• The inter-annual variability of heat-related mortality in nine European cities (1990-2010)

  Scortichini, Matteo; de'Donato, Francesca; de Sario, Manuela; Leone, Michela; Åström, Christofer; Ballester, Ferran; Basagaña Flores, Xavier; Bobvos, Janos; Gasparrini, Antoni; Katsouyanni, Klea; Lanki, Timo; Menne, Bettina; Pascal, Mathilde; Michelozzi, Paola (BioMed Central, 2018)

  Background: The association between heat and daily mortality and its temporal variation are well known. However, few studies have analyzed the inter-annual variations in both the risk estimates and impacts of heat. The aim ...
• Prenatal and childhood traffic-related air pollution exposure and telomere length in european children: The HELIX Project

  Clemente Batalha Pardal, Diana, 1990-; Vrijheid, Martine; Martens, Dries S.; Bustamante Pineda, Mariona; Chatzi, Leda; Danileviciute, Asta; de Castro, Montserrat; Grazuleviciene, Regina; Gutzkow, Kristine B.; Lepeule, Johanna; Maitre, Léa; McEachan, Rosemary R.C.; Robinson, Oliver; Schwarze, Per E.; Tamayo-Uria, Ibon; Vafeiadi, Marina, 1983-; Wright, John; Slama, Rémy; Nieuwenhuijsen, Mark J.; Nawrot, Tim S. (National Institute of Environmental Health Sciences, 2019)

  Background: Telomere length is a molecular marker of biological aging. Objective: Here we investigated whether early-life exposure to residential air pollution was associated with leukocyte telomere length (LTL) at 8 y of ...
• Influence of the urban exposome on birth weight

  Nieuwenhuijsen, Mark J.; Basagaña Flores, Xavier; Urquiza, José M.; Maitre, Léa; de Castro, Montserrat; Valentín, Antònia; Donaire González, David; Dadvand, Payam; Vrijheid, Martine; Slama, Rémy (National Institute of Environmental Health Sciences, 2019)

  Background: The exposome is defined as the totality of environmental exposures from conception onwards. It calls for providing a holistic view of environmental exposures and their effects on human health by evaluating ...
• Ventilator-induced diaphragm dysfunction: translational mechanisms lead to therapeutical alternatives in the critically ill

  Peñuelas, Oscar; Keough, Elena; López-Rodríguez, Lucía; Carriedo, Demetrio; Gonçalves, Gesly; Barreiro Portela, Esther; Lorente, José Ángel (Elsevier, 2019)

  Mechanical ventilation [MV] is a life-saving technique delivered to critically ill patients incapable of adequately ventilating and/or oxygenating due to respiratory or other disease processes. This necessarily invasive ...
• Diet as a source of exposure to environmental contaminants for pregnant women and children from six european countries

  Papadopoulou, Eleni, 1985-; Haug, Line Småstuen; Sakhi, Amrit Kaur; Andrušaitytė, Sandra; Basagaña Flores, Xavier; Brantsaeter, Anne Lise; Casas Sanahuja, Maribel; Fernández Barres, Silvia; Grazuleviciene, Regina; Knutsen, Helle Katrine; Maitre, Léa; Meltzer, Helle Margrete; McEachan, Rosemary R.C.; Roumeliotaki, Theano; Slama, Rémy; Vafeiadi, Marina, 1983-; Wright, John; Vrijheid, Martine; Thomsen, Cathrine; Chatzi, Leda (National Institute of Environmental Health Sciences, 2019)

  Background: Pregnant women and children are especially vulnerable to exposures to food contaminants, and a balanced diet during these periods is critical for optimal nutritional status. Objectives: Our objective was to ...
• Correlates of walking for travel in seven european cities: The PASTA Project

  Gascon Merlos, Mireia, 1984-; Götschi, Thomas; De Nazelle, Audrey; Gracia Lavedan, Esther; Ambros, Albert; Márquez, Sandra; Marquet, Oriol; Avila Palencia, Ione; Brand, Christian; Iacorossi, Francesco; Raser, Elisabeth; Gaupp-Berghausen, Mailin; Dons, Evi; Laeremans, Michelle; Kahlmeier, Sonja; Sánchez, Julian; Gerike, Regine; Anaya, Esther; Int Panis, Luc; Nieuwenhuijsen, Mark J. (National Institute of Environmental Health Sciences, 2019)

  Background: Although walking for travel can help in reaching the daily recommended levels of physical activity, we know relatively little about the correlates of walking for travel in the European context. Objective: Within ...
• Momentary mood response to natural outdoor environments in four European cities

  Kondo, Michelle C.; Triguero Mas, Margarita, 1985-; Donaire González, David; Seto, Edmund; Valentín, Antònia; Hurst, Gemma; Carrasco Turigas, Glòria; Masterson, Daniel; Ambros, Albert; Ellis, Naomi; Swart, Wim; Davis, Nora; Maas, Jolanda; Jerrett, Michael; Gidlow, Christopher J.; Nieuwenhuijsen, Mark J. (Elsevier, 2020)

  Exposure to natural outdoor environments (NOE) has been shown in population-level studies to reduce anxiety and psychological distress. This study investigated how exposure to one's everyday natural outdoor environments ...
• Exploring mechanisms underlying the relationship between the natural outdoor environment and health and well-being - Results from the PHENOTYPE project

  Kruize, Hanneke; van Kamp, Irene; Berg, Magdalena van den; Kempen, Elise van; Wendel-Vos, Wanda; Ruijsbroek, Annemarie; Swart, Wim; Maas, Jolanda; Gidlow, Christopher J.; Smith, Graham; Ellis, Naomi; Hurst, Gemma; Masterson, Daniel; Triguero Mas, Margarita, 1985-; Cirach, Marta; Gražulevičiene, Regina; Hazel, Peter van den; Nieuwenhuijsen, Mark J. (Elsevier, 2020)

  Background: Despite the large number of studies on beneficial effects of the natural outdoor environment (NOE) on health, the underlying mechanisms are not fully understood. Objective: This study explored the relations ...
• Structural differences in the diaphragm of patients following controlled vs assisted and spontaneous mechanical ventilation

  Marin Corral, Judith; Dot Jordana, Irene; Boguña, M.; Cecchini Rosell, Lluís; Zapatero, Ana; Gracia Arnillas, María Pilar; Pascual Guàrdia, Sergi, 1979-; Vilà Vilardell, Clara; Castellví, A.; Pérez-Terán, Purificación; Gea Guiral, Joaquim; Masclans Enviz, Joan Ramon (Springer, 2019)

  Purpose: Ventilator-induced diaphragm dysfunction or damage (VIDD) is highly prevalent in patients under mechanical ventilation (MV), but its analysis is limited by the difficulty of obtaining histological samples. In this ...
• Changing the urban design of cities for health: The superblock model

  Mueller, Natalie, 1988-; Rojas Rueda, David, 1979-; Khreis, Haneen; Cirach, Marta; Andrés, David; Ballester, Joan; Bartoll, Xavier; Daher, Carolyn; Deluca, Anna; Echave, Cynthia; Milà, Carles; Márquez, Sandra; Palou, Joan; Pérez, Katherine; Tonne, Cathryn; Stevenson, Mark; Rueda, Salvador; Nieuwenhuijsen, Mark J. (Elsevier, 2020)

  Background: Car-dependent city planning has resulted in high levels of environmental pollution, sedentary lifestyles and increased vulnerability to the effects of climate change. The Barcelona Superblock model is an ...
• Traffic related air pollution and the burden of childhood asthma in the contiguous United States in 2000 and 2010

  Alotaibi, Raed; Bechle, Mathew; Marshall, Julian D.; Ramani, Tara; Zietsman, Josias; Nieuwenhuijsen, Mark J.; Khreis, Haneen (Elsevier, 2019)

  Background: Asthma is one of the leading chronic airway diseases among children in the United States (US). Emerging evidence indicates that Traffic Related Air Pollution (TRAP), as opposed to ambient air pollution, leads ...
• The early-life exposome: Description and patterns in six European countries

  Tamayo-Uria, Ibon; Maitre, Léa; Nieuwenhuijsen, Mark J.; Casas Sanahuja, Maribel; de Castro, Montserrat; Robinson, Oliver; Urquiza, José M.; Warembourg, Charline; Vrijheid, Martine; Basagaña Flores, Xavier (Elsevier, 2019)

  Characterization of the "exposome", the set of all environmental factors that one is exposed to from conception onwards, has been advocated to better understand the role of environmental factors on chronic diseases. Here, ...
• Short-term exposure to traffic-related air pollution reveals a compound-specific circulating miRNA profile indicating multiple disease risks

  Krauskopf, Julian; van Veldhoven, Karin; Chadeau-Hyam, Marc; Vermeulen, Roel; Carrasco Turigas, Glòria; Nieuwenhuijsen, Mark J.; Vineis, Paolo; Kok, Theo M. de; Kleinjans, Jos C. (Elsevier, 2019)

  Traffic-related air pollution (TRAP) is a complex mixture of compounds that contributes to the pathogenesis of many diseases including several types of cancer, pulmonary, cardiovascular and neurodegenerative diseases, and ...
• Prenatal exposure to organochlorine compounds and lung function during childhood

  Abellan, Alicia; Sunyer Deu, Jordi; García Esteban, Raquel; Basterrechea, Mikel; Duarte Salles, Talita, 1985-; Ferrero, Amparo; García Aymerich, Judith; Gascon Merlos, Mireia, 1984-; Grimalt Obrador, Joan; Lopez-Espinosa, Maria-José; Zabaleta, Carlos; Vrijheid, Martine; Casas Sanahuja, Maribel (Elsevier, 2019)

  Introduction: Prenatal exposure to organochlorine compounds (OCs) can increase the risk of reported respiratory symptoms in children. It remains unclear whether these compounds can also impact on lung function. We assessed ...
• Maternal swimming pool exposure during pregnancy in relation to birth outcomes and cord blood DNA methylation among private well users

  Salas Díaz, Lucas Andrés, 1980-; Baker, Emily R.; Nieuwenhuijsen, Mark J.; Marsit, Carmen J.; Christensen, Brock C.; Karagas, Margaret R. (Elsevier, 2019)

  Swimming in pools during pregnancy may expose the fetus to water disinfection by-products (DBP). As yet, our understanding of the impacts on DBPs on the fetus is uncertain. Individuals with public water systems are typically ...
• First-trimester maternal concentrations of polyfluoroalkyl substances and fetal growth throughout pregnancy

  Costa, Olga; Iñiguez, Carmen; Manzano Salgado, Cyntia Beatriz, 1987-; Amiano, Pilar; Murcia, Mario; Casas Sanahuja, Maribel; Irizar, Amaia; Basterrechea, Mikel; Beneito, Andrea; Schettgen, Thomas; Sunyer Deu, Jordi; Vrijheid, Martine; Ballester Díez, Ferran; Lopez-Espinosa, Maria-José (Elsevier, 2019)

  Background: Several studies have investigated the possible association between prenatal exposure to perfluoroalkyl substances (PFASs) and birth anthropometry. However, none has assessed fetal size longitudinally. We studied ...
• ExpoApp: an integrated system to assess multiple personal environmental exposures

  Donaire González, David; Valentín, Antònia; van Nunen, Erik; Curto Tirado, Ariadna, 1987-; Rodriguez, Albert; Fernandez-Nieto, Mario; Naccarati, Alessio; Tarallo, Sonia; Tsai, Ming-Yi; Probst-Hensch, Nicole; Vermeulen, Roel; Hoek, Gerard; Vineis, Paolo; Gulliver, John; Nieuwenhuijsen, Mark J. (Elsevier, 2019)

  To assess environmental exposures at the individual level, new assessment methods and tools are required. We developed an exposure assessment system (ExpoApp) for smartphones. ExpoApp integrates: (i) geo-location and ...
• Environmental, health, wellbeing, social and equity effects of urban green space interventions: a meta-narrative evidence synthesis

  Hunter, R.F.; Cleland, C.; Cleary, A.; Droomers, Mariël; Wheeler, B.W.; Sinnett, D.; Nieuwenhuijsen, Mark J.; Braubach, M. (Elsevier, 2019)

  Background: As populations become increasingly urbanised, the preservation of urban green space (UGS) becomes paramount. UGS is not just dedicated recreational space such as public parks, but other types of informal green ...
• Associations of green space metrics with health and behavior outcomes at different buffer sizes and remote sensing sensor resolutions

  Su, Jason; Dadvand, Payam; Nieuwenhuijsen, Mark J.; Bartoll, Xavier; Jerrett, Michael (Elsevier, 2019)

  Satellite data is increasingly used to characterize green space for health outcome studies. Literature suggests that green space within 500 m of home is often used to represent neighborhood suitable for walking, air pollution ...
• Ambient air pollution and overweight and obesity in school-aged children in Barcelona, Spain

  de Bont, Jeroen; Casas Sanahuja, Maribel; Barrera Gómez, Jose; Cirach, Marta; Rivas, Ioar; Valvi, Damaskini, 1983-; Álvarez Pedrerol, Mar; Dadvand, Payam; Sunyer Deu, Jordi; Vrijheid, Martine (Elsevier, 2019)

  Background: Ambient air pollution may increase the risk of overweight and obesity in children. However, available evidence is still scarce and has mainly focused on ambient air pollution exposure occurring at home without ...

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