• CoDysAn: A telemedicine tool to improve awareness and diagnosis for patients with congenital dyserythropoietic anemia

  Tornador Antolin, Cristian, 1979-; Sánchez Prados, Edgar; Cadenas, Beatriz; Russo, Roberta; Venturi, Veronica; Andolfo, Immacolata; Hernández Rodriguez, Ines; Iolascon, Achille; Sánchez, Mayka (Frontiers, 2019)

  Congenital Dyserythropoietic Anemia (CDA) is a heterogeneous group of hematological disorders characterized by chronic hyporegenerative anemia and distinct morphological abnormalities of erythroid precursors in the bone ...
• Closing the gap between therapeutic use and mode of action in remedial herbs

  Olivés Farrés, Joaquim, 1987-; Mestres i López, Jordi (Frontiers, 2019)

  The ancient tradition of taking parts of a plant or preparing plant extracts for treating certain discomforts and maladies has long been lacking a scientific rationale to support its preparation and still widespread use ...
• License to kill? Domestic cats affect a wide range of native fauna in a highly biodiverse mediterranean country

  Mori, Emiliano; Menchetti, Mattia; Camporesi, Alberto; Cavigioli, Luca; Tabarelli de Fatis, Karol; Girardello, Marco (Frontiers, 2019)

  Amongst domestic animals, the domestic cat, Felis catus, is widely considered to be one of the most serious threats to wildlife conservation. This is particularly evident for island ecosystems, as data for mainland countries ...
• Organophosphate pesticide metabolite concentrations in urine during pregnancy and offspring nonverbal IQ at age 6 years

  Jusko, Todd A.; van den Dries, Michiel; Pronk, Anjoeka; Shaw, Pamela A.; Guxens Junyent, Mònica; Spaan, Suzanne; Jaddoe, Vincent W. V.; Tiemeier, Henning; Longnecker, Matthew P. (National Institute of Environmental Health Sciences (NIEHS), 2019)

  Background: Susceptibility to organophosphate (OP) pesticide neurotoxicity may be greatest during the prenatal period; however, previous studies have produced mixed findings concerning in utero OP pesticide exposure and ...
• Does the oxidative stress play a role in the associations between outdoor air pollution and persistent asthma in adults? Findings from the EGEA study

  Havet, Anaïs; Li, Zhen; Zerimech, Farid; Sanchez, Margaux; Siroux, Valérie; Le Moual, Nicole; Brunekreef, Bert; Künzli, Nino; Jacquemin Leonard, Bénédicte; Varraso, Raphaëlle; Matran, Regis; Nadif, Rachel (BioMed Central, 2019)

  Background: Evidences that oxidative stress plays a role in the associations between outdoor air pollution and asthma are growing. We aimed to study the role of plasma fluorescent oxidation products levels (FlOPs; an ...
• Associations of black carbon with lung function and airway inflammation in schoolchildren

  Paunescu, Alexandra-Cristina; Casas Sanahuja, Maribel; Ferrero, Amparo; Pañella, Pau; Bougas, Nicolas; Beydon, Nicole; Just, Jocelyne; Lezmi, Guillaume; Sunyer Deu, Jordi; Ballester Díez, Ferran; Momas, Isabelle (Elsevier, 2019)

  Background: Few studies have investigated the 24-hour respiratory health effects of personal black carbon (BC) and ultrafine particles (UFP) exposure in schoolchildren. The objective of this study was to investigate these ...
• Organophosphate pesticide metabolite concentrations in urine during pregnancy and offspring attention-deficit hyperactivity disorder and autistic traits

  van den Dries, Michiel; Guxens Junyent, Mònica; Pronk, Anjoeka; Spaan, Suzanne; El Marroun, Hanan; Jusko, Todd A.; Longnecker, Matthew P.; Ferguson, Kelly K.; Tiemeier, Henning (Elsevier, 2019)

  Background: Prenatal exposure to organophosphate (OP) pesticides has been associated with altered neuronal cell development and behavioral changes in animal offspring. However, the few studies investigating the association ...
• A decade of structural variants: description, history and methods to detect structural variation

  Escaramís, Geòrgia; Docampo, Elisa; Rabionet, Raquel (Oxford University Press, 2015)

  In the past decade, the view on genomic structural variation (SV) has been changed completely. SVs, previously considered rare events, are now recognized as the largest source of interindividual genetic variation affecting ...
• Validation of self-reported perception of proximity to industrial facilities: MCC-Spain study

  Castelló, Adela; Castaño Vinyals, Gemma; O'Callaghan Gordo, Cristina; Kogevinas, Manolis; García-Pérez, Javier (Elsevier, 2020)

  Background: Self-reported data about environmental exposures can lead to measurement error. Objectives: To validate the self-reported perception of proximity to industrial facilities. Methods: MCC-Spain is a population-based ...
• Lack of association between particulate air pollution and blood glucose levels and diabetic status in peri-urban India

  Curto Tirado, Ariadna, 1987-; Ranzani, Otavio; Milà, Carles; Sanchez, Margaux; Marshall, Julian D.; Kulkarni, Bharati; Bhogadi, Santhi; Kinra, Sanjay; Wellenius, Gregory A.; Tonne, Cathryn (Elsevier, 2019)

  Background: Limited evidence exists on the effect of particulate air pollution on blood glucose levels. We evaluated the associations of residential and personal levels of fine particulate matter (PM2.5) and black carbon ...
• Long-term exposure to atmospheric metals assessed by mosses and mortality in France

  Lequy, Emeline; Siemiatycki, Jack; Leblond, Sébastien; Meyer, Caroline; Zhivin, Sergey; Vienneau, Danielle; de Hoogh, Kees; Goldberg, Marcel; Zins, Marie; Jacquemin Leonard, Bénédicte (Elsevier, 2019)

  Background: Long-term exposure to air pollution affects health, but little is known about exposure to atmospheric metals. Estimating exposure to atmospheric metals across large spatial areas remains challenging. Metal ...
• Hemimetabolous insects elucidate the origin of sexual development via alternative splicing

  Wexler, Judith; Delaney, Emily Kay; Belles, Xavier; Schal, Coby; Wada-Katsumata, Ayako; Amicucci, Matthew J.; Kopp, Artyom (eLife, 2019)

  Insects are the only known animals in which sexual differentiation is controlled by sex-specific splicing. The doublesex transcription factor produces distinct male and female isoforms, which are both essential for ...
• Aquatic Coleoptera of North Oman, with description of new species of Hydraenidae and Hydrophilidae

  Ribera, Ignacio; Hernando, Carles; Cieslak, Alexandra (Sciendo, 2019)

  We report the aquatic Coleoptera (families Dryopidae, Dytiscidae, Georissidae, Gyrinidae, Heteroceridae, Hydraenidae, Hydrophilidae and Limnichidae) from North Oman, mostly based on the captures of fourteen localities ...
• Intrapulmonary concentrations of meropenem administered by continuous infusion in critically ill patients with nosocomial pneumonia: a randomized pharmacokinetic trial

  Benítez-Cano, Adela; Luque Pardos, Sònia; Sorli Redó, M. Luisa; Carazo Cordobés, Jesús; Ramos Delgado, M.; Campillo Ambrós, Núria; Curull Serrano, Víctor; Sánchez-Font, Albert; Vilaplana, Carles; Horcajada Gallego, Juan Pablo; Adalia Bartolomé, Ramón; Bermejo Martínez, Silvia; Samsó Sabé, Enric; Hope, William; Grau Cerrato, Santiago (BioMed Central, 2020)

  Background: Optimal antimicrobial drug exposure in the lung is required for successful treatment outcomes for nosocomial pneumonia. Little is known about the intrapulmonary pharmacokinetics (PK) of meropenem when administered ...
• Clinical interest of LMO2 testing for the diagnosis of aggressive large B-Cell lymphomas

  Vazquez de las Heras, Ivonne; Papaleo, Natalia; García, Eugenia; Salido Galeote, Marta; Salar Silvestre, Antonio; Hernández Llodrà, Sílvia; Calvo Gonzalo, Xavier; Colomo Saperas, Luis Alberto (MDPI, 2020)

  MYC rearrangements usually confer aggressive biological behavior to large B-cell lymphomas. In this study, we aimed to evaluate the relevance of LMO2 detection to the clinical approach to these tumors. First, the ability ...
• A unicellular relative of animals generates a layer of polarized cells by actomyosin-dependent cellularization

  Dudin, Omaya; Ondracka, Andrej; Grau Bové, Xavier; Haraldsen, Arthur A. B.; Toyoda, Atsushi; Suga, Hiroshi; Bråte, Jon; Ruiz Trillo, Iñaki (eLife, 2019)

  In animals, cellularization of a coenocyte is a specialized form of cytokinesis that results in the formation of a polarized epithelium during early embryonic development. It is characterized by coordinated assembly of an ...
• The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi’s sarcoma-associated herpesvirus

  Baquero Pérez, Belinda; Antanaviciute, Agne; Yonchev, Ivaylo D.; Carr, Ian M.; Wilson, Stuart A.; Whitehouse, Adrian (eLife, 2019)

  N6-methyladenosine (m6A) is the most abundant internal RNA modification of cellular mRNAs. m6A is recognised by YTH domain-containing proteins, which selectively bind to m6A-decorated RNAs regulating their turnover and ...
• Heat tolerance and acclimation capacity in subterranean arthropods living under common and stable thermal conditions

  Pallarés, Susana; Colado, Raquel; Pérez Fernández, Toni; Wesener, Thomas; Ribera, Ignacio; Sánchez Fernández, David (Wiley-Blackwell, 2019)

  Cave-dwelling ectotherms, which have evolved for millions of years under stable thermal conditions, could be expected to have adjusted their physiological limits to the narrow range of temperatures they experience and to ...
• Bacterial communities within Phengaris (Maculinea) alcon caterpillars are shifted following transition from solitary living to social parasitism of Myrmica ant colonies

  Szenteczki, Mark A.; Pitteloud, Camille; Casacci, Luca P.; Kešnerová, Lucie; Whitaker, Melissa R. L.; Engel, Philipp; Vila, Roger; Alvarez, Nadir (Wiley-Blackwell, 2019)

  Bacterial symbionts are known to facilitate a wide range of physiological processes and ecological interactions for their hosts. In spite of this, caterpillars with highly diverse life histories appear to lack resident ...
• Narrow-band imaging and high-definition white-light endoscopy in patients with serrated lesions not fulfilling criteria for serrated polyposis syndrome: a randomized controlled trial with tandem colonoscopy

  Riu Pons, Fausto; Andreu García, Montserrat; Naranjo‐Hans, Dolores; Álvarez-González, Marco Antonio; Seoane, Agustín; Dedeu Cusco, Josep Maria; Barranco Priego, Luis Eugenio; Bessa Caserras, Xavier (BioMed Central, 2020)

  Background: It is unknown whether narrow-band imaging (NBI) could be more effective than high-definition white-light endoscopy (HD-WLE) in detecting serrated lesions in patients with prior serrated lesions > 5 mm not ...

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