Benvinguts al Repositori Digital de la UPF

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

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  • Boronat i Llop, Susanna, 1965-; Domènech, Alba; Carmona, Mercè; García Santamarina, Sarela, 1978-; Bañó, M. Carmen; Ayté del Olmo, José; Hidalgo Hernando, Elena (Public Library of Science (PLoS), 2017)
    The thioredoxin and glutaredoxin pathways are responsible of recycling several enzymes which undergo intramolecular disulfide bond formation as part of their catalytic cycles such as the peroxide scavengers peroxiredoxins ...
  • Aso Pérez, Ester; Renoir, Thibault; Valverde Granados, Olga; Lanfumey, Laurence; Maldonado, Rafael, 1961-; Hamon, Michel; Ledent, Catherine; Mengod, Guadalupe (Wiley-Blackwell, 2009)
    Serotonergic and endocannabinoid systems are important substrates for the control of emotional behavior and growing evidence show an involvement in the pathophysiology of mood disorders. In the present study, the absence ...
  • Rizzo, Valeria; Sánchez Fernández, David; Fresneda, Javier; Cieslak, Alexandra; Ribera, Ignacio (BioMed Central, 2015)
    Background: A key question in evolutionary biology is the relationship between species traits and their habitats. Caves offer an ideal model to test the adjustment of species to their surrounding temperature, as they provide ...
  • González, Josefa; Martínez, José; Makalowski, Wojciech (BioMed Central, 2015)
    Background. Transposable elements (TEs) play an important role in genome function and evolution. It has been shown that TEs are a considerable source of adaptive changes in the genome of Drosophila melanogaster. Specifically, ...
  • Pascual-Reguant, Laura; Blanco, Enrique; Galan, Silvia; Le Dily, François; Cuartero, Yasmina; Serra-Bardenys, Gemma; Di Carlio, Valerio; Iturbide Martínez de Albéniz, Ane, 1989-; Cebrià i Costa, Joan Pau, 1989-; Nonell Mazelón, Lara; García de Herreros, Antonio; Di Croce, Luciano; Marti-Renom, Marc A.; Peiró Sales, Sandra (Nature Publishing Group, 2018)
    Lamins (A/C and B) are major constituents of the nuclear lamina (NL). Structurally conserved lamina-associated domains (LADs) are formed by genomic regions that contact the NL. Lamins are also found in the nucleoplasm, ...
  • Djebali, Sarah; Merkel, Angelika; Tanzer, Andrea; Lagarde, Julien; Röder, Maik; Curado, Joao; Derrien, Thomas; Ferreira, Pedro G.; González, David; Johnson, Rory; Kingswood, Colin; Ribeca, Paolo; Sammeth, Michael; Skancke, Jorgen; Tilgner, Hagen, 1980-; Guigó Serra, Roderic; Gingeras, Thomas R. (Nature Publishing Group, 2012)
    Eukaryotic cells make many types of primary and processed RNAs that are found either in specific subcellular compartments or throughout the cells. A complete catalogue of these RNAs is not yet available and their characteristic ...
  • Tukiainen, Taru; Guigó Serra, Roderic; MacArthur, Daniel G.; Genotype-Tissue Expression (GTEx) Consortium (Nature Publishing Group, 2017)
    X chromosome inactivation (XCI) silences transcription from one of the two X chromosomes in female mammalian cells to balance expression dosage between XX females and XY males. XCI is, however, incomplete in humans: up to ...
  • Quesada Diez, Rita; Poves Prim, José Ignacio; Iglesias Coma, Mar; Berjano, Enrique J.; Grande Posa, Luís; Burdío Pinilla, Fernando (SpringerOpen, 2016)
    Background: Although radiofrequency-assisted devices have sometimes been used in partial splenectomy, this is not a common technique. This report describes the first case of laparoscopic partial splenectomy using an ...
  • Sebestyén, Endre; Singh, Babita, 1986-; Miñana Gómez, Belén; Pagès Pinós, Amadís; Mateo, Francesc; Pujana, Miguel Angel; Valcárcel, J. (Juan); Eyras Jiménez, Eduardo (Cold Spring Harbor Laboratory Press (CSHL Press), 2016)
    Alternative splicing is regulated by multiple RNA-binding proteins and influences the expression of most eukaryotic genes. However, the role of this process in human disease, and particularly in cancer, is only starting ...
  • Guerra, Beniamino; García Aymerich, Judith; Antó i Boqué, Josep Maria; Puhan, Milo A.; Crystal structure of cold-aminopeptidase from Colwellia psychrerythraea (3CIA) collaborators (BioMed Central, 2018)
    BACKGROUND: External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive pulmonary disease ...
  • Puhan, Milo A.; Hansel, Nadia N; Sobradillo, Patricia; Enright, Paul; Lange, Peter; Hickson, DeMarc; Menezes, Ana M; Riet, Gerben ter; Held, Ulrike; Domingo i Salvany, Antònia; Mosenifar, Zab; Antó i Boqué, Josep Maria; Moons, Karel G M; Kessels, Alphons; García Aymerich, Judith; International COPD Cohorts Collaboration Working Group (BMJ Publishing Group, 2012)
    Background: Little evidence on the validity of simple and widely applicable tools to predict mortality in patients with chronic obstructive pulmonary disease (COPD) exists. Objective: To conduct a large international study ...
  • van Dijk, David; Sharon, Eilon; Lotan Pompan, Maya; Weinberger, Adina; Segal, Eran; Carey, Lucas (Cold Spring Harbor Laboratory Press (CSHL Press), 2017)
    Transcription factors (TFs) are key mediators that propagate extracellular and intracellular signals through to changes in gene expression profiles. However, the rules by which promoters decode the amount of active TF into ...
  • Menashe, Idan; Real, Francisco X.; Kogevinas, Manolis; Serra, Consol; Lloreta, Josep; Rothman, Nathaniel (Public Library of Science (PLoS), 2012)
    Pathway analysis of genome-wide association studies (GWAS) offer a unique opportunity to collectively evaluate genetic variants with effects that are too small to be detected individually. We applied a pathway analysis to ...
  • Pittis, Alexandros, 1982-; Gabaldón Estevan, Juan Antonio, 1973- (Nature Publishing Group, 2016)
    The origin of eukaryotes stands as a major conundrum in biology. Current evidence indicates that the last eukaryotic common ancestor already possessed many eukaryotic hallmarks, including a complex subcellular organization. ...
  • Esquivel López, Argitxu; Pozo Mendoza, Óscar J., 1975-; Garrostas, Lorena; Balcells Aribau, Georgina, 1987-; Gómez Castellà, Cristina, 1985-; Kotronoulas, Aristotelis; Joglar Tamargo, Jesús; Ventura Alemany, Rosa (Wiley, 2017)
    The aim of this study was to evaluate the direct detection of glucuronoconjugated metabolites of metandienone (MTD) and their detection times. Metabolites resistant to enzymatic hydrolysis were also evaluated. Based on the ...
  • Defaus, Sira; Avilés, Manuel; Andreu Martínez, David; Gutiérrez Gallego, Ricardo, 1968- (MDPI, 2018)
    Seminal plasma proteins are relevant for sperm functionality and some appear responsible for establishing sperm interactions with the various environments along the female genital tract towards the oocyte. In recent years, ...
  • Sanz, Ferran; Pastor Maeso, Manuel; Mestres i López, Jordi; Zamora, Ismael (Nature Publishing Group, 2017)
    The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we ...
  • Fuertes, Elaine; Carsin, Anne-Elie; Antó i Boqué, Josep Maria; García Aymerich, Judith (BMJ Publishing Group, 2018)
    OBJECTIVE: We assessed associations between physical activity and lung function, and its decline, in the prospective population-based European Community Respiratory Health Survey cohort. METHODS: FEV1 and FVC were measured ...
  • Casals López, Ferran; Anglada Busquets, Roger; Bonet, Núria; Rasal Soteras, Raquel; van der Gaag, Kristiaan J.; Hoogenboom, Jerry; Solé Morata, Neus, 1988-; Comas, David, 1969-; Calafell i Majó, Francesc (Elsevier, 2017)
    We have genotyped the 58 STRs (27 autosomal, 24 Y-STRs and 7 X-STRs) and 94 autosomal SNPs in Illumina ForenSeq™ Primer Mix A in 88 Spanish Roma (Gypsy) samples and 143 Catalans. Since this platform is based in massive ...
  • López Ruiz, María, 1982-; Mancebo Fernández, Núria; Pérez, Katherine; Serra Saurina, Laura; Benavides, Fernando G. (Fernando García) (Ministerio de Sanidad, Servicios Sociales e Igualdad, 2017)
    FUNDAMENTOS: La mayoría de los estudios sobre las lesiones de tráfico relacionadas con el trabajo (LTT) en España se basan en información de la administración laboral. El objetivo de este estudio fue realizar una descripción ...