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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

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  • Alioto, Tyler; Ngai, John (BioMed Central, 2005)
    Background: Vertebrate odorant receptors comprise three types of G protein-coupled receptors: the OR, V1R and V2R receptors. The OR superfamily contains over 1,000 genes in some mammalian species, representing the largest ...
  • Almeida Carvalho, Maria J.; Braun, Andreas, 1983-; Louis, Matthieu; Zlatic, Marta (Company of Biologists, 2017)
    Mapping brain function to brain structure is a fundamental task for neuroscience. For such an endeavour, the Drosophila larva is simple enough to be tractable, yet complex enough to be interesting. It features about 10,000 ...
  • Marquès i Bonet, Tomàs, 1975-; Girirajan, Santhosh; Eichler, Evan E. (Elsevier, 2009)
    Duplicated sequences are substrates for the emergence of new genes and are an important source of genetic instability associated with rare and common diseases. Analyses of primate genomes have shown an increase in the ...
  • Joaquin i Caudet, Manel; Gubern, Albert; González Nuñez, Daniel; Ruiz, E. Josué; Ferreiro Neira, Isabel; Nadal Clanchet, Eulàlia de; Nebreda, Ángel R.; Posas Garriga, Francesc (Nature Publishing Group, 2012)
    The p57(Kip2) cyclin-dependent kinase inhibitor (CDKi) has been implicated in embryogenesis, stem-cell senescence and pathologies, but little is known of its role in cell cycle control. Here, we show that p57(Kip2) is ...
  • Mularoni, Loris; Ramos-Rodríguez, Mireia; Pasquali, Lorenzo (Frontiers, 2017)
    The pancreatic islet is a highly specialized tissue embedded in the exocrine pancreas whose primary function is that of controlling glucose homeostasis. Thus, understanding the transcriptional control of islet-cell may ...
  • Vicario Orri, Elena, 1989-; Opazo, Carlos M.; Muñoz López, Francisco José, 1964- (IOS Press, 2015)
    Neurons communicate in the nervous system by carrying out information along the length of their axons to finally transmit it at the synapse. Proper function of axons and axon terminals relies on the transport of proteins, ...
  • Stanley, Nathaniel H., 1983-; Pardo, Leonardo; De Fabritiis, Gianni (Nature publishing group, 2016)
    The binding process through the membrane bilayer of lipid-like ligands to a protein target is an important but poorly explored recognition process at the atomic level. In this work we succeeded in resolving the binding of ...
  • Jara, Mónica; Vivancos Prellezo, Ana; Calvo, Isabel A.; Moldón Vara, Alberto; Sansó Martínez, Miriam, 1979-; Hidalgo Hernando, Elena (American Society for Cell Biology, 2007)
    Peroxiredoxins are known to interact with hydrogen peroxide (H2O2) and to participate in oxidant scavenging, redox signal transduction, and heat-shock responses. The two-cysteine peroxiredoxin Tpx1 of Schizosaccharomyces ...
  • Barreiro Portela, Esther; Puig Vilanova, Ester, 1987-; Salazar Degracia, Anna; Pascual Guàrdia, Sergi, 1979-; Casadevall Fusté, Carme; Gea Guiral, Joaquim (American Physiological Society, 2018)
    Peripheral muscle weakness and mass loss are characteristic features in severe chronic obstructive pulmonary disease (COPD). We hypothesized that the phosphodiesterase (PDE)-4 inhibitor roflumilast-induced cAMP may ameliorate ...
  • Gal-Mark, Nurit; Schwartz, Schraga; Ram, Oren; Eyras Jiménez, Eduardo; Ast, Gil (Public Library of Science (PLoS), 2009)
    More than 5% of alternatively spliced internal exons in the human genome are derived from Alu elements in a process termed exonization. Alus are comprised of two homologous arms separated by an internal polypyrimidine tract ...
  • Santanach Buxaderas, Alexandra, 1988-; Blanco, Enrique; Jiang, Hua; Molloy, Kelly R.; Sansó Martínez, Miriam, 1979-; LaCava, John; Morey Ramonell, Lluís; Di Croce, Luciano (Nature Publishing Group, 2017)
    Polycomb group proteins (PcG) are transcriptional repressors that control cell identity and development. In mammals, five different CBX proteins associate with the core Polycomb repressive complex 1 (PRC1). In mouse embryonic ...
  • Orefice, Carlo; Pérez Sánchez, Jorge; Baños i Díez, Josep Eladi (Elsevier, 2019)
    INTRODUCTION: There is an increasing interest in the usefulness of humanities to improve the training of medical students. In this article, an analysis is made of the presence of humanities subjects in medical curricula ...
  • de Graaf, Ron; Kessler, Ronald C.; Fayyad, John; ten Have, Margreet; Alonso Caballero, Jordi; Angermeyer, Matthias C.; Borges, Guilherme; Demyttenaere, Koen; Gasquet, Isabelle; Girolamo, Giovanni de; Haro Abad, Josep Maria; Jin, Robert; Karam, Elie G.; Ormel, Johan; Posada Villa, José (BMJ Publishing Group, 2008)
    OBJECTIVES: To estimate the prevalence and workplace consequences of adult attention-deficit/hyperactivity disorder (ADHD). METHODS: An ADHD screen was administered to 18-44-year-old respondents in 10 national surveys in ...
  • Gimeno Santos, Elena, 1980-; Serra Pons, Ignasi; Basagaña Flores, Xavier; García Aymerich, Judith; PROactive consortium (European Respiratory Society, 2015)
    No current patient-centred instrument captures all dimensions of physical activity in chronic obstructive pulmonary disease (COPD). Our objective was item reduction and initial validation of two instruments to measure ...
  • Trincado Alonso, Juan Luis; Sebestyén, Endre; Pagès Pinós, Amadís; Eyras Jiménez, Eduardo (BioMed Central, 2016)
    Background: Phenotypic changes during cancer progression are associated with alterations in gene expression, which can be exploited to build molecular signatures for tumor stage identification and prognosis. However, it ...
  • Casadevall Aguilar, David; Kilian, Anaïs Yacine; Bellmunt Molins, Joaquim, 1959- (Elsevier, 2017)
    BACKGROUND: Despite adequate treatment and follow-up, around one fifth of patients with localized bladder cancer will present with disease progression. Adequate prognostic biomarkers are lacking to define patients who are ...
  • Claverias, Laura; Marí, Antoni, 1944-; Marin Corral, Judith; Magret, Mónica; Trefler, Sandra; Bodí, María; García-España, Antonio; Yébenes, Juan Carlos; Pascual, Sergi, 1979-; Gea Guiral, Joaquim; Rodríguez, Alejandro (BioMed Central, 2016)
    BACKGROUND: Community-acquired pneumonia (CAP) mortality exceeds 20 % in critical care patients despite appropriate antibiotic therapy. Regional tissue oxygen saturation index (rSO2) measured with near-infrared spectroscopy ...
  • Baumstark, Rebecca; Hänzelmann, Sonja, 1981-; Tsuru, Saburo; Schaerli, Yolanda; Francesconi, Mirko; Mancuso, Francesco M.; Castelo Valdueza, Robert; Isalan, Mark (Nature Publishing Group, 2015)
    What happens to gene expression when you add new links to a gene regulatory network? To answer this question, we profile 85 network rewirings in E. coli. Here we report that concerted patterns of differential expression ...
  • Meyer, Markus; Vilardell, Josep (Oxford University Press, 2009)
    Removal of introns during pre-mRNA splicing is a critical process in gene expression, and understanding its control at both single-gene and genomic levels is one of the great challenges in Biology. Splicing takes place in ...
  • Colell Ortega, Esther, 1961-; Bell, Steven; Britton, Annie (BMJ Publishing Group, 2014)
    BACKGROUND AND AIMS: Studies on the role of labour market position and change in alcohol use during midlife are scarce and their results are inconclusive mainly due to their failure to define comprehensive and distinct ...

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