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Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

Browsing Articles (Departament de Ciències Experimentals i de la Salut) by Title

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  • Prasad, Aparna; Rabionet, Raquel; Espinet Solà, Blanca; Zapata Ortiz, Luis, 1985-; Puiggros Metje, Anna Maria; Melero Vilella, Maria Carme; Puig, Anna; Sarria-Trujillo, Yaris; Ossowski, Stephan; Garcia-Muret, Maria P.; Estrach, Teresa; Servitje, Octavio; Lopez-Lerma, Ingrid; Gallardo Hernández, Fernando; Pujol Vallverdú, Ramon Maria; Estivill, Xavier, 1955- (Elsevier, 2016)
    Sézary syndrome is a leukemic form of cutaneous T-cell lymphoma with an aggressive clinical course. The genetic etiology of the disease is poorly understood, with chromosomal abnormalities and mutations in some genes being ...
  • Monlong, Jean; Calvo, Miquel; Ferreira, Pedro G.; Guigó Serra, Roderic (Nature Publishing Group, 2014)
    Identification of genetic variants affecting splicing in RNA sequencing population studies is still in its infancy. Splicing phenotype is more complex than gene expression and ought to be treated as a multivariate phenotype ...
  • Martinez, Javier P.; Hinkelmann, Bettina; Fleta Soriano, Eric, 1983-; Steinmetz, Heinrich; Jansen, Rolf; Díez Antón, Juana, 1962-; Frank, Ronald; Sasse, Florenz; Meyerhans, Andreas (BioMed Central, 2013)
    Drug-resistance and therapy failure due to drug-drug interactions are the main challenges in current treatment against Human Immunodeficiency Virus (HIV) infection. As such, there is a continuous need for the development ...
  • Clop, Alex; Sharaf, Abdoallah; Castelló, Anna; Ramos-Onsins, Sebastián; Cirera, Susanna; Mercadé, Anna; Derdak, Sophia; Beltran, Sergi; Huisman, Abe; Fredholm, Merete; van As, Pieter; Sánchez, Armand (BioMed Central, 2016)
    Background: Taste receptors (TASRs) are essential for the body’s recognition of chemical compounds. In the tongue, TASRs sense the sweet and umami and the toxin-related bitter taste thus promoting a particular eating ...
  • Pérez Hernández, Guillermo; Paul, Fabian; Giorgino, Toni; De Fabritiis, Gianni (American Institute of Physics (AIP), 2013)
    A goal in the kinetic characterization of a macromolecular system is the description of its slow relaxation processes via (i) identification of the structural changes involved in these processes and (ii) estimation of the ...
  • Roberto, Giuseppe; Mayer, Miguel Ángel, 1960-; Gini, Rosa (Public Library of Science (PLoS) , 2016)
    Due to the heterogeneity of existing European sources of observational healthcare data, data source-tailored choices are needed to execute multi-data source, multi-national epidemiological studies. This makes transparent ...
  • Harrow, Jennifer; Nagy, Alinda; Reymond, Alexandre; Alioto, Tyler; Patthy, Laszlo; Antonarakis, Stylianos E.; Guigó Serra, Roderic (BioMed Central, 2009)
    The vast majority of the biology of a newly sequenced genome is inferred from the set of encoded proteins. Predicting this set is therefore invariably the first step after the completion of the genome DNA sequence. Here ...
  • Giannoula, Alexia; Gutiérrez Sacristán, Alba; Bravo Serrano, Àlex, 1984-; Sanz, Ferran; Furlong, Laura I., 1971- (Nature Publishing Group, 2018)
    Time is a crucial parameter in the assessment of comorbidities in population-based studies, as it permits to identify more complex disease patterns apart from the pairwise disease associations. So far, it has been, either, ...
  • Senthivel, Vivek Raj, 1983-; Sturrock, Marc; Piedrafita, Gabriel; Isalan, Mark (Nature Publishing Group, 2016)
    Nonlinear responses to signals are widespread natural phenomena that affect various cellular processes. Nonlinearity can be a desirable characteristic for engineering living organisms because it can lead to more switch-like ...
  • Aznar Benitah, Salvador; Lafzi, Atefeh; Berenguer-Llergo, Antonio; Youssif, Catrin; Castellanos, Andrés; Solanas, Guiomar; Peixoto, Francisca Oliveira; Stephan-Otto Attolini, Camille; Prats, Neus; Aguilera, Mònica; Martín Caballero, Juan; Heyn, Holger; Aznar Benitah, Salvador (Elsevier, 2018)
    During aging, stromal functions are thought to be impaired, but little is known whether this stems from changes of fibroblasts. Using population- and single-cell transcriptomics, as well as long-term lineage tracing, we ...
  • Valera, Alexandra; Balagué, Olga; Colomo Saperas, Luis Alberto; Martínez García, Antonio; Delabie, Jan; Taddesse-Heath, Lekidelu; Jaffe, Elaine S.; Campo, Elias (Lippincott Williams & Wilkins, 2010)
    Plasmablastic lymphoma (PBL) is an aggressive lymphoma characterized by a terminally differentiated B-cell phenotype that usually occurs in the immunocompromised or elderly patients. Although the clinical and pathologic ...
  • Vento-Tormo, Roser; Company Nevado, Juan; Rodríguez Ubreva, Javier; de la Rica, Lorenzo; Urquiza, José M.; Javierre, Biola M.; Sabarinathan, Radhakrishnan; Luque, Ana; Esteller, Manel; Aran, Josep M.; Álvarez Errico, Damiana; Ballestar, Esteban (BioMed Central, 2016)
    Background: The role of cytokines in establishing specific transcriptional programmes in innate immune cells has long been recognized. However, little is known about how these extracellular factors instruct innate immune ...
  • Olarte, Omar E.; Licea-Rodriguez, Jacob; Palero, Jonathan A.; Gualda, Emilio J.; Artigas, David; Mayer, Jürgen, 1977-; Swoger, Jim; Sharpe, James; Rocha-Mendoza, Israel; Rangel-Rojo, Raul; Loza-Alvarez, Pablo (Optical Society of America (OSA), 2012)
    We present the implementation of a combined digital scanned light-sheet microscope (DSLM) able to work in the linear and nonlinear regimes under either Gaussian or Bessel beam excitation schemes. A complete characterization ...
  • Sousa, Emily; Agudelo Suárez, Andrés A; Benavides, Fernando G. (Fernando García); Schenker, Marc; García, Ana M.; Benach, Joan; Delclós Gómez-Morán, Carlos Eric; López Jacob, María José; Ruiz Frutos, Carlos; Ronda-Pérez, Elena; Porthé, Victoria; ITSAL project (Springer, 2010)
    OBJECTIVE: To analyze the relationship of legal status and employment conditions with health indicators in foreign-born and Spanish-born workers in Spain. METHODS: Cross-sectional study of 1,849 foreign-born and 509 ...
  • Soria, Ivana; Quattrocchi, Valeria; Langellotti, Cecilia; Pérez-Filgueira, Mariano; Pega, J.; Gnazzo, V.; Romera, S.; Schammas, J.; Bucafusco, D.; Di Giacomo, S.; Torre, Beatriz G. de la; Andreu Martínez, David; Sobrino, Francisco; Blanco, Esther; Zamorano, Patricia (Hindawi, 2018)
    Synthetic peptides mimicking protective B- and T-cell epitopes are good candidates for safer, more effective FMD vaccines. Nevertheless, previous studies of immunization with linear peptides showed that they failed to ...
  • Villalonga, Núria; David, Miren; Bielanska, Joanna; Vicente García, Rubén, 1978-; Comes, Núria; Valenzuela, Carmen; Felipe, Antonio (Rockefeller University Press, 2010)
    Voltage-dependent potassium (K(v)) channels play a pivotal role in the modulation of macrophage physiology. Macrophages are professional antigen-presenting cells and produce inflammatory and immunoactive substances that ...
  • Hernández, Gimena; Dima, Alexandra L.; Pont Acuña, Àngels; Garin Boronat, Olatz, 1979-; Martí-Pastor, Marc; Alonso Caballero, Jordi; Van Ganse, Eric; Laforest, Laurent; Bruin, Marijn de; Mayoral, Karina; Ferrer Forés, Maria Montserrat; ASTRO-LAB group (Public Library of Science (PLoS), 2018)
    Background: The aim was to evaluate the impact of asthma on patients’ Health-Related Quality of Life (HRQoL) by comparing asthmatic women and men with reference norms, to examine the factors which contributed to an impaired ...
  • Sorli Redó, M. Luisa; Luque Pardos, Sònia; Segura, Concepción; Campillo Ambrós, Núria; Montero , Maria Milagro; Esteve, Erika; Herrera, Sabina; Benito, Natividad; Álvarez Lerma, Francisco; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo (BioMed Central, 2017)
    Background: Colistin has a narrow therapeutic window with nephrotoxicity being the major dose-limiting adverse effect. Currently, the optimal doses and therapeutic plasma levels are unknown. Methods: Prospective observational ...
  • Álvarez Pedrerol, Mar; Rivas, Ioar; López Vicente, Mònica, 1988-; Suades González, Elisabet; Donaire González, David; Cirach, Marta; de Castro, Montserrat; Esnaola, Mikel; Basagaña Flores, Xavier; Dadvand, Payam; Nieuwenhuijsen, Mark J.; Sunyer Deu, Jordi (Elsevier, 2017)
    A few studies have found associations between the exposure to traffic-related air pollution at school and/or home and cognitive development. The impact on cognitive development of the exposure to air pollutants during ...
  • Funtikova, Anna N.; Navarro, Estanislau; Bawaked, Rowaedh Ahmed; Fitó Colomer, Montserrat; Schröder, Helmut, 1958- (BioMed Central, 2015)
    The manifestation of cardiovascular risk factors, such as hypertension, diabetes, and particularly obesity begins in children and adolescents, with deleterious effects for cardiometabolic health at adulthood. Although the ...

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