• Drinking water nitrate and human health: an updated review

  Ward, Mary H.; Jones, Rena R.; Brender, Jean D.; Kok, Theo M. de; Weyer, Peter J.; Nolan, Bernard T.; Villanueva, Cristina M.; van Breda, Simone G. (MDPI, 2018)

  Nitrate levels in our water resources have increased in many areas of the world largely due to applications of inorganic fertilizer and animal manure in agricultural areas. The regulatory limit for nitrate in public drinking ...
• The gut microbiome profile in obesity: a systematic review

  Castañer, Olga; Goday Arno, Alberto; Park, Yong-Moon; Lee, Seung-Hwan; Magkos, Faidon; Shiow, Sue-Anne Toh Ee; Schröder, Helmut, 1958- (Hindawi, 2018)
• Is iron deficiency modulating physical activity in COPD?

  Martín-Ontiyuelo, Clara; Rodó-Pin, Anna; Sancho Muñoz, Antonio; Martinez-Llorens, Juana María; Admetlló Papiol, Mireia; Molina Ferragut, Luis; Gea Guiral, Joaquim; Barreiro Portela, Esther; Rodríguez Chiaradía, Diego A. (DOVE Medical Press, 2019)

  There is evidence that iron plays a key role in the adequate functioning of skeletal muscle. While it has been demonstrated that nonanemic iron deficiency (NAID) affects exercise tolerance and response to exercise training ...
• Effect of mistimed eating patterns on breast and prostate cancer risk (MCC-Spain Study)

  Kogevinas, Manolis; Espinosa Díaz, Ana; Papantoniou, Kyriaki, 1983-; Castaño Vinyals, Gemma; Romaguera Bosch, Dora (Wiley-Blackwell, 2018)

  Modern life involves mistimed sleeping and eating patterns that in experimental studies are associated with adverse health effects. We assessed whether timing of meals is associated with breast and prostate cancer risk ...
• Insulin-like growth factor levels and chronic lymphocytic leukaemia: results from the MCC-Spain and EpiLymph-Spain studies

  Casabonne, Delphine; Benavente, Yolanda; Costas, Laura; Robles Hellín, Claudia, 1980-; González, Eva; de la Banda, Esmeralda; Alonso, Esther; Aymerich, Marta; Campo, Elias; Marcos-Gragera, Rafael; Tardón, Adonina; Olmedo-Requena, Rocío; Gimeno Vázquez, Eva; Martınez-Lopez, Alba; Casanovas, Oriol; Castaño Vinyals, Gemma; Aragonés, Núria; Pollan, Marina; Kogevinas, Manolis; de Sanjosé, Silvia (Wiley-Blackwell, 2019)
• Health-related quality of life in men with prostate cancer undergoing active surveillance versus radical prostatectomy, external-beam radiotherapy, prostate brachytherapy and reference population: a cross-sectional study

  Sureda Gomila, Antoni; Fumadó Ciutat, Lluis; Ferrer Forés, Montserrat; Garín, O.; Bonet, X.; Mir, M.C.; Abascal, J.M.; Vigués, F.; Cecchini, L.; Suárez Novo, José Francisco (BioMed Central, 2019)

  BACKGROUND: The purpose of this study is to describe Health-Related Quality of Life (HRQoL) of localized prostate cancer patients in an Active Surveillance (AS) program, and to compare them with those undergoing radical ...
• Occupational exposures and 20-year incidence of COPD: the European Community Respiratory Health Survey

  Lytras, Theodoros, 1987-; Kogevinas, Manolis; Carsin, Anne-Elie; Antó i Boqué, Josep Maria; García Aymerich, Judith; Zock, Jan-Paul (BMJ Publishing Group, 2018)

  Background: Occupational exposures have been associated with an increased risk of COPD. However, few studies have related objectively assessed occupational exposures to prospectively assessed incidence of COPD, using ...
• DNA methylation in childhood asthma: an epigenome-wide meta-analysis

  Xu, Chengjian; Bustamante Pineda, Mariona; García Aymerich, Judith; Antó i Boqué, Josep Maria; Sunyer Deu, Jordi; Koppelman, Gerard H. (Elsevier, 2018)

  Background: DNA methylation profiles associated with childhood asthma might provide novel insights into disease pathogenesis. We did an epigenome-wide association study to assess methylation profiles associated with childhood ...
• Urban upbringing and childhood respiratory and allergic conditions: A multi-country holistic study

  Tischer, Christina; Dadvand, Payam; Basagaña Flores, Xavier; Sunyer Deu, Jordi; Antó i Boqué, Josep Maria (Elsevier, 2018)

  Objective: We integratively assessed the effect of different indoor and outdoor environmental exposures early in life on respiratory and allergic health conditions among children from (sub-) urban areas. Methods: This study ...
• Zipf's Law, unbounded complexity and open-ended evolution

  Corominas Murtra, Bernat; Seoane, Luís F., 1985-; Solé Vicente, Ricard, 1962- (Royal Society, 2018)

  A major problem for evolutionary theory is understanding the so-called open-ended nature of evolutionary change, from its definition to its origins. Open-ended evolution (OEE) refers to the unbounded increase in complexity ...
• Differentiating resting brain states using ordinal symbolic analysis

  Quintero-Quiroz, Carlos; Montesano, Luis; Pons, Antonio J.; Torrent, Maria Carme; García Ojalvo, Jordi; Masoller, Cristina (American Institute of Physics (AIP), 2018)

  Symbolic methods of analysis are valuable tools for investigating complex time-dependent signals. In particular, the ordinal method defines sequences of symbols according to the ordering in which values appear in a time ...
• The associations of earlier trauma exposures and history of mental disorders with PTSD after subsequent traumas

  Kessler, Ronald C.; Alonso Caballero, Jordi; WHO World Mental Health Survey Collaborators (Nature Research, 2018)

  Although earlier trauma exposure is known to predict posttraumatic stress disorder (PTSD) after subsequent traumas, it is unclear whether this association is limited to cases where the earlier trauma led to PTSD. Resolution ...
• Post-traumatic stress disorder associated with sexual assault among women in the WHO World Mental Health Surveys

  Scott, Kate M.; Koenen, Karestan C.; King, Andrew; Petukhova, Maria; Alonso Caballero, Jordi; Bromet, Evelyn J.; Bruffaerts, Ronny; Bunting, Brentan; de Jonge, Peter; Haro Abad, Josep Maria; Karam, Elie G.; Lee, Sing; Medina Mora, Maria Elena; Navarro Mateu, Fernando; Sampson, Nancy A.; Shahly, Victoria; Stein, Dan J.; Torres, Yolanda; Zaslavsky, Alan M.; Kessler, Ronald C. (Cambridge University Press, 2018)

  Background: Sexual assault is a global concern with post-traumatic stress disorder (PTSD), one of the common sequelae. Early intervention can help prevent PTSD, making identification of those at high risk for the disorder ...
• Simulations meet machine learning in structural biology

  Pérez, Adrià; Martínez Rosell, Gerard; De Fabritiis, Gianni (Elsevier, 2018)

  Classical molecular dynamics (MD) simulations will be able to reach sampling in the second timescale within five years, producing petabytes of simulation data at current force field accuracy. Notwithstanding this, MD will ...
• Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

  GBD 2017 DALYs and HALE Collaborators (Elsevier, 2018)

  Background: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, ...
• Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017

  GBD 2017 SDG Collaborators (Elsevier, 2018)

  Background: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver ...
• Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017

  GBD 2017 Population and Fertility Collaborators (Elsevier, 2018)

  Background: Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates ...
• Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017

  GBD 2017 Risk Factor Collaborators (Elsevier, 2018)

  Background: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising ...
• Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

  GBD 2017 Causes of Death Collaborators (Elsevier, 2018)

  Background: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 ...
• Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017

  GBD 2017 Mortality Collaborators (Elsevier, 2018)

  Background: Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of ...

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