Benvinguts al Repositori Digital de la UPF

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

Ordena per: Ordre: Resultats:

  • Torrent, Marc; Andreu Martínez, David; Nogués, Victòria M; Boix, Ester (Public Library of Science (PLoS), 2011)
    The increasing rate in antibiotic-resistant bacterial strains has become an imperative health issue. Thus, pharmaceutical industries have focussed their efforts to find new potent, non-toxic compounds to treat bacterial ...
  • Lang, Michael; Hadzhiev, Yavor; Siegel, Nicol; Amemiya, Chris T; Parada, Carolina; Strähle, Uwe; Becker, May-Britt; Müller, Ferenc; Meyer, Axel (BioMed Central, 2010)
    Background: The modern coelacanth (Latimeria) is the extant taxon of a basal sarcopterygian lineage and sister group to tetrapods. Apart from certain apomorphic traits, its morphology is characterized by a high degree of ...
  • Guigó Serra, Roderic; Blanco, Enrique; Pignatelli, Miguel; Punset, Adrià; Pérez-Lluch, Sílvia; Serras Rigalt, Florenci; Corominas Guiu, Montserrat (BioMed Central, 2008)
    BACKGROUND: The trithorax group (trxG) and Polycomb group (PcG) proteins are responsible for the maintenance of stable transcriptional patterns of many developmental regulators. They bind to specific regions of DNA and ...
  • Solana, Jordi; Irimia, Manuel; Ayoub, Salah; Rodriguez Orejuela, Marta; Zywitza, Vera; Jens, Marvin; Tapial, Javier; Ray, Debashish; Morris, Quaid; Hughes, Timothy R.; Blencowe, Benjamin J.; Rajewsky, Nicolaus (eLife, 2016)
    In contrast to transcriptional regulation, the function of alternative splicing (AS) in stem cells is poorly understood. In mammals, MBNL proteins negatively regulate an exon program specific of embryonic stem cells; ...
  • Malagarriga, Daniel; Villa, Alessandro E. P.; García Ojalvo, Jordi; Pons, Antonio J. (American Institute of Physics (AIP), 2017)
    Synchronization within the dynamical nodes of a complex network is usually considered homogeneous through all the nodes. Here we show, in contrast, that subsets of interacting oscillators may synchronize in different ways ...
  • Garcia Etxebarria, Koldo; García Garcerà, Marc; Calafell i Majó, Francesc (BioMed Central, 2014)
    Background: Metagenomics is the genomic study of uncultured environmental samples, which has been greatly facilitated by the advent of shotgun-sequencing technologies. One of the main focuses of metagenomics is the discovery ...
  • Núñez Ollé, Marc, 1984-; Jung, Carole; Terré, Berta; Balsiger, Norman A.; Plata, Cristina; Roset i Huguet, Ramon; Pardo Pastor, Carlos; Garrido, Marta; Rojas, Santiago; Alameda Quitllet, Francisco; Lloreta, Josep, 1958-; Martín Caballero, Juan; Flores, Juana M.; Stracker, Travis; Valverde, M. A. (Miguel Ángel), 1963-; Muñoz López, Francisco José, 1964-; Gil Gómez, Gabriel (Impact Journals, 2017)
    Cyclin O (encoded by CCNO) is a member of the cyclin family with regulatory functions in ciliogenesis and apoptosis. Homozygous CCNO mutations have been identified in human patients with Reduced Generation of Multiple ...
  • Ruetz, Tyson Joel; Pfisterer, Ulrich; Di Stefano, Bruno, 1984-; Ashmore, James; Beniazza, Meryam; Tian, Tian V.; Kaemena, Daniel F.; Tosti, Luca; Tan, Wenfang; Manning, Jonathan R.; Chantzoura, Eleni; Ottosson, Daniella Rylander; Collombet, Samuel; Johnsson, Anna E.; Cohen, Erez; Yusa, Kosuke; Linnarsson, Sten; Graf, T. (Thomas); Parmar, Malin; Kaji, Keisuke (Elsevier, 2017)
    Reprogramming of cellular identity using exogenous expression of transcription factors (TFs) is a powerful and exciting tool for tissue engineering, disease modeling, and regenerative medicine. However, generation of desired ...
  • Alberdi Ibarzabal, Maria, 1986-; Iglesias, Marcos; Tejedor Vaquero, Sonia; Merino, Ramón; López Rodríguez, M. Cristina; Aramburu, José (Aramburu Beltrán) (Nature Publishing Group, 2017)
    Stress-activated transcription factors influence T-cell function in different physiopathologic contexts. NFAT5, a relative of nuclear factor κB and the calcineurin-activated NFATc transcription factors, protects mammalian ...
  • Benavides, Fernando G. (Fernando García); Villabí, Joan R. (Ministerio de Sanidad y Consumo, 2014)
    El impacto del alcohol en la salud pública es notable: el estudio de la carga global de enfermedad de la Organización Mundial de la Salud lo considera uno de los principales factores de riesgo, especialmente en los países ...
  • Fonseca Casals, Francina, 1972-; Torre Fornell, Rafael de la; Díaz, Laura; Pastor, Antonio; Cuyàs, Elisabet; Pizarro Lozano, Mª Nieves; Khymenets, Olha, 1974-; Farré Albaladejo, Magí; Torrens, Marta (Public Library of Science (PLoS), 2011)
    Although the efficacy of methadone maintenance treatment (MMT) in opioid dependence disorder has been well established, the influence of methadone pharmacokinetics in dose requirement and clinical outcome remains controversial. ...
  • Serra Juhé, Clara, 1984-; Rodríguez Santiago, Benjamín; Cuscó Martí, Ivon, 1973-; Vendrell, Teresa; Camats, Núria; Torán, Núria; Pérez Jurado, Luis Alberto (Public Library of Science (PLoS), 2012)
    Background: Congenital malformations are present in approximately 2–3% of liveborn babies and 20% of stillborn fetuses. The mechanisms underlying the majority of sporadic and isolated congenital malformations are poorly ...
  • Nadal Ribelles, Mariona, 1984-; Solé, Carme; Xu, Zhenyu; Steinmetz, Lars M.; Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Elsevier, 2014)
    Genomic analysis has revealed the existence of a large number of long noncoding RNAs (lncRNAs) with different functions in a variety of organisms, including yeast. Cells display dramatic changes of gene expression upon ...
  • Solé, Carme; Nadal Ribelles, Mariona, 1984-; Kraft, Claudine; Peter, Matthias; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Nature Publishing Group, 2011)
    Protein ubiquitylation is a key process in the regulation of many cellular processes. The balance between the activity of ubiquitin ligases and that of proteases controls the level of ubiquitylation. In response to ...
  • Nicolay, Brandon N.; Bayarmagnai, Battuya; Islam, Abul, 1978-; López Bigas, Núria; Frolov, Maxim V. (Cold Spring Harbor Laboratory Press (CSHL Press), 2011)
    The Hippo signaling pathway regulates organ size homeostasis, while its inactivation leads to severe hyperplasia in flies and mammals. The transcriptional coactivator Yorkie (Yki) mediates transcriptional output of the ...
  • Castro, Patricio A.; Ramírez, Alejandra; Sepúlveda, Fernando J.; Peters, Christian; Fierro, Humberto; Waldron, Javier; Luza, Sandra; Fuentealba, Jorge; Muñoz López, Francisco José, 1964-; De Ferrari, Giancarlo V.; Bush, Ashley I.; Aguayo, Luis G.; Opazo, Carlos (Frontiers, 2014)
    Extracellular and intracellular copper and zinc regulate synaptic activity and plasticity, which may impact brain functionality and human behavior. We have found that a metal coordinating molecule, Neocuproine, transiently ...
  • Martin-Trujillo, Alex; Vidal Ocabo, Enrique; Monteagudo-Sánchez, Ana; Sanchez-Delgado, Marta; Moran, Sebastian; Hernández Mora, José Ramón; Heyn, Holger; Guitart, Miriam; Esteller, Manel; Monk, David (Nature Publishing Group, 2017)
    It has been postulated that imprinting aberrations are common in tumors. To understand the role of imprinting in cancer, we have characterized copy-number and methylation in over 280 cancer cell lines and confirm our ...
  • Gazave, Elodie; Darre, Fleur; Morcillo Suárez, Carlos; Petit, Natalia; Carreño, Angel; Marigorta, Urko M.; Ryder, Oliver A.; Blancher, Antoine; Rocchi, Mariano; Bosch Fusté, Elena; Baker, Carl; Marquès i Bonet, Tomàs, 1975-; Eichler, Evan E.; Navarro i Cuartiellas, Arcadi, 1969- (Cold Spring Harbor Laboratory Press (CSHL Press), 2011)
    Copy number variants (CNVs) are increasingly acknowledged as an important source of evolutionary novelties in the human lineage. However, our understanding of their significance is still hindered by the lack of primate CNV ...
  • Valle Pérez, Beatriz del; Casagolda, David; Lugilde, Ero; Valls, Gabriela; Codina, Montserrat; Dave, Natàlia; García de Herreros, Antonio; Duñach, Mireia (Company of Biologists, 2016)
    There was an error published in J. Cell Sci. 124, 2298–2309.
  • Twose, Jorge; Schiaffino, Anna; García Martínez, Montse; Borràs, Josep M.; Fernández, Esteve (BioMed Central, 2007)
    Background: To describe the socio-demographic factors associated with exposure to second-hand smoke (SHS) in different settings (home, leisure, and workplace). Methods: We analysed cross-sectional data on self-reported SHS ...