Welcome to the UPF Digital Repository

Articles (Departament de Ciències Experimentals i de la Salut)

Articles (Departament de Ciències Experimentals i de la Salut)

 

Articles de recerca, en accés obert, del Departament de Ciències Experimentals i de la Salut de la UPF.

Recent Submissions

  • Gomis González, Maria, 1988-; Galera López, Lorena; Ten-Blanco, Marc; Busquets Garcia, Arnau, 1985-; Cox, Thomas; Maldonado, Rafael, 1961-; Ozaita Mintegui, Andrés, 1969- (Springer, 2020)
    The brain encodes, stores, and retrieves relevant information in the form of memories that are classified as short-term (STM) and long-term memories (LTM) depending on the interval between acquisition and retrieval. It is ...
  • Cabrera-Aguilera, Ignacio; Falcones, Bryan; Calvo-Fernández, Alicia; Benito Villabriga, Begoña; Barreiro Portela, Esther; Gea Guiral, Joaquim; Farré, Ramon; Almendros, Isaac; Farré López, Núria (Public Library of Science (PLoS), 2020)
    Heart failure (HF) impairs diaphragm function. Animal models realistically mimicking HF should feature both the cardiac alterations and the diaphragmatic dysfunction characterizing this disease. The isoproterenol-induced ...
  • Stik, Grégoire; Vidal, Enrique; Barrero, Mercedes; Cuartero, Sergi; Vila-Casadesús, Maria; Mendieta-Esteban, Julen; Tian, Tian V.; Choi, Jinmi; Berenguer, Clara; Abad, Amaya; Borsari, Beatrice; Le Dily, François; Cramer, Patrick; Martí Renom, Marc A.; Stadhouders, Ralph; Graf, T. (Thomas) (Nature Research, 2020)
    Three-dimensional organization of the genome is important for transcriptional regulation1-7. In mammals, CTCF and the cohesin complex create submegabase structures with elevated internal chromatin contact frequencies, ...
  • Encode Project Consortium; Snyder, Michael; Myers, Richard M. (Nature Research, 2020)
    The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated ...
  • Ramilowski, Jordan A.; Borsari, Beatrice; Garrido Martín, Diego, 1992-; Muñoz-Aguirre, Manuel; Nurtdinov, Ramil; Guigó Serra, Roderic; Carninci, Piero (Cold Spring Harbor Laboratory Press (CSHL Press), 2020)
    Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we systematically knocked down the expression ...
  • Encode Project Consortium; Moore, Jill E.; Guigó Serra, Roderic; Weng, Zhiping (Nature Research, 2020)
    The human and mouse genomes contain instructions that specify RNAs and proteins and govern the timing, magnitude, and cellular context of their production. To better delineate these elements, phase III of the Encyclopedia ...
  • Sousa Pinto, Bernardo; Antó, Aram; Czarlewski, Wienia; Antó i Boqué, Josep Maria; Almeida Fonseca, João; Bousquet, Jean (JMIR Publications, 2020)
    Background: The influence of media coverage on web-based searches may hinder the role of Google Trends (GT) in monitoring coronavirus disease (COVID-19). Objective: The aim of this study was to assess whether COVID-19-related ...
  • Torrens Fontanals, Mariona; Stepniewski, Tomasz Maciej, 1988-; Aranda García, David; Morales Pastor, Adrián; Medel Lacruz, Brian; Selent, Jana (MDPI, 2020)
    G protein-coupled receptors (GPCRs) are implicated in nearly every physiological process in the human body and therefore represent an important drug targeting class. Advances in X-ray crystallography and cryo-electron ...
  • Breschi, Alessandra, 1988-; Muñoz-Aguirre, Manuel; Wucher, Valentin; Davis, Carrie A.; Garrido Martín, Diego, 1992-; Djebali, Sarah; Gillis, Jesse; Pervouchine, Dmitri D.; Vlasova, Anna; Dobin, Alexander; Zaleski, Chris; Drenkow, Jorg; Danyko, Cassidy; Scavelli, Alexandra; Reverter, Ferran; Snyder, Michael; Gingeras, Thomas R.; Guigó Serra, Roderic (Cold Spring Harbor Laboratory Press (CSHL Press), 2020)
    We have produced RNA sequencing data for 53 primary cells from different locations in the human body. The clustering of these primary cells reveals that most cells in the human body share a few broad transcriptional programs, ...
  • Karyotaki, Eirini; Cuijpers, Pim; Albor, Yesica; Alonso Caballero, Jordi; Auerbach, Randy P.; Bantjes, Jason; Bruffaerts, Ronny; Ebert, David Daniel; Hasking, Penelope; Kiekens, Glenn; Lee, Sue; McLafferty, Margaret; Mak, Arthur; Mortier, Philippe; Sampson, Nancy A.; Stein, Dan J.; Vilagut Saiz, Gemma, 1975-; Kessler, Ronald C.; WHO World Mental Health Survey Collaborators (Frontiers, 2020)
    The college years are stressful for many students. Identifying the sources of stress and their relative importance in leading to clinically significant emotional problems may assist in the development of targeted stress ...
  • McGrath, John J.; Alonso Caballero, Jordi; de Jonge, P. (Cambridge University Press, 2020)
    Aims: Epidemiological studies indicate that individuals with one type of mental disorder have an increased risk of subsequently developing other types of mental disorders. This study aimed to undertake a comprehensive ...
  • De Koninck, Magali; Lapi, Eleonora; Badía Careaga, Claudio; Cossío, Itziar; Giménez-Llorente, Daniel; Rodríguez-Corsino, Miriam; Andrada, Elena; Hidalgo, Andrés; Manzanares, Miguel; Real, Francisco X.; Losada, Ana (Elsevier, 2020)
    Cohesin mediates sister chromatid cohesion and 3D genome folding. Two versions of the complex carrying STAG1 or STAG2 coexist in somatic vertebrate cells. STAG2 is commonly mutated in cancer, and germline mutations have ...
  • Jiménez, Javier; Queralt Badia, Ethel; Posas Garriga, Francesc; Nadal Clanchet, Eulàlia de (Taylor & Francis, 2020)
    During evolution, cells have developed a plethora of mechanisms to optimize survival in a changing and unpredictable environment. In this regard, they have evolved networks that include environmental sensors, signaling ...
  • Hruschka, Natascha; Andreu Martínez, David; Real, Francisco X.; Martinelli, Paola (Nature Research, 2020)
    As the catalog of oncogenic driver mutations is expanding, it becomes clear that alterations in a given gene might have different functions and should not be lumped into one class. The transcription factor GATA3 is a ...
  • García-Fernández, Carla; Font-Porterias, Neus; Kučinskas, Vaidutis; Sukarova-Stefanovska, Emilija; Pamjav, Horolma; Makukh, Halyna; Dobón Berenguer, Begoña, 1987-; Bertranpetit, Jaume, 1952-; Netea, Mihai G; Calafell i Majó, Francesc; Comas, David, 1969- (Nature Research, 2020)
    The Roma population is a European ethnic minority characterized by recent and multiple dispersals and founder effects. After their origin in South Asia around 1,500 years ago, they migrated West. In Europe, they diverged ...
  • Nye, Jessica, 1986-; Mondal, Mayukh, 1989-; Bertranpetit, Jaume, 1952-; Laayouni, Hafid, 1968- (Oxford University Press, 2020)
    After diverging, each chimpanzee subspecies has been the target of unique selective pressures. Here, we employ a machine learning approach to classify regions as under positive selection or neutrality genome-wide. The ...
  • González Hernández, Sara; Gómez, Manuel J.; Sánchez Cabo, Fátima; Méndez Ferrer, Simón; Muñoz Cánoves, Pura, 1962-; Isern, Joan (American Hearth Association, 2020)
    Rationale: The molecular mechanisms underlying the formation of coronary arteries during development and during cardiac neovascularization after injury are poorly understood. However, a detailed description of the relevant ...
  • Tang, Jun; Ramis Cabrer, Daniel, 1993-; Curull Serrano, Víctor; Wang, Xuejie; Qin, Liyun; Mateu Jiménez, Mercè, 1990-; Duran Jordà, Xavier, 1974-; Pijuan Andujar, Lara; Rodríguez-Fuster, Alberto; Aguiló Espases, Rafael; Barreiro Portela, Esther (MDPI, 2020)
    Background: The immune microenvironment plays a role in tumorigenesis. Chronic Obstructive Pulmonary Disease (COPD) is an independent risk factor for lung cancer (LC). We hypothesized that immune profile characterized by ...
  • González-Alonso, Paula; Arpí Llucià, Oriol; Rovira Guerín, Ana; Albanell Mestres, Joan; Rojo, Federico (MDPI, 2020)
    Trastuzumab is the first-line targeted therapeutic drug for HER2-positive breast cancer, leading to improved overall survival. However, acquired resistance inevitably occurs. We aimed to identify, quantify, and assess the ...
  • Silva Peñaherrera, Michael; López Ruiz, María, 1982-; Merino Salazar, Pamela Alexandra, 1978-; Gómez García, Antonio Ramón; Benavides, Fernando G. (Fernando García) (BioMed Central, 2020)
    Background: Latin America and the Caribbean (LAC) is the world's most inequitable region in terms of wealth distribution. The full scale of social inequalities in health has been hidden by the lack of reliable data. This ...

View more