Dades primàries de recerca

Enviaments recents

  • Furney, Simon J.; Albà Soler, Mar; López Bigas, Núria (Universitat Pompeu Fabra, 2006-07)
    Database of human genes prioritized for their probability of involvement in dominant or recessive hereditary diseases.
  • López Bigas, Núria; De, Subhajyoti; Teichmann, Sarah A. (Universitat Pompeu Fabra, 2007-10)
    Mutations, genes and pathways involved in tumorigenesis across 4,623 cancer genomes/exomes from 13 cancer sites. IntOGen-mutations identifies cancer drivers across tumor types. Nature Methods 10, 2013, doi:10.1038/nmeth.2642
  • Shikhagaie, Medya; López Bigas, Núria (Universitat Pompeu Fabra, 2007-10)
    Web tool for the selection of SNPs from the STAR project with potential functional effect.
  • Furney, Simon J.; Madden, Stephen F.; Kisiel, Tomasz A.; Higgins, Desmond G.; López Bigas, Núria (Universitat Pompeu Fabra, 2007-12)
    Cancer gene properties.
  • López Bigas, Núria; Kisiel, Tomasz A.; DeWaal, Dannielle C.; Holmes, Katherine B.; Volkert, Tom L.; Gupta, Sumeet; Love, Jennifer; Murray, Heather L.; Young, Richard A.; Benevolenskaya, Elizaveta V. (Universitat Pompeu Fabra, 2008-09)
    Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation.
  • Gundem, Gunes; Pérez Llamas, Christian, 1976-; Jené i Sanz, Alba, 1984-; Kedzierska, Anna; Islam, Abul, 1978-; Déu Pons, Jordi; Furney, Simon J.; López Bigas, Núria (Universitat Pompeu Fabra, 2010-02)
    Genes and pathways affected by expression and copy number changes in tumors across projects and cancer types.
  • p27
    Pippa, Raffaella; Espinosa Blay, Lluís; Gundem, Gunes; Garcia Escudero, Ramon; Dominguez, Ana; Orlando, S.; Gallastegui, E.; Saiz, Cristina; Besson, Arnaud; Pujol, Maria Jesus; López Bigas, Núria; Paramio, Jesus M.; Bigas Salvans, Anna; Bachs Valldeneu, Oriol (Universitat Pompeu Fabra, 2011-12)
    The cyclin-cdk (cyclin-dependent kinase) inhibitor p27(Kip1) (p27) has a crucial negative role on cell cycle progression. In addition to its classical role as a cyclin-cdk inhibitor, it also performs cyclin-cdk-independent ...
  • Rafael Palou, Xavier; Schroeder, Michael Philipp, 1986-; López Bigas, Núria (Universitat Pompeu Fabra, 2012-01)
    The aim of SVGMap is helping in the visualisation of experimental data which are associated with some graphical representation. Thus SVGMap browser allows to generate images with colored areas corresponding to the chosen ...
  • Tamborero Noguera, David; López Bigas, Núria; González-Pérez, Abel (Universitat Pompeu Fabra, 2013-02)
    Oncodrive-CIS is a method aimed to identify those copy number alterations (CNAs) leading to larger in cis expression changes that may be useful in elucidating the role of these aberrations in cancer. This is based on the ...
  • González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Déu Pons, Jordi; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Jené i Sanz, Alba, 1984-; Santos, Alberto; López Bigas, Núria (Universitat Pompeu Fabra, 2013-05)
    Mutations, genes and pathways involved in tumorigenesis across 4,623 cancer genomes/exomes from 13 cancer sites. IntOGen-mutations identifies cancer drivers across tumor types. Nature Methods 10, 2013, doi:10.1038/nmeth.2642
  • Tamborero Noguera, David; González-Pérez, Abel; Pérez Llamas, Christian, 1976-; Déu Pons, Jordi; Kandoth, Cyriac; Reimand, Jüri; Lawrence, Michael S.; Getz, Gad; Bader, Gary D.; Ding, Li; López Bigas, Núria (Universitat Pompeu Fabra, 2013-10)
    This file lists the High Confidence Drivers identified as part of the pan-cancer12 initiative, published in the paper Comprehensive identification of mutational cancer driver genes across 12 tumor types" Scientific Reports ...
  • Rubio Pérez, Carlota; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Antolín Hernández, Albert, 1984-; Déu Pons, Jordi; Pérez Llamas, Christian, 1976-; Mestres i López, Jordi; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-03)
    This database contains data on the interactions with therapeutic agents an driver genes contained in Cancer Drivers Database (2014.12). It characterizes the interacting therapeutic agents in terms of clinical phase and ...
  • Barneda Zahonero, Bruna; Román González, Lidia; Collazo, Olga; Rafati, Haleh; Islam, Abul, 1978-; Bussmann, Lars; Di Tullio, Alessandro, 1982-; Andrés, Luisa De; Graf, T. (Thomas); López Bigas, Núria; Mahmoudi, Tokameh; Parra, Maribel (Universitat Pompeu Fabra, 2013-05)
    HDAC7 is a repressor of myeloid genes whose downregulation in pre-B cells is required for transdifferentiation into macrophages.
  • Rubio Pérez, Carlota; Tamborero Noguera, David; Schroeder, Michael Philipp, 1986-; Antolín Hernández, Albert, 1984-; Déu Pons, Jordi; Pérez Llamas, Christian, 1976-; Mestres i López, Jordi; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-03)
    This database contains information on the genes identified as drivers in Rubio-Perez and Tamborero et al. (2015). It contains information on driver identification at mutational, CNA and gene fusion level. Additional ancillary ...
  • Déu Pons, Jordi; Schroeder, Michael Philipp, 1986-; López Bigas, Núria (Universitat Pompeu Fabra, 2014-03)
    Javascript library to create interactive heatmaps within webpages.
  • Schroeder, Michael Philipp, 1986-; Rubio Pérez, Carlota; Tamborero Noguera, David; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2014-06)
    Machine-learning based approach to classify cancer driver genes into to Activating or Loss of Function roles for cancer gene development.
  • Wok
    Pérez Llamas, Christian, 1976- (Universitat Pompeu Fabra, 2014-06)
    Wok is a workflow management system implemented in Python that makes very easy to structure the workflows, parallelize their execution and monitor its progress among other things. It is designed in a modular way allowing ...
  • Déu Pons, Jordi (Universitat Pompeu Fabra, 2014-11)
    Onexus is a modular framework to manage the complete life cycle of data analyses. Data analyses follow these steps: analysis definition, analysis execution, results storing, results browsing and finally results publishing.
  • González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-10)
    OncodriveFM detects candidate cancer driver genes and pathways from catalogs of somatic mutations in a cohort of tumors by computing the bias towards the accumulation of functional mutations (FM bias).This novel approach ...
  • Tamborero Noguera, David; González-Pérez, Abel; López Bigas, Núria (Universitat Pompeu Fabra, 2015-11)
    OncodriveCLUST is a method aimed to identify genes whose mutations are biased towards a large spatial clustering. This method is designed to exploit the feature that mutations in cancer genes, especially oncogenes, often ...

Mostra'n més