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Browsing Dades primàries de recerca by Author "López Bigas, Núria"

Browsing Dades primàries de recerca by Author "López Bigas, Núria"

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  • Barneda Zahonero, Bruna; Román González, Lidia; Collazo, Olga; Rafati, Haleh; Islam, Abul, 1978-; Bussmann, Lars; Di Tullio, Alessandro, 1982-; Andrés, Luisa De; Graf, T. (Thomas); López Bigas, Núria; Mahmoudi, Tokameh; Parra, Maribel (Universitat Pompeu Fabra, 2013-05)
    HDAC7 is a repressor of myeloid genes whose downregulation in pre-B cells is required for transdifferentiation into macrophages.
  • Tamborero Noguera, David; Rubio Pérez, Carlota; Déu Pons, Jordi; Schroeder, Michael Philipp, 1986-; Vivancos Prellezo, Ana; Rovira Guerín, Ana; Tusquets, Ignasi; Albanell Mestres, Joan; Rodon, Jordi; Tabernero Cartula, Josep; Dienstmann, Rodrigo; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2016-10-17)
    The cancer bioMarkers database is curated and maintained by several clinical and scientific experts in the field of precision oncology supported by the European Union’s Horizon 2020 funding. This database is currently being ...
  • Furney, Simon J.; Madden, Stephen F.; Kisiel, Tomasz A.; Higgins, Desmond G.; López Bigas, Núria (Universitat Pompeu Fabra, 2007-12)
    Cancer gene properties.
  • López Bigas, Núria; De, Subhajyoti; Teichmann, Sarah A. (Universitat Pompeu Fabra, 2007-10)
    Mutations, genes and pathways involved in tumorigenesis across 4,623 cancer genomes/exomes from 13 cancer sites. IntOGen-mutations identifies cancer drivers across tumor types. Nature Methods 10, 2013, doi:10.1038/nmeth.2642
  • Shikhagaie, Medya; López Bigas, Núria (Universitat Pompeu Fabra, 2007-10)
    Web tool for the selection of SNPs from the STAR project with potential functional effect.
  • Pérez Llamas, Christian, 1976-; López Bigas, Núria; Schroeder, Michael Philipp, 1986-; Déu Pons, Jordi (Universitat Pompeu Fabra, 2016-07-05)
    Gitools is a framework for analysis and visualization of multidimensional genomic data using interactive heat-maps
  • Furney, Simon J.; Albà Soler, Mar; López Bigas, Núria (Universitat Pompeu Fabra, 2006-07)
    Database of human genes prioritized for their probability of involvement in dominant or recessive hereditary diseases.
  • Gundem, Gunes; Pérez Llamas, Christian, 1976-; Jené i Sanz, Alba, 1984-; Kedzierska, Anna; Islam, Abul, 1978-; Déu Pons, Jordi; Furney, Simon J.; López Bigas, Núria (Universitat Pompeu Fabra, 2010-02)
    Genes and pathways affected by expression and copy number changes in tumors across projects and cancer types.
  • González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Déu Pons, Jordi; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Jené i Sanz, Alba, 1984-; Santos, Alberto; López Bigas, Núria (Universitat Pompeu Fabra, 2013-05)
    Mutations, genes and pathways involved in tumorigenesis across 4,623 cancer genomes/exomes from 13 cancer sites. IntOGen-mutations identifies cancer drivers across tumor types. Nature Methods 10, 2013, doi:10.1038/nmeth.2642
  • Rubio Pérez, Carlota; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Antolín Hernández, Albert, 1984-; Déu Pons, Jordi; Pérez Llamas, Christian, 1976-; Mestres i López, Jordi; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-03)
    This database contains data on the interactions with therapeutic agents an driver genes contained in Cancer Drivers Database (2014.12). It characterizes the interacting therapeutic agents in terms of clinical phase and ...
  • Rubio Pérez, Carlota; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Antolín Hernández, Albert, 1984-; Déu Pons, Jordi; Pérez Llamas, Christian, 1976-; Mestres i López, Jordi; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-03)
    This database contains information on the genes identified as drivers in Rubio-Perez and Tamborero et al. (2015). It contains information on driver identification at mutational, CNA and gene fusion level. Additional ancillary ...
  • Tamborero Noguera, David; Rubio Pérez, Carlota; Déu Pons, Jordi; Schroeder, Michael Philipp, 1986-; Vivancos Prellezo, Ana; Rovira Guerín, Ana; Tusquets, Ignasi; Albanell Mestres, Joan; Tabernero Cartula, Josep; Dienstman, Rodrigo; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2016-10)
    This database contains the results of the driver analysis performed by the Cancer Genome Interpreter across 6,792 exomes of a pan-cancer cohort of 28 tumor types. Validated oncogenic mutations are identified according to ...
  • González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Jené i Sanz, Alba, 1984-; Santos, Alberto; López Bigas, Núria; Déu Pons, Jordi (Universitat Pompeu Fabra, 2016-07-18)
    Analyses somatic mutations in thousands of tumor genomes to identify cancer driver genes.
  • Tamborero Noguera, David; González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Déu Pons, Jordi; Kandoth, Cyriac; Reimand, Jüri; Lawrence, Michael S.; Getz, Gad; Bader, Gary D.; Ding, Li; López Bigas, Núria (Universitat Pompeu Fabra, 2013-10)
    This file lists the High Confidence Drivers identified as part of the pan-cancer12 initiative, published in the paper Comprehensive identification of mutational cancer driver genes across 12 tumor types" Scientific Reports ...
  • Déu Pons, Jordi; Schroeder, Michael Philipp, 1986-; López Bigas, Núria (Universitat Pompeu Fabra, 2014-03)
    Javascript library to create interactive heatmaps within webpages.
  • Tamborero Noguera, David; López Bigas, Núria; González-Pérez, Abel (Universitat Pompeu Fabra, 2013-02)
    Oncodrive-CIS is a method aimed to identify those copy number alterations (CNAs) leading to larger in cis expression changes that may be useful in elucidating the role of these aberrations in cancer. This is based on the ...
  • Tamborero Noguera, David; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-11)
    OncodriveCLUST is a method aimed to identify genes whose mutations are biased towards a large spatial clustering. This method is designed to exploit the feature that mutations in cancer genes, especially oncogenes, often ...
  • González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-10)
    OncodriveFM detects candidate cancer driver genes and pathways from catalogs of somatic mutations in a cohort of tumors by computing the bias towards the accumulation of functional mutations (FM bias).This novel approach ...
  • Mularoni, Loris; Sabarinathan, Radhakrishnan; González-Pérez, Abel; López Bigas, Núria; Déu Pons, Jordi (Universitat Pompeu Fabra, 2016-06-06)
    Method to identify genomic regions, both coding and non-coding, bearing mutations with significant shift towards high functional impact across a cohort of tumos (FMbias), which are candidates to function as cancer drivers, ...
  • Tamborero Noguera, David; Rubio Pérez, Carlota; Déu Pons, Jordi; Schroeder, Michael Philipp, 1986-; Vivancos Prellezo, Ana; Rovira Guerín, Ana; Tusquets, Ignasi; Albanell Mestres, Joan; Rodon, Jordi; Tabernero Cartula, Josep; Dienstman, Rodrigo; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2016-01)
    Bioinformatics method to identify individual driver mutations.

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