• Oral fluid testing: promises and pitfalls

  Huestis, Marylin A.; Verstraete, Alain; Kwong, Tai C.; Morland, Jorg; Vincent, Michael J.; Torre Fornell, Rafael de la (American Association for Clinical Chemistry, 2011)

  Oral fluid is a promising new matrix for drug-testing programs for drug treatment, the workplace, pain management, and driving under the influence of drugs (DUID)7. As with any new technology, there are strengths and ...
• High and low suicidality in Europe: a fine-grained comparison of France and Spain within the ESEMeD surveys

  Kovess, Viviane; Boyd, Anders; Haro Abad, Josep Maria; Bruffaerts, Ronny; Vilagut Saiz, Gemma, 1975-; Lépine, Jean-Pierre; Gasquet, Isabelle; Alonso Caballero, Jordi (Elsevier, 2011)

  BACKGROUND: Suicidality risk-factors between countries with similar economic and religious background have been rarely compared, especially within genders. METHODS: Lifetime prevalence of suicide ideation, plans, and ...
• Comorbidity and disease burden in the National Comorbidity Survey Replication (NCS-R)

  Gadermann, Anne M.; Alonso Caballero, Jordi; Vilagut Saiz, Gemma, 1975-; Zaslavsky, Alan M.; Kessler, Ronald C. (Wiley-VCH Verlag, 2012)

  BACKGROUND: Disease burden estimates rarely consider comorbidity. Using a recently developed methodology for integrating information about comorbidity into disease burden estimates, we examined the comparative burdens of ...
• A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

  Vincent, Theresa; Neve, Etienne P.A.; Johnson, Jill R.; Kukalev, Alexander; Rojo, Federico; Albanell Mestres, Joan; Pietras, Kristian; Virtanen, Ismo; Philipson, Lennart; Leopold, Philip L.; Crystal, Ronald G.; García de Herreros, Antonio; Moustakas, Aristidis; Petterson, Ralf F.; Fuxe, Jonas (Nature Research, 2009)

  Epithelial-mesenchymal transition (EMT) is essential for organogenesis and is triggered during carcinoma progression to an invasive state. Transforming growth factor-beta (TGF-beta) cooperates with signalling pathways, ...
• Neurobiological mechanisms involved in nicotine dependence and reward: participation of the endogenous opioid system

  Berrendero Díaz, Fernando, 1971-; Robledo, Patricia, 1958-; Trigo i Rodríguez, Josep M.; Martín García, Elena, 1975-; Maldonado, Rafael, 1961- (Elsevier, 2010)

  Nicotine is the primary component of tobacco that maintains the smoking habit and develops addiction. The adaptive changes of nicotinic acetylcholine receptors produced by repeated exposure to nicotine play a crucial role ...
• Network, transcriptomic and genomic features differentiate genes relevant for drug response

  Piñero González, Janet, 1977-; Gonzalez-Perez, Abel; Guney, Emre; Aguirre Plans, Joaquim; Sanz, Ferran; Oliva Miguel, Baldomero; Furlong, Laura I., 1971- (Frontiers, 2018)

  Understanding the mechanisms underlying drug therapeutic action and toxicity is crucial for the prevention and management of drug adverse reactions, and paves the way for a more efficient and rational drug design. The ...
• Factor structure of the spanish version of the Edinburgh postnatal depression scale

  Gutierrez-Zotes, Alfonso; Gallardo-Pujol, David; Labad, Javier; Martín Santos, Rocío; García-Esteve, Luisa; Gelabert, Estel; Jover, Manuel; Guillamat, Roser; Mayoral, Fermín; Gornemann, Isolde; Canellas, Francesca; Gratacós Mayora, Mònica; Guitart, Miriam; Roca, Miquel; Costas, Javier; Ivorra, Jose Luis; Navinés, Ricard; Diego, Yolanda de; Vilella, Elisabet; Sanjuan, Julio (STM Editores, 2018)

  INTRODUCTION: The Edinburgh Postnatal Depression Scale (EPDS) is considered the gold standard in screening for postpartum depression. Although the Spanish version has been widely used, its factorial structure has not yet ...
• A single nucleotide polymorphism tags variation in the arylamine N-acetyltransferase 2 phenotype in populations of European background

  García Closas, Montserrat; Hein, David W.; Silverman, Debra T.; Malats i Riera, Núria; Yeager, Meredith; Jacobs, Kevin; Doll, Mark A.; Figueroa, Jonine D.; Baris, Dalsu; Schwenn, Molly; Kogevinas, Manolis; Johnson, Alison; Chatterjee, Nilanjan; Moore, Lee E.; Moeller, Timothy; Real, Francisco X.; Chanock, Stephen J.; Rothman, Nathaniel (Lippincott Williams & Wilkins, 2011)

  The arylamine N-acetyltransferase 2 (NAT2) slow acetylation phenotype is an established risk factor for urinary bladder cancer. We reported earlier on this risk association using NAT2 phenotypic categories inferred from ...
• A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

  Rothman, Nathaniel; Real, Francisco X.; Serra, Consol; Lloreta Trull, Josep, 1958-; Chanock, Stephen J. (Nature Research, 2010)

  We conducted a multi-stage, genome-wide association study of bladder cancer with a primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of European descent from five studies followed by a ...
• International network of cancer genome projects

  The International Cancer Genome Consortium (Nature Research, 2010)

  The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across ...
• Power and sample size calculations for longitudinal studies comparing rates of change with a time-varying exposure

  Basagaña Flores, Xavier; Liao, Xiaomei; Spiegelman, Donna (Wiley-VCH Verlag, 2010)

  Existing study design formulas for longitudinal studies assume that the exposure is time invariant or that it varies in a manner that is controlled by design. However, in observational studies, the investigator does not ...
• Socioeconomic inequalities in the use of dental care services in Europe: what is the role of public coverage?

  Palència Fernàndez, Laia; Espelt Hernández, Albert, 1981-; Cornejo Ovalle, Marco, 1969-; Borrell i Thió, Carme (Wiley-VCH Verlag, 2014)

  OBJECTIVES: The aim of this study was to analyse inequalities in the use of dental care services according to socioeconomic position (SEP) in individuals aged ≥50 years in European countries in 2006, to examine the association ...
• Power and sample size calculations for longitudinal studies estimating a main effect of a time-varying exposure

  Basagaña Flores, Xavier; Spiegelman, Donna (SAGE Publications, 2011)

  Existing study design formulas for longitudinal studies have assumed that the exposure is time-invariant. We derived sample size formulas for studies comparing rates of change by exposure when the exposure varies with time ...
• Cholinergic modulation of event-related oscillations (ERO)

  Sanchez-Alavez, Manuel; Robledo, Patricia, 1958-; Wills, Derek N.; Havstad, James; Ehlers, Cindy L. (Elsevier, 2014)

  The cholinergic system in the brain modulates patterns of activity involved in general arousal, attention processing, memory and consciousness. In the present study we determined the effects of selective cholinergic lesions ...
• Storage conditions and stability of global DNA methylation in placental tissue

  Vilahur Chiaraviglio, Nadia, 1982-; Baccarelli, Andrea A.; Bustamante Pineda, Mariona; Agramunt, Silvia; Byun, Hyang-Min; Fernandez, Mariana F.; Sunyer Deu, Jordi; Estivill, Xavier, 1955- (Future Medicine, 2013)

  AIM: The placenta is an informative and easily available tissue for many epidemiological studies. We analyzed the extent to which storage delay affects DNA methylation. MATERIAL & METHODS: Biopsies from two placentas were ...
• The effects of co-morbidity in defining major depression subtypes associated with long-term course and severity

  Wardenaar, Klaas J.; Alonso Caballero, Jordi; Kessler, Ronald C. (Cambridge University Press, 2014)

  BACKGROUND: Although variation in the long-term course of major depressive disorder (MDD) is not strongly predicted by existing symptom subtype distinctions, recent research suggests that prediction can be improved by using ...
• Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop

  Bousquet, Jean; Antó i Boqué, Josep Maria; Pinart, Mariona; Gergen, Peter J. (Elsevier, 2014)

  Population-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases. More than 130 birth cohorts focusing on asthma and allergy have been initiated ...
• Subthreshold posttraumatic stress disorder in the world health organization world mental health surveys

  McLaughlin, Katie A.; Alonso Caballero, Jordi; Kessler, Ronald C. (Elsevier, 2015)

  BACKGROUND: Although only a few people exposed to a traumatic event (TE) develop posttraumatic stress disorder (PTSD), symptoms that do not meet full PTSD criteria are common and often clinically significant. Individuals ...
• Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants

  van der Valk, Ralf J.P.; Cáceres, Alejandro; Sunyer Deu, Jordi; EArly Genetics & Lifecourse Epidemiology (EAGLE) Consortium (Elsevier, 2014)

  BACKGROUND: The fraction of exhaled nitric oxide (Feno) value is a biomarker of eosinophilic airway inflammation and is associated with childhood asthma. Identification of common genetic variants associated with childhood ...
• DSM-5 and ICD-11 definitions of posttraumatic stress disorder: investigating "narrow" and "broad" approaches

  Stein, Dan J.; Alonso Caballero, Jordi; Kessler, Ronald C. (Wiley-VCH Verlag, 2014)

  BACKGROUND: The development of the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and ICD-11 has led to reconsideration of diagnostic criteria for posttraumatic stress disorder (PTSD). The World ...

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