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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

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  • Wang, Jiang; Olsson, Simon; Wehmeyer, Christoph; Pérez, Adrià; Charron, Nicholas E.; De Fabritiis, Gianni; Noé, Frank; Clementi, Cecilia (American Chemical Society (ACS), 2019)
    Atomistic or ab initio molecular dynamics simulations are widely used to predict thermodynamics and kinetics and relate them to molecular structure. A common approach to go beyond the time- and length-scales accessible ...
  • Kharraz, Yacine; Guerra, Joan; Mann, Christopher J.; Serrano, Antonio L.; Muñoz Cánoves, Pura, 1962- (Hindawi, 2013)
    Effective repair of damaged tissues and organs requires the coordinated action of several cell types, including infiltrating inflammatory cells and resident cells. Recent findings have uncovered a central role for macrophages ...
  • Buxadé Fortuny, Maria; Huerga Encabo, Hector, 1989-; Riera-Borrull, Marta; Quintana-Gallardo, Lucía; López-Cotarelo, Pilar; Tellechea Recarte, Mónica, 1989-; Martínez-Martínez, Sara; Redondo, Juan Miguel; Martín Caballero, Juan; Flores, Juana M.; Bosch, Elena; Rodríguez-Fernández, José Luis; Aramburu, José (Aramburu Beltrán); López Rodríguez, M. Cristina (Rockefeller University Press, 2018)
    MHCII in antigen-presenting cells (APCs) is a key regulator of adaptive immune responses. Expression of MHCII genes is controlled by the transcription coactivator CIITA, itself regulated through cell type-specific promoters. ...
  • Bousquet, Jean; MASK study group; Antó i Boqué, Josep Maria; Sunyer Deu, Jordi (Elsevier, 2016)
    The selection of pharmacotherapy for patients with allergic rhinitis (AR) depends on several factors, including age, prominent symptoms, symptom severity, control of AR, patient preferences, and cost. Allergen exposure and ...
  • Lee, Dong-yeon D.; Galera Laporta, Letícia, 1985-; Bialecka-Fornal, Maja; Moon, Eun Chae; Shen, Zhouxin; Briggs, Steven P.; García Ojalvo, Jordi; Süel, Gürol M. (Elsevier, 2019)
    Bacteria exhibit cell-to-cell variability in their resilience to stress, for example, following antibiotic exposure. Higher resilience is typically ascribed to "dormant" non-growing cellular states. Here, by measuring ...
  • Muñoz, Manuel Javier; Nieto Moreno, Nicolás; Giono, Luciana E.; Cambindo Botto, Adrián E.; Dujardin, Gwendal; Bastianello, Giulia; Lavore, Stefania; Torres Méndez, Antonio; Menck, Carlos Frederico Martins; Blencowe, Benjamin J.; Irimia, Manuel; Foiani, Marco; Kornblihtt, Alberto R. (Elsevier, 2017)
    We have previously found that UV irradiation promotes RNA polymerase II (RNAPII) hyperphosphorylation and subsequent changes in alternative splicing (AS). We show now that UV-induced DNA damage is not only necessary but ...
  • Sánchez-Rodríguez, María Dolores; Marco Navarro, Ester; Annweiler, Cédric; Ronquillo-Moreno, Natalia; Tortosa Rodríguez, Andrea; Vázquez Ibar, Olga; Escalada, Ferran; Duran Jordà, Xavier, 1974-; Muniesa Portoles, Josep M. (Elsevier, 2017)
    OBJECTIVE: To determine the relationships between malnutrition and nutrition-related conditions according to the European Society of Clinical Nutrition and Metabolism (ESPEN) consensus and guidelines and clinical outcomes ...
  • López Arribillaga, Erika; Rodilla, Verónica; Colomer Montañá, Carlota; Vert, Anna; Shelton, Amy; Cheng, Jason H.; Yan, Bing; González Pérez, Abel; Junttila, Melissa R.; Iglesias Coma, Mar; Torres, Ferran; Albanell Mestres, Joan; Villanueva, Alberto; Bigas Salvans, Anna; Siebel, Christian W.; Espinosa Blay, Lluís (Nature Research, 2018)
    Delta ligands regulate Notch signaling in normal intestinal stem cells, while Jagged1 activates Notch in intestinal adenomas carrying active β-catenin. We used the ApcMin/+ mouse model, tumor spheroid cultures, and ...
  • Pérez-Ortuño, Raúl; Fu, Marcela; Martínez-Sánchez, Jose M.; Martínez, Cristina; Ballbé, Montse; Pérez-Ortuño, Raúl; Saltó i Cerezuela, Esteve; Pascual Esteban, José A.; Fernández, Esteve (Elsevier, 2017)
    AIMS: The objectives of the present study were to describe smoking prevalence and compare the smoking attributes of adult smokers according to the type of tobacco product consumed. METHODS: Repeated cross-sectional surveys ...
  • Vandendriessche, Benjamin; Goethals, An; Simats, Alba; Hamme, Evelien Van; Brouckaert, Peter; Cauwels, Anje (BioMed Central, 2014)
    Background: MAPK-activated protein kinase 2 (MK2) plays a pivotal role in the cell response to (inflammatory) stress. Among others, MK2 is known to be involved in the regulation of cytokine mRNA metabolism and regulation ...
  • Millán Ariño, Lluís, 1984-; Islam, Abul, 1978-; Izquierdo Bouldstridge, Andrea; Mayor, Regina; Terme, Jean Michel; Luque, Neus; Sancho Medina, Mónica; López Bigas, Núria; Jordan, Albert (Oxford University Press, 2014)
    Seven linker histone H1 variants are present in human somatic cells with distinct prevalence across cell types. Despite being key structural components of chromatin, it is not known whether the different variants have ...
  • Aguilar, Daniel; Oliva Miguel, Baldomero; Marino Buslje, Cristina (Public Library of Science (PLoS), 2012)
    Amino acids committed to a particular function correlate tightly along evolution and tend to form clusters in the 3D structure of the protein. Consequently, a protein can be seen as a network of co-evolving clusters of ...
  • Larenas-Linnemann, Desirée; Antó i Boqué, Josep Maria; Bousquet, Jean (UNLISTED PUBLISHER, 2019)
    Aunque existen guías clínicas de alta calidad sobre rinitis alérgica, numerosos pacientes reciben tratamiento deficiente, en parte debido al alto grado de automedicación. MASK (Mobile Airways Sentinel Network) forma parte ...
  • Bousquet, Jean; Antó i Boqué, Josep Maria; MASK study group (BioMed Central, 2018)
    mHealth, such as apps running on consumer smart devices is becoming increasingly popular and has the potential to profoundly affect healthcare and health outcomes. However, it may be disruptive and results achieved are not ...
  • Álvarez Larrán, Alberto; Angona Figueras, Anna; Ancochea Serra, Agueda; García-Pallarols, Francesc; Fernández Rodríguez, M. Concepción; Longarón Rozalen, Raquel; Bellosillo Paricio, Beatriz; Besses Raebel, Carles (Wiley, 2016)
    Masked polycythaemia vera (PV) has been proposed as a new entity with poorer outcome than overt PV. In this study, the initial clinical and laboratory characteristics, response to treatment and outcome of masked and overt ...
  • Güerri Fernández, Roberto; Gayete, Angel; Balcells Vilarnau, Eva, 1967-; Ramírez Sarmiento, Alba; Vollmer, Ivan; García Aymerich, Judith; Gea Guiral, Joaquim; Orozco Levi, Mauricio (Elsevier, 2010)
    BACKGROUND: The potential role of decreased respiratory muscle mass, if any, in mediating the susceptibility to exacerbation in COPD patients has not been determined. We hypothesized that a decrease in respiratory muscle ...
  • Cantacorps, Lídia; Alfonso-Loeches, Silvia; Moscoso Castro, Maria, 1988-; Cuitavi, Javier; Gracia Rubio, Irene, 1986-; López Arnau, Raúl; Escubedo, Elena; Guerri, Consuelo; Valverde Granados, Olga (Elsevier, 2017)
    Alcohol binge drinking is on the increase in the young adult population, and consumption during pregnancy can be deleterious for foetal development. Maternal alcohol consumption leads to a wide range of long-lasting ...
  • Voerman, Ellis; Vrijheid, Martine; Jaddoe, Vincent W. V. (Public Library of Science (PLoS), 2019)
    Background: Maternal obesity and excessive gestational weight gain may have persistent effects on offspring fat development. However, it remains unclear whether these effects differ by severity of obesity, and whether these ...
  • Birks, Laura; Guxens Junyent, Mònica; Papadopoulou, Eleni, 1985-; Alexander, Jan; Ballester Díez, Ferran; Estarlich, Marisa; Gallastegui, Mara; Ha, Mina; Haugen, Margaretha; Huss, Anke; Kheifets, Leeka; Lim, Hyungryul; Olsen, Jørn; Santa Marina, Loreto; Sudan, Madhuri; Vermeulen, Roel; Vrijkotte, Tanja; Cardis, Elisabeth; Vrijheid, Martine (Elsevier, 2017)
    INTRODUCTION: Previous studies have reported associations between prenatal cell phone use and child behavioral problems, but findings have been inconsistent and based on retrospective assessment of cell phone use. This ...
  • Wotton, Karl R.; Jiménez Guri, Eva; Jaeger, Johannes, 1973- (Public Library of Science (PLoS), 2015)
    Axis specification and segment determination in dipteran insects are an excellent model system for comparative analyses of gene network evolution. Antero-posterior polarity of the embryo is established through systems of ...

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