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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

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  • Millán-Uclés, África; Zuluaga, Susana; Marqués, Marta; Vallejo-Díaz, Jesus; Sanz, Lorena; Cariaga-Martínez, Ariel E.; Real, Francisco X.; Carrera, Ana C. (Impact Journals, 2016)
    Alterations in phosphatidylinositol 3-kinase (PI3K) and in PTEN (phosphatase and tensin homolog), the negative regulator of the PI3K pathway, are found in nearly half of human tumors. As PI3Kβ, the main isoform activated ...
  • Skouras, Stavros; Torner, Jordi; Andersson, Patrik; Koush, Yury; Falcon, Carles; Minguillón, Carolina; Fauria, Karine; Alpiste, Francesc; Blenow, Kaj; Zetterberg, Henrik; Gispert López, Juan Domingo; Molinuevo, José Luis; ALFA Study (Oxford University Press, 2020)
    Research into hippocampal self-regulation abilities may help determine the clinical significance of hippocampal hyperactivity throughout the pathophysiological continuum of Alzheimer's disease. In this study, we aimed to ...
  • Berthoux, Coralie; Hamieh, Al Mahdy; Rogliardo, Angelina; Doucet, Emilie L.; Coudert, Camille; Ango, Fabrice; Grychowska, Katarzyna; Chaumont-Dubel, Séverine; Zajdel, Pawel; Maldonado, Rafael, 1961-; Bockaert, Joël; Marin, Philippe; Bécamel, Carine (EMBO Press, 2020)
    Cannabis abuse during adolescence confers an increased risk for developing later in life cognitive deficits reminiscent of those observed in schizophrenia, suggesting common pathological mechanisms that remain poorly ...
  • Casas, Lidia; Tischer, Christina; Wouters, Inge M.; Torrent Quetglas, Maties; Gehring, Ulrike; García Esteban, Raquel; Thiering, Elisabeth; Postma, Dirkje S.; de Jongste, Johan; Smit, Henriëtte A.; Borrás Santos, Alícia, 1974-; Zock, Jan-Paul; Hyvärinen, Anne; Heinrich, Joachim; Sunyer Deu, Jordi (BioMed Central, 2013)
    BACKGROUND: Inflammation is a key factor in the pathogenesis of respiratory diseases. Early life exposure to microbial agents may have an effect on the development of the immune system and on respiratory health later in ...
  • Cuadrado Godia, Elisa (Medknow Publications, 2015)
  • Pérez-Saez, María José; Pascual Santos, Julio; Portolés, José; GEODAS Group (BioMed Central, 2019)
    BACKGROUND: Spain has dramatically increased the number of controlled circulatory death donors (cDCD). The initial selection criteria for considering cDCD for kidney transplantation (KT) have been expanded progressively, ...
  • Fa-Binefa, Manel; Clarà Velasco, Alberto; Pérez-Fernández, Silvia; Grau Magaña, Maria; Dégano, Irene R.; Martí-Lluch, Ruth; Ramos, Rafel; Marrugat de la Iglesia, Jaume; Elosua Llanos, Roberto (Elsevier, 2019)
    Early smoking onset age (SOA) is a public health concern with scant empirical evidence of its role in health outcomes. The study had two aims: i) to assess whether an early SOA was associated with the risk of fatal and ...
  • Agier, Lydiane; Basagaña Flores, Xavier; Maitre, Léa; Casas Sanahuja, Maribel; de Castro, Montserrat; Donaire González, David; Nieuwenhuijsen, Mark J.; Robinson, Oliver; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; Valentín, Antònia; Vrijheid, Martine; Siroux, Valérie (Elsevier, 2019)
    Background: Several single-exposure studies have documented possible effects of environmental factors on lung function, but none has relied on an exposome approach. We aimed to evaluate the association between a broad range ...
  • Aguilera Jiménez, Inmaculada, 1977-; Pedersen, Marie; García Esteban, Raquel; Ballester Díez, Ferran; Basterrechea, Mikel; Esplugues, Ana; Fernández Somoano, Ana; Lertxundi, Aitana; Tardón, Adonina; Sunyer Deu, Jordi (National Institute of Environmental Health Sciences (NIEHS), 2013)
    Background: Prenatal and early-life periods may be critical windows for harmful effects of air pollution on infant health. Objectives: We studied the association of air pollution exposure during pregnancy and the first ...
  • Kawakami, Norito; Alonso Caballero, Jordi; Kessler, Ronald C. (Elsevier, 2012)
    Background: Better information on the human capital costs of early-onset mental disorders could increase sensitivity of policy makers to the value of expanding initiatives for early detection and treatment. Data are presented ...
  • Papp, Csaba; Kocsis, Katica; Tóth, Renáta; Bodai, László; Willis, Jesse R.; Ksiezopolska, Ewa; Lozoya-Pérez, Nancy E.; Vágvölgyi, Csaba; Mora Montes, Hector; Gabaldón Estevan, Juan Antonio, 1973-; Nosanchuk, Joshua D.; Gácser, Attila (American Society for Microbiology, 2018)
    Candida species are a major cause of life-threatening bloodstream infections worldwide. Although Candida albicans is responsible for the vast majority of infections, the clinical relevance of other Candida species has also ...
  • Haro Moreno, Jose M.; Rodríguez Valera, Francisco; Rosselli, Riccardo; Martínez Hernández, Francisco; Roda García, Juan J.; Lluesma Gómez, Mónica; Fornas Carreño, Oscar; Martínez García, Manuel; López Pérez, Mario (Wiley, 2020)
    Members of the SAR11 clade, despite their high abundance, are often poorly represented by metagenome-assembled genomes. This fact has hampered our knowledge about their ecology and genetic diversity. Here we examined 175 ...
  • Colell Ortega, Esther, 1961-; Sánchez Niubò, Albert; Delclòs i Clanchet, Jordi, 1956-; Benavides, Fernando G. (Fernando García); Domingo i Salvany, Antònia (Wiley, 2015)
    AIMS: To examine changes in the use of alcohol, cannabis and hypnotics/sedatives between two periods (before and during Spain's economic crisis), and to identify differences in the change between employed and unemployed ...
  • Morales Suárez-Varela, María; Llopis-González, Agustín; González Candela, Fernando; Astray, Jenaro; Alonso Caballero, Jordi; Garin Boronat, Olatz, 1979-; Castro, Ady; Galán, Juan Carlos; Soldevila, Núria; Castilla, Jesús; Godoy i García, Pere; Delgado Rodríguez, Miguel; Martin, Vincent S.; Mayoral, José María; Pumarola, Tomás; Quintana, José María; Tamames, Sonia; Rubio-López, Nuria; Dominguez, Angela (Tehran University of Medical Sciences, 2016)
    Background: The healthcare and socio-economic burden resulting from influenza A (H1N1) pdm09 in Spain was considerable. Our aim was to estimate and compare the management (resource utilization) and economic healthcare ...
  • Becerra Bachino, Virginia, 1975-; Ávila Pacheco, Mónica Marcela, 1984-; Jiménez Conde, Jordi; Cortes-Sanabria, Laura; Pardo Cladellas, Yolanda; Garin Boronat, Olatz, 1979-; Pont Acuña, Àngels; Alonso Caballero, Jordi; Cots Reguant, Francesc; Ferrer Forés, Maria Montserrat; Multicentric Spanish Group of Clinically Localized Prostate Cancer (BioMed Central, 2016)
    Background: Our objective was to assess the efficiency of treatments in patients with localized prostate cancer, by synthesizing available evidence from European economic evaluations through systematic review. Methods: ...
  • Muñoz Cánoves, Pura, 1962-; Carvajal, Jaime J.; López de Munain, Adolfo; Izeta, Ander (Frontiers, 2016)
  • Bosio, Mattia; Drechsel, Oliver; Rahman, Rubayte; Muyas, Francesc; Rabionet, Raquel; Bezdan, Daniela; Domènech Salgado, Laura, 1989-; Hor, Hyun; Schott, Jean-Jacques; Munell, Francina; Colobran, Roger; Macaya, Alfons; Estivill, Xavier, 1955-; Ossowski, Stephan (Wiley, 2019)
    Mendelian diseases have shown to be an and efficient model for connecting genotypes to phenotypes and for elucidating the function of genes. Whole-exome sequencing (WES) accelerated the study of rare Mendelian diseases in ...
  • Pires Hartwig, Fernando; Dalmau Bueno, Albert; Guxens Junyent, Mònica; Bustamante Pineda, Mariona; Gomes Victora, Cesar (Oxford University Press, 2019)
    Background: Accumulating evidence suggests that breastfeeding benefits children’s intelligence, possibly due to long-chain polyunsaturated fatty acids (LC-PUFAs) present in breast milk. Under a nutritional adequacy hypothesis, ...
  • Mortamais, Marion; Pujol Martí, Jesús, 1981-; van Drooge, Barend L.; Macià, Dídac; Martínez-Vilavella, Gerard; Reynes, Christelle; Sabatier, Robert; Rivas, Ioar; Grimalt Obrador, Joan; Forns i Guzman, Joan, 1981-; Álvarez Pedrerol, Mar; Querol, Xavier; Sunyer Deu, Jordi (Elsevier, 2017)
    Background: Polycyclic aromatic hydrocarbons (PAHs) have been proposed as environmental risk factors for attention deficit hyperactivity disorder (ADHD). The effects of these pollutants on brain structures potentially ...
  • Riera Oliva, Marta; Márquez, Eva; Clotet, Sergi; Gimeno, Javier; Roca-Ho, Heleia; Lloreta Trull, Josep, 1958-; Juanpere, Nuria; Batlle, Daniel; Pascual Santos, Julio; Soler, María José (Public Library of Science (PLoS), 2014)
    We studied the non-obese diabetic (NOD) mice model because it develops autoimmune diabetes that resembles human type 1 diabetes. In diabetic mice, urinary albumin excretion (UAE) was ten-fold increased at an “early stage” ...

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