Benvinguts al Repositori Digital de la UPF

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

Visualitzant Articles (Departament de Ciències Experimentals i de la Salut) per títol

Ordena per: Ordre: Resultats:

  • Hall, Janet; Jeggo, Penny A.; West, Catharine; Gomolka, Maria; Quintens, Roel; Badie, Christophe; Laurent, Olivier; Aerts, Ann; Anastasov, Nataša; Azimzadeh, Omid; Azizova, Tamara; Baatout, Sarah; Baselet, Bjorn; Benotmane, Mohammed A.; Blanchardon, Eric; Guéguen, Yann; Haghdoost, Siamak; Harms-Ringhdahl, Mats; Hess, Julia; Kreuzer, Michaela; Laurier, Dominique; Macaeva, Ellina; Manning, Grain; Pernot, Eileen; Ravanat, Jean-Luc; Sabatier, Laure; Tack, Karine; Tapio, Soile; Zitzelsberger, Horst; Cardis, Elisabeth (Elsevier, 2017)
    Recent epidemiology studies highlighted the detrimental health effects of exposure to low dose and low dose rate ionizing radiation (IR): nuclear industry workers studies have shown increased leukaemia and solid tumour ...
  • Fernandes, Jacqueline; Lorenzo, Ivan M.; Andrade, Yaniré N.; Garcia-Elias Heras, Anna; Serra Pascual, Selma A., 1981-; Fernández-Fernández, José Manuel, 1967-; Valverde, M. A. (Miguel Ángel), 1963- (Rockefeller University Press, 2008)
    Mechanical and osmotic sensitivity of the transient receptor potential vanilloid 4 (TRPV4) channel depends on phospholipase A(2) (PLA(2)) activation and the subsequent production of the arachidonic acid metabolites, ...
  • Middleton, Robert; Gao, Dadi; Thomas, Aubin; Singh, Babita, 1986-; Au, Amy; Wong, Justin J.-L.; Bomane, Alexandra; Cosson, Bertrand; Eyras Jiménez, Eduardo; Rasko, John E.J.; Ritchie, William (BioMed Central, 2017)
    Intron retention (IR) occurs when an intron is transcribed into pre-mRNA and remains in the final mRNA. We have developed a program and database called IRFinder to accurately detect IR from mRNA sequencing data. Analysis ...
  • García Santamarina, Sarela, 1978-; Boronat i Llop, Susanna, 1965-; Calvo, Isabel A.; Rodríguez Gabriel, Miguel; Ayté del Olmo, José; Molina, Henrik; Hidalgo Hernando, Elena (Mary Ann Liebert, Inc, 2013)
    Cysteine oxidation mediates oxidative stress toxicity and signaling. It has been long proposed that the thioredoxin (Trx) system, which consists of Trx and thioredoxin reductase (Trr), is not only involved in recycling ...
  • Fröhlich, Matthias; Pinart, Mariona; Keller, Theresa; Reich, Andreas; Cabieses, Báltica; Hohmann, Cynthia; Postma, Dirkje S.; Bousquet, Jean; Antó i Boqué, Josep Maria; Keil, Thomas; Roll, Stephanie (BioMed Central, 2017)
    BACKGROUND: Allergic rhinitis and asthma as single entities affect more boys than girls in childhood but more females in adulthood. However, it is unclear if this prevalence sex-shift also occurs in allergic rhinitis and ...
  • Soriano Tarraga, Carolina; Giralt-Steinhauer, Eva; Mola Caminal, Marina; Vivanco Hidalgo, Rosa María; Ois Santiago, Angel Javier; Rodríguez‐Campello, Ana; Cuadrado Godia, Elisa; Sayols, Sergi; Elosua Llanos, Roberto; Roquer, Jaume; Jiménez‐Conde, Jordi ( Impact Journals, 2016)
    Ischemic stroke is associated with aging. It is possible to predict chronological age by measuring age-related changes in DNA methylation from multiple CpG sites across the genome, known as biological age. The difference ...
  • Lyle, Robert; Prandini, Paola; Osoegawa, Kazutoyo; Ten Hallers, Boudewijn; Humphray, Sean; Zhu, Baoli; Eyras Jiménez, Eduardo; Castelo Valdueza, Robert; Bird, Christine P.; Gagos, Sarantos; Scott, Carol; Cox, Antony; Deutsch, Samuel; Ucla, Catherine; Cruts, Marc; Dahoun, Sophie; She, Xinwei; Bena, Frederique; Wang, Sheng-Yue; Broeckhoven, Christine van; Eichler, Evan E.; Guigó Serra, Roderic; Rogers, Jane; De Jong, Pieter J.; Reymond, Alexandre; Antonarakis, Stylianos E. (Cold Spring Harbor Laboratory Press-CSHL Press, 2007)
    The goals of the human genome project did not include sequencing of the heterochromatic regions. We describe here an initial sequence of 1.1 Mb of the short arm of human chromosome 21 (HSA21p), estimated to be 10% of 21p. ...
  • Neves, Joana; Parada, Carolina; Chamizo, Mireia; Giráldez, Fernando (Company of Biologists, 2011)
    Hair cells of the inner ear sensory organs originate from progenitor cells located at specific domains of the otic vesicle: the prosensory patches. Notch signalling is necessary for sensory development and loss of function ...
  • Hénaff, Elizabeth; Zapata Ortiz, Luis, 1985-; Casacuberta, Josep M.; Ossowski, Stephan (BioMed Central, 2015)
    Background: Transposable elements are major players in genome evolution. Transposon insertion polymorphisms can/ntranslate into phenotypic differences in plants and animals and are linked to different diseases including ...
  • Bosque Prous, Marina, 1984-; Espelt Hernández, Albert, 1981-; Sordo, Luis; Guitart, Anna (Guitart i Garcia); Brugal i Puig, M. Teresa; Bravo, María José (Public Library of Science (PLoS), 2015)
    BACKGROUND: To estimate the incidence of hazardous drinking in middle-aged people during an economic recession and ascertain whether individual job loss and contextual changes in unemployment influence the incidence rate ...
  • Chow, Alan; Erisir, A.; Farb, C.; Nadal, M. S.; Ozaita Mintegui, Andrés, 1969-; Lau, David; Welker, E.; Rudy, Bernardo (Society for Neuroscience, 1999)
    Kv3.1 and Kv3.2 K+ channel proteins form similar voltage-gated K+ channels with unusual properties, including fast activation at voltages positive to −10 mV and very fast deactivation rates. These properties are thought ...
  • Blanco, Gonzalo; Puiggros Metje, Anna Maria; Rodríguez-Rivera, María; Gimeno Vázquez, Eva; Abella Monreal, Eugenia; Ferrer Del Alamo, Ana; Espinet Solà, Blanca (Impact Journals, 2016)
    Patients with chronic lymphocytic leukemia (CLL) harboring TP53 aberrations (TP53abs; chromosome 17p deletion and/or TP53 mutation) exhibit an unfavorable clinical outcome. Chromosome 8 abnormalities, namely losses of 8p ...
  • Cantero Recasens, Gerard, 1984-; Butnaru, Cristian M.; Valverde, M. A. (Miguel Ángel), 1963-; Naranjo, José R.; Brouwers, Nathalie; Malhotra, Vivek (eLife, 2018)
    Regulated mucin secretion from specialized goblet cells by exogenous agonist-dependent (stimulated) and -independent (baseline) manner is essential for the function of the epithelial lining. Over extended periods, baseline ...
  • Solé, Laura; Roura Ferrer, Meritxell; Pérez Verdaguer, Mireia; Oliveras, Anna; Calvo, Maria; Fernández-Fernández, José Manuel, 1967-; Felipe, Antonio (Company of Biologists, 2009)
    Voltage-dependent potassium channels (Kv) play a crucial role in the activation and proliferation of leukocytes. Kv channels are either homo- or hetero-oligomers. This composition modulates their surface expression and ...
  • Radó i Trilla, Núria, 1985-; Arató, Krisztina, 1981-; Pegueroles Queralt, Maria Cinta; Raya, Alicia; Luna, Susana de la; Albà Soler, Mar (Open University Press, 2015)
    The high regulatory complexity of vertebrates has been related to two rounds of whole genome duplication (2R-WGD) that occurred before the divergence of the major vertebrate groups. Following these events, many developmental ...
  • Wakana, Yuichi; Villeneuve, Julien; Galen, Josse van; Cruz Garcia, David; Tagaya, Mitsuo; Malhotra, Vivek (Rockefeller University Press, 2013)
    Here we report that the kinesin-5 motor Klp61F, which is known for its role in bipolar spindle formation in mitosis, is required for protein transport from the Golgi complex to the cell surface in Drosophila S2 cells. ...
  • Szegezdi, Eva; van der Sloot, Almer M.; Mahalingam, Devalingam; O'Leary, Lynda; Cool, Robbert H.; Muñoz, Inés G.; Montoya, Guillermo; Quax, Wim J.; Jong, Steven M. de, 1962-; Samali, Afshin; Serrano Pubull, Luis, 1982- (American Society for Biochemistry and Molecular Biology (ASBMB), 2012)
    Here we show by computer modeling that kinetics and outcome of signal transduction in case of hetero-oligomerizing receptors of a promiscuous ligand largely depend on the relative amounts of its receptors. Promiscuous ...
  • Cisneros, Elisa; Moraru, Manuela; Gómez-Lozano, Natalia; López-Botet, Miguel; Vilches, Carlos (Frontiers, 2012)
    A recently developed anti-KIR2DL5 (CD158f) antibody has demonstrated KIR2DL5 expression on the surface of NK and T lymphocytes, making it the last functional KIR identified in the human genome. KIR2DL5 belongs to an ancestral ...
  • Sutherland, Jessie M.; Sobinoff, Alexander P.; Gunter, Kara M.; Fraser, Barbara A.; Pye, Victoria; Bernstein, Ilana R.; Boon, Evan; Siddall, Nicole A.; Andrés, Luisa De; Hime, Gary R.; Holt, Janet E.; Graf, T. (Thomas); McLaughlin, Eileen A. (MDPI, 2015)
    Characterizing the mechanisms underlying follicle development in the ovary is crucial to understanding female fertility and is an area of increasing research interest. The RNA binding protein Musashi is essential for ...
  • Maier, Dieter; Kalus, Wenzel; Wolff, Martin; Kalko, Susana G.; Roca Torrent, Josep; Marin de Mas, Igor; Turan, Nil; Cascante, Marta; Falciani, Francesco; Hernández, Miguel; Villà i Freixa, Jordi; Losko, Sascha (BioMed Central, 2011)
    Background: To enhance our understanding of complex biological systems like diseases we need to put all of the available data into context and use this to detect relations, pattern and rules which allow predictive hypotheses ...