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Articles (Departament de Ciències Experimentals i de la Salut)

Articles (Departament de Ciències Experimentals i de la Salut)

 

Articles de recerca, en accés obert, del Departament de Ciències Experimentals i de la Salut de la UPF.

Recent Submissions

  • Reese, Sarah E.; Ruiz Arenas, Carlos, 1990-; Antó i Boqué, Josep Maria; London, Stephanie J. (Elsevier, 2019)
    Epigenetic mechanisms, including methylation, can contribute to childhood asthma. Identifying DNA methylation profiles in asthmatic patients can inform disease pathogenesis. OBJECTIVE: We sought to identify differential ...
  • Ferránzez Quirante, Olivia; Casañ, Borja; Grau Cerrato, Santiago; Louro, Javier; Salas Sanchez, Esther; Castells, Xavier; Sala Serra, Maria (Elsevier, 2019)
    OBJECTIVE: To describe drug-related problems identified in hospitalized patients and to assess physicians' acceptance rate of pharmacists' recommendations. METHODS: Retrospective observational study that included all ...
  • Roewenstrunk, Julia Maria, 1981-; Di Vona, Chiara, 1981-; Chen, Jie; Borràs, Eva; Dong, Chao; Arató, Krisztina, 1981-; Sabidó Aguadé, Eduard, 1981-; Huen, Michael S. Y.; Luna Gargantilla, Susana de la (Nature Research, 2019)
    Dysregulation of the DYRK1A protein kinase has been associated with human disease. On the one hand, its overexpression in trisomy 21 has been linked to certain pathological traits of Down syndrome, while on the other, ...
  • Horvath, Attila; Daniel, Bence; Szeles, Lajos; Cuaranta-Monroy, Ixchelt; Czimmerer, Zsolt; Ozgyin, Lilla; Steiner, Laszlo; Kiss, Mate; Simandi, Zoltan; Poliska, Szilard; Giannakis, Nikolas; Raineri, Emanuele; Gut, Ivo Glynne; Nagy, Benedek; Nagy, Laszlo (Oxford University Press, 2019)
    The concept of tissue-specific gene expression posits that lineage-determining transcription factors (LDTFs) determine the open chromatin profile of a cell via collaborative binding, providing molecular beacons to ...
  • Spill, Yannick G.; Castillo Andreo, David; Vidal, Enrique; Marti-Renom, Marc A. (Nature Research, 2019)
    Chromosome conformation capture techniques, such as Hi-C, are fundamental in characterizing genome organization. These methods have revealed several genomic features, such as chromatin loops, whose disruption can have ...
  • Sanchez de Groot, Natalia; Torrent, Marc; Ravarani, Charles N.J.; Trusina, Ala; Ventura, Salvador; Babu, M. Madan (Wiley-VCH Verlag, 2019)
    Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane-less compartments for many cellular processes. What are the fitness ...
  • Zacco, Elsa; Graña-Montes, Ricardo; Martin, Stephen R.; Sanchez de Groot, Natalia; Alfano, Caterina; Tartaglia, Gian Gaetano; Pastore, Annalisa (Elsevier, 2019)
    Amyotrophic lateral sclerosis and frontotemporal lobar degeneration are incurable motor neuron diseases associated with muscle weakness, paralysis and respiratory failure. Accumulation of TAR DNA-binding protein 43 (TDP-43) ...
  • Stervbo, Ulrik; Nienen, Mikalai; Weist, Benjamin J. D.; Kuchenbecker, Leon; Hecht, Jochen; Wehler, Patrizia; Westhoff, Timm H.; Reinke, Petra; Babel, Nina (Frontiers Media, 2019)
    Reactivation of the BK polyomavirus is known to lead to severe complications in kidney transplant patients. The current treatment strategy relies on decreasing the immunosuppression to allow the immune system to clear the ...
  • Mixão, Verónica; Perez Hansen, Antonio; Saus Martínez, Ester; Boekhout, Teun; Lass-Florl, Cornelia; Gabaldón Estevan, Juan Antonio, 1973- (Frontiers Media, 2019)
    Fungal infections such as those caused by Candida species are increasingly common complications in immunocompromised patients. The list of causative agents of candidiasis is growing and comprises a set of emerging species ...
  • Janssens, Georges E.; Lin, Xin-Xuan; Millán Ariño, Lluís, 1984-; Kavšek, Alan; Sen, Ilke; Seinstra, Renée I.; Stroustrup, Nicholas; Nollen, Ellen A. A.; Riedel, Christian G. (Elsevier, 2019)
    Aging strongly influences human morbidity and mortality. Thus, aging-preventive compounds could greatly improve our health and lifespan. Here we screened for such compounds, known as geroprotectors, employing the power of ...
  • Mocavini, Ivano; Pippa, Simone; Licursi, Valerio; Paci, Paola; Trisciuoglio, Daniela; Mannironi, Cecilia; Presutti, Carlo; Negri, Rodolfo (Wiley Open Access, 2019)
    JARID1B/KDM5B histone demethylase's mRNA is markedly overexpressed in breast cancer tissues and cell lines and the protein has been shown to have a prominent role in cancer cell proliferation and DNA repair. However, the ...
  • Martínez Corral, Rosa; Liu, Jintao; Süel, Gürol M.; García Ojalvo, Jordi (National Academy of Sciences, 2018)
    Biofilm communities of Bacillus subtilis bacteria have recently been shown to exhibit collective growth-rate oscillations mediated by electrochemical signaling to cope with nutrient starvation. These oscillations emerge ...
  • Vrotsou, Kalliopi; Ávila Pacheco, Mónica Marcela, 1984-; Machón, Mónica; Mateo-Abad, Maider; Pardo Cladellas, Yolanda; Garin Boronat, Olatz, 1979-; Zaror, Carlos; González, Nerea; Escobar, Antonio; Cuéllar, Ricardo (SpringerOpen, 2018)
    PURPOSE: The objective of this study was to evaluate the psychometric properties of the Constant-Murley Score (CMS) in various shoulder pathologies, based on a systematic review and expert standardized evaluations. METHODS: ...
  • Hernandez, Gimena; Garin Boronat, Olatz, 1979-; Pardo, Yolanda; Vilagut Saiz, Gemma, 1975-; Pont Acuña, Àngels; Suárez, Mónica; Neira, Montse; Rajmil Rajmil, Luis Alberto; Gorostiza, Inigo; Ramallo-Fariña, Yolanda; Cabases, Juan; Alonso Caballero, Jordi; Ferrer Forés, Maria Montserrat (Springer, 2018)
    BACKGROUND AND OBJECTIVE: The EuroQol 5 dimensions 5 levels (EQ-5D-5L) is the new version of EQ-5D, developed to improve its discriminatory capacity. This study aims to evaluate the construct validity of the Spanish version ...
  • Forero, Carlos G.; Olariu, Elena, 1984-; Álvarez López, Pilar; Castro-Rodriguez, José-Ignacio; Blasco Cubedo, Maria Jesus; Vilagut Saiz, Gemma, 1975-; Alonso Caballero, Jordi; INSAyD Investigators (Springer, 2018)
    PURPOSE: Functioning is a necessary diagnostic criterion for depression, and thus routinely assessed in depressive patients. While it is highly informative of disorder severity, its change has not been tested for prognostic ...
  • García Ojalvo, Jordi (Nature Research, 2019)
    A large-scale imaging study has tracked thousands of bacteria living in three-dimensional biofilms. This technical tour de force reveals the importance of mechanical interactions between cells for building local and global ...
  • Lee, Dong-yeon D.; Galera Laporta, Letícia, 1985-; Bialecka-Fornal, Maja; Moon, Eun Chae; Shen, Zhouxin; Briggs, Steven P.; García Ojalvo, Jordi; Süel, Gürol M. (Elsevier, 2019)
    Bacteria exhibit cell-to-cell variability in their resilience to stress, for example, following antibiotic exposure. Higher resilience is typically ascribed to "dormant" non-growing cellular states. Here, by measuring ...
  • Dalmases Massegú, Alba, 1982-; González González, Irene; Menendez Romero, Silvia; Arpí Llucià, Oriol; Corominas Torres, Josep Maria; Servitja Tormo, Sonia; Tusquets, Ignasi; Chamizo, Cristina; Rincón, Raúl; Espinosa Blay, Lluís; Bigas Salvans, Anna; Eroles, Pilar; Furriol, Jessica; Lluch, Ana; Rovira Guerín, Ana; Albanell Mestres, Joan; Rojo, Federico (Impact Journals, 2014)
    NF-кB has been linked to doxorubicin resistance in breast cancer patients. NF-кB nuclear translocation and DNA binding in doxorubicin treated-breast cancer cells have been extensively examined; however its functional ...
  • Nieuwenhuijsen, Mark J.; Martinez Murciano, David; Grellier, James; Bennett, James; Best, Nicky; Iszatt, Nina; Vrijheid, Martine; Toledano, Mireille B. (National Institute of Environmental Health Sciences (NIEHS), 2009)
    OBJECTIVES: The aim of this study was to review epidemiologic evidence, provide summary risk estimates of the association between exposure to chlorination disinfection by-products (DBPs) and congenital anomalies, and provide ...
  • Vrijheid, Martine; Martinez Murciano, David; Manzanares, Sandra; Dadvand, Payam; Schembari, Anna, 1982-; Rankin, Judith; Nieuwenhuijsen, Mark J. (National Institute of Environmental Health Sciences (NIEHS), 2011)
    OBJECTIVE: We systematically reviewed epidemiologic studies on ambient air pollution and congenital anomalies and conducted meta-analyses for a number of air pollutant-anomaly combinations. DATA SOURCES AND EXTRACTION: ...

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