Welcome to the UPF Digital Repository

Articles (Departament de Ciències Experimentals i de la Salut)

Articles (Departament de Ciències Experimentals i de la Salut)

 

Articles de recerca, en accés obert, del Departament de Ciències Experimentals i de la Salut de la UPF.

Recent Submissions

  • Pinto, Sandra N.; Dias, Susana A.; Cruz, Ana F.; Mil-Homens, Dalila; Fernandes, Fabio; Valle, Javier; Andreu Martínez, David; Prieto, Manuel; Castanho, Miguel A.R.B.; Coutinho, Ana; Salomé Veiga, Ana (Oxford University Press, 2019)
    Objectives: To investigate the mechanism of action at the molecular level of pepR, a multifunctional peptide derived from the Dengue virus capsid protein, against Staphylococcus aureus biofilms. Methods: Biofilm mass, ...
  • Fuertes, Elaine; Carsin, Anne-Elie; Garcia-Larsen, Vanessa; Guerra, Stefano; Pin, Isabelle; Leynaert, Bénédicte; Accordini, Simone; Martínez-Moratalla, Jesús; Antó i Boqué, Josep Maria; Urrutia, Isabel; Le Gouellec, Audrey; Heinrich, Joachim; Gislason, Thorarinn; Jõgi, Rain; Janson, Christer; Jarvis, Debbie; García Aymerich, Judith (Public Library of Science (PLoS), 2019)
    Objective: Regular physical activity may be associated with improved lung function via reduced systemic inflammation, although studies exploring this mechanism are rare. We evaluated the role of C-reactive protein in blood, ...
  • Ballester, Laura; Alayo, Itxaso; Vilagut Saiz, Gemma, 1975-; Blasco Cubedo, Maria Jesús; Mortier, Philippe; Alonso Caballero, Jordi; UNIVERSAL study group (Public Library of Science (PLoS), 2019)
    Objective: To assess the accuracy of WMH-ICS online screening scales for evaluating four common mental disorders (Major Depressive Episode[MDE], Mania/Hypomania[M/H], Panic Disorder[PD], Generalized Anxiety Disorder[GAD]) ...
  • Soldevila-Domenech, Natalia; Boronat Rigol, Anna; Mateus Rodriguez, Julian Andrés; Diaz-Pellicer, Patricia; Matilla, Iris; Pérez-Otero, Marta; Aldea-Perona, Ana; Torre Fornell, Rafael de la (MDPI, 2019)
    Beer and wine contains the simple phenol tyrosol (TYR) which is endogenously converted into hydroxytyrosol (HT), one of the strongest dietary antioxidants, by CYP2A6 and CYP2D6 polymorphic enzymes. We investigated in humans ...
  • Dasilva, Miguel; Navarro-Guzman, Alvaro; Ortiz Romero, Paula; Camassa, Alessandra; Muñoz-Cespedes, Alberto; Campuzano Uceda, María Victoria; Sanchez-Vives, Maria V. (Springer, 2019)
    Williams-Beuren syndrome (WBS) is a rare neurodevelopmental disorder characterized by moderate intellectual disability and learning difficulties alongside behavioral abnormalities such as hypersociability. Several structural ...
  • Baclaocos, Janinah; Santesmasses Ruiz, Didac, 1978-; Mariotti, Marco, 1984-; Bierla, Katarzyna; Vetick, Michael B.; Lynch, Sharon; McAllen, Rob; Mackrill, John J.; Loughran, Gary; Guigó Serra, Roderic; Szpunar, Joanna; Copeland, Paul R.; Gladyshev, Vadim N.; Atkins, John F. (Elsevier, 2019)
    Selenoproteins typically contain a single selenocysteine, the 21st amino acid, encoded by a context-redefined UGA. However, human selenoprotein P (SelenoP) has a redox-functioning selenocysteine in its N-terminal domain ...
  • Salazar, Vivian A.; Arranz-Trullén, Javier; Prats-Ejarque, Guillem; Torrent, Marc; Andreu Martínez, David; Pulido, David; Boix, Ester (MDPI, 2019)
    Candida albicans is a polymorphic fungus responsible for mucosal and skin infections. Candida cells establish themselves into biofilm communities resistant to most currently available antifungal agents. An increase of ...
  • Fructuoso, Marta; Espinosa-Carrasco, José; Erb, Ionas; Notredame, Cedric; Dierssen, Mara (Bio-protocol, 2019)
    Obesity is an important health problem with a strong environmental component that is acquiring pandemic proportion. The high availability of caloric dense foods promotes overeating potentially causing obesity. Animal models ...
  • Mas Sandoval, Àlex, 1989-; Arauna, Lara R; Gouveia, Mateus H.; Barreto, Mauricio L.; Horta, Bernardo L.; Lima-Costa, Maria Fernanda; Pereira, Alexandre C.; Salzano, Francisco Mauro; Hünemeier, Tábita; Tarazona-Santos, Eduardo; Bortolini, Maria Cátira; Comas, David, 1969- (Oxford University Press, 2019)
    After the colonization of the Americas by Europeans and the consequent Trans-Atlantic Slave Trade, most Native American populations in eastern Brazil disappeared or went through an admixture process that configured a ...
  • Soldevila-Domenech, Natalia; Boronat Rigol, Anna; Langohr, Klaus; Torre Fornell, Rafael de la (Frontiers, 2019)
    Longer life expectancy has led to an increase in the prevalence of age-related cognitive decline and dementia worldwide. Due to the current lack of effective treatment for these conditions, preventive strategies represent ...
  • Mortamais, Marion; Pujol Martí, Jesús, 1981-; Martínez-Vilavella, Gerard; Fenoll, Raquel; Reynes, Christelle; Sabatier, Robert; Rivas, Ioar; Forns i Guzman, Joan, 1981-; Vilor Tejedor, Natàlia, 1988-; Alemany, Silvia; Cirach, Marta; Alvarez-Pedrerol, Mar; Nieuwenhuijsen, Mark J.; Sunyer Deu, Jordi (Elsevier, 2019)
    Objective: Air pollution (AP) may affect neurodevelopment, but studies about the effects of AP on the growing human brain are still scarce. We aimed to investigate the effects of prenatal exposure to AP on lateral ventricles ...
  • Carmona, Mercè; de Cubas, Laura; Bautista, Eric; Moral-Blanch, Marta; Medrano-Fernández, Iria; Sitia, Roberto; Boronat i Llop, Susanna, 1965-; Ayté del Olmo, José; Hidalgo Hernando, Elena (Nature Research, 2019)
    Genetically encoded probes monitoring H2O2 fluctuations in living organisms are key to decipher redox signaling events. Here we use a new probe, roGFP2-Tpx1.C169S, to monitor pre-toxic fluctuations of peroxides in fission ...
  • Marte, Luis; Boronat i Llop, Susanna, 1965-; García Santamarina, Sarela, 1978-; Ayté del Olmo, José; Kitamura, Kenji; Hidalgo Hernando, Elena (Elsevier, 2019)
    Signaling cascades respond to specific inputs, but also require active interventions to be maintained in their basal/inactive levels in the absence of the activating signal(s). In a screen to search for protein quality ...
  • Irastorza-Azcarate, Ibai; Castaño-Díez, Daniel; Devos, Damien P.; Gallego, Oriol (Elsevier, 2019)
    Historically, structural biology has been largely centered on in vitro approaches as the dominant technique to obtain indispensable high-resolution data. In situ structural biology is now poised to contribute with ...
  • Garrido, Romina; Trowbridge, Casandra A.; Tamura, Nana (Public Library of Science (PLoS), 2019)
  • Jorcano, Ainhoa; Lubczynska, Malgorzata Joanna; Pierotti, Livia; Sunyer Deu, Jordi; Guxens Junyent, Mònica (Elsevier, 2019)
    Background: The association between air pollution exposure and emotional and behavioural problems in children is unclear. We aimed to assess prenatal and postnatal exposure to several air pollutants and child's depressive ...
  • Ghosh, Eshan; Dwivedi, Hemlata; Baidya, Mithu; Srivastava, Ashish; Kumari, Punita; Stepniewski, Tomek; Kim, Hee Ryung; Lee, Mi-Hye; van Gastel, Jaana; Chaturvedi, Madhu; Roy, Debarati; Pandey, Shubhi; Maharana, Jagannath; Guixà González, Ramon, 1978-; Luttrell, Louis M.; Chung, Ka Young; Dutta, Somnath; Selent, Jana; Shukla, Arun K. (Elsevier, 2019)
    Desensitization, signaling, and trafficking of G-protein-coupled receptors (GPCRs) are critically regulated by multifunctional adaptor proteins, β-arrestins (βarrs). The two isoforms of βarrs (βarr1 and 2) share a high ...
  • Hohmann, Cynthia; Keller, Theresa; Gehring, Ulrike; Wijga, Alet; Standl, Marie; Kull, Inger; Bergström, Anna; Lehmann, Irina; von Berg, Andrea; Heinrich, Joachim; Lau, Susanne; Wahn, Ulrich; Maier, Dieter; Antó i Boqué, Josep Maria; Bousquet, Jean; Smit, Henriëtte A.; Keil, Thomas; Roll, Stephanie (BMJ Publishing Group, 2019)
    Introduction To understand the puberty-related sex shift in the prevalence of asthma and rhinitis as single entities and as respiratory multimorbidities, we investigated if there is also a sex-specific and puberty-related ...
  • Dobón Berenguer, Begoña, 1987-; Montanucci, Ludovica, 1978-; Peretó, Juli; Bertranpetit, Jaume, 1952-; Laayouni, Hafid, 1968- (BioMed Central, 2019)
    Background: Determining the factors involved in the likelihood of a gene being under adaptive selection is still a challenging goal in Evolutionary Biology. Here, we perform an evolutionary analysis of the human metabolic ...
  • Fernández-Barral, Asunción; Costales-Carrera, Alba; Buira, Sandra P.; Jung, Peter; Ferrer Mayorga, Gemma; Larriba, María Jesús; Bustamante-Madrid, Pilar; Domínguez, Orlando; Real, Francisco X.; Guerra Pastrián, Laura; Lafarga, Miguel; García-Olmo, Damián; Cantero, Ramón; Del Peso, Luis; Batlle Gómez, Eduard; Rojo, Federico; Muñoz, Alberto; Barbáchano, Antonio (Wiley-Blackwell, 2019)
    Intestine is a major target of vitamin D and several studies indicate an association between vitamin D deficiency and inflammatory bowel diseases (IBD), but also increased colorectal cancer (CRC) risk and mortality. However, ...

View more