Welcome to the UPF Digital Repository

Articles (Departament de Ciències Experimentals i de la Salut)

Articles (Departament de Ciències Experimentals i de la Salut)

 

Articles de recerca, en accés obert, del Departament de Ciències Experimentals i de la Salut de la UPF.

Recent Submissions

  • Pires Hartwig, Fernando; Dalmau Bueno, Albert; Guxens Junyent, Mònica; Bustamante Pineda, Mariona; Gomes Victora, Cesar (Oxford University Press, 2019)
    Background: Accumulating evidence suggests that breastfeeding benefits children’s intelligence, possibly due to long-chain polyunsaturated fatty acids (LC-PUFAs) present in breast milk. Under a nutritional adequacy hypothesis, ...
  • McCartney, Ann M.; Hyland, Edel M.; Cormican, Paul; Moran, Raymond J.; Webb, Andrew E.; Lee, Kate D.; Hernández Rodríguez, Jéssica, 1983-; Prado Martínez, Javier, 1987-; Creevey, Christopher J.; Aspden, Julie L.; McInerney, James O.; Marquès i Bonet, Tomàs, 1975-; O'Connell, Mary J. (Oxford University Press, 2019)
    Gene fusion occurs when two or more individual genes with independent open reading frames becoming juxtaposed under the same open reading frame creating a new fused gene. A small number of gene fusions described in detail ...
  • Ruiz-Arenas, Carlos; Cáceres, Alejandro; López Sánchez, Marcos, 1986-; Tolosana, Ignacio; Pérez Jurado, Luis Alberto; González Ruiz, Juan Ramón (Public Library of Science (PLoS), 2019)
    Polymorphic inversions contribute to adaptation and phenotypic variation. However, large multi-centric association studies of inversions remain challenging. We present scoreInvHap, a method to genotype inversions from SNP ...
  • Ciruelos, Eva; Alba, Emilio; López, Rafael; Lluch, Ana; Martín, Miguel; Arroyo, Isabel; Navarro, Beatriz; Carcedo, David; Colomer, Ramon; Albanell Mestres, Joan (Impact Journals, 2019)
    Introduction: Trastuzumab has become the standard treatment for both HER2-positive early and metastatic breast cancer (HER2+ eBC or mBC) since its approval. The objective of the study is to estimate the benefit of adjuvant ...
  • Buxeda, Anna; Redondo Pachón, María Dolores; Pérez-Sáez, María José; Bartolomé, Álvaro; Mir Fontana, M. Luisa; Pascual-Dapena, Ana; Sans, Anna; Duran Jordà, Xavier, 1974-; Crespo Barrio, Marta; Pascual Santos, Julio (Impact Journals, 2019)
    Kidney transplant (KT) recipients are at greater risk of developing some cancers than the general population. Moreover, cancer is the only cause of death that is currently increasing after kidney transplantation. We analyzed ...
  • Alioto, Tyler; Cruz, Fernando; Gómez Garrido, Jèssica; Triyatni, Miriam; Gut, Marta; Frias, Leonor; Esteve-Codina, Anna; Menne, Stephan; Kiialainen, Anna; Kumpesa, Nadine; Birzele, Fabian; Schmucki, Roland; Gut, Ivo Glynne; Spleiss, Olivia (Genetics Society of America, 2019)
    The Eastern woodchuck (Marmota monax) has been extensively used in research of chronic hepatitis B and liver cancer because its infection with the woodchuck hepatitis virus closely resembles a human hepatitis B virus ...
  • Mixão, Verónica; Saus Martínez, Ester; Perez Hansen, Antonio; Lass-Florl, Cornelia; Gabaldón Estevan, Juan Antonio, 1973- (Genetics Society of America, 2019)
    Infections caused by opportunistic yeast pathogens have increased over the last years. These infections can be originated by a large number of diverse yeast species of varying incidence, and with distinct clinically relevant ...
  • Pogoda, Michaela; Hilke, Franz-Joachim; Lohmann, Ebba; Sturm, Marc; Lenz, Florian; Matthes, Jakob; Muyas Remolar, Francesc, 1992-; Ossowski, Stephan; Hoischen, Alexander; Faust, Ulrike; Sepahi, Ilnaz; Casadei, Nicolas; Poths, Sven; Riess, Olaf; Schroeder, Christopher; Grundmann, Kathrin (Frontiers, 2019)
    Background: This study's aim was to investigate a large cohort of dystonia patients for pathogenic and rare variants in the ATM gene, making use of a new, cost-efficient enrichment technology for NGS-based screening. ...
  • De Toma, Ilario; Ortega Crespo, Mireia, 1988-; Aloy, Patrick, 1972-; Sabidó Aguadé, Eduard, 1981-; Dierssen, Mara (Frontiers, 2019)
    Down syndrome (DS), caused by trisomy of chromosome 21, is the most common genetic cause of intellectual disability. We recently discovered that green tea extracts containing epigallocatechin-3-gallate (EGCG) improve ...
  • Cebrià i Costa, Joan Pau, 1989-; Pascual-Reguant, Laura; Gonzalez-Perez, Abel; Serra-Bardenys, Gemma; Querol, J.; Cosín, M.; Verde, Gaetano; Cigliano, R. A.; Sanseverino, Walter; Segura-Bayona, Sandra; Iturbide Martínez de Albéniz, Ane, 1989-; Andreu Martínez, David; Nuciforo, Paolo G.; Bernado-Morales, C.; Rodilla, Verónica; Arribas, Joaquín; Yelamos López, Jose; García de Herreros, Antonio; Stracker, Travis; Peiró Sales, Sandra (Nature Research, 2020)
    Oxidation of H3 at lysine 4 (H3K4ox) by lysyl oxidase-like 2 (LOXL2) generates an H3 modification with an unknown physiological function. We find that LOXL2 and H3K4ox are higher in triple-negative breast cancer (TNBC) ...
  • Hardy-Werbin, Max; Rocha, Pedro P.; Arpí Llucià, Oriol; Taus García, Álvaro; Nonell Mazelón, Lara; Duran Jordà, Xavier, 1974-; Villanueva, Xavier; Joseph-Pietras, Deborah; Nolan, Luke; Danson, Sarah; Griffiths, Richard; López-Botet, M. (Miguel); Rovira Guerín, Ana; Albanell Mestres, Joan; Ottensmeier, Christian; Arriola Aperribay, Edurne (Taylor & Francis, 2019)
    Background. Immunotherapy has shown efficacy in small cell lung cancer (SCLC), but only a subset of patients benefits. Surrogate biomarkers are urgently needed. Our aim was to evaluate serum Th1, Th2, and proinflammatory ...
  • Di Stefano, Marco; Di Giovanni, Francesca, 1985-; Pozharskaia, Vasilia; Gomar-Alba, Mercè; Baù, Davide; Carey, Lucas, 1980-; Marti-Renom, Marc A.; Mendoza, Manuel (Mendoza Palomares) (Genetics Society of America, 2020)
    The three-dimensional (3D) organization of chromosomes can influence transcription. However, the frequency and magnitude of these effects remain debated. To determine how changes in chromosome positioning affect transcription ...
  • Pocurull, Miriam; Fullana, Aïda M.; Ferro, Miquel; Valero, Pau; Escudero, Nuria; Saus Martínez, Ester; Gabaldón Estevan, Juan Antonio, 1973-; Sorribas, F. Javier (Frontiers Media, 2020)
    Meloidogyne is the most damaging plant parasitic nematode genus affecting vegetable crops worldwide. The induction of plant defense mechanisms against Meloidogyne in tomato by some Trichoderma spp. strains has been proven ...
  • Kuderna, Lukas F.K.; Solís Moruno, Manuel; Batlle Masó, Laura; Julià, Eva; Lizano, Esther; Anglada Busquets, Roger; Ramírez Bautista, Eva; Bote, Alex; Tormo, Marc; Marquès i Bonet, Tomàs, 1975-; Fornas Carreño, Oscar; Casals López, Ferran (Frontiers Media, 2020)
    Sorting of individual chromosomes by Flow Cytometry (flow-sorting) is an enrichment method to potentially simplify genome assembly by isolating chromosomes from the context of the genome. We have recently developed a ...
  • Nienen, Mikalai; Stervbo, Ulrik; Mölder, Felix; Kaliszczyk, Sviatlana; Kuchenbecker, Leon; Gayova, Ludmila; Schweiger, Brunhilde; Jürchott, Karsten; Hecht, Jochen; Neumann, Avidan U.; Rahmann, Sven; Westhoff, Timm; Reinke, Petra; Thiel, Andreas; Babel, Nina (Frontiers, 2019)
    Influenza vaccination is a common approach to prevent seasonal and pandemic influenza. Pre-existing antibodies against close viral strains might impair antibody formation against previously unseen strains-a process called ...
  • Vitelli Storelli, Facundo; Kogevinas, Manolis; Martín, Vicente (MDPI, 2019)
    Several epidemiological studies have investigated the association between the dietary flavonoid intake and gastric cancer (GC) risk; however, the results remain inconclusive. Investigating the relationship between the ...
  • Li, Zhen; Leynaert, Bénédicte; Dumas, Orianne; Díaz Gil, Oscar; García Aymerich, Judith; Fitó Colomer, Montserrat; Le Moual, Nicole; Pison, Christophe; Romieu, Isabelle; Siroux, Valérie; Camargo, Carlos A.; Varraso, Raphaëlle; Nadif, Rachel (Wiley, 2019)
    Objective: Obesity is a likely risk factor for asthma. However, underlying mechanisms by which obesity affects asthma activity remain poorly understood. This study aimed to investigate the role of leptin, an adipocyte-derived ...
  • Consortium OPATHY; Gabaldón Estevan, Juan Antonio, 1973- (Oxford University Press, 2019)
    The incidence of opportunistic yeast infections in humans has been increasing over recent years. These infections are difficult to treat and diagnose, in part due to the large number and broad diversity of species that can ...
  • Davey, Norman E.; Notredame, Cedric; Tosatto, Silvio C.E. (F1000Research, 2019)
    Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments ...
  • Altena, Eveline; Smeding, Risha; van der Gaag, Kristiaan J.; Larmuseau, Maarten H. D.; Decorte, Ronny; Lao Grueso, Oscar, 1976-; Kayser, Manfred; Kraaijenbrink, Thirsa; de Knijff, Peter (Nature Research, 2020)
    Previous studies indicated existing, albeit limited, genetic-geographic population substructure in the Dutch population based on genome-wide data and a lack of this for mitochondrial SNP based data. Despite the aforementioned ...

View more