• Systemic profiles of microRNAs, redox balance, and inflammation in lung

  Qin, Liyun; Guitart, Maria; Curull Serrano, Víctor; Sánchez-Font, Albert; Duran, Xavier; Tang, Jun; Admetlló Papiol, Mireia; Barreiro Portela, Esther (MDPI, 2021)

  Lung cancer (LC) risk increases in patients with chronic respiratory diseases (COPD). MicroRNAs and redox imbalance are involved in lung tumorigenesis in COPD patients. Whether systemic alterations of those events may also ...
• Air pollution, residential greenness and metabolic dysfunction during early pregnancy in the INfancia y Medio Ambiente (INMA) Cohort

  Rammah, Amal; Whitworth, Kristina W.; Amos, Christopher I.; Estarlich, Marisa; Guxens Junyent, Mònica; Ibarluzea, Jesús; Iñiguez, Carmen; Subiza-Pérez, Mikel; Vrijheid, Martine; Symanski, Elaine (MDPI, 2021)

  Despite extensive study, the role of air pollution in gestational diabetes remains unclear, and there is limited evidence of the beneficial impact of residential greenness on metabolic dysfunction during pregnancy. We used ...
• A transdisciplinary approach to recovering natural and cultural landscape and place identification: A case study of Can Moritz spring (Rubí, Spain)

  Cervera, Marina; Bell, Simon; Muñoz, Francesc; Mishra, Himansu S.; Fleming, Lora E.; Grellier, James; Carrasco Turigas, Glòria; Nieuwenhuijsen, Mark J.; Vert Roca, Cristina, 1991-; Gascon Merlos, Mireia, 1984- (MDPI, 2021)

  The perception of the quality of green and blue spaces can be key in the relationship between a community and its local landscape (i.e., place identification). The lack of transdisciplinary training and social-specific ...
• Identifying chromosomal subpopulations based on their recombination histories advances the study of the genetic basis of phenotypic traits

  Ruiz Arenas, Carlos, 1990-; Cáceres, Alejandro; López, Marcos; Pelegrí-Sisó, Dolors; González, Josefa; González, Juan Ramón (Cold Spring Harbor Laboratory Press (CSHL Press), 2020)

  Recombination is a main source of genetic variability. However, the potential role of the variation generated by recombination in phenotypic traits, including diseases, remains unexplored because there is currently no ...
• The EU Child Cohort Network's core data: establishing a set of findable, accessible, interoperable and re-usable (FAIR) variables

  Pinot de Moira, Angela; Fernández-Barrés, Sílvia; Vrijheid, Martine; LifeCycle Project Group (Springer, 2021)

  The Horizon2020 LifeCycle Project is a cross-cohort collaboration which brings together data from multiple birth cohorts from across Europe and Australia to facilitate studies on the influence of early-life exposures on ...
• Heart healthy cities: genetics loads the gun but the environment pulls the trigger

  Münzel, Thomas; Sørensen, Mette; Lelieveld, Jos; Hahad, Omar; Al-Kindi, Sadeer; Nieuwenhuijsen, Mark J.; Giles-Corti, Billie; Daiber, Andreas; Rajagopalan, Sanjay T. (Oxford University Press, 2021)

  The world's population is estimated to reach 10 billion by 2050 and 75% of this population will live in cities. Two-third of the European population already live in urban areas and this proportion continues to grow. Between ...
• Associations between road traffic noise exposure at home and school and ADHD in school-aged children: the TRAILS study

  Zijlema, Wilma; de Kluizenaar, Y.; van Kamp, Irene; Hartman, Catharina A. (Springer, 2021)

  Environmental noise may play a role in the manifestation and severity of attention deficit/hyperactivity disorder (ADHD) symptoms, but evidence is limited. We investigated the cross-sectional associations between residential ...
• Genomic footprints of activated telomere maintenance mechanisms in cancer

  Sieverling, Lina; Hong, Chen; Koser, Sandra D.; Ginsbach, Philip; Kleinheinz, Kortine; Hutter, Barbara; Braun, Delia M.; Cortés-Ciriano, Isidro; Xi, Ruibin; Kabbe, Rolf; Park, Peter J.; Eils, Roland; Schlesner, Matthias; PCAWG Structural Variation Working Group; Brors, Benedikt; Rippe, Karsten; Jones, David T. W.; Feuerbach, Lars; PCAWG Consortium; Ossowski, Stephan; Estivill, Xavier, 1955- (Nature Research, 2020)

  Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ...
• A RAC-GEF network critical for early intestinal tumourigenesis

  Pickering, Karen; Unal, E. Besray; Kiel, Christina; Serrano Pubull, Luis, 1982-; Sansom, Owen J. (Nature Research, 2021)

  RAC1 activity is critical for intestinal homeostasis, and is required for hyperproliferation driven by loss of the tumour suppressor gene Apc in the murine intestine. To avoid the impact of direct targeting upon homeostasis, ...
• Iron replacement and redox balance in non-anemic and mildly anemic iron deficiency COPD patients: insights from a clinical trial

  Pérez-Peiró, Maria; Martín-Ontiyuelo, Clara; Rodó-Pin, Anna; Piccari, Lucilla; Admetlló Papiol, Mireia; Duran Jordà, Xavier, 1974-; Rodríguez Chiaradia, Diego Agustín; Barreiro Portela, Esther (MDPI, 2021)

  In COPD patients, non-anemic iron deficiency (NAID) is a common systemic manifestation. We hypothesized that in COPD patients with NAID, iron therapy may improve systemic oxidative stress. The FACE (Ferinject assessment ...
• Differences in nutritional status and inflammatory biomarkers between female and male patients with bronchiectasis: a large-cohort study

  Wang, Xuejie; Villa, Carmen; Dobarganes, Yadira; Olveira, Casilda; Girón, Rosa; García-Clemente, Marta; Máiz, Luis; Sibila, Oriol; Golpe, Rafael; Menéndez, Rosario; Rodríguez-López, Juan; Prados, Concepción; Martínez-García, Miguel Ángel; Rodriguez, Juan Luis; Rosa, David de la; Duran, Xavier; Barreiro Portela, Esther (MDPI, 2021)

  We hypothesized that systemic inflammatory and nutritional parameters may differ between male and female patients with non-CF bronchiectasis. In a large patient cohort from the Spanish Online Bronchiectasis Registry (RIBRON), ...
• Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study

  Wang, Gang; Casas Sanahuja, Maribel; Abellan, Alicia; García Aymerich, Judith; Sunyer Deu, Jordi; Melén, Erik (UNLISTED PUBLISHER, 2021)

  Background: The prevalences of obstructive and restrictive spirometric phenotypes, and their relation to early-life risk factors from childhood to young adulthood remain poorly understood. The aim was to explore these ...
• Snoring and nocturnal reflux: association with lung function decline and respiratory symptoms

  Emilsson, Össur Ingi; Hägg, Shadi Amid; Lindberg, Eva; Franklin, Karl; Torén, Kjell; Benediktsdóttir, Bryndís; Aspelund, Thor; Gómez Real, Francisco; Leynaert, Bénédicte; Demoly, Pascal; Sigsgaard, Torben; Perret, Jennifer L.; Malinovschi, Andrei; Jarvis, Deborah; García Aymerich, Judith; Gislason, Thorarinn; Janson, Christer (European Respiratory Society, 2019)

  Introduction: The study aim was to examine the association of snoring and nocturnal gastro-oesophageal reflux (nGOR) with respiratory symptoms and lung function, and if snoring and/or nGOR associated with a steeper decline ...
• Pharmacological treatment of asthma in a cohort of adults during a 20-year period: results from the European Community Respiratory Health Survey I, II and III

  Janson, Christer; García Aymerich, Judith; Jarvis, Deborah (European Respiratory Society, 2019)

  Asthma often remains uncontrolled, despite the fact that the pharmacological treatment has undergone large changes. We studied changes in the treatment of asthma over a 20-year period and identified factors associated with ...
• European Respiratory Society International Congress 2018: four shades of epidemiology and tobacco control

  de Vries, Maaike; Axson, Eleanor L.; Ratanachina, Jate; Dumas, Orianne; De Matteis, Sara; Bédard, Annabelle, 1986-; Roda, Célina; Moitra, Subhabrata; Dagli, Elif; Dimanti, Athina; Dilektasli, Asli Gorek; Ravara, Sofia; Amaral, André F.S. (European Respiratory Society, 2019)

  In this article, early career members and experienced members of the Epidemiology and Environment Assembly of the European Respiratory Society highlight and summarise a selection of six sessions from the Society's annual ...
• Maternal Mediterranean diet in pregnancy and newborn DNA methylation: a meta-analysis in the PACE Consortium

  Küpers, Leanne K.; Fernández-Barrés, Sílvia; Nounu, Aayah; Friedman, Chloe; Fore, Ruby; Mancano, Giulia; Dabelea, Dana; Rifas-Shiman, Sheryl L.; Mulder, Rosa H.; Oken, Emily; Johnson, Laura; Bustamante Pineda, Mariona; Jaddoe, Vincent W. V.; Hivert, Marie-France; Starling, Anne P.; de Vries, Jeanne H. M.; Sharp, Gemma C.; Vrijheid, Martine; Felix, Janine Frédérique (Taylor & Francis, 2022)

  Higher adherence to the Mediterranean diet during pregnancy is related to a lower risk of preterm birth and to better offspring cardiometabolic health. DNA methylation may be an underlying biological mechanism. We evaluated ...
• Risk of child poverty and social exclusion in two Spanish regions: social and family determinants

  González, Llúcia; Estarlich, Marisa; Murcia, Mario; Larrañaga, Isabel; Barreto, Florencia B.; Santa-Marina, Loreto; Arranz, Enrique; Cirugeda, Lourdes; Simó, Sandra; Rebagliato, Marisa (Elsevier, 2020)

  Objective: Describe the risk of poverty and social exclusion in children aged 8-11 years from Gipuzkoa and Valencia (Spain), through AROPE (At Risk Of Poverty or Social Exclusion) indicators, and evaluate their associated ...
• Nonparticipation selection bias in the MOBI-Kids Study

  Turner, Michelle C.; Gracia-Lavedan, Esther; Langer, Chelsea Eastman; Castaño Vinyals, Gemma; Albert, Alex; Badia, Francesc; Carretero, Gema; Cardis, Elisabeth (Lippincott Williams & Wilkins, 2019)

  Background: MOBI-Kids is a 14-country case-control study designed to investigate the potential effects of electromagnetic field exposure from mobile telecommunications devices on brain tumor risk in children and young ...
• The COVID-19 pandemic as a starting point to accelerate improvements in health in our cities through better urban and transport planning

  Nieuwenhuijsen, Mark J.; Hahad, Omar; Münzel, Thomas (Springer, 2022)
• The association between air pollutants and hippocampal volume from magnetic resonance imaging: A systematic review and meta-analysis

  Balboni, Erica; Filippini, Tommaso; Crous-Bou, Marta; Guxens Junyent, Mònica; Erickson, Lance D.; Vinceti, Marco (Elsevier, 2022)

  Growing epidemiological evidence suggests that air pollution may increase the risk of cognitive decline and neurodegenerative disease. A hallmark of neurodegeneration and an important diagnostic biomarker is volume reduction ...

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