Benvinguts al Repositori Digital de la UPF

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

Ordena per: Ordre: Resultats:

  • Franco-Jarava, C.; Comas, David, 1969-; Orren, Ann; Hernández-González, M.; Colobran, R. (Wiley, 2017)
    Complement C5 deficiency (C5D) is a rare primary immunodeficiency associated with recurrent infections, particularly meningitis, by Neisseria species. To date, studies to elucidate the molecular basis of hereditary C5D ...
  • Morales, Lucia; Noel, Benjamin; Porcel, Betina; Marcet Houben, Marina; Hullo, Marie-Françoise; Sacerdot, Christine; Tekaia, Fredj; Leh-Louis, Véronique; Despons, Laurence; Khanna, Varun; Aury, Jean-Marc; Barbe, Valérie; Coloux, Arnaud; Labadie, Karine; Pelletier, Eric; Souciet, Jean-Luc; Boekhout, Teun; Gabaldón Estevan, Juan Antonio, 1973-; Wincker, Patrick; Dujon, Bernard (Oxford University Press, 2013)
    The numerous yeast genome sequences presently available provide a rich source of information for functional as well as evolutionary genomics but unequally cover the large phylogenetic diversity of extant yeasts. We present ...
  • Soriano, Miguel C.; García Ojalvo, Jordi; Mirasso, Claudio R.; Fischer, Ingo (American Physical Society, 2013)
    Complex phenomena in photonics, in particular, dynamical properties of semiconductor lasers due to delayed coupling, are reviewed. Although considered a nuisance for a long time, these phenomena now open interesting ...
  • Sailani, M. Reza; Rabionet, Kelly; Serra Juhé, Clara, 1984-; Pérez Jurado, Luis Alberto; Estivill, Xavier, 1955-; Antonarakis, Stylianos E. (Cold Spring Harbor Laboratory Press (CSHL Press), 2013)
    Congenital heart defect (CHD) occurs in 40% of Down syndrome (DS) cases. While carrying three copies of chromosome 21 increases the risk for CHD, trisomy 21 itself is not sufficient to cause CHD. Thus, additional genetic ...
  • Mariotti, Marco, 1984-; Ridge, Perry G.; Zhang, Yan; Lobanov, Alexei V.; Pringle, Thomas H.; Guigó Serra, Roderic; Hatfield, Dolph L.; Gladyshev, Vadim N. (Public Library of Science (PLoS), 2012)
    BACKGROUND: Selenium is an essential trace element in mammals due to its presence in proteins in the form of selenocysteine (Sec). Human genome codes for 25 Sec-containing protein genes, and mouse and rat genomes for 24. ...
  • Tamborero Noguera, David; González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Déu Pons, Jordi; Kandoth, Cyriac; Reimand, Jüri; Lawrence, Michael S.; Getz, Gad; Bader, Gary D.; Ding, Li; López Bigas, Núria (Nature Publishing Group, 2013)
    With the ability to fully sequence tumor genomes/exomes, the quest for cancer driver genes can now be undertaken in an unbiased manner. However, obtaining a complete catalog of cancer genes is difficult due to the heterogeneous ...
  • Invergo, Brandon M., 1982-; Dell'Orco, Daniele; Montanucci, Ludovica, 1978-; Koch, Karl-Wilhelm; Bertranpetit, Jaume, 1952- (Royal Society of Chemistry, 2014)
    Vertebrate visual phototransduction is perhaps the most well-studied G-protein signaling pathway. A wealth of available biochemical and electrophysiological data has resulted in a rich history of mathematical modeling of ...
  • Guigó Serra, Roderic (Centre de Supercomputació de Catalunya, 1995)
  • Aguilar, Daniel; Pinart, Mariona; Benet, Marta; García Aymerich, Judith; González Ruiz, Juan Ramón; Guerra, Stefano; Kogevinas, Manolis; Sunyer Deu, Jordi; Valverde, Sergi; Oliva Miguel, Baldomero; Antó i Boqué, Josep Maria (Public Library of Science (PLoS), 2017)
    Background: The mechanisms explaining the co-existence of asthma, eczema and rhinitis (allergic multimorbidity) are largely unknown. We investigated the mechanisms underlying multimorbidity between three main allergic ...
  • González-Pérez, Abel; López Bigas, Núria (Nature Research, 2013)
    The International Cancer Genome Consortium (ICGC) aims to catalog genomic abnormalities in tumors from 50 different cancer types. Genome sequencing reveals hundreds to thousands of somatic mutations in each tumor but only ...
  • Santesmasses Ruiz, Didac, 1978-; Mariotti, Marco, 1984-; Guigó Serra, Roderic (Public Library of Science (PLoS), 2017)
    Selenocysteine (Sec) is known as the 21st amino acid, a cysteine analogue with selenium replacing sulphur. Sec is inserted co-translationally in a small fraction of proteins called selenoproteins. In selenoprotein genes, ...
  • Sardanyés i Cayuela, Josep; Bonforti, Adriano; Conde Pueyo, Núria, 1983-; Solé Vicente, Ricard, 1962-; Macía, Javier (Frontiers, 2015)
    Cells are complex machines capable of processing information by means of an entangled network of molecular interactions. A crucial component of these decision-making systems is the presence of memory and this is also a ...
  • Saravia, Rocío; Ten-Blanco, Marc; Julià Hernández, Marina; Gagliano, Humberto; Andero, Raül; Armario García, Antonio; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2019)
    Δ9-tetrahydrocannabinol (THC) consumption during adolescence is reported to be a risk factor for the appearance of psychiatric disorders later in life. The interaction between genetic or environmental events and cannabinoid ...
  • Ronda-Pérez, Elena; Agudelo Suárez, Andrés A; López Jacob, María José; García, Ana M.; Benavides, Fernando G. (Fernando García) (Ministerio de Sanidad y Consumo, 2014)
    Fundamentos: La relación entre inmigración, trabajo y salud constituye uno de los retos más importantes en salud laboral y más concretamente en España por el importante incremento de proporción inmigrante acontecido en el ...
  • Hung, Wei-Chien; Yang, Jessica R.; Yankaskas, Christopher L.; Wong, Bin Sheng; Wu, Pei-Hsun; Pardo Pastor, Carlos; Serra Pascual, Selma A., 1981-; Chiang, Meng-Jung; Gu, Zhizhan; Wirtz, Denis; Valverde, M. A. (Miguel Ángel), 1963-; Zhang, Jin; Konstantopoulos, Konstantinos (Elsevier, 2016)
    Cells adopt distinct signaling pathways to optimize cell locomotion in different physical microenvironments. However, the underlying mechanism that enables cells to sense and respond to physical confinement is unknown. ...
  • Torrent, Marc; Andreu Martínez, David; Nogués, Victòria M; Boix, Ester (Public Library of Science (PLoS), 2011)
    The increasing rate in antibiotic-resistant bacterial strains has become an imperative health issue. Thus, pharmaceutical industries have focussed their efforts to find new potent, non-toxic compounds to treat bacterial ...
  • Lang, Michael; Hadzhiev, Yavor; Siegel, Nicol; Amemiya, Chris T; Parada, Carolina; Strähle, Uwe; Becker, May-Britt; Müller, Ferenc; Meyer, Axel (BioMed Central, 2010)
    Background: The modern coelacanth (Latimeria) is the extant taxon of a basal sarcopterygian lineage and sister group to tetrapods. Apart from certain apomorphic traits, its morphology is characterized by a high degree of ...
  • Guigó Serra, Roderic; Blanco, Enrique; Pignatelli, Miguel; Punset, Adrià; Pérez-Lluch, Sílvia; Serras Rigalt, Florenci; Corominas Guiu, Montserrat (BioMed Central, 2008)
    BACKGROUND: The trithorax group (trxG) and Polycomb group (PcG) proteins are responsible for the maintenance of stable transcriptional patterns of many developmental regulators. They bind to specific regions of DNA and ...
  • Solana, Jordi; Irimia, Manuel; Ayoub, Salah; Rodriguez Orejuela, Marta; Zywitza, Vera; Jens, Marvin; Tapial, Javier; Ray, Debashish; Morris, Quaid; Hughes, Timothy R.; Blencowe, Benjamin J.; Rajewsky, Nicolaus (eLife, 2016)
    In contrast to transcriptional regulation, the function of alternative splicing (AS) in stem cells is poorly understood. In mammals, MBNL proteins negatively regulate an exon program specific of embryonic stem cells; ...
  • Malagarriga, Daniel; Villa, Alessandro E. P.; García Ojalvo, Jordi; Pons, Antonio J. (American Institute of Physics (AIP), 2017)
    Synchronization within the dynamical nodes of a complex network is usually considered homogeneous through all the nodes. Here we show, in contrast, that subsets of interacting oscillators may synchronize in different ways ...