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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

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  • Herráiz Yebes, Alba, 1984-; Bellés, Xavier, 1952-; Piulachs i Bagà, M. Dolors (Elsevier, 2014)
    Epigenetic modifications play key roles in transcriptional regulation. Trimethylation of histone 3 lysine 9 (H3K9me3) is one of the most widely studied histone post-translational modifications, and has been linked to ...
  • Bousquet, Jean; Antó i Boqué, Josep Maria; Senn, A. (BioMed Central, 2017)
    A Good Practice is a practice that works well, produces good results, and is recommended as a model. MACVIA-ARIA Sentinel Network (MASK), the new Allergic Rhinitis and its Impact on Asthma (ARIA) initiative, is an example ...
  • Font-Burgada, Joan; Reina García, Óscar, 1976-; Rossell, David; Azorín Marín, Fernando (Oxford University Press, 2014)
    Development of tools to jointly visualize the genome and the epigenome remains a challenge. chroGPS is a computational approach that addresses this question. chroGPS uses multidimensional scaling techniques to represent ...
  • Corominas Murtra, Bernat; Sànchez Fibla, Martí; Valverde, Sergi; Solé Vicente, Ricard, 1962- (Royal Society, 2018)
    The emergence of syntax during childhood is a remarkable example of how complex correlations unfold in nonlinear ways through development. In particular, rapid transitions seem to occur as children reach the age of two, ...
  • Bogu, Gireesh K., 1984-; Vizán, Pedro; Stanton, Lawrence W.; Beato, Miguel; Di Croce, Luciano; Marti-Renom, Marc A. (American Society for Microbiology, 2015)
    Discovering and classifying long noncoding RNAs (lncRNAs) across all mammalian tissues and cell lines remains a major challenge. Previously, mouse lncRNAs were identified using transcriptome sequencing (RNA-seq) data from ...
  • Aranda Aragón, Sergio; Alcaine Colet, Anna; Blanco, Enrique; Borràs, Eva; Caillot, Claire; Sabidó Aguadé, Eduard, 1981-; Di Croce, Luciano (American Association for the Advancement of Science (AAAS), 2019)
    Profiling the chromatin-bound proteome (chromatome) in a simple, direct, and reliable manner might be key to uncovering the role of yet uncharacterized chromatin factors in physiology and disease. Here, we have designed ...
  • Mulero, María Carmen; Islam, Abul, 1978-; Margalef González, Pol, 1985-; Pecoraro, Matteo, 1984-; Toll Abelló, Agustín; Drechsel, Nils Jan Daniel, 1980-; Charneco, Cristina; Bellora Pereyra, Nicolás; Gallardo Hernández, Fernando; López Arribillaga, Erika; Asensio Juan, Elena; Rodilla, Verónica; González, Jessica; Iglesias Coma, Mar; Albà Soler, Mar; Di Croce, Luciano; Villà i Freixa, Jordi; López Bigas, Núria; Keyes, William M., 1973-; Bigas Salvans, Anna; Espinosa Blay, Lluís (Elsevier, 2013)
    IκB proteins are the primary inhibitors of NF-κB. Here, we demonstrate that sumoylated and phosphorylated IκBα accumulates in the nucleus of keratinocytes and interacts with histones H2A and H4 at the regulatory region of ...
  • Segalés Dalmau, Jessica; Islam, Abul, 1978-; Kumar, Roshan; Liu, Qi-Cai; Sousa-Victor, Pedro; Dilworth, F. Jeffrey; Ballestar, Esteban; Perdiguero, Eusebio, 1968-; Muñoz Cánoves, Pura, 1962- (BioMed Central, 2016)
    Background: Extracellular stimuli induce gene expression responses through intracellular signaling mediators. The p38 signaling pathway is a paradigm of the mitogen-activated protein kinase (MAPK) family that, although ...
  • Vona, Chiara Di; Bezdan, Daniela; Islam, Abul, 1978-; Salichs Fradera, Eulàlia; López Bigas, Núria; Ossowski, Stephan; Luna, Susana de la (Elsevier, 2015)
    DYRK1A is a dosage-sensitive protein kinase that fulfills key roles during development and in tissue homeostasis, and its dysregulation results in human pathologies. DYRK1A is present in both the nucleus and cytoplasm of ...
  • Monyarch, Gemma; De Castro Reis, Fernanda; Zock, Jan-Paul; Giraldo, Jesús; Pozo Rodríguez, Francisco; Espinosa Díaz, Ana; Rodríguez Trigo, Gema; Gómez, Federico P.; Antó i Boqué, Josep Maria; Coll, Maria; Barberà, Joan Albert; Fuster, Carme (Public Library of Science (PLoS), 2013)
    Background: In a previous study, we showed that individuals who had participated in oil clean-up tasks after the wreckage of the Prestige presented an increase of structural chromosomal alterations two years after the acute ...
  • Zapata Ortiz, Luis, 1985-; Ding, Jia; Willing, Eva-Maria; Hartwig, Benjamin; Bezdan, Daniela; Jiao, Wen-Biao; Patel, Vipul; Velikkakam, James Geo; Koornneef, Maarten; Ossowski, Stephan; Schneeberger, Korbinian (National Academy of Sciences, 2016)
    Resequencing or reference-based assemblies reveal large parts of the small-scale sequence variation. However, they typically fail to separate such local variation into colinear and rearranged variation, because they usually ...
  • Roca, Josep; Vargas, Claudia; Cano, Isaac; Selivanov, Vitaly; Barreiro Portela, Esther; Maier, Dieter; Falciani, Francesco; Wagner, Peter; Cascante, Marta; García Aymerich, Judith; Kalko, Susana G.; Marin de Mas, Igor; Tegnér, Jesper; Escarabill, Joan; Agustí, Alvar; Gomez Cabrero, David; Synergy-COPD consortium (BioMed Central, 2014)
    Background and hypothesis: Heterogeneity in clinical manifestations and disease progression in Chronic Obstructive Pulmonary Disease (COPD) lead to consequences for patient health risk assessment, stratification and ...
  • Perdiguero, Eusebio, 1968-; Serrano Sánchez, Antonio L.; Muñoz Cánoves, Pura, 1962- (Elsevier, 2017)
    Fibro/adipogenic progenitors (FAPs) are emerging as crucial regulators of fibrous and fat deposits during skeletal muscle regeneration. In a recent issue of Cell, Kopinke et al. (2017) report that primary cilia induce the ...
  • González-Pérez, Abel (BioMed Central, 2016)
    BACKGROUND: Large tumor genome sequencing projects have now uncovered a few hundred genes involved in the onset of tumorigenesis, or drivers, in some two dozen malignancies. One of the main challenges emerging from this ...
  • Rubio Martínez, Mercedes, 1980-; Bustamante Pineda, Mariona; Hernandez-Ferrer, Carles, 1987-; Fernández-Orth, Dietmar; Pantano Rubiño, Lorena, 1982-; Sarria-Trujillo, Yaris; Piqué-Borras, Maria; Vellve del Amo, Kilian; Agramunt, Silvia; Carreras Collado, Ramón; Estivill, Xavier, 1955-; González Ruiz, Juan Ramón; Mayor, Alfredo (Public Library of Science (PLoS), 2018)
    Circulating small RNAs, including miRNAs but also isomiRs and other RNA species, have the potential to be used as non-invasive biomarkers for communicable and non-communicable diseases. This study aims to characterize and ...
  • Frounfelker, Rochelle; Gilman, Stephen E.; Betancourt, Theresa S.; Aguilar Gaxiola, Sergio; Alonso Caballero, Jordi; Bromet, Evelyn J.; Bruffaerts, Ronny; De Girolamo, Giovanni; Gluzman, Semyon; Gureje, Oye; Karam, Elie G.; Lee, Sing; Lépine, Jean-Pierre; Ono, Yutaka; Pennell, Beth-Ellen; Popovici, Daniela G.; ten Have, Margreet; Kessler, Ronald C.; WHO World Mental Health Survey Collaborators (Springer, 2018)
    PURPOSE: Understanding the effects of war on mental disorders is important for developing effective post-conflict recovery policies and programs. The current study uses cross-sectional, retrospectively reported data collected ...
  • Curto, Josué; Valle Pérez, Beatriz del; Villarroel, Aida; Fuertes, Guillem; Vinyoles, Meritxell; Peña, Raúl; García de Herreros, Antonio; Duñach, Mireia (Wiley, 2018)
    Canonical and noncanonical Wnt pathways share some common elements but differ in the responses they evoke. Similar to Wnt ligands acting through the canonical pathway, Wnts that activate the noncanonical signaling, such ...
  • Sarquis, Leila M. M.; Vargas-Prada Figueroa, Sergio, 1976-; Serra, Consol; Delclòs i Clanchet, Jordi, 1956-; Benavides, Fernando G. (Fernando García); Kogevinas, Manolis; Salazar Vega, Eduardo J. (Wolters Kluwer (LWW), 2016)
    To inform case definition for neck/shoulder pain in epidemiological research, we compared levels of disability, patterns of association, and prognosis for pain that was limited to the neck or shoulders (LNSP) and more ...
  • Dadvand, Payam; Basagaña Flores, Xavier; Sartini, Claudio; Figueras, Francesc; Vrijheid, Martine; De Nazelle, Audrey; Sunyer Deu, Jordi; Nieuwenhuijsen, Mark J. (National Institute of Environmental Health Sciences (NIEHS), 2011)
    Background: Although future climate is predicted to have more extreme heat conditions, the available evidence on the impact of these conditions on pregnancy length is very scarce and inconclusive. Objectives: We investigated ...
  • Sánchez-Rodríguez, María Dolores; Annweiler, Cédric; Ronquillo-Moreno, Natalia; Tortosa Rodríguez, Andrea; Guillén-Solà, Anna; Vázquez Ibar, Olga; Escalada, Ferran; Muniesa Portoles, Josep M.; Marco Navarro, Ester (Elsevier, 2018)
    BACKGROUND: Malnutrition is a prevalent condition related to adverse outcomes in older people. Our aim was to compare the diagnostic capacity of the malnutrition criteria of the European Society of Parenteral and Enteral ...

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