Benvinguts al Repositori Digital de la UPF

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

Ordena per: Ordre: Resultats:

  • Fattorini, Simone; Borger, Paulo A.V.; Dapporto, Leonardo; Strona, Giovanni (Wiley, 2017)
  • Borràs, Eva; Sabido Aguade, Eduard (Wiley, 2017)
    Targeted proteomics has gained significant popularity in mass spectrometry-based protein quantification as a method to detect proteins of interest with high sensitivity, quantitative accuracy and reproducibility. However, ...
  • De Toma, Ilario; Manubens Gil, Linus; Ossowski, Stephan; Dierssen, Mara (Hindawi, 2016)
    One of the most challenging questions in neuroscience is to dissect how learning and memory, the foundational pillars of cognition, are grounded in stable, yet plastic, gene expression states. All known epigenetic mechanisms ...
  • Castro Sánchez, Sheila; Álvarez Satta, María; Tohamy, Mohamed A.; Beltran, Sergi; Derdak, Sophia; Valverde, Diana (Public Library of Science (PLoS), 2017)
    Ciliopathies are a group of rare disorders characterized by a high genetic and phenotypic variability, which complicates their molecular diagnosis. Hence the need to use the latest powerful approaches to faster identify ...
  • Ferreiro Neira, Isabel; Joaquin i Caudet, Manel; Islam, Abul, 1978-; Gómez López, Gonzalo; Barragan, Montserrat; Lombardía, Luís; Domínguez, Orlando; Pisano, David G.; López Bigas, Núria; Nebreda, Ángel R.; Posas Garriga, Francesc (BioMed Central, 2010)
    Background: Cells have the ability to respond and adapt to environmental changes through activation of stress-activated protein kinases (SAPKs). Although p38 SAPK signalling is known to participate in the regulation of ...
  • Telford, Marco, 1984-; Navarro i Cuartiellas, Arcadi, 1969-; Santpere Baró, Gabriel, 1981- (Nature Publishing Group, 2018)
    Human herpesviruses 6-A and -B (HHV-6A, HHV-6B) are ubiquitous in human populations worldwide. These viruses have been associated with several diseases such as multiple sclerosis, Hodgkin's lymphoma or encephalitis. Despite ...
  • Figueras, Antonio; Corvelo, André; Gómez Garrido, Jèssica; Gut, Marta; Gut, Ivo Glynne; Marcet Houben, Marina; Vlasova, Anna; Hermoso Pulido, Antonio; Guigó Serra, Roderic; Gabaldón Estevan, Juan Antonio, 1973-; Alioto, Tyler; Martínez, Paulino (Oxford University Press, 2016)
    The turbot is a flatfish (Pleuronectiformes) with increasing commercial value, which has prompted active genomic research aimed at more efficient selection. Here we present the sequence and annotation of the turbot genome, ...
  • Solé Morata, Neus, 1988-; García-Fernández, Carla; Urasin, Vadim; Bekada, Asmahan; Fadhlaoui-Zid, Karima; Zalloua, Pierre A; Comas, David, 1969-; Calafell i Majó, Francesc (Nature Publishing Group, 2017)
    E-M183 (E-M81) is the most frequent paternal lineage in North Africa and thus it must be considered to explore past historical and demographical processes. Here, by using whole Y chromosome sequences from 32 North African ...
  • Ferré Fernández, Jesús José; Aroca Aguilar, José Daniel; Medina Trillo, Cristina; Bonet Fernández, Juan Manuel; Méndez Hernández, Carmen Dora; Morales Fernández, Laura; Cortón, Marta; Cabañero Valera, María José; Gut, Marta; Tonda, Raúl; Ayuso, Carmen; Coca Prados, Miguel; García Feijóo, Julián; Escribano, Julio (Nature Publishing Group, 2017)
    Congenital glaucoma (CG) is a heterogeneous, inherited and severe optical neuropathy that originates from maldevelopment of the anterior segment of the eye. To identify new disease genes, we performed whole-exome sequencing ...
  • Zheng, Hou-Feng; Calderari, Sophie; Grinberg, Daniel; Gauguier, Dominique; Richards, J. Brent (Nature Publishing Group, 2015)
    The extent to which low-frequency (minor allele frequency (MAF) between 1-5%) and rare (MAF ≤ 1%) variants contribute to complex traits and disease in the general population is mainly unknown. Bone mineral density (BMD) ...
  • Ciryam, Prajwal; Tartaglia, Gian Gaetano; Morimoto, Richard I.; Dobson, Christopher M.; Vendruscolo, Michele (Elsevier, 2013)
    The maintenance of protein solubility is a fundamental aspect of cellular homeostasis because protein aggregation is associated with a wide variety of human diseases. Numerous proteins unrelated in sequence and structure, ...
  • Sampson, Valerie B.; David, Justin M.; Puig Borreil, Isabel; Patil, Pratima U.; García de Herreros, Antonio; Thomas, George V.; Rajasekaran, Ayyappan K. (Public Library of Science (PLoS), 2014)
    The Wilms' tumor transcription factor (WT1) was originally classified as a tumor suppressor, but it is now known to also be associated with cancer progression and poor prognosis in several malignancies. WT1 plays an essential ...
  • Valle Pérez, Beatriz del; Casagolda, David; Lugilde, Ero; Valls, Gabriela; Codina, Montserrat; Dave, Natàlia; García de Herreros, Antonio; Duñach, Mireia (Company of Biologists, 2011)
    p120-catenin is an E-cadherin-associated protein that modulates E-cadherin function and stability. In response to Wnt3a, p120-catenin is phosphorylated at Ser268 and Ser269, disrupting its interaction with E-cadherin. Here, ...
  • de Jaime Soguero, Anchel; Aulicino, Francesco, 1987-; Ertaylan, Gokhan; Griego, Anna; Cerrato, Aniello; Tallam, Aravind; del Sol, Antonio; Cosma, Maria Pia, 1970-; Lluis Viñas, Frederic (Public Library of Science (PLoS), 2017)
    Understanding the mechanisms regulating cell cycle, proliferation and potency of pluripotent stem cells guarantees their safe use in the clinic. Embryonic stem cells (ESCs) present a fast cell cycle with a short G1 phase. ...
  • Parodi, Jorge; Montecinos Oliva, Carla; Varas, Rodrigo; Alfaro, Iván E.; Serrano, Felipe G.; Varas Godoy, Manuel; Muñoz López, Francisco José, 1964-; Cerpa, Waldo; Godoy Zeballos, Juan Alejandro, 1959-; Inestrosa, Nibaldo C. (Elsevier, 2015)
    Hippocampal synapses play a key role in memory and learning processes by inducing long-term potentiation and depression. Wnt signaling is essential in the development and maintenance of synapses via several mechanisms. We ...
  • Pujadas, Gemma; Cervantes, Sara; Tutusaus, Anna; Ejarque, Miriam; Sánchez, Lidia; García, Ainhoa; Esteban, Yaiza; Fargas, Laura; Alsina i Español, Berta; Hartmann, Christian; Gomis, Ramon; Gasa, Rosa (Nature Publishing Group, 2016)
    Transcriptional and signaling networks establish complex cross-regulatory interactions that drive cellular differentiation during development. Using microarrays we identified the gene encoding the ligand Wnt9a as a candidate ...
  • Campos Sańchez, Elena; Deleyto Seldas, Nerea; Domínguez, Verónica; Carrillo, Enrique; Ura, Kiyoe; Rocha, Pedro P.; Kim, Jung Hyun; Aljoufi, Arafat; Esteve-Codina, Anna; Dabad, Marc; Gut, Marta; Heyn, Holger; Kaneda, Yasufumi; Nimura, Keisuke; Skok, Jane Amanda; Martínez Frías, María Luísa; Cobaleda, César (Elsevier, 2017)
    Immunodeficiency is one of the most important causes of mortality associated with Wolf-Hirschhorn syndrome (WHS), a severe rare disease originated by a deletion in chromosome 4p. The WHS candidate 1 (WHSC1) gene has been ...
  • Merino-Salazar; Pamela; Artazcoz Lazcano, Lucía, 1963-; Cornelio, Cecilia; Iñiguez, María José Itatí; Rojas, Marianela; Martínez-Iñigo, David; Vives, Alejandra; Funcasta, Lorena; Benavides, Fernando G. (Fernando García) (BMJ Publishing Group, 2017)
    OBJECTIVE: To describe working and employment conditions, and health status between non-agricultural employees with a written contract from Colombia, Argentina, Chile, Central America and Uruguay. METHODS: We compared data ...
  • Colell Ortega, Esther, 1961-; Sánchez Niubò, Albert; Benavides, Fernando G. (Fernando García); Delclòs i Clanchet, Jordi, 1956-; Domingo i Salvany, Antònia (Wiley-Blackwell, 2014)
    BACKGROUND: Workers may drink to cope with stress or to overcome negative emotions arising from an aversive working context, but results of previous studies are inconclusive on the specific work features affecting alcohol ...
  • Fan, Zhenxin; Silva, Pedro; Gronau, Ilan; Wang, Shuoguo; Serres Armero, Aitor; Schweizer, Rena M.; Ramírez, Oscar; Pollinger, John; Galaverni, Marco; Ortega Del-Vecchyo, Diego; Du, Lianming; Zhang, Wenping; Zhang, Zhihe; Xing, Jinchuan; Vilà, Carles; Marquès i Bonet, Tomàs, 1975-; Godinho, Raquel; Yue, Bisong; Wayne, Robert K. (Cold Spring Harbor Laboratory Press (CSHL Press), 2016)
    The gray wolf (Canis lupus) is a widely distributed top predator and ancestor of the domestic dog. To address questions about wolf relationships to each other and dogs, we assembled and analyzed a data set of 34 canine ...