• Environmental temperatures shape thermal physiology as well as diversification and genome-wide substitution rates in lizards

  Garcia Porta, Joan; Carranza Gil-Dolz del Castellar, Salvador; Wollenberg Valero, Katharina C. (Nature Research, 2019)

  Climatic conditions changing over time and space shape the evolution of organisms at multiple levels, including temperate lizards in the family Lacertidae. Here we reconstruct a dated phylogenetic tree of 262 lacertid ...
• rs12416605:C>T in MIR938 associates with gastric cancer through affecting the regulation of the CXCL12 chemokine gene

  Torruella Loran, Ignasi, 1987-; Ramirez Viña, María Karla; Zapata Contreras, Daniela; Muñoz, Xavier; Garcia Ramallo, Eva; Bonet, Catalina; Gonzalez, Carlos A.; Sala, Núria; Espinosa Parrilla, Yolanda, 1971-; EPIC gastric cancer working group (Wiley, 2019)

  Background: MicroRNAs are small regulatory RNAs with important roles in carcinogenesis. Genetic variants in these regulatory molecules may contribute to disease. We aim to identify allelic variants in microRNAs as ...
• A unique cluster of roo insertions in the promoter region of a stress response gene in Drosophila melanogaster

  Merenciano, Miriam; Iacometti, Camillo; González, Josefa (BioMed Central, 2019)

  Transposable elements (TEs) are not randomly distributed in the genome. A genome-wide analysis of the D. melanogaster genome found that differences in TE density across 50 kb genomic regions was due both to transposition ...
• A benchmark of transposon insertion detection tools using real data

  Vendrell Mir, Pol; Barteri, Fabio; Merenciano, Miriam; González, Josefa; Casacuberta, Josep M.; Castanera, Raúl (BioMed Central, 2019)

  Background: Transposable elements (TEs) are an important source of genomic variability in eukaryotic genomes. Their activity impacts genome architecture and gene expression and can lead to drastic phenotypic changes. ...
• Genetic affinities of an eradicated European Plasmodium falciparum strain

  de Dios, Toni; van Dorp, Lucy; Gelabert Xirinachs, Pere, 1991-; Carøe, Christian; Sandoval Velasco, Marcela; Fregel, Rosa; Escosa, Raül; Aranda, Carles; Huijben, Silvie; Balloux, François; Gilbert, M Thomas; Lalueza Fox, Carles, 1965- (UNLISTED PUBLISHER, 2019)

  Malaria was present in most of Europe until the second half of the 20th century, when it was eradicated through a combination of increased surveillance and mosquito control strategies, together with cross-border and political ...
• Use of health apps by nurses for professional purposes: web-based survey study

  Mayer, Miguel Ángel, 1960-; Rodríguez Blanco, Octavi; Torrejon, Antonio (JMIR Publications Inc., 2019)

  Background: In the last few years, the number of mobile apps for health professionals has increased exponentially. Nevertheless, there is a lack of knowledge about the professional use, training requirements, and quality ...
• Association of occupational exposure to disinfectants with incidence of chronic obstructive pulmonary disease among US female nurses

  Dumas, Orianne; Varraso, Raphaëlle; Boggs, Krislyn M.; Quinot, Catherine; Zock, Jan-Paul; Henneberger, Paul K.; Speizer, Frank E.; Le Moual, Nicole; Camargo, Carlos A. (American Medical Association, 2019)

  Importance: Exposure to disinfectants in health care workers has been associated with respiratory health outcomes, including asthma. Despite the biological plausibility of an association between disinfectants (irritant ...
• Density of green spaces and cardiovascular risk factors in the city of Madrid: the heart healthy hoods study

  Plans, Elena; Gullón, Pedro; Cebrecos, Alba; Fontán, Mario; Díez, Julia; Nieuwenhuijsen, Mark J.; Franco, Manuel (MDPI, 2019)

  The aim of this study is to evaluate the relationship between the density of green spaces at different buffer sizes (300, 500, 1000 and 1500 m) and cardiovascular risk factors (obesity, hypertension, high cholesterol, and ...
• Is being employed always better for mental wellbeing than being unemployed? Exploring the role of gender and welfare state regimes during the economic crisis

  Cortès-Franch, Imma; Puig Barrachina, Vanessa; Vargas Leguás, Hernán; Arcas, M. Marta; Artazcoz Lazcano, Lucía, 1963- (MDPI, 2019)

  The growth of poor jobs related to economic crisis adds to its increase since the mid-1970s as a result of new forms of flexible employment. In Europe, there is no clear evidence on whether working in a poor-quality job ...
• Functions and dysfunctions of nitric oxide in brain

  Picón-Pagès, Pol; Garcia Buendia, Joan; Muñoz López, Francisco José, 1964- (Elsevier, 2019)

  Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood flow and also has important roles in intracellular signaling in neurons from the regulation of the neuronal metabolic status to ...
• Beer phenolic composition of simple phenols, prenylated flavonoids and alkylresorcinols

  Boronat Rigol, Anna, 1990-; Soldevila-Domenech, Natalia; Rodríguez-Morató, Jose, 1987-; Martínez-Huélamo, Miriam; Lamuela-Raventós, Rosa M.; Torre Fornell, Rafael de la (MDPI, 2020)

  Beer is a fermented beverage with beneficial phenolic compounds and is widely consumed worldwide. The current study aimed to describe the content of three families of phenolic compounds with relevant biological activities: ...
• Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans

  Boronat Rigol, Anna, 1990-; Mateus Rodriguez, Julian Andrés; Soldevila-Domenech, Natalia; Guerra Albà, Mercè; Rodríguez-Morató, Jose, 1987-; Varon, Carlota; Muñoz, Daniel; Barbosa, Francina; Morales, Juan Carlos; Gaedigk, Andreas; Langohr, Klaus; Covas Planells, Maria Isabel; Pérez Mañá, Clara; Fitó Colomer, Montserrat; Tyndale, Rachel F.; Torre Fornell, Rafael de la (Elsevier, 2019)

  Here we present new and original data on the endogenous conversion of tyrosol (Tyr) into hydroxytyrosol (OHTyr) in humans and its effects on the cardiovascular system. A randomized, crossover, controlled clinical trial was ...
• Thromboembolic, cardiovascular and overall mortality risks of aromatase inhibitors, compared with tamoxifen treatment: an outpatient-register-based retrospective cohort study

  Pineda-Moncusí, Marta; Garcia Giralt, Natàlia; Díez Pérez, Adolfo; Tusquets Trias de Bes, Ignacio; Servitja Tormo, Sonia; Albanell Mestres, Joan; Prieto-Alhambra, Daniel; Nogués Solan, Francesc Xavier (SAGE Publications, 2020)

  Background: Tamoxifen (TAM) and aromatase inhibitor (AI) therapies have been associated with increased risk of thromboembolic and cardiovascular events, respectively, in addition to other side effects. This study analysed ...
• Evolutionary and functional patterns of shared gene neighbourhood in fungi

  Marcet Houben, Marina; Gabaldón Estevan, Juan Antonio, 1973- (Nature Research, 2019)

  Gene clusters comprise genomically co-localized and potentially co-regulated genes that tend to be conserved across species. In eukaryotes, multiple examples of metabolic gene clusters are known, particularly among fungi ...
• Impact of a telemedicine program on the reduction in the emission of atmospheric pollutants and journeys by road

  Vidal Alaball, Josep; Franch Parella, Jordi; López Seguí, Francesc; Garcia Cuyàs, Francesc; Mendioroz Peña, Jacobo (MDPI, 2019)

  This retrospective study evaluates the effect of a telemedicine program developed in the central Catalan region in lowering the environmental footprint by reducing the emission of atmospheric pollutants, thanks to a reduction ...
• Influence of childhood asthma and allergies on occupational exposure in early adulthood: a prospective cohort study

  Dumas, Orianne; Le Moual, Nicole; Lowe, Adrian J.; Lodge, Caroline J.; Zock, Jan-Paul; Kromhout, Hans; Erbas, Bircan; Perret, Jennifer L.; Dharmage, Shyamali C.; Benke, Geza; Abramson, Michael J. (MDPI, 2019)

  We aimed to determine whether history of asthma/allergies in childhood was associated with avoidance of jobs with exposure to asthmagens in early adulthood. The Melbourne Atopic Cohort Study recruited 620 children at high ...
• Oral health-related quality of life in native and immigrant populations in the PELFI study in Spain

  Agudelo Suárez, Andrés A; Vivares Builes, Annie M.; Muñoz Pino, Natalia; Martínez Martínez, José Miguel, 1974-; Reid, Alison; Ronda-Pérez, Elena (MDPI, 2019)

  Quality of life and its relationship to oral health is an important consideration in the determinants of health of vulnerable groups. The aim of this study is to assess oral health-related quality of life (OHRQoL) and its ...
• Population health inequalities across and within european metropolitan areas through the lens of the EURO-HEALTHY Population Health Index

  Costa, Claudia; Santana, Paula; Dimitroulopoulou, Sani; Burström, Bo; Borrell i Thió, Carme; Schweikart, Jürgen; Dzúrová, Dagmar; Zangarini, Nicolás; Katsouyanni, Klea; Deboseree, Patrick; Freitas, Ângela; Mitsakou, Christina; Samoli, Evangelia; Vardoulakis, Sotiris; Marí Dell'Olmo, Marc, 1978-; Gotsens Miquel, Mercè, 1983-; Lustigova, Michala; Corman, Diana; Costa, Giuseppe (MDPI, 2019)

  The different geographical contexts seen in European metropolitan areas are reflected in the uneven distribution of health risk factors for the population. Accumulating evidence on multiple health determinants point to the ...
• Self-reported sleep disturbance from road, rail and aircraft noise: exposure-response relationships and effect modifiers in the SiRENE study

  Brink, Mark; Schäffer, Beat; Vienneau, Danielle; Pieren, Reto; Foraster Pulido, Maria, 1984-; Eze, Ikenna C.; Rudzik, Franziska; Thiesse, Laurie; Cajochen, Christian; Probst-Hensch, Nicole; Röösli, Martin; Wunderli, Jean Marc (MDPI, 2019)

  This survey investigates the cross-sectional association between nighttime road, rail and aircraft noise exposure and the probability to be highly sleep disturbed (%HSD), as measured by self-report in postal and online ...
• DNA methylation in inflammatory pathways modifies the association between BMI and adult-onset non-atopic asthma

  Jeong, Ayoung; Imboden, Medea; Ghantous, Akram; Novoloaca, Alexei; Carsin, Anne-Elie; Kogevinas, Manolis; Schindler, Christian; Lovison, Gianfranco; Herceg, Zdenko; Cuenin, Cyrille; Vermeulen, Roel; Jarvis, Deborah; Amaral, André F.S.; Kronenberg, Florian; Vineis, Paolo; Probst-Hensch, Nicole (MDPI, 2019)

  A high body mass (BMI) index has repeatedly been associated with non-atopic asthma, but the biological mechanism linking obesity to asthma is still poorly understood. We aimed to test the hypothesis that inflammation and/or ...

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