asally, Munehiro; Ly, San; Garcia Ojalvo, Jordi; Süel, Gürol M. (Nature Research, 2015)
    The study of bacterial ion channels has provided fundamental insights into the structural basis of neuronal signalling; however, the native role of ion channels in bacteria has remained elusive. Here we show that ion ...
  • Hall, Janet; Jeggo, Penny A.; West, Catharine; Gomolka, Maria; Quintens, Roel; Badie, Christophe; Laurent, Olivier; Aerts, Ann; Anastasov, Nataša; Azimzadeh, Omid; Azizova, Tamara; Baatout, Sarah; Baselet, Bjorn; Benotmane, Mohammed A.; Blanchardon, Eric; Guéguen, Yann; Haghdoost, Siamak; Harms-Ringhdahl, Mats; Hess, Julia; Kreuzer, Michaela; Laurier, Dominique; Macaeva, Ellina; Manning, Grain; Pernot, Eileen; Ravanat, Jean-Luc; Sabatier, Laure; Tack, Karine; Tapio, Soile; Zitzelsberger, Horst; Cardis, Elisabeth (Elsevier, 2017)
    Recent epidemiology studies highlighted the detrimental health effects of exposure to low dose and low dose rate ionizing radiation (IR): nuclear industry workers studies have shown increased leukaemia and solid tumour ...
  • Fernandes, Jacqueline; Lorenzo, Ivan M.; Andrade, Yaniré N.; Garcia-Elias Heras, Anna; Serra Pascual, Selma A., 1981-; Fernández-Fernández, José Manuel, 1967-; Valverde, M. A. (Miguel Ángel), 1963- (Rockefeller University Press, 2008)
    Mechanical and osmotic sensitivity of the transient receptor potential vanilloid 4 (TRPV4) channel depends on phospholipase A(2) (PLA(2)) activation and the subsequent production of the arachidonic acid metabolites, ...
  • Middleton, Robert; Gao, Dadi; Thomas, Aubin; Singh, Babita, 1986-; Au, Amy; Wong, Justin J.-L.; Bomane, Alexandra; Cosson, Bertrand; Eyras Jiménez, Eduardo; Rasko, John E.J.; Ritchie, William (BioMed Central, 2017)
    Intron retention (IR) occurs when an intron is transcribed into pre-mRNA and remains in the final mRNA. We have developed a program and database called IRFinder to accurately detect IR from mRNA sequencing data. Analysis ...
  • Kovess, Viviane; Alonso Caballero, Jordi; Kessler, Ronald C. (Wiley-VCH Verlag, 2013)
    BACKGROUND: Although irritability is a core symptom of DSM-IV major depressive disorder (MDD) for youth but not adults, clinical studies find comparable rates of irritability between nonbipolar depressed adults and youth. ...
  • Martín-Ontiyuelo, Clara; Rodó-Pin, Anna; Sancho Muñoz, Antonio; Martinez-Llorens, Juana María; Admetlló Papiol, Mireia; Molina Ferragut, Luis; Gea Guiral, Joaquim; Barreiro Portela, Esther; Rodríguez Chiaradía, Diego A. (DOVE Medical Press, 2019)
    There is evidence that iron plays a key role in the adequate functioning of skeletal muscle. While it has been demonstrated that nonanemic iron deficiency (NAID) affects exercise tolerance and response to exercise training ...
  • García Santamarina, Sarela, 1978-; Boronat i Llop, Susanna, 1965-; Calvo, Isabel A.; Rodríguez Gabriel, Miguel; Ayté del Olmo, José; Molina, Henrik; Hidalgo Hernando, Elena (Mary Ann Liebert, Inc, 2013)
    Cysteine oxidation mediates oxidative stress toxicity and signaling. It has been long proposed that the thioredoxin (Trx) system, which consists of Trx and thioredoxin reductase (Trr), is not only involved in recycling ...
  • Fröhlich, Matthias; Pinart, Mariona; Keller, Theresa; Reich, Andreas; Cabieses, Báltica; Hohmann, Cynthia; Postma, Dirkje S.; Bousquet, Jean; Antó i Boqué, Josep Maria; Keil, Thomas; Roll, Stephanie (BioMed Central, 2017)
    BACKGROUND: Allergic rhinitis and asthma as single entities affect more boys than girls in childhood but more females in adulthood. However, it is unclear if this prevalence sex-shift also occurs in allergic rhinitis and ...
  • Dobón Berenguer, Begoña, 1987-; Rossell, Carla; Walsh Capdevila, Sandra; Bertranpetit, Jaume, 1952- (BioMed Central, 2019)
    Background: During the modern human expansion, new environmental pressures may have driven adaptation, especially in genes related to the perception of ingested substances and their detoxification. Consequently, positive ...
  • Soriano Tarraga, Carolina; Giralt-Steinhauer, Eva; Mola Caminal, Marina; Vivanco Hidalgo, Rosa María; Ois Santiago, Angel Javier; Rodríguez‐Campello, Ana; Cuadrado Godia, Elisa; Sayols, Sergi; Elosua Llanos, Roberto; Roquer, Jaume; Jiménez‐Conde, Jordi ( Impact Journals, 2016)
    Ischemic stroke is associated with aging. It is possible to predict chronological age by measuring age-related changes in DNA methylation from multiple CpG sites across the genome, known as biological age. The difference ...
  • Lyle, Robert; Prandini, Paola; Osoegawa, Kazutoyo; Ten Hallers, Boudewijn; Humphray, Sean; Zhu, Baoli; Eyras Jiménez, Eduardo; Castelo Valdueza, Robert; Bird, Christine P.; Gagos, Sarantos; Scott, Carol; Cox, Antony; Deutsch, Samuel; Ucla, Catherine; Cruts, Marc; Dahoun, Sophie; She, Xinwei; Bena, Frederique; Wang, Sheng-Yue; Broeckhoven, Christine van; Eichler, Evan E.; Guigó Serra, Roderic; Rogers, Jane; De Jong, Pieter J.; Reymond, Alexandre; Antonarakis, Stylianos E. (Cold Spring Harbor Laboratory Press-CSHL Press, 2007)
    The goals of the human genome project did not include sequencing of the heterochromatic regions. We describe here an initial sequence of 1.1 Mb of the short arm of human chromosome 21 (HSA21p), estimated to be 10% of 21p. ...
  • Chiva, Cristina; Pastor, Olga; Trilla Fuertes, Lucía; Gámez Pozo, Angelo; Fresno Vara, Juan Ángel; Sabidó Aguadé, Eduard, 1981- (American Chemical Society (ACS), 2019)
    Targeted proteomics has become the method of choice for biomarker validation in human biopsies due to its high sensitivity, reproducibility, accuracy, and precision. However, for targeted proteomics to be transferred to ...
  • Neves, Joana; Parada, Carolina; Chamizo, Mireia; Giráldez, Fernando (Company of Biologists, 2011)
    Hair cells of the inner ear sensory organs originate from progenitor cells located at specific domains of the otic vesicle: the prosensory patches. Notch signalling is necessary for sensory development and loss of function ...
  • Mocavini, Ivano; Pippa, Simone; Licursi, Valerio; Paci, Paola; Trisciuoglio, Daniela; Mannironi, Cecilia; Presutti, Carlo; Negri, Rodolfo (Wiley Open Access, 2019)
    JARID1B/KDM5B histone demethylase's mRNA is markedly overexpressed in breast cancer tissues and cell lines and the protein has been shown to have a prominent role in cancer cell proliferation and DNA repair. However, the ...
  • Hénaff, Elizabeth; Zapata Ortiz, Luis, 1985-; Casacuberta, Josep M.; Ossowski, Stephan (BioMed Central, 2015)
    Background: Transposable elements are major players in genome evolution. Transposon insertion polymorphisms can/ntranslate into phenotypic differences in plants and animals and are linked to different diseases including ...
  • Bosque Prous, Marina, 1984-; Espelt Hernández, Albert, 1981-; Sordo, Luis; Guitart, Anna (Guitart i Garcia); Brugal i Puig, M. Teresa; Bravo, María José (Public Library of Science (PLoS), 2015)
    BACKGROUND: To estimate the incidence of hazardous drinking in middle-aged people during an economic recession and ascertain whether individual job loss and contextual changes in unemployment influence the incidence rate ...
  • Rodríguez-Loureiro, Lucía; Artazcoz Lazcano, Lucía, 1963-; López Ruiz, María, 1982-; Assunção, Ada Ávila; Benavides, Fernando G. (Fernando García) (Escola Nacional De Saúde Pública, Fundação Oswaldo Cruz, 2019)
    The objectives were to assess the joint effect of working hours paid per week and multiple job holding on sickness absence, by sex, among basic education teachers in Brazil. This study is based on a survey carried out over ...

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