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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

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  • Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973- (Elsevier, 2016)
    Clavicipitaceae is a fungal group that comprises species that closely interact with plants as pathogens, parasites or symbionts. A key factor in these interactions is the ability of these fungi to synthesize toxic alkaloid ...
  • Nacht, A. Silvina; Pohl, Andy, 1979-; Zaurín Quer, Roser; Soronellas, Daniel; Quilez Oliete, Javier; Sharma, Priyanka; Wright, Roni H.G.; Beato, Miguel; Vincent, Guillermo P. (Wiley-Blackwell, 2016)
    Eukaryotic gene regulation is associated with changes in chromatin compaction that modulate access to DNA regulatory sequences relevant for transcriptional activation or repression. Although much is known about the mechanism ...
  • Pascual Guàrdia, Sergi, 1979-; Badenes Bonet, Diana; Martín-Ontiyuelo, Clara; Zuccarino, Flavio; Marín Corral, Judith; Rodríguez, Alejandro; Barreiro Portela, Esther; Gea Guiral, Joaquim (Dove Medical Press, 2017)
    BACKGROUND: Vertebral compression fractures (VCF) are common in COPD patients, with osteoporosis being the main cause. The clinical impact of VCF derives mostly from both pain and chest deformity, which may lead to ventilatory ...
  • Ruprecht, Verena; Monzo, Pascale; Ravasio, Andrea; Yue, Zhang; Makhija, Ekta; Strale, Pierre Olivier; Gauthier, Nils; Shivashankar, G. V.; Studer, Vincent; Albiges-Rizo, Corinne; Viasnoff, Virgile (Company of Biologists, 2017)
    Biomimetic materials have long been the (he)art of bioengineering. They usually aim at mimicking in vivo conditions to allow in vitro culture, differentiation and expansion of cells. The past decade has witnessed a ...
  • Subirana, Juan A.; Messeguer, Xavier (MDPI, 2018)
    Repetitive genome regions have been difficult to sequence, mainly because of the comparatively small size of the fragments used in assembly. Satellites or tandem repeats are very abundant in nematodes and offer an excellent ...
  • Erb, Ionas; Notredame, Cedric (Springer, 2016)
    Correlation is ubiquitously used in gene expression analysis although its validity as an objective criterion is often questionable. If no normalization reflecting the original mRNA counts in the cells is available, correlation ...
  • Novoa Pardo, Ana María; Howe, Julia Ward; Malmusi, Davide, 1980-; Díaz Barco, Fernando; Darne, Mercè; Trilla i Bellart, Carme; Bosch, Jordi,; Borre, Carme (BioMed Central, 2015)
    Introduction. Given the increasing number of people in Spain struggling to pay housing-related costs during the economic recession, it is important to assess the health status of these communities as compared to the general ...
  • Dickhaus, Thorsten; Straßburger, Klaus; Schunk, Daniel; Morcillo Suárez, Carlos, 1969-; Illig, Thomas; Navarro i Cuartiellas, Arcadi, 1969- (De Gruyter, 2012)
    We study exact tests for (2 x 2) and (2 x 3) contingency tables, in particular exact chi-squared tests and exact tests of Fisher type. In practice, these tests are typically carried out without randomization, leading to ...
  • Macía, Javier; Solé Vicente, Ricard, 1962- (Public Library of Science (PLoS), 2014)
    Biological systems perform computations at multiple scales and they do so in a robust way. Engineering metaphors have often been used in order to provide a rationale for modeling cellular and molecular computing networks ...
  • Maitre, Léa; de Bont, Jeroen; Casas Sanahuja, Maribel; Robinson, Oliver; Basagaña Flores, Xavier; Borràs, Eva; Bustamante Pineda, Mariona; de Castro, Montserrat; Donaire González, David; Estivill, Xavier, 1955-; Fossati, Serena; González, Juan R.; Hernández-Ferrer, Carles; Júlvez Calvo, Jordi; Manzano Salgado, Cyntia Beatriz, 1987-; Sabidó Aguadé, Eduard, 1981-; Sunyer Deu, Jordi; Tamayo-Uria, Ibon; Urquiza, José M.; van Gent, Diana; Vives Usano, Marta, 1990-; Warembourg, Charline; Nieuwenhuijsen, M.; Vrijheid, Martine (BMJ Publishing Group, 2018)
    PURPOSE: Essential to exposome research is the collection of data on many environmental exposures from different domains in the same subjects. The aim of the Human Early Life Exposome (HELIX) study was to measure and ...
  • Vrijheid, Martine; Robinson, Oliver; Basagaña Flores, Xavier; Bustamante Pineda, Mariona; Casas, Maribel; Estivill, Xavier, 1955-; van Gent, Diana; González Ruiz, Juan Ramón; Júlvez Calvo, Jordi; Kogevinas, Manolis; Sabidó Aguadé, Eduard, 1981-; Sunyer Deu, Jordi; Nieuwenhuijsen, Mark J. (National Institute of Environmental Health Sciences (NIEHS), 2014)
    Background: Developmental periods in early life may be particularly vulnerable to impacts of environmental exposures. Human research on this topic has generally focused on single exposure–health effect relationships. The ...
  • Janich, Peggy, 1981-; Toufighi, Kiana, 1980-; Solanas, Guiomar; Luis, Nuno Miguel, 1982-; Minkwitz, Susann; Serrano Pubull, Luis, 1982-; Lehner, Ben, 1978-; Aznar Benitah, Salvador (Elsevier, 2013)
    Human skin copes with harmful environmental factors that are circadian in nature, yet how circadian rhythms modulate the function of human epidermal stem cells is mostly unknown. Here we show that in human epidermal stem ...
  • Dall'Olio, Giovanni Marco, 1983-; Bertranpetit, Jaume, 1952-; Wagner, Andreas; Laayouni, Hafid, 1968- (Public Library of Science (PLoS), 2014)
    Genotype networks are a concept used in systems biology to study sets of genotypes having the same phenotype, and the ability of these to bring forth novel phenotypes. In the past they have been applied to determine the ...
  • Colonna, Vincenza; Ayub, Qasim; Cheng, Yuan; Pagani, Luca; Luisi, Pierre, 1985-; Pybus Oliveras, Marc, 1985-; Garrison, Erik; Xue, Yali; Tyler-Smith, Chris; The 1000 Genomes Project Consortium (BioMed Central, 2014)
    Background: Population differentiation has proved to be effective for identifying loci under geographically localized positive selection, and has the potential to identify loci subject to balancing selection. We have ...
  • Gaidt, Moritz M.; Ebert, Thomas S.; Chauhan, Dhruv; Schmidt, Tobias; Schmid-Burgk, Jonathan L.; Rapino, Francesca, 1982-; Robertson, Avril A. B.; Cooper, Matthew A.; Graf, T. (Thomas); Hornung, Veit (Elsevier, 2016)
    Interleukin-1β (IL-1β) is a cytokine whose bioactivity is controlled by activation of the inflammasome. However, in response to lipopolysaccharide, human monocytes secrete IL-1β independently of classical inflammasome ...
  • Planagumà, Jesús; Leypoldt, Frank; Mannara, Francesco; Gutiérrez Cuesta, Javier; Martín García, Elena, 1975-; Aguilar, Esther; Titulaer, Maarten J.; Petit-Pedrol, Mar; Jain, Ankit; Balice-Gordon, Rita; Lakadamyali, Melike; Graus, Francesc; Maldonado, Rafael, 1961-; Dalmau, Josep (Oxford University Press, 2015)
    Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder that associates with prominent memory and behavioural deficits. Patients' antibodies react with the N-terminal domain of the ...
  • Sanchez-Delgado, Marta; Court, Franck; Vidal, Enrique; Medrano, Jose; Monteagudo-Sánchez, Ana; Martin-Trujillo, Alex; Tayama, Chiharu; Iglesias-Platas, Isabel; Kondova, Ivanela; Bontrop, Ronald E.; Poo-Llanillo, Maria Eugenia; Marquès i Bonet, Tomàs, 1975-; Nakabayashi, Kazuhiko; Simón, Carlos; Monk, David (Public Library of Science (PLoS), 2016)
    Thousands of regions in gametes have opposing methylation profiles that are largely resolved during the post-fertilization epigenetic reprogramming. However some specific sequences associated with imprinted loci survive ...
  • Papaseit Fontanet, Esther; Pérez Mañá, Clara; Mateus Rodriguez, Julian Andrés; Pujadas Bastardes, Mitona; Fonseca Casals, Francina, 1972-; Torrens, Marta; Olesti Muñoz, Eulàlia; Torre Fornell, Rafael de la; Farré Albaladejo, Magí (Nature Publishing Group, 2016)
    Mephedrone (4-methylmethcathinone) is a novel psychoactive substance popular among drug users because it displays similar effects to MDMA (3,4-methylenedioxymethamphetamine, ecstasy). Mephedrone consumption has been ...
  • Conde Pueyo, Núria, 1983-; Munteanu, Andreea; Solé Vicente, Ricard, 1962-; Rodríguez Caso, Carlos (BioMed Central, 2009)
    Background: Two genes are called synthetic lethal (SL) if mutation of either alone is not lethal, but mutation of both leads to death or a significant decrease in organism's fitness. The detection of SL gene pairs constitutes ...
  • Bouchnita, Anass; Bocharov, Gennady A.; Meyerhans, Andreas; Volpert, Vitaly (BioMed Central, 2017)
    BACKGROUND: Moving from the molecular and cellular level to a multi-scale systems understanding of immune responses requires the development of novel approaches to integrate knowledge and data from different biological ...

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