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Articles (Departament de Ciències Experimentals i de la Salut)

Articles (Departament de Ciències Experimentals i de la Salut)

 

Articles de recerca, en accés obert, del Departament de Ciències Experimentals i de la Salut de la UPF.

Enviaments recents

  • Sayols, Sergi; Subirana Cachinero, Isaac; Lluís Ganella, Carla, 1984-; Civeira, F.; Roquer, Jaume; Do, AN; Absher, D.; Cenarro, A.; Muñoz, D.; Soriano Tarraga, Carolina; Jiménez Conde, Jordi; Ordovás, José M.; Sentí Clapés, Mariano; Aslibekyan, Stella; Marrugat de la Iglesia, Jaume; Arnett, D.K.; Elosua Llanos, Roberto (Oxford University Press, 2016)
    Lipid traits (total, low-densityand high-density lipoproteincholesterol, and triglycerides) are risk factors for cardiovascular disease. DNA methylation is an inherited but also modifiable epigenetic mark ...
  • Domínguez-Álvarez, Marisol; Gea Guiral, Joaquim; Barreiro Portela, Esther (Wiley, 2017)
    We hypothesized that inflammatory events and reactive oxygen species (ROS) production may be differentially expressed in respiratory and limb muscles, and blood of a chronic intermittent hypoxia (CIH) experimental model ...
  • Mateu Jiménez, Mercè; Curull Serrano, Víctor; Pijuan Andujar, Lara; Sánchez-Font, Albert; Rivera-Ramos, Hugo; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Gea Guiral, Joaquim; Barreiro Portela, Esther (Elsevier, 2017)
    INTRODUCTION: Chronic respiratory conditions, especially chronic obstructive pulmonary disease (COPD), and inflammatory events underlie lung cancer (LC). We hypothesized that profiles of T helper 1 and T helper 2 cytokines ...
  • Ballantyne, Kaye N.; Comas, David, 1969-; Sanz, Paula; Kayser, Manfred (Wiley, 2014)
    Relevant for various areas of human genetics, Y-chromosomal short tandem repeats (Y-STRs) are commonly used for testing close paternal relationships among individuals and populations, and for male lineage identification. ...
  • Alves, Joao M.; Lima, Ana C.; Pais, Isa A.; Amir, Nadir; Celestino, Ricardo; Piras, Giovanna; Monne, Maria; Comas, David, 1969-; Heutink, Peter; Chikhi, Lounès; Amorim, António; Lopes, Alexandra M. (Oxford University Press, 2015)
    A polymorphic inversion that lies on chromosome 17q21 comprises two major haplotype families (H1 and H2) that not only differ in orientation but also in copy-number. Although the processes driving the spread of the ...
  • Sandoval, José R.; Lacerda, Daniela R.; Acosta, Oscar; Jota, Marilza S.; Robles Ruiz, Paulo; Salazar-Granara, Alberto; Vieira, Pedro Paulo R.; Paz-y-Miño, César; Fujita, Ricardo; Santos, Fabricio R.; Bertranpetit, Jaume, 1952-; Comas, David, 1969-; Genographic Project Consortium (Wiley, 2016)
    This study focuses on the genetic history of the Quechua-Lamistas, inhabitants of the Lamas Province in the San Martin Department, Peru, who speak their own distinct variety of the Quechua family of languages. It has been ...
  • Sunyer Deu, Jordi; Suades González, Elisabet; García Esteban, Raquel; Rivas, Ioar; Pujol, Jesús; Álvarez Pedrerol, Mar; Forns i Guzman, Joan, 1981-; Querol, Xavier; Basagaña Flores, Xavier (Wolters Kluwer Health, 2017)
    BACKGROUND: Although air pollution's short-term effects are well understood to be marked and preventable, its acute neuropsychological effects have, to our knowledge, not yet been studied. We aim to examine the association ...
  • Blanco, Gonzalo; Puiggros Metje, Anna Maria; Rodríguez-Rivera, María; Gimeno Vázquez, Eva; Abella Monreal, Eugenia; Ferrer Del Alamo, Ana; Espinet, Blanca (Impact Journals, 2016)
    Patients with chronic lymphocytic leukemia (CLL) harboring TP53 aberrations (TP53abs; chromosome 17p deletion and/or TP53 mutation) exhibit an unfavorable clinical outcome. Chromosome 8 abnormalities, namely losses of 8p ...
  • Hernández-Muñoz, Inmaculada; Figuerola, Elisabeth; Sanchez-Molina, Sara; Rodriguez, Eva; Fernández Mariño, Ana Isabel, 1984-; Pardo-Pastor, Carlos; Bahamonde Santos, María Isabel; Fernández-Fernández, José Manuel, 1967-; García-Domínguez, Daniel J.; Hontecillas-Prieto, Lourdes; Lavarino, Cinzia; Carcaboso, Angel M.; Torres, Carmen de; Tirado, Oscar M.; Alava, Enrique de; Mora, Jaume (Impact Journals, 2016)
    Ewing sarcoma (ES) is an aggressive tumor defined by EWSR1 gene fusions that behave as an oncogene. Here we demonstrate that RING1B is highly expressed in primary ES tumors, and its expression is independent of the fusion ...
  • Joubert, Bonnie R.; Salas Díaz, Lucas Andrés, 1980-; Ruiz, Carlos; Bustamante Pineda, Mariona; Gonzalez, Juan Ramon; Pinart, Mariona; Guerra, Stefano; Vrijheid, Martine; Antó i Boqué, Josep Maria; Sunyer Deu, Jordi; London, Stephanie J. (Elsevier, 2016)
    Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in pregnancy remains an important public health problem that impacts child ...
  • Koutsoudakis, George; Romero-Brey, Inés; Berger, Carola; Pérez Vilaró, Gemma, 1985-; Monteiro Perin, Paula; Vondran, Florian Wolfgang Rudolf; Kalesse, Markus; Harmrolfs, Kirsten; Müller, Rolf; Martínez, Javier P.; Pietschmann, Thomas; Bartenschlager; Ralf; Brönstrup, Mark; Meyerhans, Andreas; Díez Antón, Juana, 1962- (Elsevier, 2015)
    BACKGROUND & AIMS: Soraphen A (SorA) is a myxobacterial metabolite that inhibits the acetyl-CoA carboxylase, a key enzyme in lipid biosynthesis. We have previously identified SorA to efficiently inhibit the human ...
  • Elsebai, Mahmoud Fahmi; Koutsoudakis, George; Saludes, Verónica; Pérez Vilaró, Gemma, 1985-; Turpeinen, Ari; Mattila, Sampo; Pirttilä, Anna Maria; Fontaine, Fabien; Mehiri, Mohamed; Meyerhans, Andreas; Díez Antón, Juana, 1962- (American Society for Microbiology, 2016)
    Hepatitis C virus (HCV) infection is the leading cause of chronic liver diseases. Water extracts of the leaves of the wild Egyptian artichoke (WEA) [Cynara cardunculus L. var. sylvestris (Lam.) Fiori] have been used for ...
  • Pérez Vilaró, Gemma, 1985-; Fernández-Carrillo, Carlos; Mensa, Laura; Miquel, Rosa; Sanjuan, Xavier; Forns, Xavier; Pérez del Pulgar, Sofía; Díez Antón, Juana, 1962- (Elsevier, 2015)
    BACKGROUND & AIMS: Decoding the myriad of interactions that hepatitis C virus (HCV) establishes with infected cells is mandatory to obtain a complete understanding of HCV biology and its associated pathogenesis. We and ...
  • Jungfleisch, Jennifer, 1986-; Blasco Moreno, Bernat, 1986-; Díez Antón, Juana, 1962- (MDPI, 2016)
    Positive-strand RNA viruses have evolved multiple strategies to not only circumvent the hostile decay machinery but to trick it into being a priceless collaborator supporting viral RNA translation and replication. In this ...
  • Jungfleisch, Jennifer, 1986-; Nedialkova, Danny D.; Dotu, Ivan; Sloan, Katherine E.; Martínez Bosch, Neus; Brüning, Lukas; Raineri, Emanuele; Navarro Medrano, Pilar; Bohnsack, Markus T.; Leidel, Sebastian; Díez Antón, Juana, 1962- (Cold Spring Harbor Laboratory Press (CSHL Press), 2017)
    The impact of RNA structures in coding sequences (CDS) within mRNAs is poorly understood. Here, we identify a novel and highly conserved mechanism of translational control involving RNA structures within coding sequences ...
  • Iorio, Francesco Iorio; Tamborero Noguera, David; López Bigas, Núria; Esteller, Manel; Garnett, Mathew J. (Elsevier, 2016)
    Systematic studies of cancer genomes have provided unprecedented insights into the molecular nature of cancer. Using this information to guide the development and application of therapies in the clinic is challenging. Here, ...
  • Bousquet, Jean; Antó i Boqué, Josep Maria; Mercier, J. (BioMedCentral, 2016)
    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases ...
  • Martinez, Xavier; Pozuelo, Marta; Pascal, Victoria; Campos, David; Gut, Ivo Glynne; Gut, Marta; Azpiroz, Fernando; Guarner, Francisco; Manichanh, Chaysavanh (Nature Publishing Group, 2016)
    To date, meta-omic approaches use high-throughput sequencing technologies, which produce a huge amount of data, thus challenging modern computers. Here we present MetaTrans, an efficient open-source pipeline to analyze the ...
  • Lobanov, Michail Yu.; Klus,Petr, 1985-; Sokolovsky, Igor V.; Tartaglia, Gian Gaetano; Galzitskaya, Oxana V. (Nature Publishing Group, 2016)
    The biological function of multiple repetitions of single amino acids, or homo-repeats, is largely unknown, but their occurrence in proteins has been associated with more than 20 hereditary diseases. Analysing 122 bacterial ...
  • Ferreira, Pedro G.; Oti, Martin; Barann, Matthias; Wieland, Thomas; Ezquina, Suzana; Friedländer, Marc R.; Rivas, Manuel A.; Esteve-Codina, Anna; The GEUVADIS Consortium; Rosenstiel, Philip; Strom, Tim M.; Lappalainen, Tuuli; Guigó Serra, Roderic; Sammeth, Michael (Nature Publishing Group, 2016)
    Recent advances in the cost-efficiency of sequencing technologies enabled the combined DNA- and RNA-sequencing of human individuals at the population-scale, making genome-wide investigations of the inter-individual genetic ...

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