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Browsing Departament de Medicina i Ciències de la Vida by Title

Browsing Departament de Medicina i Ciències de la Vida by Title

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  • Oral health-related quality of life in native and immigrant populations in the PELFI study in Spain
    Agudelo Suárez, Andrés A; Vivares Builes, Annie M.; Muñoz Pino, Natalia; Martínez Martínez, José Miguel, 1974-; Reid, Alison; Ronda-Pérez, Elena (MDPI, 2019)
    Quality of life and its relationship to oral health is an important consideration in the determinants of health of vulnerable groups. The aim of this study is to assess oral health-related quality of life (OHRQoL) and its ...
  • Orally active peptide vector allows using cannabis to fight pain while avoiding side effects
    Gallo, María, 1989-; Moreno, Estefanía; Defaus, Sira; Ortega Alvaro, Antonio; Gonzalez, Angel; Robledo, Patricia, 1958-; Cavaco, Marco; Neves, Vera; Castanho, Miguel A.R.B.; Casadó, Vicent; Pardo Carrasco, Leonardo; Maldonado, Rafael, 1961-; Andreu Martínez, David (American Chemical Society (ACS), 2021)
    The activation of cannabinoid CB1 receptors (CB1R) by Δ9-tetrahydrocannabinol (THC), the main component of Cannabis sativa, induces analgesia. CB1R activation, however, also causes cognitive impairment via the serotonin ...
  • Orchestrating privacy-protected big data analyses of data from different resources with R and DataSHIELD
    Marcon, Yannick; Bishop, Tom; Avraam, Demetris; Escriba-Montagut, Xavier; Ryser-Welch, Patricia; Wheater, Stuart; Burton, Paul; González, Juan Ramón (Public Library of Science (PLoS), 2021)
    Combined analysis of multiple, large datasets is a common objective in the health- and biosciences. Existing methods tend to require researchers to physically bring data together in one place or follow an analysis plan and ...
  • Orexins and fear: implications for the treatment of anxiety disorders
    Flores de los Heros, África, 1985-; Saravia Santos, Rocio, 1988-; Maldonado, Rafael, 1961-; Berrendero Díaz, Fernando, 1971- (Elsevier, 2015)
    An understanding of the neurobiological mechanisms involved in the regulation of fear is essential for the development of new treatments for anxiety disorders, such as phobias, panic, and post-traumatic stress disorders ...
  • Organophosphate pesticide metabolite concentrations in urine during pregnancy and offspring attention-deficit hyperactivity disorder and autistic traits
    van den Dries, Michiel; Guxens Junyent, Mònica; Pronk, Anjoeka; Spaan, Suzanne; El Marroun, Hanan; Jusko, Todd A.; Longnecker, Matthew P.; Ferguson, Kelly K.; Tiemeier, Henning (Elsevier, 2019)
    Background: Prenatal exposure to organophosphate (OP) pesticides has been associated with altered neuronal cell development and behavioral changes in animal offspring. However, the few studies investigating the association ...
  • Organophosphate pesticide metabolite concentrations in urine during pregnancy and offspring nonverbal IQ at age 6 years
    Jusko, Todd A.; van den Dries, Michiel; Pronk, Anjoeka; Shaw, Pamela A.; Guxens Junyent, Mònica; Spaan, Suzanne; Jaddoe, Vincent W. V.; Tiemeier, Henning; Longnecker, Matthew P. (National Institute of Environmental Health Sciences (NIEHS), 2019)
    Background: Susceptibility to organophosphate (OP) pesticide neurotoxicity may be greatest during the prenatal period; however, previous studies have produced mixed findings concerning in utero OP pesticide exposure and ...
  • Origin and evolution of eukaryotic transcription factors
    de Mendoza, Alex; Sebé-Pedrós, Arnau (Elsevier, 2019)
    Transcription factors (TFs) have a central role in genome regulation directing gene transcription through binding specific DNA sequences. Eukaryotic genomes encode a large diversity of TF classes, each defined by unique ...
  • Origin and evolution of metabolic sub-cellular compartmentalization in eukaryotes
    Gabaldón Estevan, Juan Antonio, 1973-; Pittis, Alexandros, 1982- (Elsevier, 2016)
    A high level of subcellular compartmentalization is a hallmark of eukaryotic cells. This intricate internal organization was present already in the common ancestor of all extant eukaryotes, and the determination of the ...
  • Origin and genetic differentiation of Three Mexican Native Groups (Purépechas, Triquis and Mayas): contribution of CODIS-STRs to the history of human populations of Mesoamerica
    Martínez Cortés, G.; Nuño Arana, I.; Rubi Castellanos, R.; Vilchis Dorantes, G.; Luna Vázquez, A.; Coral Vázquez, R. M.; Canto Cetina, T.; Salazar Flores, J.; Muñoz Valle, J. F.; Sandoval Mendoza, Karla; López, Z.; Gamero Lucas, J. J.; Rangel Villalobos, H. (Informa Healthcare, 2010)
    BACKGROUND: CODIS-STRs in Native Mexican groups have rarely been analysed for human identification and anthropological purposes. AIM:/nTo analyse the genetic relationships and population structure among three Native Mexican ...
  • Origin of exon skipping-rich transcriptomes in animals driven by evolution of gene architecture
    Grau Bové, Xavier; Ruiz Trillo, Iñaki; Irimia Martínez, Manuel (BioMed Central, 2018)
    Background: Alternative splicing, particularly through intron retention and exon skipping, is a major layer of pre-translational regulation in eukaryotes. While intron retention is believed to be the most prevalent mode ...
  • Origins of de novo genes in human and chimpanzee
    Ruiz Orera, Jorge, 1988-; Hernández Rodríguez, Jéssica, 1983-; Chiva, Cristina; Sabidó Aguadé, Eduard, 1981-; Kondova, Ivanela; Bontrop, Ronald E.; Marquès i Bonet, Tomàs, 1975-; Albà Soler, Mar (Public Library of Science, 2015)
    The birth of new genes is an important motor of evolutionary innovation. Whereas many new genes arise by gene duplication, others originate at genomic regions that did not contain any genes or gene copies. Some of these ...
  • Orthology clusters from gene trees with possvm
    Grau Bové, Xavier; Sebé-Pedrós, Arnau (Oxford University Press, 2021)
    Possvm (Phylogenetic Ortholog Sorting with Species oVerlap and MCL [Markov clustering algorithm]) is a tool that automates the process of identifying clusters of orthologous genes from precomputed phylogenetic trees and ...
  • Orthopedic surgeons' perspectives on the decision-making process for the use of bioprinter cartilage grafts: web-based survey
    Salvador Verges, Àngels; Fernández Luque, Luis; López Seguí, Francesc, 1991-; Yildirim, Meltem; Salvador i Mata, Bertran; García Cuyàs, Francesc (JMIR Publications, 2019)
    Background: Traumatic and degenerative lesions in the cartilage are one of the most difficult and frustrating types of injuries for orthopedic surgeons and patients. Future developments in medical science, regenerative ...
  • OSIRISv1.2: a named entity recognition system for sequence variants of genes in biomedical literature
    Furlong, Laura I., 1971-; Dach, Holger; Hofmann Apitius, Martin; Sanz, Ferran (BioMed Central, 2008)
    Background: Single Nucleotide Polymorphisms, among other type of sequence variants, constitute key elements in genetic epidemiology and pharmacogenomics. While sequence data about genetic variation is found at databases ...
  • Osmostress-induced gene expression--a model to understand how stress-activated protein kinases (SAPKs) regulate transcription
    Nadal Clanchet, Eulàlia de; Posas Garriga, Francesc (Wiley, 2015)
    Adaptation is essential for maximizing cell survival and for cell fitness in response to sudden changes in the environment. Several aspects of cell physiology change during adaptation. Major changes in gene expression are ...
  • Osteoarticular cryptococcosis successfully treated with high-dose liposomal amphotericin B followed by oral fluconazole
    Deus, Guillem; Gómez-Zorrilla, Silvia; Echeverría Esnal, Daniel; Siverio-Parès, Ana; Güerri Fernández, Roberto; Ares, Jesús; Campillo Ambrós, Núria; Letang Jiménez de Anta, Emilio Ángel; Knobel Freud, Hernando; Grau Cerrato, Santiago; Horcajada Gallego, Juan Pablo (Dove Medical Press, 2021)
    Background: Skeletal involvement of Cryptococcus neoformans is infrequent and usually associated with disseminated cryptococcosis or underlying predisposing conditions. We present an atypical case of osteoarticular ...
  • Otx2 is a target of N-myc and acts as a suppressor of sensory development in the mammalian cochlea
    Vendrell, Víctor; López Hernández, Iris; Durán Alonso, Beatriz; Feijoo Redondo, Ana; Abelló Sumpsi, Gina, 1980-; Gálvez García, Héctor, 1989-; Giráldez, Fernando; Lamonerie, Thomas; Schimmang, Thomas (Company of Biologists, 2015)
    Transcriptional regulatory networks are essential during the formation and differentiation of organs. The transcription factor N-myc is required for proper morphogenesis of the cochlea and to control correct patterning of ...
  • Our lives in boxes: perceived community mediators between housing insecurity and health using a PHOTOVOICE approach
    Vásquez-Vera, Hugo, 1982-; Fernández, Ana; Novoa Pardo, Ana María; Delgado, Lucía; Barcala, Joaquín; Macías, Carlos; Borrell i Thió, Carme; Photovoice Working Group of Public Health Agency of Barcelona (BioMed Central, 2019)
    Background: While the negative effects of housing insecurity on health are well known, the mechanisms and mediators of these effects have been less well studied. The aim of this study is to identify perceived mediators ...
  • Outcomes and molecular profile of oligomonocytic CMML support its consideration as the first stage in the CMML continuum
    Calvo González, Xavier; Roman-Bravo, David; García Gisbert, Nieves, 1994-; Rodriguez-Sevilla, Juan José; García-Avila, Sara; Florensa Brichs, Lourdes; Gibert Fernandez, Joan 1988-; Fernández Rodríguez, M. Concepción; Salido Galeote, Marta; Puiggros Metje, Anna Maria; Espinet Solà, Blanca; Colomo Saperas, Luis Alberto; Bellosillo Paricio, Beatriz; Ferrer, Ana; Arenillas Rocha, Leonor (American Society of Hematology, 2022)
    atients with oligomonocytic chronic myelomonocytic leukemia (OM-CMML) are currently classified according to the 2017 World Health Organization myelodysplastic syndromes classification. However, recent data support considering ...
  • Outdoor air pollution and risk of incident adult haematologic cancer subtypes in a large US prospective cohort
    Diver, W. Ryan; Teras, Lauren R.; Deubler, Emily L.; Turner, Michelle C. (Nature Research, 2024)
    Background: Outdoor air pollution and particulate matter (PM) are classified as Group 1 human carcinogens for lung cancer. Pollutant associations with haematologic cancers are suggestive, but these cancers are aetiologically ...

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