Browsing Departament de Medicina i Ciències de la Vida by Author "Maier, Michael, 1983-"

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Budding yeast complete DNA synthesis after chromosome segregation begins

Ivanova, Tsvetomira Georgieva, 1978-; Maier, Michael, 1983-; Missarova, Alsu, 1990-; Ziegler-Birling, Céline; Dam, Monica; Gomar-Alba, Mercè; Carey, Lucas, 1980-; Mendoza, Manuel (Mendoza Palomares) (Nature Research, 2020)

To faithfully transmit genetic information, cells must replicate their entire genome before division. This is thought to be ensured by the temporal separation of replication and chromosome segregation. Here we show that ...
The Aurora-B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress

Amaral, Nuno, 1984-; Vendrell Arasa, Alexandre; Funaya, Charlotta; Idrissi, Fatima-Zahra; Maier, Michael, 1983-; Kumar, Arun; Neurohr, Gabriel Erich; Colomina, Neus; Torres Rosell, Jordi; Geli, María-Isabel; Mendoza, Manuel (Mendoza Palomares) (Nature Publishing Group, 2016)

Anaphase chromatin bridges can lead to chromosome breakage if not properly resolved before completion of cytokinesis. The NoCut checkpoint, which depends on Aurora B at the spindle midzone, delays abscission in response ...

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